Tag: M.W=150-200

Dong, Wenbo published the artcileA highly stable all-in-one photocatalyst for aryl etherification: the Ni^II embedded covalent organic framework, Name: 2-Methoxynaphthalene, the publication is Green Chemistry (2021), 23(16), 5797-5805, database is CAplus.

The efficient conversion of aryl bromides to the corresponding aryl alkyl ethers by dual Ni/photocatalysis has seen great progress, but difficulties of recycling the photosensitizer or Ni complexes cause problems of sustainability. Here, the authors report the design of a novel, highly stable vinyl bridge 2-dimensional covalent organic framework (COF) containing Ni, which combines the role of photosensitizer and reactive site. The as-prepared sp²c-COF_dpy-Ni acts as an efficient heterogeneous photocatalyst for C-O cross coupling. The sp²c-COF_dpy-Ni can be completely recovered and used repeatedly without loss of activity, overcoming the limitations of the prior methods. Preliminary studies reveal that strong interlayer electron transfer may facilitate the generation of the proposed intermediate sp²c-COF_dpy-Ni^I in a bimol. and self-sustained manner. This all-in-one heterogeneous photocatalyst exhibits good compatibility of substrates and tolerance of functional groups. The successful attempt to expand the 2-dimensional COFs with this new catalyst into photocatalytic organic transformation opens an avenue for photoredox/transition metal mediated coupling reactions.

Green Chemistry published new progress about 93-04-9. 93-04-9 belongs to ethers-buliding-blocks, auxiliary class Naphthalene,Ether, name is 2-Methoxynaphthalene, and the molecular formula is C11H10O, Name: 2-Methoxynaphthalene.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Molander, Gary A. published the artcileAccessing Molecularly Complex Azaborines: Palladium-Catalyzed Suzuki-Miyaura Cross-Couplings of Brominated 2,1-Borazaronaphthalenes and Potassium Organotrifluoroborates, Product Details of C8H11BO3, the publication is Journal of Organic Chemistry (2014), 79(14), 6663-6678, database is CAplus and MEDLINE.

Despite their potential applications in both medicinal chem. and materials science, there have been limited reports on the functionalization of 2,1-borazaronaphthalenes since their discovery in 1959. To access new chem. space and build mol. complexity, the Suzuki-Miyaura cross-coupling of brominated 2,1-borazaronaphthalenes has been investigated. The palladium-catalyzed cross-coupling proceeds with an array of potassium (hetero)aryltrifluoroborates in high yield with low catalyst loadings under mild reaction conditions. By the use of a high-yielding bromination of various 2,1-borazaronaphthalenes to generate electrophilic azaborine species, a library of 3-(hetero)aryl and 3,6-diaryl-2,1-borazaronaphthalenes has been synthesized.

Journal of Organic Chemistry published new progress about 725251-81-0. 725251-81-0 belongs to ethers-buliding-blocks, auxiliary class Boronic acid and ester,Benzene,Ether,Boronic Acids,Boronic acid and ester, name is (3-Methoxy-5-methylphenyl)boronic acid, and the molecular formula is C8H11BO3, Product Details of C8H11BO3.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Peng, Bing published the artcilePhotodegradation of naproxen using CuZnAl-layered double hydroxides as photocatalysts, Application In Synthesis of 93-04-9, the publication is CrystEngComm (2022), 24(28), 5080-5089, database is CAplus.

Naproxen (NPX), as a typical pharmaceutical and personal care product (PPCP), is frequently detected in water and is difficult to remove effectively by conventional methods. Layered double hydroxides, as highly efficient photocatalysts, have not been used in photocatalysis of PPCP. In this study, CuZnAl-layered double hydroxide (CuZnAl-LDH) was prepared and its performance in the photocatalytic degradation of NPX under UV light illumination was investigated. The results indicated that the NPX photodegradation is considerably enhanced by CuZnAl-LDH with an efficiency of 98.25% in the optimal conditions, which was obviously more than that under pure light condition (efficiency less than 30%). In addition, the CuZnAl-LDH photocatalyst exhibited superior photocatalytic stability confirmed by the analyses of the catalyst structure, morphol., and cycle experiments Moreover, by the comparison of optical properties of ZnAl-LDH and CuZnAl-LDH, it was found that Cu²⁺ can broaden light absorption and facilitate the separation of photogenerated charges electrons (e^–) and holes (h⁺), and in the CuZnAl-LDH system, the formation mechanism of active species complies with the mechanisms of the ligand-to-metal charge transfer (LMCT) from the 2p orbital of oxygen to the 3d orbital of M²⁺ and of the d-d transition of Cu²⁺ ions of the CuO₆ unit. Besides, ESR and scavenging tests revealed that the photocatalytic process was enhanced by the synergistic effect of h⁺, O₂^–, and OH, which displayed the sequence of h⁺ > ^.O₂^– > ^.OH. Finally, the intermediate products were identified by LCMS-IT-TOF, and no intermediates with greater toxicity than NPX were produced. The possible degradation pathway of NPX was proposed involving the decarboxylation, demethylation, and hydroxylation reactions and ring-opening based on intermediates. These results are expected to provide new data on the photodegradation of naproxen.

CrystEngComm published new progress about 93-04-9. 93-04-9 belongs to ethers-buliding-blocks, auxiliary class Naphthalene,Ether, name is 2-Methoxynaphthalene, and the molecular formula is C11H10O, Application In Synthesis of 93-04-9.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Lou, Qian published the artcileDegradation of sulfonamides in aquaculture wastewater by laccase-syringaldehyde mediator system: Response surface optimization, degradation kinetics, and degradation pathway, Safety of 4-Hydroxy-3,5-dimethoxybenzaldehyde, the publication is Journal of Hazardous Materials (2022), 128647, database is CAplus and MEDLINE.

As a new type of environmental pollutant, environmental antibiotic residues have attracted widespread attention, and the degradation and removal of antibiotics has become an engaging topic for scholars. In this paper, Novozym 51003 industrialized laccase and syringaldehyde were combined to degrade sulfonamides in aquaculture wastewater. Design Expert10 software was used for multiple regression anal., and a response surface regression model was established to obtain the optimal degradation parameters. In the actual application, the degradation system could maintain a stable performance within 9 h, and timely supplement of the mediator could achieve a better continuous degradation effect. Low concentrations of heavy metals and organic matter would not significantly affect the degradation performance of the laccase-mediator system, making the degradation system suitable for a wide range of water quality. Enzymic reaction kinetics demonstrated a strong affinity of sulfadiazine to the substrate. Ten degradation products were speculated using high-resolution mass spectrum based on the mass/charge ratios and the publication results. Four types of possible degradation pathways of sulfadiazine were deduced. This work provides a practical method for the degradation and removal of sulfonamide antibiotics in actual sewage.

Journal of Hazardous Materials published new progress about 134-96-3. 134-96-3 belongs to ethers-buliding-blocks, auxiliary class Immunology/Inflammation,COX,Natural product, name is 4-Hydroxy-3,5-dimethoxybenzaldehyde, and the molecular formula is C9H10O4, Safety of 4-Hydroxy-3,5-dimethoxybenzaldehyde.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Yang, Yue-Qin published the artcileNitrogen-doped carbon anchored ruthenium nanoparticles for biofuel upgrade, Safety of 4-Hydroxy-3,5-dimethoxybenzaldehyde, the publication is Fuel (2022), 123100, database is CAplus.

The development of efficient catalysts is of great significance for the hydrodeoxygenation (HDO) of renewable biomass into value-added biofuel and chems. to mitigate the environmental and energy menace. Herein, we report a sustainable strategy to fabricate ruthenium nanoparticles (NPs) anchored on defective nitrogen-doped carbon (Ru@NC) via a facile pyrolysis of a mixture of ruthenium trichloride and urea with carbon support. The highly distributed Ru NPs, constituted by N-enriched graphene shells, have been established as an excellent catalyst for the selective HDO of lignin- and furan- derivatives toward biofuel upgrade. Impressively, Ru@NC exhibits enhanced catalytic performance to com. Ru/C, which could be attributed to the presence of the ensemble effects resulting from defective graphene sheet coverage on the Ru surface. Notably, the prepared catalyst was not affected after five successive reaction cycles, demonstrating superior stability and reproducibility. We envision that this work may pave the way for the development of highly efficient novel metal catalysts for heterogeneous catalytic HDO reactions in sustainable energy conversion.

Fuel published new progress about 134-96-3. 134-96-3 belongs to ethers-buliding-blocks, auxiliary class Immunology/Inflammation,COX,Natural product, name is 4-Hydroxy-3,5-dimethoxybenzaldehyde, and the molecular formula is C13H10O3, Safety of 4-Hydroxy-3,5-dimethoxybenzaldehyde.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Zhang, Chenglu published the artcileTotal synthesis of 3-carbonyl-10-demethyl-12-methoxyabietane, Safety of 2-Isopropylanisole, the publication is Liaoning Shifan Daxue Xuebao, Ziran Kexueban (2011), 34(1), 71-73, database is CAplus.

Total synthesis of 3-carbonyl-10-demethyl-12-methoxyabietane was explored according to the strategy of AC->ABC. The 3-carbonyl-10-demethyl-12-methoxyabietane was synthesized from 2-isopropyl-1-methoxybenzene by bromination in the presence of the catalyst ammonium phosphomolybdate, the addition of ethylene oxide and further bromination. All intermediates and target product were confirmed by IR, ¹H NMR and MS. In conclusion, a simple high yield synthetic route has been developed and the target mol. was successfully synthesized.

Liaoning Shifan Daxue Xuebao, Ziran Kexueban published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C16H12O, Safety of 2-Isopropylanisole.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Lu, Qixing published the artcileC-H heteroarylation of aromatics via catalyst free S_N2′ coupling cycloaromatization, HPLC of Formula: 93-04-9, the publication is Green Chemistry (2022), 24(11), 4399-4404, database is CAplus.

The construction of a carbon-carbon bond is the most fundamental aspect of synthetic chem. In this study, authors developed a catalyst-free S_N2′ reaction of β-OTf-substituted enamides with aromatics to obtain aryl-substituted aza-1,4-dicarbonyl compounds that can be in situ transformed into aryl-imidazole, aryl-thiazole, and aryl-oxazole in one-pot operation, thus achieving C-H heteroarylation of aromatics This simple, efficient, clean and scalable strategy, which provides difficult-to-realize biaryl products, is compatible with various aromatics having varying complexities. This method can be used for the late-stage modification of various com. pharmaceuticals or functional materials and offers an orthogonal approach for constructing biaryl compounds

Green Chemistry published new progress about 93-04-9. 93-04-9 belongs to ethers-buliding-blocks, auxiliary class Naphthalene,Ether, name is 2-Methoxynaphthalene, and the molecular formula is C11H10O, HPLC of Formula: 93-04-9.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Li, Yonglong published the artcileTunable Photocatalytic Two-Electron Shuttle between Paired Redox Sites on Halide Perovskite Nanocrystals, Recommanded Product: 2-Methoxynaphthalene, the publication is ACS Catalysis (2022), 12(10), 5903-5910, database is CAplus.

Perovskite semiconductors as advanced solar energy-converting materials are promising catalysts for photoredox organic synthesis. Despite the high concentration of charge carriers generated on the perovskite surface, efficient utilization of these nonequilibrium and shambolic energetic carriers to trigger a chem. reaction remains a hot and challenging subject. Here, we report a photon-mediated electron shuttle between paired redox sites on perovskite nanocrystals for the reformation of highly stable carbon-halogen bonds, where both surface electrons and holes are utilized simultaneously. The photo-redox cascade can be effortlessly tailored by precise control of the surface-reducing/-oxidizing reaction rates, which unlocks the transformation for a wide range of (het)arenes. This work demonstrates colloidal perovskite photocatalysts for the direct installation of more than 10 different synthetically important functional groups onto arenes and heteroarenes.

ACS Catalysis published new progress about 93-04-9. 93-04-9 belongs to ethers-buliding-blocks, auxiliary class Naphthalene,Ether, name is 2-Methoxynaphthalene, and the molecular formula is C11H10O, Recommanded Product: 2-Methoxynaphthalene.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Xu, Ren-Rui published the artcilePalladium-catalyzed cascade Heck-type thiocarbonylation for the synthesis of functionalized thioesters, Safety of 2-Methoxynaphthalene, the publication is Organic Chemistry Frontiers (2022), 9(5), 1417-1421, database is CAplus.

A palladium-catalyzed cascade Heck-type cyclization and carbonylation reaction has been developed for the synthesis of functionalized thioesters. With arylsulfonyl chlorides as odorless and readily available sulfur sources, a variety of thioesters were obtained in moderate to good yields with good functional group compatibility. In this system, Mo(CO)₆ acts as both a convenient CO surrogate and a suitable reductant.

Organic Chemistry Frontiers published new progress about 93-04-9. 93-04-9 belongs to ethers-buliding-blocks, auxiliary class Naphthalene,Ether, name is 2-Methoxynaphthalene, and the molecular formula is C8H8O3, Safety of 2-Methoxynaphthalene.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Zhang, Hongliang published the artcileElectrophilic amidomethylation of arenes with DMSO/MeCN reagents, Related Products of ethers-buliding-blocks, the publication is Organic Chemistry Frontiers (2022), 9(9), 2430-2437, database is CAplus.

An efficient electrophilic amidomethylation of aromatics was described to construct N-benzylic amides, which are core structures in drugs and natural products. The simple combination of DMSO (DMSO, as the CH₂ unit) and acetonitrile (MeCN, as the nitrogen unit) as a highly active amidomethylation reagent enables the efficient C-C, C-N and C=O bond construction. Notably, this method provides a practical protocol for the efficient preparation of deuterated benzylamine derivatives with easily available d₆-DMSO or d₃-MeCN, and is also applied in the concise synthesis of Nonivamide and Pimavanserin.

Organic Chemistry Frontiers published new progress about 93-04-9. 93-04-9 belongs to ethers-buliding-blocks, auxiliary class Naphthalene,Ether, name is 2-Methoxynaphthalene, and the molecular formula is C15H24S, Related Products of ethers-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem