Tag: 100-200

Ndima, Lubabalo; Hosten, Eric C.; Betz, Richard published an article in 2021. The article was titled 《Crystal structure of 2-hydroxy-4-methoxy benzaldehyde, C8H8O3》, and you may find the article in Zeitschrift fuer Kristallographie – New Crystal Structures.Recommanded Product: 673-22-3 The information in the text is summarized as follows:

C8H8O3, monoclinic, P21/c (number 14), a = 6.3037(3) Å, b = 33.102(2) Å, c = 7.0471(4) Å, β = 102.105(3)°, V = 1437.79(14) Å3, Z = 8, R gt(F) = 0.0433, wR ref(F 2) = 0.1087, T = 200 K. In the experiment, the researchers used many compounds, for example, 2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3Recommanded Product: 673-22-3)

2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3) is the main component of root bark essential oil of Periploca sepium Bunge. It is a potential tyrosinase inhibitor present in African medicinal plants. 2-Hydroxy-4-methoxybenzaldehyde was used in the synthesis of Schiff base ligand.Recommanded Product: 673-22-3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Abdollahi, Maryam F.; You, Jian; Wang, Tao; Zhao, Yuming published their research in Chemical Communications (Cambridge, United Kingdom) in 2021. The article was titled 《Molecular tuning of the crystallization-induced emission enhancement of diphenyl-dibenzofulvene luminogens》.HPLC of Formula: 10365-98-7 The article contains the following contents:

The absorption and emission properties of various diphenyl-dibenzofulvene (DP-DBF) derivatives were investigated, and their crystallization-induced emission enhancement (CIEE) performances were found to show a clear correlation with the twist angle around the C=C bond of the DP-DBF structure. The experimental process involved the reaction of 3-Methoxyphenylboronic acid(cas: 10365-98-7HPLC of Formula: 10365-98-7)

3-Methoxyphenylboronic acid(cas: 10365-98-7) belongs to boronic acids. Boronic acids are mild Lewis acids which are generally stable and easy to handle, making them important to organic synthesis.HPLC of Formula: 10365-98-7

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

SDS of cas: 33797-34-1On March 31, 2018, Manuri, Brahmayya; Dasi, Samsonu; Korla, Praveen Kumar published an article in Proceedings of the National Academy of Sciences, India, Section A: Physical Sciences. The article was 《Neat Synthesis of Substituted Benzoic Acids Employing TBHP/Oxone Catalyst and Study of Their Anti-oxidant Activity》. The article mentions the following:

In the present study, a variety of benzyl alcs. are synthesized from corresponding benzoic acids employing TBHP/oxone and FeCl3 as an effective and selective catalyst under solvent free conditions. The conversion rate and yields of the products are significant. The advantages of the selected catalyst are: cheaply available and more selectivity of the product formations rather than the formation of any undesired byproducts. The synthesized compounds were tested for anti-oxidant activities. In the experiment, the researchers used (3-Methoxy-2-methylphenyl)methanol(cas: 33797-34-1SDS of cas: 33797-34-1)

(3-Methoxy-2-methylphenyl)methanol(cas: 33797-34-1) belongs to ethers.SDS of cas: 33797-34-1Although ethers resist hydrolysis, they are cleaved by hydrobromic acid and hydroiodic acid. Hydrogen chloride cleaves ethers only slowly.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Recommanded Product: 1-Bromo-3-methoxybenzeneIn 2019 ,《Structure-based development of new RAS-effector inhibitors from a combination of active and inactive RAS-binding compounds》 appeared in Proceedings of the National Academy of Sciences of the United States of America. The author of the article were Cruz-Migoni, Abimael; Canning, Peter; Quevedo, Camilo E.; Bataille, Carole J. R.; Bery, Nicolas; Miller, Ami; Russell, Angela J.; Phillips, Simon E. V.; Carr, Stephen B.; Rabbitts, Terence H.. The article conveys some information:

The RAS gene family is frequently mutated in human cancers, and the quest for compounds that bind to mutant RAS remains a major goal, as it also does for inhibitors of protein-protein interactions. We have refined crystallization conditions for KRAS169Q61H-yielding crystals suitable for soaking with compounds and exploited this to assess new RAS-binding compounds selected by screening a protein-protein interaction-focused compound library using surface plasmon resonance. Two compounds, referred to as PPIN-1 and PPIN-2, with related structures from 30 initial RAS binders showed binding to a pocket where compounds had been previously developed, including RAS effector protein-protein interaction inhibitors selected using an intracellular antibody fragment (called Abd compounds). Unlike the Abd series of RAS binders, PPIN-1 and PPIN-2 compounds were not competed by the inhibitory anti-RAS intracellular antibody fragment and did not show any RAS-effector inhibition properties. By fusing the common, anchoring part from the two new compounds with the inhibitory substituents of the Abd series, we have created a set of compounds that inhibit RAS-effector interactions with increased potency. These fused compounds add to the growing catalog of RAS protein-protein inhibitors and show that building a chem. series by crossing over two chem. series is a strategy to create RAS-binding small mols. After reading the article, we found that the author used 1-Bromo-3-methoxybenzene(cas: 2398-37-0Recommanded Product: 1-Bromo-3-methoxybenzene)

1-Bromo-3-methoxybenzene(cas: 2398-37-0) can be used in chemical reaction as intermediates to obtain target materials such as dyes, pharmaceuticals, perfumes, photoinitiators and agrochemicals.Recommanded Product: 1-Bromo-3-methoxybenzene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《Palladium(II) complexes with thione and thioalkylated thiosemicarbazones: Electrochemical, antimicrobial and thermogravimetric investigations》 was written by Eglence-Bakir, Songul; Sahin, Musa; Salt, Betul Zehra; Tuzun, Elif; Kara, Emel Mataraci; Atun, Gulten; Cavus, Selva; Kizilcikli, Irfan. Electric Literature of C8H8O3 And the article was included in Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy in 2020. The article conveys some information:

Four methoxy substitute salicylidene thiosemicarbazones were synthesized. The reaction of both thione and thioalkylated thiosemicarbazones with PdCl2 in ethanol yields ONS-coordinated chelate complexes with general formula [Pd(L)Cl]. The structures of eight compounds were characterized by using anal. and spectroscopic methods. Electrochem. of the Pd(II) complexes was studied using cyclic voltammetric technique. The CVs of the complexes were quite complicate because of some oxidative responses of the ligands which proceed by forming conjugated -N:CH-, -HC:CH- and -N:CH-HC:CH- groups. Two cathodic responses attributed to one electron reduction of Pd(II)/(I) and Pd(I)/(0) were observed for the central ion coordinated with S atom of H3C-S- group whereas only one reduction peak appeared when the Pd(II) coordinated with S atom of >C:S group of thiosemicarbazone ligand. The latter also showed an addnl. anodic response assigned to Pd(II)/(III) oxidation Thermogravimetric anal. (TGA) technique was used to investigate and compare the thermal properties of the ligands and their metal complexes. In vitro antimicrobial activity of thiosemicarbazones and their complexes was evaluated against four Gram-neg. bacteria, three Gram-pos. bacteria, and antifungal activity against three fungi. After reading the article, we found that the author used 2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3Electric Literature of C8H8O3)

2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3) is the main component of root bark essential oil of Periploca sepium Bunge. It is a potential tyrosinase inhibitor present in African medicinal plants. 2-Hydroxy-4-methoxybenzaldehyde was used in the synthesis of Schiff base ligand.Electric Literature of C8H8O3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Bruce, Michael I.; Head, Nicholas J.; White, Allan H.; Skelton, Brian W. published an article on January 31 ,2004. The article was titled 《1,4-Diethynyl-2,5-dimethoxybenzene at ca 150 K》, and you may find the article in Acta Crystallographica, Section C: Crystal Structure Communications.Formula: C12H10O2 The information in the text is summarized as follows:

The principal determinants of packing in crystals of the title compound, C12H10O2, which has crystallog. imposed inversion symmetry, are interactions between the alkyne H atoms and the methoxy O atoms [H···O = 2.39(1) Å]. Crystallog. data are given. In the experiment, the researchers used many compounds, for example, 1,4-Diethynyl-2,5-dimethoxybenzene(cas: 74029-40-6Formula: C12H10O2)

1,4-Diethynyl-2,5-dimethoxybenzene(cas: 74029-40-6) belongs to ethers.Formula: C12H10O2Although ethers resist hydrolysis, they are cleaved by hydrobromic acid and hydroiodic acid. Hydrogen chloride cleaves ethers only slowly.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《Synthesis of 5-(aminomethylidene)imidazol-4-ones by using N,N-dialkylformamide acetals》 was published in Chemistry of Heterocyclic Compounds (New York, NY, United States) in 2020. These research results belong to Zaitseva, Elvira R.; Smirnov, Alexander Yu.; Ivanov, Igor A.; Mineev, Konstantin S.; Baranov, Mikhail S.. Category: ethers-buliding-blocks The article mentions the following:

A simple methodol. for the synthesis of various 5-(aminomethylidene)imidazol-4-ones I [R = NMe2, pyrrolidin-1-yl, piperidin-1-yl, 4-[ethoxy(oxo)methane]piperidin-1-yl, morpholin-4-yl; R1 = Me, Et] by condensation reactions of imidazol-4-one that was prepared in situ and acetals of N,N-dialkylformamides RCH(OR2)2 (R2 = Me, Et) has been described. In addition to this study using N,N-Dimethylformamide Dimethyl Acetal, there are many other studies that have used N,N-Dimethylformamide Dimethyl Acetal(cas: 4637-24-5Category: ethers-buliding-blocks) was used in this study.

N,N-Dimethylformamide Dimethyl Acetal(cas: 4637-24-5) belongs to anime. Reaction with nitrous acid (HNO2), which functions as an acylating agent that is a source of the nitrosyl group (―NO), converts aliphatic primary amines to nitrogen and mixtures of alkenes and alcohols corresponding to the alkyl group in a complex process. This reaction has been used for analytical determination of primary amino groups in a procedure known as the Van Slyke method.Category: ethers-buliding-blocks

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《Synthesis of the first dibenzo-4,12-dithio-8-azacrownophanes containing γ-arylpyridine subunit》 was published in Chemistry of Heterocyclic Compounds (New York, NY, United States) in 2020. These research results belong to Thi, Thanh Tam Pham; Do, Thao Thuyen; Nguyen, Tien Dat; Luu, Van Boi; Polyakova, Elena I.; Thi, Thanh Van Tran; Le, Tuan Anh. COA of Formula: C8H8O2 The article mentions the following:

Dibenzo-4,12-dithio-8-azacrownophanes containing γ-arylpyridine subunit and thiocrown fragment I (R = 2-OMe, 3-NO2) were synthesized in one step from 1,5-bis(2-acetylphenylsulfanyl)-3-oxapentane, aryl aldehydes RCHO, and ammonium acetate. After reading the article, we found that the author used 2-Methoxybenzaldehyde(cas: 135-02-4COA of Formula: C8H8O2)

2-Methoxybenzaldehyde(cas: 135-02-4) is used as a flavor agent in foods including nonalcoholic/alcoholic beverages, baked goods, chewing gum, confections, frozen dairy, fruit ices, hard/soft candy, instant coffee, tea, Jams, jellies, and milk products. It also has been used to obtain good enantioselectivities using Cu(OAc)(2)-bis(oxazolines) via hydrogen bonding in asymmetric Henry reaction.COA of Formula: C8H8O2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem