Tag: 100-200

In 2019,Chinese Journal of Chemical Engineering included an article by Han, Hongjing; Li, Jinxin; Wang, Haiying; Xue, Feng; Chen, Yanguang; Zhang, Yanan; Wang, Yizhen; Zhang, Mei. Recommanded Product: m-Methoxyphenol. The article was titled 《Catalytic depolymerization of calcium lignosulfonate by NiMgFeOx derived from sub-micron sized NiMgFe hydrotalcite prepared by introducing hydroxyl compounds》. The information in the text is summarized as follows:

A new method for regulating the synthesis of NiMgFe hydrotalcites (NMF LDHs) with the addition of hydroxyl compounds was proposed. A series of NMF LDHs were prepared by the above method, and then were calcined to obtain the NiMgFeOx(NMFOx) samples. The NMFOxsamples were characterized by XRD, SEM, TG-DTG, XPS and CO2-TPD, resp. The catalytic performance of NMFOx for depolymerizing calcium lignosulfonate (CLS) was evaluated by hydrothermal reaction. The results showed that the addition of hydroxyl compounds favored reducing the particle sizes of NMF LDHs. For the depolymerization of CSL, the yield of liquid product increased from 45% to 75.8% with the addition of NMFOx-ethanol (NMFOxET). The liquid products were mainly phenolics, aromatics, ketones and esters. The total selectivity of oxy-containing compounds was over 90.6%, among them, the phenolics were approx. 35.2%. The valence of Ni and Fe, crystalline phase and basicity almost remained unchanged. The NMFOx-ET samples were recycled for the depolymerization of CLS, moreover, the NMFOx-ET samples had high activity and stability after 4 cycles. The results came from multiple reactions, including the reaction of m-Methoxyphenol(cas: 150-19-6Recommanded Product: m-Methoxyphenol)

m-Methoxyphenol(cas: 150-19-6) may be used in synthesis of:C(4) symmetric calix[4]resorcinarene, 2-nitroso-5-methoxyphenol, 6-methoxy-2(3H)-benzoxazoloneRecommanded Product: m-Methoxyphenol

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,Journal of the American Chemical Society included an article by Xu, Jiancong; Chen, Jingjing; Gao, Feng; Xie, Shuguang; Xu, Xiaohua; Jin, Zhong; Yu, Jin-Quan. Related Products of 150-19-6. The article was titled 《Sequential Functionalization of meta-C-H and ipso-C-O Bonds of Phenols》. The information in the text is summarized as follows:

The use of a template as a linchpin motif in directed remote C-H functionalization is a versatile yet relatively underexplored strategy. We have developed a template-directed approach to realizing one-pot sequential palladium-catalyzed meta-selective C-H olefination of phenols, and nickel-catalyzed ipso-C-O activation and arylation. Thus, this bifunctional template converts phenols to synthetically useful 1,3-disubstituted arenes. In the experiment, the researchers used m-Methoxyphenol(cas: 150-19-6Related Products of 150-19-6)

m-Methoxyphenol(cas: 150-19-6) may be used in synthesis of:C(4) symmetric calix[4]resorcinarene, 2-nitroso-5-methoxyphenol, 6-methoxy-2(3H)-benzoxazoloneRelated Products of 150-19-6

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,Russian Journal of Organic Chemistry included an article by Hakobyan, R. M.. HPLC of Formula: 4637-24-5. The article was titled 《Synthesis of Symmetrical Bisisoquinolinediones》. The information in the text is summarized as follows:

A method of synthesis of 1,1′-(alkanediyl)bis{3-cyano-4-[4,5,5-trimethyl-2-oxo-5H-furan-3-yl]-pyridin-2(1H)-ones} from the corresponding lactones is developed. The synthesized compounds underwent intramol. cyclization to form sym. 7,7′-(alkanediyl)bis{5-amino-3,3-dimethylfuro[3,4-f]isoquinoline-1,6(3H,7H)-diones}. The experimental part of the paper was very detailed, including the reaction process of N,N-Dimethylformamide Dimethyl Acetal(cas: 4637-24-5HPLC of Formula: 4637-24-5)

N,N-Dimethylformamide Dimethyl Acetal(cas: 4637-24-5) belongs to anime. Aniline, ethanolamines, and several other amines are major industrial commodities used in making rubber, dyes, pharmaceuticals, and synthetic resins and fibres and for a host of other applications. Most of the numerous methods for the preparation of amines may be broadly divided into two groups: (1) chemical reduction (replacement of oxygen with hydrogen atoms in the molecule) of members of several other classes of organic nitrogen compounds and (2) reactions of ammonia or amines with organic compounds.HPLC of Formula: 4637-24-5

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Related Products of 74029-40-6On May 15, 2009 ,《p-Diethynylbenzene-based molecular wires, Fe-CC-p-C6H2X2-CC-Fe [Fe = Fe(η5-C5Me5)(dppe)]: Synthesis, substituent effects and unexpected formation of benzodifuran complex》 appeared in Journal of Organometallic Chemistry. The author of the article were Matsuura, Yumi; Tanaka, Yuya; Akita, Munetaka. The article conveys some information:

P-diethynylbenzene-based mol. wires, [Fe]-CC-p-C6H2X2-CC-[Fe] (3; [Fe] = FeCp*(dppe)), were prepared from reactions of cyclopentadienyliron chloride with diethynylbenzenes and their wire-like performance is estimated from the KC and Vab values. Electron-donating substituents (X) improve the performance. The dinuclear benzodifuran complex 4 unexpectedly formed from the derivative with X = OH shows the performance comparable to 3. In the experimental materials used by the author, we found 1,4-Diethynyl-2,5-dimethoxybenzene(cas: 74029-40-6Related Products of 74029-40-6)

1,4-Diethynyl-2,5-dimethoxybenzene(cas: 74029-40-6) belongs to ethers.Oxygen is more electronegative than carbon, thus the alpha hydrogens of ethers are more acidic than those of simple hydrocarbons. Related Products of 74029-40-6 They are far less acidic than alpha hydrogens of carbonyl groups (such as in ketones or aldehydes), however.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《Benzaldehyde and derivatives N(4)-phenyl-3-thiosemicarbazones: synthesis, characterization and biological activity》 was written by Glinma, Bienvenu; Medegan, Sedami; Yayi, Eleonore; Kpoviessi, Salome; Bero, Joanne; Quetin-Leclercq, Joelle; Poupaert, Jacques; Accrombessi, Georges; Gbaguidi, Fernand. SDS of cas: 135-02-4This research focused onthiosemicarbazone preparation antiparasitic activity. The article conveys some information:

A class of small mols., thiosemicarbazones and derivatives have been studied over the last few years due to their wide pharmacol. versatility. Due to having this wide-spectrum biol. activity, interest on these compounds has been considerably increased in the pharmaceutical sector at the present time. Here, benzaldehyde and derivatives were used on N(4)-phenyl-3-thiosemicarbazide with glacial acetic acid to synthesize four thiosemicarbazones corresponding (1-4) in good yields (64-85%). Structures of compounds were characterized by spectrometric alanal.: FT-IR, NMR 1H & 13C and MS spectra. A theor. study based on their chem. structure has been made. In vitro antiparasitic activity of products has been evaluated on the on the bloodstream form of the strain 427 of Trypanosoma bruceibrucei. All compounds presented phys. properties compatible with reasonable pharmacokinetics and drug availability, but they showed a low half inhibitory concentration (IC50> 100 μM) and then were not actives on the trypanosomes tested. Other biol. activity would be explored on other pathogens. The experimental part of the paper was very detailed, including the reaction process of 2-Methoxybenzaldehyde(cas: 135-02-4SDS of cas: 135-02-4)

2-Methoxybenzaldehyde(cas: 135-02-4) is found in cassia oil, cinnamon bark, and cinnamon bark oil. It is a clear colorless liquid with a strong aroma. It has been used to examine the acaricidal activity of Periploca sepium oil and its active component against Tyrophagus putrescentiae.SDS of cas: 135-02-4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

HPLC of Formula: 4637-24-5In 2019 ,《Synthesis and Antibacterial Evaluation of Some New Thiazole-Based Polyheterocyclic Ring Systems》 was published in Journal of Heterocyclic Chemistry. The article was written by Abdel-Latif, Ehab; Almatari, Altaf S.; Abd-ElGhani, Ghada E.. The article contains the following contents:

2-Cyanoacetamido-thiazole (I) was employed as a key for the construction of 6-cyano-7-oxo-7H-thiazolo[3,2-a]pyrimidine which underwent reaction with hydrazine, malononitrile, Et cyanoacetate, and/or various 1,3-bi-nucleophilic reagents furnished the corresponding tri-heterocyclic and tetra-heterocyclic ring systems. In addition, the reactions of I with various types of arylidene-malononitriles and/or Et 3-aryl-2-cyanoacrylates yielded the corresponding 1-thiazolyl-pyridine derivatives Furthermore, treatment of the precursor I with carbon disulfide and Me iodide afforded the ketene dithioacetal derivative which cyclized upon heating with hydrazine and/or 2-aminobenzimidazole into the corresponding derivatives of N-(thiazol-2-yl)-1H-pyrazole-4-carboxamide and N-(thiazol-2-yl)benzimidazo[1,2-a]-pyrimidine-3-carboxamide. The antibacterial properties of these thiazole-based heterocycles were examined against panel of two bacterial strains. In the experimental materials used by the author, we found N,N-Dimethylformamide Dimethyl Acetal(cas: 4637-24-5HPLC of Formula: 4637-24-5)

N,N-Dimethylformamide Dimethyl Acetal(cas: 4637-24-5) belongs to anime. Amines have a free lone pair with which they can coordinate to metal centers. Amine–metal bonds are weaker because amines are incapable of backbonding, but they are still important for sensing applications.While stronger than hydrogen bonds, amine–metal bonds are still weaker than both covalent and ionic bonds.HPLC of Formula: 4637-24-5

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Name: 2-Hydroxy-4-methoxybenzaldehydeIn 2020 ,《Enantioselective Construction of Spirooxindole-Fused Cyclopenta[c]chromen-4-ones Bearing Five Contiguous Stereocenters via a Stepwise (3+2) Cycloaddition》 was published in Advanced Synthesis & Catalysis. The article was written by Vagh, Sandip Sambhaji; Karanam, Praneeth; Liao, Cheng-Chieh; Lin, Ting-Han; Liou, Yan-Cheng; Edukondalu, Athukuri; Chen, Yi-Ru; Lin, Wenwei. The article contains the following contents:

The bifunctional quinine-catalyzed stepwise (3+2) cycloaddition for the enantioselective construction of spirooxindole-fused cyclopenta[c]chromen-4-ones, e.g., I was developed. The reactions of 3-homoacylcoumarins and alkylidene oxindole electrophiles generate aforementioned spirooxindole-chromenone adducts bearing five contiguous stereocenters, of which one was the spiro all-carbon quaternary stereocenter in high yields (up to 99%) with excellent stereoselectivities (up to >20:1 dr and 99% ee). This methodol. was investigated for three different alkylidene oxindole electrophiles and could also be practically demonstrated on a gram scale. Mechanistic investigations revealed that the (3+2) cycloaddition for the enantioselective synthesis of spirooxindole-fused cyclopenta[c]chromen-4-ones was proceeding via a stepwise reaction pathway. In the experiment, the researchers used many compounds, for example, 2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3Name: 2-Hydroxy-4-methoxybenzaldehyde)

2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3) is the main component of root bark essential oil of Periploca sepium Bunge. It is a potential tyrosinase inhibitor present in African medicinal plants. 2-Hydroxy-4-methoxybenzaldehyde was used in the synthesis of Schiff base ligand.Name: 2-Hydroxy-4-methoxybenzaldehyde

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

SDS of cas: 135-02-4In 2020 ,《Experimental and DFT mechanistic insights into one-pot synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-diones under catalysis of DBU-based ionic liquids》 appeared in New Journal of Chemistry. The author of the article were Fallah-Ghasemi Gildeh, Sara; Mehrdad, Morteza; Roohi, Hossein; Ghauri, Khatereh; Fallah-Ghasemi Gildeh, Sahar; Rad-Moghadam, Kurosh. The article conveys some information:

Benzylation of DBU followed by anion exchange of the resulting salt with trifluoroacetate gave nearly quant. ionic liq [Bn-DBU][TFA]. It is shown here to be an efficient catalyst for the synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-diones I (Ar = 4-nitrophenyl, 3-chlorophenyl, 2-methylphenyl, etc.; X = CN, COOEt) via the three-component reaction of phthalhydrazide, aromatic aldehydes ArCHO, and active α-methylene nitriles XCH2CN. DFT calculations at the B3LYP/SVP level and the exptl. results are in agreement with a three-step mechanism for this reaction. Based on the DFT calculations, the catalytic effect largely arises from the intrinsic ionic properties of the ionic liquid rather than its action as a simple base. These calculations also predict the existence of two close-in-energy activated complexes whose rate determining roles and energies depend on their interaction with the anionic component of the ionic liquid, as [Bn-DBU][TFA] has shown a higher catalytic activity than [Bn-DBU][OAc]. This mechanistic approach opens up new and promising insights into the rational design of ionic liquid catalysts for the synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-diones I. The synthetic method presented here has several prominent advantages. The experimental part of the paper was very detailed, including the reaction process of 2-Methoxybenzaldehyde(cas: 135-02-4SDS of cas: 135-02-4)

2-Methoxybenzaldehyde(cas: 135-02-4) is found in cassia oil, cinnamon bark, and cinnamon bark oil. It is a clear colorless liquid with a strong aroma. It has been used to examine the acaricidal activity of Periploca sepium oil and its active component against Tyrophagus putrescentiae.SDS of cas: 135-02-4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,Russian Journal of General Chemistry included an article by Dyachenko, I. V.. Synthetic Route of C5H13NO2. The article was titled 《2-Cyano-3-(dimethylamino)prop-2-ene Thioamide: A New Reagent for Synthesis of Functionalized 4-Unsubstituted Ethyl Nicotinates and Nicotinonitriles》. The information in the text is summarized as follows:

Condensation of cyclopent(hex)ylidenecyanothioacetamide with N, N-dimethylformamide di-Me acetal led to the formation of a new reagent for organic synthesis: 2-cyano-3-(dimethylamino)prop-2-ene thioamide. On its basis a series of Et nicotinates and nicotinonitriles were synthesized by a vinyl substitution reaction. In the experiment, the researchers used many compounds, for example, N,N-Dimethylformamide Dimethyl Acetal(cas: 4637-24-5Synthetic Route of C5H13NO2)

N,N-Dimethylformamide Dimethyl Acetal(cas: 4637-24-5) belongs to anime. Examples of direct uses of amines and their salts are as corrosion inhibitors in boilers and in lubricating oils (morpholine), as antioxidants for rubber and roofing asphalt (diarylamines), as stabilizers for cellulose nitrate explosives (diphenylamine), as protectants against damage from gamma radiation (diarylamines), as developers in photography (aromatic diamines), as flotation agents in mining, as anticling and waterproofing agents for textiles, as fabric softeners, in paper coating, and for solubilizing herbicides.Synthetic Route of C5H13NO2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,Journal of Molecular Structure included an article by Maddila, Surya Narayana; Maddila, Suresh; Khumalo, Mandlenkosi; Bhaskaruni, Sandeep V. H. S.; Jonnalagadda, Sreekantha B.. Reference of 2-Methoxybenzaldehyde. The article was titled 《An eco-friendly approach for synthesis of novel substituted 4H-chromenes in aqueous ethanol under ultra-sonication with 94% atom economy》. The information in the text is summarized as follows:

An operational approach for synthesis of eleven substituted 4H-chromene derivatives I (R = 2-CH3OC6H4, 4-CF3C6H4, pyridin-3-yl, etc.; R1 = Me, Et) by one-pot, three-component reaction of aromatic aldehydes RCHO, Me/Et cyanoacetate and 5,5 di-Me 1,3-cyclohexadione through ultrasound irradiation, in the presence of aqueous ethanol under catalyst-free condition is reported. Different spectral methods, including 1H, 13C and 15N NMR and HRMS were utilized to characterize the new mols. Benefits of the eco-friendly method are fast reaction (10 min), excellent yields (92-98%), no column chromatog. and no byproducts. Reaction offers 94% atom economy and 100% carbon capture. In the part of experimental materials, we found many familiar compounds, such as 2-Methoxybenzaldehyde(cas: 135-02-4Reference of 2-Methoxybenzaldehyde)

2-Methoxybenzaldehyde(cas: 135-02-4) is used as a flavor agent in foods including nonalcoholic/alcoholic beverages, baked goods, chewing gum, confections, frozen dairy, fruit ices, hard/soft candy, instant coffee, tea, Jams, jellies, and milk products. It also has been used to obtain good enantioselectivities using Cu(OAc)(2)-bis(oxazolines) via hydrogen bonding in asymmetric Henry reaction.Reference of 2-Methoxybenzaldehyde

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem