Tag: M.W=50-100

Xu, Ming-xian published the artcileOne-pot synthesis of dimethyl carbonate in supercritical CO₂, COA of Formula: C4H10O2, the publication is Gaoxiao Huaxue Gongcheng Xuebao (2014), 28(6), 1334-1339, database is CAplus.

The synthesis of di-Me carbonate (DMC) was studied with carbon dioxide, propylene oxide (PO) and methanol as raw material, potassium methoxide (CH₃OK) as catalyst, calcium chloride (CaCl₂) as dehydration agent. The effects of factors such as the volume ratio of methanol and PO (1-12), stirring speed (0-500 r·min^-1), pressure (5.0-10.0 MPa), temperature (110-190°) and reaction time (0.25-3.0 h) on the synthesis of DMC were investigated. A possible reaction mechanism of one-pot synthesis of di-Me carbonate on CH₃OK was proposed. The results show that the conversion of methanol and the yield of DMC could reach 22.0% and 45.5% resp. under optimized reaction conditions (V_CH3OH : V_PO = 10 : 1, stirring speed 300 r·min^-1, pressure 7.0 MPa, temperature 140°, reaction time 1 h).

Gaoxiao Huaxue Gongcheng Xuebao published new progress about 1589-47-5. 1589-47-5 belongs to ethers-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ether, name is 2-Methoxypropan-1-ol, and the molecular formula is C4H6F3NOS, COA of Formula: C4H10O2.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Knapp, Spring Melody M. published the artcileCatalytic Nitrile Hydration with [Ru(η⁶-p-cymene)Cl₂(PR₂R’)] Complexes: Secondary Coordination Sphere Effects with Phosphine Oxide and Phosphinite Ligands, HPLC of Formula: 16332-06-2, the publication is Organometallics (2013), 32(13), 3744-3752, database is CAplus.

The rates of nitrile hydration reactions were investigated using [Ru(η⁶-p-cymene)Cl₂(PR₂R’)] complexes as homogeneous catalysts, where PR₂R’ = PMe₂(CH₂P(O)Me₂), PMe₂(CH₂CH₂P(O)Me₂), PPh₂(CH₂P(O)Ph₂), PPh₂(CH₂CH₂P(O)Ph₂), PMe₂OH, P(OEt)₂OH. These catalysts were studied because the rate of the nitrile-to-amide hydration reaction was hypothesized to be affected by the position of the hydrogen bond accepting group in the secondary coordination sphere of the catalyst. Experiments showed that the rate of nitrile hydration was fastest when using [Ru(η⁶-p-cymene)Cl₂PMe₂OH]: i.e., the catalyst with the hydrogen bond accepting group capable of forming the most stable ring in the transition state of the rate-limiting step. This catalyst is also active at pH 3.5 and at low temperatures-conditions where α-hydroxynitriles (cyanohydrins) produce less cyanide, a known poison for organometallic nitrile hydration catalysts. The [Ru(η⁶-p-cymene)Cl₂PMe₂OH] catalyst completely converts the cyanohydrins glycolonitrile and lactonitrile to their corresponding α-hydroxyamides faster than previously investigated catalysts. [Ru(η⁶-p-cymene)Cl₂PMe₂OH] is not, however, a good catalyst for acetone cyanohydrin hydration, because it is susceptible to cyanide poisoning. Protecting the -OH group of acetone cyanohydrin was an effective way to prevent cyanide poisoning, resulting in quant. hydration of acetone cyanohydrin acetate.

Organometallics published new progress about 16332-06-2. 16332-06-2 belongs to ethers-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Amide,Ether, name is 2-Methoxyacetamide, and the molecular formula is C3H7NO2, HPLC of Formula: 16332-06-2.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Li, Lei published the artcileOne-step synthesis of dimethyl carbonate from carbon dioxide, propylene oxide and methanol over alkali halides promoted by crown ethers, SDS of cas: 1589-47-5, the publication is Journal of Organometallic Chemistry (2015), 231-236, database is CAplus.

Crown ethers (i.e. [2,4]-dibenzo-18-crown-6 (DBC), 18-crown-6, 15-crown-5 and 12-crown-4) show obvious co-catalytic effect for alkali halides catalyzing one-step synthesis of di-Me carbonate (DMC) from CO₂, propylene oxide and methanol. Especially, the DMC yield of KCl catalyst promoted by DBC can increase by more than five times and reach about 40% under mild reaction conditions (i.e., low mole ratio of methanol and epoxides: 7:3, low initial pressure of CO₂: 1.5 MPa, reaction temperature: 140°, time: 10 h). The optimized molar ratio of KCl to DBC is 2: 1. Due to the good complexing ability between DBC and K⁺, KCl and DBC formed an organometallic complex. Actually, DBC can not only promote the reaction rate and equilibrium of cycloaddition and transesterification reactions, but also prevent side reaction. Importantly, DBC can conveniently achieve high recovery ratio and show excellent reusability.

Journal of Organometallic Chemistry published new progress about 1589-47-5. 1589-47-5 belongs to ethers-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ether, name is 2-Methoxypropan-1-ol, and the molecular formula is C4H10O2, SDS of cas: 1589-47-5.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Ranjitha, K. published the artcileRetention of freshness and isothiocyanates in fresh-cut radish (Raphanus sativus var. Longipinnatus) through glucose dip treatment, HPLC of Formula: 1589-47-5, the publication is Journal of Food Science and Technology (New Delhi, India) (2022), 59(1), 409-415, database is CAplus and MEDLINE.

Experiments were carried out with the objective of enhancing shelf life and maintain quality of fresh-cut radish slices during storage at 8°C. Dip treatment of radish slices in 20 g/L glucose solution for five minutes retained the quality attributes viz., surface color, sensory properties and antioxidant capacity of the slices till six days of storage. Isothiocyanates were also retained better due to glucose dip. Biplot generated through principal component anal. of head space volatiles from fresh and stored radish slices showed that fresh and glucose treated slices grouped together with 4-Me thio-3-butenyl isothiocyanate. Accumulation of sulphurous volatiles such as Me disulfide, di-Me trisulfide, 2-pentanethiol was observed in control (undipped) radish slices, indicating their probable role as spoilage indicator volatiles. Thus, glucose pre-treatment can be considered as a practical method for quality retention of fresh-cut radish.

Journal of Food Science and Technology (New Delhi, India) published new progress about 1589-47-5. 1589-47-5 belongs to ethers-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ether, name is 2-Methoxypropan-1-ol, and the molecular formula is C4H10O2, HPLC of Formula: 1589-47-5.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Nau, Heinz published the artcileWeak acids may act as teratogens by accumulating in the basic milieu of the early mammalian embryo, Quality Control of 16332-06-2, the publication is Nature (London, United Kingdom) (1986), 323(6085), 276-8, database is CAplus and MEDLINE.

Among the 11 drugs or chems. which are well-documented human teratogens, 8 (or their main metabolites) are weak acids whereas none is a weak base. Moreover, 23 out of 32 acids tested were teratogenic in at least 1 animal species. The acidic property of drugs may therefore be an important determinant of teratogenicity. The intracellular pH (pH_i) of the mouse and rat embryo is higher than that of maternal plasma, as determined by the relative accumulation of dimethadione  [695-53-4]. The antiepileptic drug valproic acid  [99-66-1] and its pharmacol. active unsaturated metabolite accumulate in embryonic tissue to higher concentrations than in maternal plasma, whereas the essentially neutral amide of valproic acid (valpromide  [2430-27-5]) or ethosuximide  [77-67-8] do not accumulate in the embryo; in the rat the pH_i of the embryo decreases with advancing gestation; in general agreement with the pH partiton hypothesis, the exposure of the embryo to valproic acid also decreases significantly during that period. Furthermore, the amides of 2 weak acid teratogens, valpromide and methoxyacetamide  [16332-06-2], and ethosuximide, are much less teratogenic than their acid counterparts. Thus, weakly acidic drugs, by virtue of their physicochem. nature, accumulate in the early embryo with its relatively high pH_i.

Nature (London, United Kingdom) published new progress about 16332-06-2. 16332-06-2 belongs to ethers-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Amide,Ether, name is 2-Methoxyacetamide, and the molecular formula is C3H7NO2, Quality Control of 16332-06-2.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Rahmatpour, Ali published the artcileCross-linked poly(N-vinylpyrrolidone)-titanium tetrachloride complex: A novel stable solid TiCl₄ equivalent as a recyclable polymeric Lewis acid catalyst for regioselective ring-opening alcoholysis of epoxides, Formula: C4H10O2, the publication is Applied Organometallic Chemistry (2021), 35(11), e6385, database is CAplus.

Crosslinked poly(N-vinylpyrrolidone) resin beads were prepared as macromol. ligand precursors by suspension copolymerization of N-vinyl-2-pyrrolidone and N,N’-methylenebisacrylamide (MBA) as a crosslinking agent in water. Subsequently, the resulting polymer carrier precursor was readily combined with titanium tetrachloride to form a stable polymeric coordination complex (PNVP/TiCl₄), and this novel stable TiCl₄ equivalent evaluated as a heterogeneous and reusable solid Lewis acid catalyst for the regio-and stereoselective nucleophilic ring opening of various epoxides with various alcs. to prepare β-alkoxy alcs. in excellent yields without generating any waste. The MBA-crosslinked PNVP and resultant catalyst were characterized by Fourier transform IR spectroscopy (FT-IR), field-emission scanning electron microscope (FE-SEM), energy dispersive X-ray (EDX), inductively coupled plasma (ICP), and thermogravimetric anal. (TGA) techniques. Moreover, the catalyst is very stable, easily separated, and reused at least five times without significant loss of activity. In terms of scope, yields, the amount of catalyst used, and reaction time, the PNVP-TiCl₄ complex catalyst is an improvement over previously reported heterogeneous catalysts for ring opening of epoxides methods. Further, the exptl. outcome revealed that using the copolymer beads as carriers with a high percentage of crosslinking and the high mesh size leads had an adverse effect on the reaction rate.

Applied Organometallic Chemistry published new progress about 1589-47-5. 1589-47-5 belongs to ethers-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ether, name is 2-Methoxypropan-1-ol, and the molecular formula is C4H10O2, Formula: C4H10O2.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Arbulu, Maria published the artcileCharacterisation of the flavour profile from Graciano Vitis vinifera wine variety by a novel dual stir bar sorptive extraction methodology coupled to thermal desorption and gas chromatography-mass spectrometry, COA of Formula: C4H10O2, the publication is Analytica Chimica Acta (2013), 41-48, database is CAplus and MEDLINE.

A new anal. technique was developed for the study of the organoleptic compounds (flavor profile) of the Graciano Vitis vinifera wine variety. The cv. Graciano is a singular variety of red grapes with its origins in La Rioja and Navarra (northern Spain). This variety transfers an intense red color, aroma and high acidity to musts and provides greater longevity and, consequently, a better capacity for aging wine. A new dual-stir bar sorptive extraction approach coupled with thermal desorption (TD) and GC-MS has been used to extract the volatile and semivolatile compounds In this extraction step, the optimal values for the exptl. variables were obtained through the Response Surface Methodol. (RSM). Full scan chromatogram data were evaluated with two deconvolution software tools, and the results were compared. The volatile and semivolatile components were identified with an MS match ≥80%. As a result, the flavor metabolome of the Graciano Vitis vinifera wine variety was obtained, and 205 metabolites were identified using different databases. These metabolites were grouped into esters, acids, alcs., nitrogen compounds, furans, lactones, ketones, aldehydes, phenols, terpenes, norisoprenoids, sulfur compounds, acetals and pyrans. The majority of the metabolites observed had already been reported in the literature; however, this work also identified new, previously unreported metabolites in red wines, which may be characteristic of the Graciano variety.

Analytica Chimica Acta published new progress about 1589-47-5. 1589-47-5 belongs to ethers-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ether, name is 2-Methoxypropan-1-ol, and the molecular formula is C4H10O2, COA of Formula: C4H10O2.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Nirmala, Muthukumaran published the artcileRuthenium(II) complexes incorporating salicylaldiminato-functionalized N-heterocyclic carbene ligands as efficient and versatile catalysts for hydration of organonitriles, Category: ethers-buliding-blocks, the publication is Inorganica Chimica Acta (2016), 134-144, database is CAplus.

Authors describe a new synthetic procedure for synthesis of ruthenium(II) complexes containing salicylaldiminato functionalized mixed N-heterocyclic carbene (NHC) ligand and phosphine co-ligand. The complexes (3a–3d) have been obtained in good to excellent yields by transmetalation from the corresponding Ag-NHC complexes (2a–2d) as carbene transfer reagents. All the [Ru-NHC] complexes have been characterized by elemental analyses, spectroscopic methods as well as ESI mass spectrometry. The ligands 1a–1d show their versatility by switching to be O,N,C-chelating in these ruthenium(II) complexes. The resulting complexes have been evaluated as potential catalysts for the selective hydration of nitriles to primary amides, and related amide bond forming reactions, in environmentally friendly medium. The reaction tolerated ether, hydroxyl, nitro, bromo, formyl, pyridyl, benzyl and alkyl functional groups. The catalyst was stable for weeks and could be recovered and reused more than six times without significant loss of activity.

Inorganica Chimica Acta published new progress about 16332-06-2. 16332-06-2 belongs to ethers-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Amide,Ether, name is 2-Methoxyacetamide, and the molecular formula is C3H7NO2, Category: ethers-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Tamura, Masazumi published the artcileSubstrate-Specific Heterogeneous Catalysis of CeO₂ by Entropic Effects via Multiple Interactions, Synthetic Route of 16332-06-2, the publication is ACS Catalysis (2015), 5(1), 20-26, database is CAplus.

Achieving complete substrate specificity through multiple interactions like an enzyme is one of the ultimate goals in catalytic studies. Herein, we demonstrate that multiple interactions between the CeO₂ surface and substrates are the origin of substrate-specific hydration of nitriles in water by CeO₂, which is exclusively applicable to the nitriles with a heteroatom (N or O) adjacent to the α-carbon of the CN group but is not applicable to the other nitriles. Kinetic studies reveal that CeO₂ reduces the entropic barrier (TΔS‡) for the reaction of the former reactive substrate, leading to 10⁷-fold rate enhancement compared with the latter substrate. D. functional theory (DFT) calculations confirmed multiple interaction of the reactive substrate with CeO₂, as well as preferable approximation and alignment of the nitrile group of the substrate to the active OH group on CeO₂ surface. This can lead to the reduction of the entropic barrier. This is the first example of an entropy-driven substrate-specific catalysis of a nonporous metal oxide surface, which will provide a new design strategy for enzyme-inspired synthetic catalysts.

ACS Catalysis published new progress about 16332-06-2. 16332-06-2 belongs to ethers-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Amide,Ether, name is 2-Methoxyacetamide, and the molecular formula is C3H6O2, Synthetic Route of 16332-06-2.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Sakdasri, Winatta published the artcileContinuous production of biofuel from refined and used palm olein oil with supercritical methanol at a low molar ratio, Recommanded Product: 2-Methoxypropan-1-ol, the publication is Energy Conversion and Management (2015), 934-942, database is CAplus.

The high energy consumption and high environmental impact in the supercritical methanol (SCM) process primarily originates from the preheating of reactants and the recovery of excess alcs. This work demonstrated the synthesis of biofuel using a lowered methanol to oil molar ratio of 12:1, instead of the 40:1-42:1 ratios that are commonly employed in conventional SCM. The apparent d. of the reacting mixture was measured and applied to accurately calculate residence times in a continuous reactor. The effects of residence time were considered from 10 to 25 min. The results revealed that excessive residence times reduced the ester content, especially for unsaturated esters, in the resulting biofuel. A residence time of 20 min was recommended to simultaneously achieve a maximum ester content of 90% and a triglyceride conversion of up to 99%. Used palm olein oil with high free fatty acid (4.56 weight%) can be employed as a feedstock and give a maximum ester content of 80%. In addition, the side reaction between glycerol and methanol at 400 °C and 15 MPa showed a pos. effect in increasing fuel yield by 2%-7%.

Energy Conversion and Management published new progress about 1589-47-5. 1589-47-5 belongs to ethers-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ether, name is 2-Methoxypropan-1-ol, and the molecular formula is C4H10O2, Recommanded Product: 2-Methoxypropan-1-ol.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem