Tag: M.W=100-150

Beke, Ferenc; Meszaros, Adam; Toth, Agnes; Botlik, Bence Bela; Novak, Zoltan published the artcile< Vicinal difunctionalization of carbon-carbon double bond for the platform synthesis of trifluoroalkyl amines>, Application In Synthesis of 10541-78-3, the main research area is trifluoroalkyl amine preparation regioselective; amine trifluoroalkenyl iodonium salt three component diamination.

Herein, the controllable double nucleophilic functionalization of an activated alkene synthon I, originated from a trifluoropropenyliodonium salt with two distinct nucleophiles, enables the selective synthesis of trifluoromethylated ethylene amines and diamines RCH(CF3)CH2R1 (R = methyl(naphthalen-1-ylmethyl)aminyl, methyl(prop-2-yn-1-yl)aminyl, 3-azabicyclo[3.2.2]nonan-3-yl, etc.; R1 = {1-[(tert-butoxy)carbonyl]azetidin-3-yl}(2-phenylethyl)aminyl, 2-sulfanylidene-1,2-dihydropyridin-1-yl, etc.) on broad scale with high efficiency under mild reaction conditions. Considering the chem. nature of the reactants, this synthetic approach brings forth an efficient methodol. and provides versatile access to highly fluorinated amines.

Nature Communications published new progress about Amination, regioselective. 10541-78-3 belongs to class ethers-buliding-blocks, and the molecular formula is C8H11NO, Application In Synthesis of 10541-78-3.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Chen, Hui; Niu, Zhihui; Ye, Jing; Zhang, Changkun; Zhang, Xiaohong; Zhao, Yu published the artcile< Multicore Ferrocene Derivative as a Highly Soluble Cathode Material for Nonaqueous Redox Flow Batteries>, Application In Synthesis of 6482-24-2, the main research area is redox flow battery ferrocene derivative cathode.

Nonaqueous redox flow batteries (NARFBs) are considered promising electrochem. energy storage systems to overcome the limited electrochem. window of aqueous counterparts. However, the limited solubility of redox-active materials in the nonaqueous phase, for instance, the intensively investigated ferrocene derivatives, needs to be addressed prior to their practical implementation. In this study, we demonstrate the design and synthesis of a multicore ferrocene derivative, 4,4-diferrocenyl-1-(2-methoxy-ethoxy)-pentane (DFDE), as a highly soluble cathode-active material for NARFBs. Owing to the tailored ether chain as well as the synergistic effect of multiple ferrocene cores, DFDE exhibits a high solubility of 4.5 M equivalent electron concentration in an ether-based solvent as well as a more pos. redox potential compared with pristine ferrocene, which are essential to improve the energy d. of NARFBs. Moreover, electrochem. characterizations reveal that DFDE undergoes highly reversible redox reactions with a fast electron-transfer rate constant When paired with N-butyl-phthalimide (BuPh), the cell exhibits a discharge voltage of ca. 1.8 V and stable cycling performance. The use of multicore ferrocene derivatives might represent an effective yet to be explored strategy to overcome the solubility limit of ferrocene-based cathode materials at affordable environmental and ecol. load.

ACS Applied Energy Materials published new progress about Battery cathodes. 6482-24-2 belongs to class ethers-buliding-blocks, and the molecular formula is C3H7BrO, Application In Synthesis of 6482-24-2.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Li, Kangkang; Li, Jin-Feng; Yin, Bing; Zeng, Fanlong published the artcile< Investigation of NNN Pincer Ruthenium(II) Complexes with a Pendant Hydroxyl Group for N-Monomethylation of amines and Nitroarenes by Methanol>, Application In Synthesis of 10541-78-3, the main research area is hydroxy trinitrogen NNN pincer ruthenium preparation crystal mol structure; monomethylation amine nitroarene methanol hydroxy trinitrogen pincer ruthenium catalyzed.

A family of air- and moisture-stable NNN pincer ruthenium(II) complexes with a pendant OH were developed, which exhibit unprecedented high reactivity and selectivity in N-monomethylation of amines and nitroarenes using methanol. The study reveals adopting the combination of 1H-pyrazole-1-yl and 3,5-dimethyl-4-hydroxyethyl-1H-pyrazol-1-yl as the two assistant arms of the pyridyl-backbone is a suitable choice. The mechanism study discloses that, during the catalytic cycle, dehydrogenation of methanol to form formaldehyde is a fast and reversible step.

ChemCatChem published new progress about Amines Role: RCT (Reactant), RACT (Reactant or Reagent). 10541-78-3 belongs to class ethers-buliding-blocks, and the molecular formula is C8H11NO, Application In Synthesis of 10541-78-3.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Huang, Shuang; Hong, Xi; Cui, He-Zhen; Zhou, Quan; Lin, Yue-Jian; Hou, Xiu-Feng published the artcile< N-Methylation of ortho-substituted aromatic amines with methanol catalyzed by 2-arylbenzo[d]oxazole NHC-Ir(III) complexes>, Related Products of 10541-78-3, the main research area is arylamine methanol arylbenzoxazole iridium complex catalyst methylation green chem; methyl arylamine preparation.

Seven new chelated cyclometalated Ir complexes of ABON,P, ABON,O and ABON,C(carbene) based on a rigid and tunable 2-arylbenzo[d]oxazole backbone were prepared for the N-methylation of amines. Among these three coordinated modes, ABON,C(carbene)-chelated iridium-based catalysts exhibited good performance in the monomethylation of aromatic amines with methanol (MeOH) as the green methylation reagent. The steric-modified synthesis of ABON,C(carbene) complexes was described. The most active ABON,C(carbene) complex with marginal steric hindrance as a catalyst was obtained from the benzoxazole ring without a substituent and Me group of the benzimidazole ring on the N-heterocyclic carbene (NHC) ligand. A variety of amines including para- and meta-substituted aromatic amines, as well as heterocyclic amines, were formulated as suitable substrates. Importantly, this catalyst considerably promoted the yield of the N-methylation of ortho-substituted aromatic amines. Controlled kinetic experiments and deuterium-labeling reactions of these ortho-substituted amines were conducted under optimized conditions. On the basis of the exptl. results, a plausible mechanism was proposed.

Dalton Transactions published new progress about Benzoxazoles Role: CAT (Catalyst Use), PRP (Properties), RCT (Reactant), SPN (Synthetic Preparation), USES (Uses), RACT (Reactant or Reagent), PREP (Preparation). 10541-78-3 belongs to class ethers-buliding-blocks, and the molecular formula is C8H11NO, Related Products of 10541-78-3.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Beke, Ferenc; Meszaros, Adam; Toth, Agnes; Botlik, Bence Bela; Novak, Zoltan published the artcile< Vicinal difunctionalization of carbon-carbon double bond for the platform synthesis of trifluoroalkyl amines>, Application In Synthesis of 10541-78-3, the main research area is trifluoroalkyl amine preparation regioselective; amine trifluoroalkenyl iodonium salt three component diamination.

Herein, the controllable double nucleophilic functionalization of an activated alkene synthon I, originated from a trifluoropropenyliodonium salt with two distinct nucleophiles, enables the selective synthesis of trifluoromethylated ethylene amines and diamines RCH(CF3)CH2R1 (R = methyl(naphthalen-1-ylmethyl)aminyl, methyl(prop-2-yn-1-yl)aminyl, 3-azabicyclo[3.2.2]nonan-3-yl, etc.; R1 = {1-[(tert-butoxy)carbonyl]azetidin-3-yl}(2-phenylethyl)aminyl, 2-sulfanylidene-1,2-dihydropyridin-1-yl, etc.) on broad scale with high efficiency under mild reaction conditions. Considering the chem. nature of the reactants, this synthetic approach brings forth an efficient methodol. and provides versatile access to highly fluorinated amines.

Nature Communications published new progress about Amination, regioselective. 10541-78-3 belongs to class ethers-buliding-blocks, and the molecular formula is C8H11NO, Application In Synthesis of 10541-78-3.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Liu, Wei; Lavagnino, Marissa N.; Gould, Colin A.; Alcazar, Jesus; MacMillan, David W. C. published the artcile< A biomimetic SH2 cross-coupling mechanism for quaternary sp3-carbon formation>, Related Products of 6482-24-2, the main research area is ester alkyl bromide photoredox cross coupling iron.

Bimol. homolytic substitution (SH2) is an open-shell mechanism that is implicated across a host of biochem. alkylation pathways. Surprisingly, however, this radical substitution manifold has not been generally deployed as a design element in synthetic C-C bond formation. Authors found that the SH2 mechanism can be leveraged to enable a biomimetic sp3-sp3 cross-coupling platform that furnishes quaternary sp3-carbon centers, a long-standing challenge in organic mol. construction. This heteroselective radical-radical coupling uses the capacity of iron porphyrin to readily distinguish between the SH2 bond-forming roles of open-shell primary and tertiary carbons, combined with photocatalysis to generate both radical classes simultaneously from widely abundant functional groups. Mechanistic studies confirm the intermediacy of a primary alkyl-Fe(III) species prior to coupling and provide evidence for the SH2 displacement pathway in the critical quaternary sp3-carbon bond formation step.

Science (Washington, DC, United States) published new progress about Bromoalkanes Role: RCT (Reactant), RACT (Reactant or Reagent). 6482-24-2 belongs to class ethers-buliding-blocks, and the molecular formula is C3H7BrO, Related Products of 6482-24-2.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Wang, Shihaozhi; Yang, Jiale; Li, Dianjun; Yang, Jinhui published the artcile< Copper-Catalyzed Cascade N-Dealkylation/N-Methyl Oxidation of Aromatic Amines by Using TEMPO and Oxygen as Oxidants>, Name: 2-Methoxy-N-methylaniline, the main research area is aryl formamide preparation; amine aryl cascade dealkylation oxidation catalyst copper.

A novel tandem N-dealkylation and N-Me aerobic oxidation of tertiary aromatic amines to N-arylformamides ArNC(O)H [Ar = Ph, 4-MeC6H4, 3-MeOC6H4, etc.] using copper and TEMPO was developed. This methodol. suggested an alternative synthetic route from N-methylarylamines to N-arylformamides ArNC(O)H.

European Journal of Organic Chemistry published new progress about Amines Role: RCT (Reactant), RACT (Reactant or Reagent). 10541-78-3 belongs to class ethers-buliding-blocks, and the molecular formula is C8H11NO, Name: 2-Methoxy-N-methylaniline.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Dobah, Farhaan; Mazodze, C. Munashe; Petersen, Wade F. published the artcile< Cross-Dehydrogenative Cyclization-Dimerization Cascade Sequence for the Synthesis of Symmetrical 3,3'-Bisoxindoles>, Category: ethers-buliding-blocks, the main research area is bisoxindole preparation; oxoalkyl anilide preparation manganese tandem oxidative radical cyclization dimerization.

The synthesis of sym. 3,3′-bisoxindoles from simple acyclic β-oxoanilides were reported. The described method forged three new C-C bonds in a single step via a sequential Mn(OAc)3·2H2O mediated oxidative radical cyclization-fragmentation-dimerization process. The scope of this reaction was demonstrated in the preparation of a variety of 3,3′-bisoxindoles, as well as its application toward the formal synthesis of the Calycanthaceae alkaloid, (±)-folicanthine.

Organic Letters published new progress about Acid chlorides Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 10541-78-3 belongs to class ethers-buliding-blocks, and the molecular formula is C8H11NO, Category: ethers-buliding-blocks.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Zhao, Wenfeng; Chi, Xiaoping; Li, Hu; He, Jian; Long, Jingxuan; Xu, Yufei; Yang, Song published the artcile< Eco-friendly acetylcholine-carboxylate bio-ionic liquids for controllable N-methylation and N-formylation using ambient CO2 at low temperatures>, Synthetic Route of 10541-78-3, the main research area is ecofriendly acetylcholine carboxylate bio ionic liquid catalyst methylation formylation; carbon dioxide formylation methylation ionic liquid catalyst.

Catalytic fixation of CO2 to produce valuable fine chems. is of great significance to develop a green and sustainable circulation of excessive carbon in the environment. Herein, a series of nontoxic, biodegradable and recyclable acetylcholine-carboxylate bio-ionic liquids with different cations and anions were simply synthesized for producing formamides and methylamines using atm. CO2 as a carbon source, and phenylsilane as a hydrogen donor. The selectivity toward products was tuned by altering the reaction temperature under solvent or solvent-free conditions. N-Methylamines (ca. 96% yield) were obtained in acetonitrile at 50 °C, while N-formamides (ca. 99% yield) were attained without a solvent at 30 °C. The established bio-ionic liquid catalytic system found a wide range of applicability in substrates and possessed a high potentiality in scale-up to gram-grade production The developed catalytic system was fairly stable, which could be easily reused without an apparent loss of reactivity, possibly due to the strong electrostatic interactions between the cation and anion. The combination of exptl. and computational results explicitly elucidated the reaction mechanism: PhSiH3 activated by a bio-IL was favorable for the formation of silyl formate from hydrosilylation of CO2, followed by a reaction with an amine to give an N-formamide, while an N-methylamine was formed by further hydrosilylation of the N-formamide.

Green Chemistry published new progress about Biodegradable materials. 10541-78-3 belongs to class ethers-buliding-blocks, and the molecular formula is C8H11NO, Synthetic Route of 10541-78-3.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ahn, Seongmo; Jang, Jin Hyeok; Kang, Jungtaek; Na, Moony; Seo, Jia; Singh, Vikram; Joo, Jung Min; Byon, Hye Ryung published the artcile< Systematic Designs of Dicationic Heteroarylpyridiniums as Negolytes for Nonaqueous Redox Flow Batteries>, COA of Formula: C3H7BrO, the main research area is systematic designs dicationic heteroarylpyridiniums negolytes nonaqueous redox flow battery.

Many organic redox materials are chem. unstable and sparingly soluble in nonaqueous media. Addnl., the crossover of redox materials and the availability of limited membranes have restricted the examination of the long-term cyclability of these materials in nonaqueous redox flow batteries (RFBs). To overcome these limitations, we developed a new class of pyridinium-based negolytes. The π-conjugation structure of the pyridinium mols. was extended by introducing benzothiazole into the C4-position of pyridinium, which improved the stability of these mols. Cationic ammonium functional groups at the N-substituent suppressed the crossover of the pyridinium negolytes through an anion exchange membrane. Furthermore, the solubility of the negolyte was increased up to ~1 M in acetonitrile and 0.3-0.5 M with tetrabutylammonium bis(trifluoromethanesulfonyl)imide (TBATFSI) and acetonitrile. A 0.1 M solution of the dicationic benzothiazolylpyridinium exhibited 0.0083% capacity-fading rate per cycle in sym. RFBs for 250 cycles and 0.08% in full RFBs comprising the ammonium-substituted ferrocene as a posolyte for 500 cycles.

ACS Energy Letters published new progress about Anion exchange membranes. 6482-24-2 belongs to class ethers-buliding-blocks, and the molecular formula is C3H7BrO, COA of Formula: C3H7BrO.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem