Tag: M.W=150-200

Lv, Shao-Dong published the artcileTotal synthesis of (±)-Scrodentoid A, Name: 2-Isopropylanisole, the publication is Tetrahedron (2019), 75(52), 130774, database is CAplus.

An efficient total synthesis of scrodentoid A (I) was accomplished starting from a Hagemann’s ester and a substituted (2-bromoethyl)benzene. Key reactions in this synthesis include C-alkylation of the Hagemann’s ester, 6-endo-Trig cationic cyclization of an enone and Lewis acid promoted isomerization of a cis-fused ketone.

Tetrahedron published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, Name: 2-Isopropylanisole.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Dhami, Kewal S. published the artcileCarbon-13 N.M.R. studies. VIII. 13C spectra of some substituted anisoles, Computed Properties of 2944-47-0, the publication is Canadian Journal of Chemistry (1966), 44(23), 2855-66, database is CAplus.

The 13C N.M.R. spectra of a series of 40 substituted anisoles were obtained to investigate the effects of substitution on the aromatic and methoxyl carbon shieldings. This work extends our studies on the variations of chem. shifts of C nuclei in side chains of aryl derivatives The question of steric hindrance to conjugative interaction of a methoxyl group with an aromatic ring is considered on the basis of the present results. Evidence of a steric effect in compounds in which both ortho positions are substituted is presented. 18 references.

Canadian Journal of Chemistry published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, Computed Properties of 2944-47-0.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Zhu, Runqing published the artcilepara-selective hydroxylation of alkyl aryl ethers, Quality Control of 2944-47-0, the publication is Chemical Communications (Cambridge, United Kingdom) (2021), 57(97), 13190-13193, database is CAplus and MEDLINE.

Para-Selective hydroxylation of alkyl aryl ethers is established, which proceeds with a ruthenium(II) catalyst, hypervalent iodine(III) and trifluoroacetic anhydride via a radical mechanism. This protocol tolerates a wide scope of substrates and provides a facile and efficient method for preparing clin. drugs monobenzone and pramocaine on a gram scale.

Chemical Communications (Cambridge, United Kingdom) published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C15H20O6, Quality Control of 2944-47-0.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Zhang, Jintong published the artcileNickel-Catalyzed Enantioselective Arylative Activation of Aromatic C-O Bond, COA of Formula: C11H10O, the publication is Journal of the American Chemical Society (2021), 143(44), 18380-18387, database is CAplus and MEDLINE.

The pioneering nickel-catalyzed cross-coupling of C-O electrophiles was unlocked by Wenkert in the 1970s; however, the transition-metal-catalyzed asym. activation of aromatic C-O bonds has never been reported. Herein the first enantioselective activation of an aromatic C-O bond is demonstrated via the catalytic arylative ring-opening cross-coupling of diarylfurans. This transformation is facilitated via nickel catalysis in the presence of chiral N-heterocyclic carbene ligands, and chiral 2-aryl-2′-hydroxy-1,1′-binaphthyl (ArOBIN) skeletons are delivered axially in high yields with high ee. Moreover, this versatile skeleton can be transformed into various synthetic useful intermediates, chiral catalysts, and ligands by using the CH- and OH-based modifiable sites. This chem. features mild conditions and good atom economy.

Journal of the American Chemical Society published new progress about 93-04-9. 93-04-9 belongs to ethers-buliding-blocks, auxiliary class Naphthalene,Ether, name is 2-Methoxynaphthalene, and the molecular formula is C9H6FNO, COA of Formula: C11H10O.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Barbieri, G. published the artcileChemical shift nonequivalence and optical activity in tricarbonyl(arene)chromium compounds, Product Details of C10H14O, the publication is Organic Magnetic Resonance (1971), 3(4), 503-4, database is CAplus.

For ortho-substituted tricarbonyl(iso-propylbenzene)chromium in CDCl3, the NMR spectra showed diastereotopic nonequivalent for the gem-dimethyl groups. For ortho substituents NH2, NMe2, and OMe, splitting of the iso-Pr Me groups was 0.100, 0.111, and 0.119 ppm, resp. When OMe-substituted compound (the most stable) was eluted with methylcyclohexane from an activated lactose column in an N atm, the optical rotation [α]2D0 of the fractions changed progressively from -5° to +6°.

Organic Magnetic Resonance published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, Product Details of C10H14O.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Nakao, Yoshiaki published the artcileCross-Coupling Reactions through the Intramolecular Activation of Alkyl(triorgano)silanes, COA of Formula: C10H14O, the publication is Angewandte Chemie, International Edition (2010), 49(26), 4447-4450, S4447/1-S4447/34, database is CAplus and MEDLINE.

Cross-coupling reactions of 2-(2-hydroxyprop-2-yl)phenyl-substituted alkylsilanes, e.g., I, with a variety of aryl bromides/chlorides, e.g., 4-chlorobenzonitrile, proceeded in the presence of palladium and copper catalysts to give alkyl-coupled products, e.g., 4-butylbenzonitrile. The use of K₃PO₄ allowed for highly chemoselective alkyl coupling with both primary and secondary alkyl groups.

Angewandte Chemie, International Edition published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, COA of Formula: C10H14O.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Knorrscheidt, Anja published the artcileAccessing chemo- and regioselective benzylic and aromatic oxidations by protein engineering of an unspecific peroxygenase, COA of Formula: C11H10O, the publication is ACS Catalysis (2021), 11(12), 7327-7338, database is CAplus and MEDLINE.

Unspecific peroxygenases (UPOs) enable oxyfunctionalizations of a broad substrate range with unparalleled activities. Tailoring these enzymes for chemo- and regioselective transformations represents a grand challenge due to the difficulties in their heterologous productions. Herein, we performed protein engineering in Saccharomyces cerevisiae using the MthUPO from Myceliophthora thermophila. More than 5300 transformants were screened. This protein engineering led to a significant reshaping of the active site as elucidated by computational modeling. The reshaping was responsible for the increased oxyfunctionalization activity, with improved k_cat/K_m values of up to 16.5-fold for the model substrate 5-nitro-1,3-benzodioxole. Moreover, variants were identified with high chemo- and regioselectivities in the oxyfunctionalization of aromatic and benzylic carbons, resp. The benzylic hydroxylation was demonstrated to perform with enantioselectivities of up to 95% ee. The proposed evolutionary protocol and rationalization of the enhanced activities and selectivities acquired by MthUPO variants represent a step forward toward the use and implementation of UPOs in biocatalytic synthetic pathways of industrial interest.

ACS Catalysis published new progress about 93-04-9. 93-04-9 belongs to ethers-buliding-blocks, auxiliary class Naphthalene,Ether, name is 2-Methoxynaphthalene, and the molecular formula is C11H10O, COA of Formula: C11H10O.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Wang, Qinghe published the artcileSynthesis of diaryliodonium tetrafluoroborates, Recommanded Product: 2-Isopropylanisole, the publication is Zhongguo Yaowu Huaxue Zazhi (2000), 10(4), 288-289, database is CAplus.

Two diaryliodonium tetrafluoroborates bis(3-isopropyl-4-methoxyphenyl)iodonium tetrafluoroborate and bis(4-methoxyphenyl)iodonium tetrafluoroborate were synthesized by iodination of 2-isopropylphenyl Me ether or methoxybenzene in acetic anhydride in the presence of HNO₃ and trifluoroacetic acid at -30° and salification with NaBF₄.

Zhongguo Yaowu Huaxue Zazhi published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C8H6ClN, Recommanded Product: 2-Isopropylanisole.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Amaro, Ana L. published the artcileMultitrait analysis of fresh-cut cantaloupe melon enables discrimination between storage times and temperatures and identifies potential markers for quality assessments, Application In Synthesis of 2944-47-0, the publication is Food Chemistry (2018), 222-231, database is CAplus and MEDLINE.

Fresh-cut cantaloupe melon is valued for its aroma but is highly perishable. Temperature of storage (typically 0-5 °C) is critical for maintaining fresh-cut melon quality, but often reaches 10 °C during transportation and in retail outlets. A comparison amongst 0, 5 and 10 °C storage temperatures for fresh-cut melon over 14 days reveals that storage at 0 °C is optimal for avoiding increases in microbial load and loss of vitamin C especially at later time points. However, higher temperatures maintain better the balance of esters (acetate vs. non-acetate) and phenolic content. The whole volatile organic compound (VOC) profile can be used to discriminate both time and temperature effects especially at earlier time points. Potential VOC markers for changes in vitamin C from day 0 to day 6 of storage (3-Me butane nitrile) and temperature (limonene) are identified through a multi-trait anal.

Food Chemistry published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, Application In Synthesis of 2944-47-0.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Auersvald, Milos published the artcileElectrometric bromine number as a suitable method for the quantitative determination of phenols and olefins in hydrotreated pyrolysis bio-oils, Application of 2-Methoxynaphthalene, the publication is Talanta (2021), 122001, database is CAplus and MEDLINE.

Bio-oils after hydrotreatment can still contain significant amount of phenols and cyclic olefins as the products of an incomplete deoxygenation. The removal of these compounds would be necessary to produce suitable components for automotive fuels. However, no routine method currently exists for the reliable determination of these groups in hydrotreated bio-oils (HBOs). In this paper, we analyzed 140 different pure oxygenates as model compounds using the bromine number method (ASTM D1159) observing that most compounds present in HBOs react with one equivalent of bromine. The determination of phenols using bromine number method in crude bio-oil is complicated especially by the presence of guaiacols and syringols that react with more than one equivalent of bromine and, thus, the obtained result is significantly overestimated. Further we optimized the chromatog. separation of hydrocarbons from HBOs for the selective determination of olefins content. As no other reactive compounds under the conditions of the method, besides phenols and olefins, were observed in HBOs, the difference between HBO bromine number (before hydrocarbons separation) and olefins content correspond to the total amount of phenols. The method was finally applied to 11 HBOs with different content of oxygen, providing a good correlation between phenols and oxygen content.

Talanta published new progress about 93-04-9. 93-04-9 belongs to ethers-buliding-blocks, auxiliary class Naphthalene,Ether, name is 2-Methoxynaphthalene, and the molecular formula is C11H10O, Application of 2-Methoxynaphthalene.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem