Tag: M.W=100-150

Phan Thi Thanh, Nga; Dang Thi Thu, Huong; Tone, Masaya; Inoue, Hayato; Iwasa, Seiji published the artcile< Synthesis of Oxindole Derivatives via Intramolecular C-H Insertion of Diazoamides Using Ru(II)-Pheox Catalyst>, Electric Literature of 10541-78-3, the main research area is oxindole preparation regioselective; diazoacetamide preparation insertion reaction ruthenium catalyst.

This work presented the efficient intramol. aromatic C-H insertion of diazoacetamide. The diazo compounds (except for 1k) were converted into their corresponding oxindoles via an intramol. C-H insertion reaction in the presence of a Ru catalyst. The Ru-Pheox catalyst was shown to be highly efficient in this transformation in terms of the regioselectivity, producing the desired products in excellent yield (99%). The efficiency of the Ru catalyst reached 580 (TON) and 156 min-1 (TOF).

Tetrahedron published new progress about Acetamides Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation) (diazo). 10541-78-3 belongs to class ethers-buliding-blocks, and the molecular formula is C8H11NO, Electric Literature of 10541-78-3.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Piatti, Erik; Guglielmero, Luca; Tofani, Giorgio; Mezzetta, Andrea; Guazzelli, Lorenzo; D′Andrea, Felicia; Roddaro, Stefano; Pomelli, Christian Silvio published the artcile< Ionic liquids for electrochemical applications: Correlation between molecular structure and electrochemical stability window>, Product Details of C3H7BrO, the main research area is ionic liquid electrochem application mol structure stability.

Ionic gating has emerged as an effective and versatile tool to tune the charge-carrier d. of a material and control its electronic ground state, as well as to develop low-temperature devices such as electrochem. transistors. Ionic liquids are a promising gating agent due to their high thermal- and electrochem. stability for both fundamental and applied research. However, the understanding of the correlation between the mol. structure of ionic liquids and their electrochem. stability is quite limited. For this reason, this study aims at determining the guidelines for synthesizing ionic liquids suitable for their use as electrolytes at low temperatures A series of twenty-three ionic liquids having various ammonium cations, composed of three ′ ′short chains ′ ′ and one ′ ′long chain ′ ′, and Tf2N as the anion, were synthesized. Afterwards, their thermal behavior was determined to identify those ionic liquids exhibiting Tg < -50 °C. The anodic and cathodic limits of the selected ionic liquids were measured via linear-sweep voltammetry using an electrochem. transistor configuration, working at -33 °C. Electrochem. windows having absolute values from 2.9 to 5.7 V were measured. Overall, five guidelines were determined from the exptl. results: first, the cations influence both cathodic and anodic limits; second, the asym. ammonium cations show larger electrochem. stability than sym. ones; third, the electrochem. stability decreases at the increase of the length of the ′ ′long chain ′ ′; fourth, alkyl long chains show a larger anodic limit, but smaller cathodic limit than ether long chains having the same length; fifth, the ether chain with largest electrochem. stability comprises three carbon atoms and one oxygen. Journal of Molecular Liquids published new progress about Anions. 6482-24-2 belongs to class ethers-buliding-blocks, and the molecular formula is C3H7BrO, Product Details of C3H7BrO.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers can again be classified into two varieties: if the alkyl or aryl groups are the same on both sides of the oxygen atom, 111-90-0, formula is C6H14O3, Name is Diethylene Glycol Monoethyl Ether. Then it is a simple or symmetrical ether, whereas if they are different, the ethers are called mixed or unsymmetrical ethers. Recommanded Product: Diethylene Glycol Monoethyl Ether.

Karrar, Emad;Ahmed, Isam A. Mohamed;Wei, Wei;Sarpong, Frederick;Proestos, Charalampos;Amarowicz, Ryszard;Oz, Emel;Sheikha, Aly Farag El;Allam, Ayman Y.;Oz, Fatih;Wang, Xingguo research published 《 Characterization of Volatile Flavor Compounds in Supercritical Fluid Separated and Identified in Gurum (Citrulluslanatus Var. colocynthoide) Seed Oil Using HSME and GC-MS》, the research content is summarized as follows. In this study, the volatile compound profiles of gurum seed oil were determined using two methods: supercritical CO2 extraction (SFE) and the screw press process (SPP). For volatile compounds extraction and identification, headspace solid-phase micro-extraction (HS-SPME) and GC-MS were used, resp. A total number of 56 volatile compounds were revealed and identified in oil extracted by SFE, while only 40 compounds were detected in extracted oil by SPP. Acids, aldehydes, esters, ketones, furans, and other components were present in the highest ratio in oil extracted by SFE. In contrast, alcs. and alkenes were found in the highest proportion in oil extracted by SPP. In this study, it was observed that SFE showed an increase in the amounts of volatile compounds and favorably impacted the aroma of gurum seed oil. The results reveal that different extraction methods significantly impact the volatile components of gurum seed oil, and this study can help evaluate the quality of the oil extracted from gurum seeds.

111-90-0, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., Recommanded Product: Diethylene Glycol Monoethyl Ether

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. 111-90-0, formula is C6H14O3, Name is Diethylene Glycol Monoethyl Ether. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3. Recommanded Product: Diethylene Glycol Monoethyl Ether.

Kassaee, Seyedeh Negin;Mahboobian, Mohammad Mehdi research published 《 Besifloxacin-loaded ocular nanoemulsions: design, formulation and efficacy evaluation》, the research content is summarized as follows. The purpose of this study was to develop and evaluate nanoemulsions (NEs) containing besifloxacin for ocular drug delivery. Pseudo ternary phase diagrams were constructed using Triacetin (oil), Cremophor RH 40 (surfactant), and Transcutol^P (co-surfactant) to identify NE regions. Six formulations were developed by low-energy emulsification method and then evaluated for size, refractive index, pH, osmolality, viscosity, and drug release. After accelerated phys. stability and bovine conrneal permeation studies, NE2 was chosen as optimized formulation forantimicrobial efficacy, and hens egg test-chorioallantoic membrane (HET-CAM) tests. The particle size of optimum NE was 14 nm with a narrow size distribution. Moreover, other physicochem. characterizations were in the acceptable range for ocular administration. Besifloxacin-loaded NEs demonstrated sustained release pattern and 1.7-fold higher permeation compared with the control suspension in the ex vivo transcorneal permeation study. HET-CAM test indicated no irritation, and HL% revealed no damage to the tissue, so the optimum NE is well tolerated by the eye. In vitro antimicrobial evaluation, showed comparative efficacy of lower drug-loaded NE (0.2%) vs. 0.6% besifloxacin suspension (equal concentration to com. besifloxacin eye drop). In conclusion, besifloxacin-loaded NEs could be considered as a suitable alternative to the marketed suspension for treating bacterial eyeinfections.

111-90-0, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., Recommanded Product: Diethylene Glycol Monoethyl Ether

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers do have nonbonding electron pairs on their oxygen atoms, 111-90-0, formula is C6H14O3, Name is Diethylene Glycol Monoethyl Ether. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds. Reference of 111-90-0.

Kataoka, Taishi;Orita, Yasuhiko;Shimoyama, Yusuke research published 《 CO₂ absorption and desorption using phase-separation gel》, the research content is summarized as follows. Phase-separation absorbent has attracted much attention to reduce energy consumption for CO₂ capture, storage and utilization. In this work, to improve handling of the absorbents, we have developed a new semi-solid absorbent, phase-separation gel, which became clouded gel by CO₂ absorption and returned to transparent by CO₂ desorption. We measured amounts of CO₂ absorption at 50 C and desorption at 90 C with 10 vol% CO₂ gas mixed with N₂ gas. A cyclic capacity defined by the CO₂ desorption amount of a phase-separation gel with solvent of 2-(ethylamino)ethanol/diethylene glycol di-Et ether was larger than those of the other homogeneous gels with 2-(ethylamino)ethanol/diethylene glycol monoethyl ether or diethylene glycol. Furthermore, the initial desorption flux of the phase-separation gel was larger than that of the absorbent solvent, suggesting that the phase-separation absorbent fixed inside the gels improves the initial desorption flux because of the larger interfacial area between the CO₂-rich and CO₂-lean phases inside the gel.

111-90-0, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., Reference of 111-90-0

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers do have nonbonding electron pairs on their oxygen atoms, 111-90-0, formula is C6H14O3, Name is Diethylene Glycol Monoethyl Ether. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds. Category: ethers-buliding-blocks.

Humes, Mackenzie B.;Wang, Mingyi;Kim, Sunhye;Machesky, Jo E.;Gentner, Drew R.;Robinson, Allen L.;Donahue, Neil M.;Presto, Albert A. research published 《 Limited Secondary Organic Aerosol Production from Acyclic Oxygenated Volatile Chemical Products》, the research content is summarized as follows. Volatile chem. products (VCPs) have recently been identified as potentially important unconventional sources of secondary organic aerosol (SOA), in part due to the mitigation of conventional emissions such as vehicle exhaust. Here, we report measurements of SOA production in an oxidation flow reactor from a series of common VCPs containing oxygenated functional groups and at least one oxygen within the mol. backbone. These include two oxygenated aromatic species (phenoxyethanol and 1-phenoxy-2-propanol), two esters (Bu butyrate and Bu acetate), and four glycol ethers (carbitol, Methyl Carbitol, Butyl Carbitol, and hexyl carbitol). We measured gas- and particle-phase products with a suite of mass spectrometers and particle-sizing instruments. Only the aromatic VCPs produce SOA with substantial yields. For the acyclic VCPs, ether and ester functionality promotes fragmentation and hinders autoxidation, whereas aromatic rings drive SOA formation in spite of the presence of ether groups. Therefore, our results suggest that a potential strategy to reduce urban SOA from VCPs would be to reformulate consumer products to include less oxygenated aromatic compounds

Category: ethers-buliding-blocks, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., 111-90-0.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers lack the hydroxyl groups of alcohols. Without the strongly polarized O―H bond, ether molecules cannot engage in hydrogen bonding with each other. 111-90-0, formula is C6H14O3, Name is Diethylene Glycol Monoethyl Ether. Ethers do have nonbonding electron pairs on their oxygen atoms, however, and they can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. Product Details of C6H14O3.

Hussain, Afzal;Afzal, Obaid;Altamimi, Abdulmalik S. A.;Ali, Raisuddin research published 《 Application of green nanoemulsion to treat contaminated water (bulk aqueous solution) with azithromycin》, the research content is summarized as follows. The present work aimed to remove azithromycin (AZM) from the contaminated aqueous system using a water/ethanol/transcutol/Capryol-90 green nanoemulsion. The drug is identified as a potential pharmaceutical contaminant detrimental for flora and fauna of aquatic lives as well as human health. Green nanoemulsions were tailored and characterized for thermodn. stability, size, polydispersity index (PDI), zeta potential, viscosity, refractive index (RI), and morphol. assessment using a transmission electron microscopy (TEM). Moreover, nanoemulsions were investigated for percent removal efficiency (%RE) and factors affecting percent removal efficiency (%RE). The results suggested that the developed green nanoemulsions (ANE1-ANE5) were transparent (200 nm) and stable. ANE5 exhibited the lowest value of globular size (49 nm), PDI (0.17), viscosity (∼ 93 cP), and optimum zeta potential (-27.8 mV). The value of %RE depended upon the content of water and Capryol-90 of the nanoemulsion. Furthermore, the value of %RE was found to be increased with increased content of water, whereas this was decreased on increasing the Capryol-90 content in the nanoemulsions. Similarly, on decreasing the values of size and viscosity, the %RE values were observed to be increased. There was insignificant impact of the duration of exposure time on %RE. Thus, the maximum %RE value (96.8%) was obtained by ANE5 from the aqueous solution after 20 min of contact time with ANE5. Thus, this method could be a promising approach to remove AZM from the contaminated water and serve as an alternative to conventional methods.

Product Details of C6H14O3, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., 111-90-0.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers can again be classified into two varieties: if the alkyl or aryl groups are the same on both sides of the oxygen atom, 111-90-0, formula is C6H14O3, Name is Diethylene Glycol Monoethyl Ether. Then it is a simple or symmetrical ether, whereas if they are different, the ethers are called mixed or unsymmetrical ethers. Product Details of C6H14O3.

Hussain, Afzal;Alshehri, Sultan;Ramzan, Mohhammad;Afzal, Obaid;Altamimi, Abdulmalik S. A.;Alossaimi, Manal A. research published 《 Biocompatible solvent selection based on thermodynamic and computational solubility models, in-silico GastroPlus prediction, and cellular studies of ketoconazole for subcutaneous delivery》, the research content is summarized as follows. We aimed to identify a suitable solvent [dimethyl acetamide (DMA), Et acetate, (EA), N-Me pyrrolidone (NMP), cremophor-EL (CEL), transcutol-HP (THP), polyethylene glycol 400 (PEG-400), limonene and ethanol] based on exptl. solubility, thermodn./computational parameters for s.c. (sub-Q) delivery. The “van′t Hoff” model validated solubility values in several solvents at “T = 298.2 K-318.2 K” and “p = 0.1 MPa”. In silico prediction study was carried out for sub-Q delivery using GastroPlus. The selected KETO-DMA construct was evaluated for cellular interaction, cellular uptake (L929 cells), cytotoxicity (L929 and J774A.1) and antifungal activities (C. albicans, C. glabrata, C. Tropicalis, and A. niger). The maximum mole fractional solubility of KETO were found in three solvents such as DMA (4.8 x 10^-2) EA (2.8 x 10^-2) NMP (11.7 x 10^-3) at “T = 318.2 K”. Anal. confirmed “endothermic and entropy” driven solubilization process. GastroPlus predicted pharmacokinetics parameters were influenced with nonsaturable metabolic clearance in s.c. tissue of human. Interaction study of KETO-DMA solution with Candida cells showed maximized cellular internalization. KETO-DMA solution exhibited poor cellular uptake by L929 cell lines (murine fibroblast cells) compared to KETO aqueous solution which was further supported with cytotoxicity study in L929 and J774A.1 cell lines. Reduced MIC values of KETO-DMA solution as compared to KETO aqueous solution against four strains corroborated improved efficacy of KETO probably due to augmented solubility in DMA and lack of surfactant. Thus, KETO-DMA solution can be a suitable construct for sub-Q delivery to control fungal infections.

Product Details of C6H14O3, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., 111-90-0.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers do have nonbonding electron pairs on their oxygen atoms, 111-90-0, formula is C6H14O3, Name is Diethylene Glycol Monoethyl Ether. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds. Reference of 111-90-0.

Iqubal, Mohammad Kashif;Iqubal, Ashif;Imtiyaz, Khalid;Rizvi, M. Moshahid A.;Gupta, Madan Mohan;Ali, Javed;Baboota, Sanjula research published 《 Combinatorial lipid-nanosystem for dermal delivery of 5-fluorouracil and resveratrol against skin cancer: Delineation of improved dermatokinetics and epidermal drug deposition enhancement analysis》, the research content is summarized as follows. In the present study, combinatorial nanostructured lipid carrier gel of 5-fluorouracil and resveratrol was formulated, optimized and characterized to enhance permeation in between epidermis and dermis layers of the skin to obtain a synergistic effect against skin cancer. After extensive trials, a newly modified emulsiosonication method was developed and addnl., for the first time, stability studies were done in the beginning to optimize formulation technique, which exhibited two major benefits simultaneously; first, it provided best-optimized technique for preparation of combinatorial lipid-nanosystem, and secondly, it also demonstrated a detailed report card of durability of formulations. In vitro release study showed a significantly improved, slow and prolonged release of drugs from the optimized lipid-nanosystem (***p < 0.05), which followed non-Fickian Higuchi kinetics. Besides, mechanism of skin permeation enhancement study, dermatokinetic assessment, and depth anal. of optimized formulation on skin exhibited improved permeation and well distribution of drugs up to the dermis layer of skin. Moreover, combinatorial linogel possessed significantly greater efficacy (**p < 0.01) on the A431 cell line, as compared to the conventional formulation. Thus, findings revealed that modified method of preparation for dual drug-loaded lipid-nanosystem lead to the production of a stable formulation that also improved the retention of both 5-fluorouracil and resveratrol in between the epidermis and dermis region of skin thereby helping in the management and treatment of skin cancer.

111-90-0, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., Reference of 111-90-0

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers are a class of organic compounds that contain an ether group—an oxygen atom connected to two alkyl or aryl groups. 111-90-0, formula is C6H14O3, Name is Diethylene Glycol Monoethyl Ether.They have the general formula R–O–R′, where R and R′ represent the alkyl or aryl groups. Formula: C6H14O3.

Jurca, Tuende;Pallag, Annamaria;Vicas, Laura;Marian, Eleonora;Muresan, Mariana;Ujhelyi, Zoltan;Feher, Palma;Bacskay, Ildiko research published 《 Formulation and antioxidant investigation of creams containing Robinia pseudoacacia flos L. ethanolic extract》, the research content is summarized as follows. Some vegetable products can be incorporated into skin care products in order to treat conditions such as skin dryness and can function as an antioxidant. Creams were formulated with Robinia pseudoacacia flos extracts This study was aimed to investigate the antioxidant activity of the cthanolic extracts and the obtained creams. The fractions of Robinia pseudoacacia flos were found to be rich sources of polyphenols with marked antioxidant activity, evidenced by the DPPH method. The phenolic acids, identified by HPLC-RP with UV detection, were gallic acid, sinapic acid, caffeic acid and vanillic acid and the predominant flavonoids were quercetin, rutin and lutcolin. The extract was previously dissolved in Transcutol and then mixed in the same oil/water (O/W) base containing Sucrose ester SP50, Tefose 63, Sedefos 75 as emulsifiers. The in vitro release of different compounds was evaluated by the Franz diffusion method. The creams containing Robiniae pseudacaciae flos extract exhibited large amounts of diffused substances. Antioxidant activity was determined by the DPPH (1,1-diphenyl-2-pycrylhydrazyl) method, according to the methodol. described by Brand-Williams.

Formula: C6H14O3, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., 111-90-0.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem