Tag: 300-400

Extraction of curcumin from Curcuma longa using meglumine and pyroglutamic acid, respectively, as solubilizer and hydrotrope was written by Degot, Pierre;Funkner, Diana;Huber, Verena;Koeglmaier, Moritz;Touraud, Didier;Kunz, Werner. And the article was included in Journal of Molecular Liquids in 2021.Application of 33171-05-0 The following contents are mentioned in the article:

In preceding papers, it could be shown that mixtures of water, ethanol, and triacetin can significantly boost the extraction of curcuminoids out of Curcuma longa, compared to the usually applied water-ethanol mixtures To further improve it, additives can be beneficial. We show that meglumine and pyroglutamic acid are among the most promising of these additives. First, the influence of meglumine and pyroglutamic acid on the phase diagram of ternary mixtures consisting of water, ethanol and triacetin has been investigated: the addition of meglumine to the water phase only slightly increases the miscibility gap, whereas pyroglutamic acid increases it significantly in the oil-rich region. The solubility of curcumin could be significantly enhanced through the addition of meglumine. Extractions were successfully conducted extracting ∼18 mg of curcuminoids per g Curcuma longa by adding 15 wt% of meglumine to the amount of water in the extraction mixtures consisting of water, ethanol and triacetin, which is an increase of ∼ 20% compared to the best extraction mixture water/ethanol/triacetin from the previous study. A simple water/meglumine extraction was also investigated. Around 13 mg curcuminoids per g Curcuma longa could be extracted Bisdemethoxycurcumin contributes 3.46 mg to the total amount, which is a very good extraction yield (increase of 19% compared to the best extraction mixture from the previous study). The purity of the extract reached 87% just by extracting with water and meglumine. For comparison, the same purity was achieved using the ternary water/ethanol/triacetin system, but only after freeze drying of the rhizomes before extraction This study involved multiple reactions and reactants, such as Bisdemethoxycurcumin (cas: 33171-05-0Application of 33171-05-0).

Bisdemethoxycurcumin (cas: 33171-05-0) belongs to ethers. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Application of 33171-05-0

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Bisdemethoxycurcumin Induces Cell Apoptosis and Inhibits Human Brain Glioblastoma GBM 8401/Luc2 Cell Xenograft Tumor in Subcutaneous Nude Mice In Vivo was written by Hsia, Te-Chun;Peng, Shu-Fen;Chueh, Fu-Shin;Lu, Kung-Wen;Yang, Jiun-Long;Huang, An-Cheng;Hsu, Fei-Ting;Wu, Rick Sai-Chuen. And the article was included in International Journal of Molecular Sciences in 2022.Synthetic Route of C19H16O4 The following contents are mentioned in the article:

Bisdemethoxycurcumin (BDMC) has biol. activities, including anticancer effects in vitro; however, its anticancer effects in human glioblastoma (GBM) cells have not been examined yet. This study aimed to evaluate the tumor inhibitory effect and mol. mechanism of BDMC on human GBM 8401/luc2 cells in vitro and in vivo. In vitro studies have shown that BDMC significantly reduced cell viability and induced cell apoptosis in GBM 8401/luc2 cells. Furthermore, BDMC induced apoptosis via inhibited Bcl-2 (anti-apoptotic protein) and increased Bax (pro-apoptotic proteins) and cytochrome c release in GBM 8401/luc2 cells in vitro. Then, twelve BALB/c-nude mice were xenografted with human glioblastoma GBM 8401/luc2 cancer cells s.c., and the xenograft nude mice were treated without and with BDMC (30 and 60 mg/kg of BDMC treatment) every 3 days. GBM 8401/luc2 cell xenografts experiment showed that the growth of the tumors was significantly suppressed by BDMC administration at both doses based on the reduction of tumor size and weights BDMC did not change the body weight and the H&E histopathol. anal. of liver samples, indicating that BDMC did not induce systemic toxicity. Meanwhile, treatment with BDMC up-regulated the expressions of BAX and cleaved caspase-3, while it down-regulated the protein expressions of Bcl-2 and XIAP in the tumor tissues compared with the control group. This study has demonstrated that BDMC presents potent anticancer activity on the human glioblastoma GBM 8401/luc2 cell xenograft model by inducing apoptosis and inhibiting tumor cell proliferation and shows the potential for further development to the anti-GBM cancer drug. This study involved multiple reactions and reactants, such as Bisdemethoxycurcumin (cas: 33171-05-0Synthetic Route of C19H16O4).

Bisdemethoxycurcumin (cas: 33171-05-0) belongs to ethers. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Synthetic Route of C19H16O4

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

HPLC fingerprint and UV-Vis spectroscopy coupled with chemometrics for Curcumae radix species discrimination and three bioactive compounds prediction was written by Wang, Le;Ren, Xueyang;Wang, Yu;Liu, Xiaoyun;Dong, Ying;Ma, Jiamu;Song, Ruolan;Yu, AXiang;Wei, Jing;Fan, Qiqi;Wang, Xiuhuan;She, Gaimei. And the article was included in Microchemical Journal in 2021.Electric Literature of C19H16O4 The following contents are mentioned in the article:

Curcumae Radix with four botanical origins (Wenyujin, Huangyujin, Guiyujin, Lvyujin) has a long medical history in China. The four species have not been differentiated well in clin. application, though there were differences in pharmacol. effects among them. For the aim of fast discrimination and quant. anal. of Yujin, HPLC (high performance liquid chromatog.) fingerprint and UV-Vis (UV-visible) spectroscopy technologies coupled with chemometrics were employed. The HPLC fingerprints of 26 Guiyujin, 11 Huangyujin, 11 Lvyujin, 29 Wenyujin and full 77 samples were sep. established, with good similarities among same species except Wenyujin and poor consistence in full samples. UV-Vis spectra showed obvious three absorption peaks in the spectra of Huangyujin samples and only one in that of the rest samples. LDA (linear discriminant anal.) and Bagged Trees models established based on HPLC fingerprint data attained higher than 90% discrimination accuracy. Based on the spectral data, complete separation for the four species of Yujin was failed to achieve by PCA (principal component anal.), and the KNN (k-nearest neighbors) and SVM (support vector machine) models achieved no<90% discrimination accuracies. Furthermore, the SVMR (support vector machine regression) and Bagged Trees Regression models used to quickly predict the contents of germacrone, curcumenol and curdione performed well, with relatively lower RMSE (root mean square error) and higher R² (coefficient of determination) values. The present study proposed relatively rapid methods for the determination of bioactive compounds and discrimination of Yujin. This study involved multiple reactions and reactants, such as Bisdemethoxycurcumin (cas: 33171-05-0Electric Literature of C19H16O4).

Bisdemethoxycurcumin (cas: 33171-05-0) belongs to ethers. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Electric Literature of C19H16O4

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Downregulation of miR-21 gene expression by CRE-Ter to modulate osteoclastogenesis: De Novo mechanism was written by Pengjam, Yutthana;Prajantasen, Thanet;Tonwong, Natda;Panichayupakaranant, Pharkphoom. And the article was included in Biochemistry and Biophysics Reports in 2021.Recommanded Product: 33171-05-0 The following contents are mentioned in the article:

MiR-21 expression stimulates osteoclast cells in the context of osteoclastogenesis. A previous report showed that NFκB-miR-21 pathway could serve as an innovative alternative to devise therapeutics for healing diabetic ulcers. Furthermore, our study demonstrated that a highly water-soluble curcuminoids-rich extract (CRE-Ter) inhibits osteoclastogenesis through NFκB pathway. The interplay between miR-21 and CRE-Ter in osteoclastogenesis has not yet been investigated. In this study, we examined the relation of CRE-Ter and miR-21 gene expression in receptor of the nuclear factor κB (NFκB) ligand (RANKL) – induced murine monocyte/macrophage RAW 264.7 cells, osteoclast cells, in osteoclastogenesis. Effect of CRE-Ter on generation of intracellular reactive oxygen species (ROS) was estimated by dichlorofluorescein diacetate (DCFH-DA). The results reveal that CRE-Ter reduced expression levels of miR-21 gene in osteoclasts. The inhibitory effects of CRE-Ter on in vitro osteoclastogenesis were evaluated by reduction in tartrate-resistant acid phosphatase (TRAP) content, and by reduction in expression levels of an osteoclast-specific gene, cathepsin K. Treatment of the osteoclast cells with CRE-Ter suppressed RANKL-induced NFκB activation including phospho-NFκB-p65, and phospho IκBα proteins. Western blot anal. revealed that NFκB inhibitor up-regulated CRE-Ter-promoted expression of phospho-NFκB-p65. In addition, CRE-Ter dose-dependently inhibited phospho-Akt expression. CRE-Ter also dose-dependently reduced DNA binding activity of NFκB and Akt as revealed by EMSA. ChIP assay revealed binding of NFκB-p65 to miR-21 promoters. In conclusion, our results demonstrate that CRE-Ter downregulates miR-21 gene expression in osteoclasts via a de novo mechanism, NFκB-Akt-miR-21 pathway. This study involved multiple reactions and reactants, such as Bisdemethoxycurcumin (cas: 33171-05-0Recommanded Product: 33171-05-0).

Bisdemethoxycurcumin (cas: 33171-05-0) belongs to ethers. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Recommanded Product: 33171-05-0

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Distinct metabolomes and quality characteristics of vacuum-assisted osmosonic-pretreated Curcuma longa L. rhizomes subjected to different drying methods was written by Alolga, Raphael N.;Osae, Richard;Ibrahim, Traore S.;Onoja, Vitus;Apaliya, Maurice T.;Kwaw, Emmanuel;Huang, Feng-Qing. And the article was included in Industrial Crops and Products in 2022.Reference of 33171-05-0 The following contents are mentioned in the article:

This study sought to investigate the impact of four drying methods, thus, sun (S) drying, freeze (F) drying, relative humidity convective (RHC) drying and IR (IR) drying, on the metabolomes and quality characteristics of vacuum-assisted osmosonic-pretreated turmeric (Curcuma longa L.) slices. The quality characteristics examined included contents of marker compounds, antioxidant activities, total phenolic content (TPC), total flavonoid content (TFC), chromatic properties, sensory characteristics, rehydration ratios (RR), and moisture diffusivities. Using LC-Q/TOF-MS and chemometric analyses, the metabolomes of variously dried turmeric samples were examined In this regard, we found distinct metabolome differences between the samples. These differences translated into differential levels of three marker compounds, thus, curcumin, demethoxycurcumin and bisdemethoxycurcumin as captured by HPLC-DAD anal. Overall, F drying gave the best results for all parameters assessed except for effective moisture diffusivity. Specifically, the F dried samples possessed the highest contents of the marker compounds, curcumin (3.99 ± 0.01μg/mg), BDMC (0.275 ± 0.0006μg/mg), DMC (0.170 ± 0.0007μg/mg). The F dried samples also possessed the highest antioxidant activities, TPC, and TFC, chromatic and sensory characteristics. There were also marked differences in the rehydration ratios (RR), and the moisture diffusivities of the various dried samples. The RHC dried samples ranked second to the F dried samples for all quality parameters examined In summary, for all the quality characteristics examined, the following order in terms of suitability and potential industrial large-scale applicability of the various drying methods was deduced: F drying > RHC drying > IR drying > S drying. This study involved multiple reactions and reactants, such as Bisdemethoxycurcumin (cas: 33171-05-0Reference of 33171-05-0).

Bisdemethoxycurcumin (cas: 33171-05-0) belongs to ethers. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Reference of 33171-05-0

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Atomic zinc sites with hierarchical porous carbon for high-throughput chemical screening with high loading capacity and stability was written by Zhou, Mingyue;Wu, Xuan;Li, Yan;Zhang, Huixia;Liu, Qinghua;Song, Linlin;Wang, Caiyun;Law, Betty Yuen Kwan;Jiang, Zhihong;Zhang, Wei. And the article was included in Pharmacological Research in 2022.COA of Formula: C19H16O4 The following contents are mentioned in the article:

Alzheimer’s disease (AD) is a neurodegenerative disease associated with aging, and the number of people affected is rapidly increasing. Abnormally hyperphosphorylated tau filaments and extracellular deposits of amyloid β-peptides (Aβ) fibrils are two important pathol. hallmarks of AD. Currently, stopping the production of Aβ and blocking its aggregation is the main strategy for the treatment of AD. Turmeric is effective in treating neurodegenerative diseases, but there is no effective way to identify active compounds from their complicated chem. compositions Instead of using conventional extraction and separation methods with low efficiency and time-consuming, our group tried to use at. materials in high-throughput chem. screening due to their structural characteristics and the unique advantages of surface at. Herein, a novel at. zinc sites with hierarchical porous carbon (Zn-HPC) was synthesized to quickly screen potential inhibitors of Aβ aggregation in turmeric. As-combined Aβ@Zn-HPC demonstrates superior storage stability and high selectivity, outperforming the most reported supporters for ligand fishing. Five compounds with strong affinity on Aβ@Zn-HPC were selected by high-performance liquid chromatog.-hybrid linear ion trap/orbitrap mass spectrometer after incubation with turmeric extract Finally, it was shown that curcumin and bisdemethoxycurcumin can inhibit Aβ aggregation by using thioflavin-T fluorescence assay and biolayer interferometry. A new application for the accurate identification of Aβ aggregation inhibitors from turmeric were developed based on the active compounds possessing binding affinity to Aβ to inhibit its aggregation. The developed method could provide a promising tool for efficient drug discovery from natural product resources. This study involved multiple reactions and reactants, such as Bisdemethoxycurcumin (cas: 33171-05-0COA of Formula: C19H16O4).

Bisdemethoxycurcumin (cas: 33171-05-0) belongs to ethers. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. COA of Formula: C19H16O4

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Protective effects of Tiaoganquzhi decoction in treating inflammatory injury of nonalcoholic fatty liver disease by promoting CGI-58 and inhibiting expression of NLRP3 inflammasome was written by Zhang, Huicun;Gao, Xiang;Chen, Pengmin;Wang, Hongbing. And the article was included in Frontiers in Pharmacology in 2022.Related Products of 33171-05-0 The following contents are mentioned in the article:

Tiaoganquzhi Decoction (TGQZD) is a traditional Chinese herbal formulation demonstrated to be a clin. effective treatment for nonalcoholic fatty liver disease (NAFLD), although details concerning its clin. mechanism are poor. This study aimed to explore the mechanism of TGQZD on improvement of inflammatory damage and dyslipidemia caused by NAFLD through the CGI-58/ROS/NLRP3 inflammasome pathway. In our research, the in vivo protective effects of TGQZD on HFD-induced liver injury in rats and in vitro using lipopolysaccharide (LPS) + palmitate (PA)-stimulated HepG-2 cells model. Histol. changes were evaluated by hematoxylin-eosin and Oil Red O staining. Inflammatory cytokines and protein expression were analyzed by ELISA, Real time PCR and western blotting. Liver function, blood lipids, free fatty acids (FFA), and reactive oxygen species (ROS) were determined by biochem. detection. Our results indicated that TGQZD exhibited anti-inflammatory activity, reduced the severity of NAFLD and ameliorated the pathol. changes. Further, TGQZD improved liver function and lipid metabolism in NAFLD rats. TGQZD lowered serum aspartate aminotransferase, alanine aminotransferase, triglyceride, and total cholesterol levels. TGQZD suppressed the formulation of FFA and ROS. It also reduced the expression and release of the inflammatory cytokine interleukin-1β by promoting CGI-58 expression and inhibiting the expression of FFA, TNF-α, and the NLRP3 inflammasome induced by ROS. TGQZD exhibited anti-inflammatory effects via the CGI-58, ROS and NLRP3 inflammasome pathway in vivo and in vitro, resp. Our findings demonstrated that TGQZD is a useful and effective therapeutic agent for treating NAFLD via promotion of CGI-58 to inhibit the expression of ROS-induced NLRP3 inflammasome. This study involved multiple reactions and reactants, such as Bisdemethoxycurcumin (cas: 33171-05-0Related Products of 33171-05-0).

Bisdemethoxycurcumin (cas: 33171-05-0) belongs to ethers. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Related Products of 33171-05-0

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Influence of lipid matrix composition on biopharmaceutical properties of lipid nanoparticles was written by Keck, Cornelia M.;Specht, David;Bruessler, Jana. And the article was included in Journal of Controlled Release in 2021.HPLC of Formula: 33171-05-0 The following contents are mentioned in the article:

Lipid nanoparticles (LN) were invented in the early 1990ties and can be exploited for oral and topical drug delivery to increase the bioavailability of lipophilic active compounds The lipid matrix of the LN can be composed of solid lipids or of a mixture of liquid and solid lipids. The influence of the lipid matrix composition of LN on the dermal penetration efficacy is not known and was therefore investigated in this study. For this the whole spectrum of LN, that means NE (100% liquid lipid), SLN (100% solid lipid) and NLC that contained low, medium and high amounts of oil were produced and characterized in regard to size, zeta potential, crystallinity and in-vitro release. In addition, the dermal penetration efficacy was determined ex-vivo and the bio-phys. skin parameters, i.e., spreadability on skin, skin hydration, skin friction and transepidermal water loss were also assessed. Results demonstrate the tremendous influence of the lipid matrix composition on the biopharmaceutical properties of the LN but showed only minor differences in the physico-chem. properties of the particles. The physico-chem. properties of the LN and the in-vitro release data were not clearly linked to the dermal penetration efficacy, because also other parameters, e.g., skin hydration, spreadability of the formulation on skin and/or film formation of the LN on skin were found to be important parameters that influence the dermal penetration efficacy. Therefore, to allow for the development of effective LN formulations with tailor-made biopharmaceutical properties, not only the physico-chem. properties and in-vitro drug release profiles but also the most relevant biopharmaceutical properties of the LN should be assessed during the formulation development of LN. This study involved multiple reactions and reactants, such as Bisdemethoxycurcumin (cas: 33171-05-0HPLC of Formula: 33171-05-0).

Bisdemethoxycurcumin (cas: 33171-05-0) belongs to ethers. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.HPLC of Formula: 33171-05-0

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Bisdemethoxycurcumin alleviates vandetanib-induced cutaneous toxicity in vivo and in vitro through autophagy activation was written by Jin, Ying;Chen, Xueqin;Gao, Zizheng;Shen, Xiaofei;Fu, Huangxi;Pan, Zezheng;Yan, Hao;Yang, Bo;He, Qiaojun;Xu, Zhifei;Luo, Peihua. And the article was included in Biomedicine & Pharmacotherapy in 2021.Application of 33171-05-0 The following contents are mentioned in the article:

High incidence of cutaneous toxicity ranging from 29.2% to 71.2% has been reported during clin. use of vandetanib, which is a multi-target kinase inhibitor indicated for the treatment of unresectable medullary thyroid carcinoma. The cutaneous toxicity of vandetanib has limited its clin. benefits, but the underlying mechanisms and protective strategies are not well studied. Hence, we firstly established an in vivo model by continuously administrating vandetanib at 55 mg/kg/day to C57BL/6 for 21 days and verified that vandetanib could induce skin rash in vivo, which was consistent with the clin. study. We further cultured HaCaT and NHEK cells, the immortalized or primary human keratinocyte line, and investigated vandetanib (0-10μM, 0-24 h)-caused alteration in cellular survival and death processes. The western blot showed that the expression level of apoptotic-related protein, c-PARP, c-Caspase 3 and Bax were increased, while the anti-apoptotic protein Bcl2 and MCL1 level were decreased. Meanwhile, vandetanib downregulated mitochondrial membrane potential which in turn caused the release of Cytochrome C, excessive production of reactive oxygen species and DNA damage. Furthermore, we found that 5μM bisdemethoxycurcumin partially rescued vandetanib-induced mitochondria pathway-dependent keratinocyte apoptosis via activation of autophagy in vivo and in vitro, thereby ameliorated cutaneous toxicity. Conclusively, our study revealed the mechanisms of vandetanib-induced apoptosis in keratinocytes during the occurrence of cutaneous toxicity, and suggested bisdemethoxycurcumin as a potential protective drug. This work provided a potentially promising therapeutic strategy for the treatment of vandetanib-induced cutaneous toxicity. This study involved multiple reactions and reactants, such as Bisdemethoxycurcumin (cas: 33171-05-0Application of 33171-05-0).

Bisdemethoxycurcumin (cas: 33171-05-0) belongs to ethers. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Application of 33171-05-0

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Natural Antioxidant Extracted Waste Cooking Oil as Sustainable Biolubricant Formulation in Tribological and Rheological Applications was written by Singh, Nisha;Agarwal, Priyanka;Porwal, Suheel K.. And the article was included in Waste and Biomass Valorization in 2022.Recommanded Product: 33171-05-0 The following contents are mentioned in the article:

Developing eco-friendly formulations using waste cooking oil as renewable biomass is of great interest and com. importance in the fuels and lubricant industry. This manuscript reports novel study on preparing a biolubricant formulations as WCO-1, WCO-2 and WCO-3 by blending the curcumin extracted soybean waste cooking oil in three different compositions viz 10%, 20%, 30% volume/volume with the mineral base oil N-150. Curcumin was extracted as a natural antioxidant in 0.5 wt% waste cooking oil to inhibit thermal oxidation This study comprises a detailed anal. in terms of tribol., rheol. and thermophys. characteristics such as viscosity, viscosity index, pour point and flash point parameters of the biolubricant by standard ASTM methods. Further, tribol. and rheol. anal. was done by the four-ball wear tester and Anton Paar, MCR-72, resp. The thermophys. evaluation of WCO formulated biolubricant has shown excellent properties. The viscosity index of the formulated biolubricant increases with an increase in the concentration of waste cooking oil. In contrast, the pour point has also been depressing at lower temperature conditions. Thus, WCO based biolubricant was found to be more effective at extreme temperature conditions than the mineral base oil (N-150). Rheol. studies have indicated the non-Newtonian behavior of the biolubricant with an increase in shear rate. Whereas, tribol. anal. demonstrates that wear scar diameter has significantly reduced from 0.685 to 0.573 mm, and the coefficient of friction decreased from 0.117 to 0.080 with respect to the mineral base oil. Thus, a straightforward green approach has been discovered by directly utilizing waste cooking oil for biolubricant formulation. This study involved multiple reactions and reactants, such as Bisdemethoxycurcumin (cas: 33171-05-0Recommanded Product: 33171-05-0).

Bisdemethoxycurcumin (cas: 33171-05-0) belongs to ethers. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Recommanded Product: 33171-05-0

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem