Tag: 100-200

《Stereoselective synthesis of trifluoromethyl-substituted 2H-furan-amines from enaminones》 was published in Chemical Communications (Cambridge, United Kingdom) in 2020. These research results belong to Liang, Xiaoyu; Guo, Pan; Yang, Wenjie; Li, Meng; Jiang, Chengzhou; Sun, Wangbin; Loh, Teck-Peng; Jiang, Yaojia. Recommanded Product: N,N-Dimethylformamide Dimethyl Acetal The article mentions the following:

A straightforward strategy for synthesis of highly functionalized trifluoromethyl 2H-furans was described. The copper catalyzed method relies on a cascade cyclic reaction between enaminones and N-tosylhydrazones. This method allowed the synthesis of 2-amino-3-trifluoromethyl-substituted 2H-furan derivatives carrying a quaternary stereogenic center as single diastereomers. The proposed reaction mechanism involved an amino-cyclopropane intermediate formed in the cyclopropanation of enaminones. The developed method tolerated a broad spectrum of functionalities and the obtained 2H-furan derivatives were useful synthetic intermediates for preparing other trifluoromethyl-substituted compounds The experimental process involved the reaction of N,N-Dimethylformamide Dimethyl Acetal(cas: 4637-24-5Recommanded Product: N,N-Dimethylformamide Dimethyl Acetal)

N,N-Dimethylformamide Dimethyl Acetal(cas: 4637-24-5) belongs to anime.Typically the presence of an amine functional group is deduced by a combination of techniques, including mass spectrometry as well as NMR and IR spectroscopies. 1H NMR signals for amines disappear upon treatment of the sample with D2O. In their infrared spectrum primary amines exhibit two N-H bands, whereas secondary amines exhibit only one.Recommanded Product: N,N-Dimethylformamide Dimethyl Acetal

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Computed Properties of C7H7BrOIn 2022 ,《Metal-organic framework grown in situ on chitosan microspheres as robust host of palladium for heterogeneous catalysis: Suzuki reaction and the p-nitrophenol reduction》 was published in International Journal of Biological Macromolecules. The article was written by Wang, Gongshu; Wang, Jiwei; Chen, Zhangpei; Hu, Jianshe. The article contains the following contents:

In this study, the metal-organic framework ZIF-8 has been successfully planted on the surface of chitosan microspheres (CS/PDA@ZIF-8) using polydopamine as connecting material for the first time, which avoids the use of expensive, non-renewable, and non-biodegradable polystyrene microspheres commonly used as templates to prepare core-shell structures. Moreover, the metal-organic framework ZIF-8 was prepared specially by three different methods and all characterized by SEM, TEM, and BET, and the ZIF-8 shell prepared at room temperature presents a regular morphol., uniform size, large sp. surface area (353.1 m2/g) than the shells prepared by the other methods including. The CS/PDA@ZIF-825@Pd with high catalytic activity and high stability was especially prepared by encapsulating Pd nanoparticles into the pores of CS/PDA@ZIF-825. Notably, the fabricated catalyst performed well in an array of reactions, for example the Kapp value of the p-nitrophenol reduction reaction reached 0.0426 s-1, and the TOF of the Suzuki coupling reaction reached 128 h-1. In addition, the ZIF-67, UiO-66, UiO-66-NH2, HKUST-1, and NH2-MIL-53(Al) were also grown on chitosan microcapsules successively to prepare the core-shell microspheres, which prove the universal applicability of this strategy. And beyond that, the introduction of chitosan microspheres endows the material with biodegradable properties and excellent recycling properties. The experimental part of the paper was very detailed, including the reaction process of 1-Bromo-3-methoxybenzene(cas: 2398-37-0Computed Properties of C7H7BrO)

1-Bromo-3-methoxybenzene(cas: 2398-37-0) can be used in chemical reaction as intermediates to obtain target materials such as dyes, pharmaceuticals, perfumes, photoinitiators and agrochemicals.Computed Properties of C7H7BrO

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Ether – Wikipedia,
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Recommanded Product: 2-(Benzyloxy)acetaldehydeIn 2022 ,《Cp*Rh(III)/boron hybrid catalysis for directed C-H addition to β-substituted α,β-unsaturated carboxylic acids》 appeared in Chemical Communications (Cambridge, United Kingdom). The author of the article were Tanaka, Ryo; Hirata, Yuki; Kojima, Masahiro; Yoshino, Tatsuhiko; Matsunaga, Shigeki. The article conveys some information:

The C-H bond addition reaction of 2-phenylpyridine derivatives with α,β-unsaturated carboxylic acids catalyzed by Cp*Rh(III)/BH3·SMe2 is reported. Activation of C-H bonds with the rhodium catalyst and activation of α,β-unsaturated carboxylic acids with the boron catalyst cooperatively work, and a BINOL-urea hybrid ligand significantly improved the reactivity. With the optimized hybrid catalytic system, various β-disubstituted carboxylic acids were obtained under mild reaction conditions. In addition to this study using 2-(Benzyloxy)acetaldehyde, there are many other studies that have used 2-(Benzyloxy)acetaldehyde(cas: 60656-87-3Recommanded Product: 2-(Benzyloxy)acetaldehyde) was used in this study.

2-(Benzyloxy)acetaldehyde(cas: 60656-87-3) is a non-natural aldehyde. It undergoes enantioselective Mukaiyama aldol reaction with silylketene acetal nucleophiles in the presence of C2-symmetric bis(oxazolinyl)pyridine Cu(II) complex (catalyst).Recommanded Product: 2-(Benzyloxy)acetaldehyde

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COA of Formula: C8H8O2In 2020 ,《Nanostructural Cu-Doped ZnO Hollow Spheres as an Economical and Recyclable Catalyst in the Synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-diones and Pyrazolo[1,2-a][1,2,4]triazole-1,3-diones》 appeared in Organic Preparations and Procedures International. The author of the article were Maleki, Behrooz; Nejat, Razieh; Alinezhad, Heshmatollah; Mousavi, Seyed Mohsen; Mahdavi, Behnam; Delavari, Maryam. The article conveys some information:

A convenient one-pot three component cyclocondensation reaction for the preparation of 1H-pyrazolo[1,2-b]phthalazine-5,10-diones and pyrazolo[1,2-a][1,2,4]triazole-1,3-dione derivatives, using nano hollow sphere Cu-ZnO as an economical catalyst under solvent-free conditions has been developed. This method has advantages such as high yields, short reaction times, easy work-up, ease of separation and reusability of the catalyst. This work will stimulate further research on this useful catalyst for the preparation of heterocyclic systems. In the experimental materials used by the author, we found 2-Methoxybenzaldehyde(cas: 135-02-4COA of Formula: C8H8O2)

2-Methoxybenzaldehyde(cas: 135-02-4) is found in cassia oil, cinnamon bark, and cinnamon bark oil. It is a clear colorless liquid with a strong aroma. It has been used to examine the acaricidal activity of Periploca sepium oil and its active component against Tyrophagus putrescentiae.COA of Formula: C8H8O2

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HPLC of Formula: 135-02-4In 2019 ,《One-Pot Synthesis of Polyhydroquinolines Catalyzed by ZnCl2 Supported on Nano Fe3O4@SiO2》 appeared in Organic Preparations and Procedures International. The author of the article were Maleki, Behrooz; Alinezhad, Heshmatollah; Atharifar, Hengameh; Tayebee, Reza; Mofrad, Akram Vedad. The article conveys some information:

The one-pot synthesis of polyhydroquinolines using Fe3O4@SiO2/ZnCl2 as a nanocatalyst. This catalyst is excellent for this synthesis, giving pure products in high yields and short reaction times. An important aspect is the recyclability of this nanocatalyst, showing its economical and green qualities. The results came from multiple reactions, including the reaction of 2-Methoxybenzaldehyde(cas: 135-02-4HPLC of Formula: 135-02-4)

2-Methoxybenzaldehyde(cas: 135-02-4) is found in cassia oil, cinnamon bark, and cinnamon bark oil. It is a clear colorless liquid with a strong aroma. It has been used to examine the acaricidal activity of Periploca sepium oil and its active component against Tyrophagus putrescentiae.HPLC of Formula: 135-02-4

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2022,Hanumanagouda, H.; Mathada, Manjunatha Harihara; Basavaraja, K. M. published an article in Journal of Applicable Chemistry (Lumami, India). The title of the article was 《Curtius rearrangement reactions using 7-methoxybenzofuran-2-carbonylazide》.Related Products of 150-19-6 The author mentioned the following in the article:

The synthetic investigation of 7-methoxybenzofuranyl-carbamates (7-Methoxy-benzofuran-2-yl)-carbamic acid Et ester and I (R1 = C6H5, 4-ClC6H4, 2-ClC6H4, etc.) and carbamides II (R2 = C6H5, 4-ClC6H4, cyclohexyl, etc.) via the Curtius rearrangement of 7-methoxybenzofuran-2-carbonylazide has been reported. The required intermediate carbonyl azide was synthesized from ethyl-7-methoxybenzofuran-2-carboxylate by two established synthetic routes: (1) 7-methoxy-benzofuran-2-carboxylic acid and 7-methoxy-benzofuran-2-carbonyl chloride and (2) 7-methoxy-benzofuran-2-carboxylic acid hydrazide. The carbonyl azide was subjected to Curtius rearrangement in anhydrous medium with ethanol and various aromatic phenols to obtain carbamates (7-methoxy-benzofuran-2-yl)-carbamic acid Et ester and I while with primary amines and cyclohexylamine to obtain carbamides II. The structures of all the synthesized compounds I and II were confirmed by their IR, 1HNMR and mass spectral data. All the newly synthesized compounds I and II were screened for anti bacterial activity and antifungal activity. Few selected compounds were screened for their anti oxidant properties and DNA cleavage studies. Few compounds exhibited appreciable activity. After reading the article, we found that the author used m-Methoxyphenol(cas: 150-19-6Related Products of 150-19-6)

m-Methoxyphenol(cas: 150-19-6) may be used in synthesis of:C(4) symmetric calix[4]resorcinarene, 2-nitroso-5-methoxyphenol, 6-methoxy-2(3H)-benzoxazoloneRelated Products of 150-19-6

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Cao, Haijie; Wang, Kuikui; Yang, Zhengqiang; Wu, Shijie; Han, Dandan published an article in 2021. The article was titled 《Quantum chemical study on the ozonolysis mechanism of guaiacol and the structure-reactivity relationship of phenols with hydroxyl, methoxy, and methyl substituents》, and you may find the article in Chemical Engineering Journal (Amsterdam, Netherlands).Related Products of 150-19-6 The information in the text is summarized as follows:

Quantum chem. calculations with the M06-2X method were performed to uncover the ozonolysis mechanism of guaiacol and several hydroxylated, methoxylated, and methylated phenols to improve the understanding of the ozone-induced attenuation of phenolic compounds The detailed kinetic properties were obtained by the transition state theory (TST) and the Rice – Ramsperger – Kassel – Marcus (RRKM) theory. Results confirm that the primary ozonides originated from guaiacol occupy considerably long retention time than the short-lived primary ozonides formed from vinyl-type compounds in the air. The TST rate constant of guaiacol ozonolysis is calculated with a value of 8.81 x 10-20 cm3 mol.-1 s-1 at room temperature The RRKM results prove that the rate constant is pos. dependent on temperature but shows no relation with pressure. The reactivity of substituted phenols exhibits a strong correlation with the ozone affinity of carbon atoms and the orbital energy difference (ELo-Hac) between the LUMO of O3 and the HOMO of phenols. The substituents can reduce the value of ELo-Hac and improve the phenols’ reactivity, especially when they locate at the ortho- and para-position. The substituents also improve the ozone affinity of carbon atoms due to the electron-withdrawing effect. The Me group delivers a moderate impact on the reactivity compared to hydroxyl and methoxy groups. The results came from multiple reactions, including the reaction of m-Methoxyphenol(cas: 150-19-6Related Products of 150-19-6)

m-Methoxyphenol(cas: 150-19-6) may be used in synthesis of:C(4) symmetric calix[4]resorcinarene, 2-nitroso-5-methoxyphenol, 6-methoxy-2(3H)-benzoxazoloneRelated Products of 150-19-6

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《Double connector to TiO2 surface in small molecule triphenyl amine dyes for DSSC applications》 was written by Ozkan, Eren; Mutlu, Adem; Zafer, Ceylan; Dincalp, Haluk. Recommanded Product: 10365-98-7This research focused ontitanium oxide triphenyl amine dye sensitized solar cell. The article conveys some information:

Two novel dyes 3a and 3b named triphenylamine groups containing donor-acceptor structural units have been explored to be used in dye sensitized solar cells as organic sensitizers. The absorption bands of the dyes were extended up to ∼ 550 nm with visible absorption maxima at 408-430 nm and optical band gaps of 2.44-2.47 eV. Compared to the methoxyphenyl-substituted dye, the introduction of triisopropylphenyl group instead of that increased fluorescence quantum yields and exhibited red-shift emission in chloroform. We have investigated the photovoltaic properties of DSSCs based on these metal free organic dyes. It has been found that the power conversion efficiency of DSSCs sensitized with methoxyphenyl based triphenylamine dye is higher than that for sensitized with triisopropylphenyl derivative In the experimental materials used by the author, we found 3-Methoxyphenylboronic acid(cas: 10365-98-7Recommanded Product: 10365-98-7)

3-Methoxyphenylboronic acid(cas: 10365-98-7) belongs to boronic acids. Boronic acids are mild Lewis acids which are generally stable and easy to handle, making them important to organic synthesis.Recommanded Product: 10365-98-7

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Ether – Wikipedia,
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Application In Synthesis of 3-Methoxyphenylboronic acidIn 2020 ,《Nickel-catalyzed regio- and diastereoselective hydroarylative and hydroalkenylative cyclization of 1,6-dienes》 was published in Chemical Communications (Cambridge, United Kingdom). The article was written by Xu, Zhengshuai; Tang, Yitian; Shen, Chaoren; Zhang, Hongru; Gan, Yuxin; Ji, Xiaolei; Tian, Xinxin; Dong, Kaiwu. The article contains the following contents:

An unprecedented nickel-catalyzed hydroarylative and hydroalkenylative cyclization of unsym. substituted 1,6-dienes with organoboronic acid was developed by using MeOH as the hydrogen source and employing com. available Ni(η2-1,5-cyclooctadiene)2 as the catalyst. A series of biol. interesting cyclic products I [X = O, NTs, C(CO2Et)2; R1 = H, Ph, 1-naphthyl, etc.; R2 = CH:CHCH2CH2CH3, Ph, 4-FC6H4, etc.] were afforded in moderate to excellent yields with high regio- and diastereoselectivities. In the experiment, the researchers used 3-Methoxyphenylboronic acid(cas: 10365-98-7Application In Synthesis of 3-Methoxyphenylboronic acid)

3-Methoxyphenylboronic acid(cas: 10365-98-7) belongs to boronic acids. Boronic acids are mild Lewis acids which are generally stable and easy to handle, making them important to organic synthesis.Application In Synthesis of 3-Methoxyphenylboronic acid

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Caliskan, Melike; Baran, Talat published their research in International Journal of Biological Macromolecules in 2021. The article was titled 《Decorated palladium nanoparticles on chitosan/δ-FeOOH microspheres: A highly active and recyclable catalyst for Suzuki coupling reaction and cyanation of aryl halides》.Name: 1-Bromo-3-methoxybenzene The article contains the following contents:

In this study, an eco-friendly and low cost magnetic nanocomposite consisting of chitosan/δ-FeOOH microspheres (CS/δ-FeOOH) was fabricated as a stabilizer by using a simple method. Pd Nanoparticles (Pd NPs) were decorated on designed CS/δ-FeOOH, and resulting Pd NPs@CS/δ-FeOOH microspheres were employed as a heterogeneous catalyst in construction of biaryls Ph-Ar [Ar = 4-MeC6H4, 4-NCC6H4, 3-O2N6H4, etc.] and benzonitriles ArCN [Ar = 3-Me6H4]. Pd NPs@CS/δ-FeOOH Microspheres efficiently catalyzed conversion of aryl iodides and bromides to desired biaryls within 3 h. Moreover, Pd NPs@CS/δ-FeOOH microspheres showed high catalytic potential against synthesis of benzonitriles by providing yields up to of 99% within 4 h. More importantly, it was proved that Pd NPs@CS/δ-FeOOH microspheres were able to be easily recycled and reused up to eight runs for both reactions. This study revealed that Pd NPs@CS/δ-FeOOH microspheres are useful and recyclable nanocatalysts, which catalyze synthesis of biaryl and benzonitriles with good reaction yields. The experimental process involved the reaction of 1-Bromo-3-methoxybenzene(cas: 2398-37-0Name: 1-Bromo-3-methoxybenzene)

1-Bromo-3-methoxybenzene(cas: 2398-37-0) is a compound useful in organic synthesis and other chemical processes. It is an intermediate used for pharmaceuticals, perfumes and agrochemicals.Name: 1-Bromo-3-methoxybenzene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem