Category: 99438-28-5

Frein, Jeffrey D. published the artcileNew Sources of Chemical Diversity Inspired by Biosynthesis: Rational Design of a Potent Epothilone Analog, Safety of (+)-B-Methoxydiisopinocampheylborane, the publication is Organic Letters (2009), 11(15), 3186-3189, database is CAplus and MEDLINE.

A concise total synthesis of (14S)-14-methoxyepothilone D (I) was accomplished. (14S)-14-Methoxyepothilone D represents a conceptually novel example of polyketide analog design based on an alternative biogenetic pattern of extender units. The significant biol. activity observed for this compound provides a foundation to support studies designed to prepare derivatives of this type through fermentation of genetically engineered organisms expressing the epothilone PKS gene cluster.

Organic Letters published new progress about 99438-28-5. 99438-28-5 belongs to ethers-buliding-blocks, auxiliary class Chiral,Aliphatic cyclic hydrocarbon, name is (+)-B-Methoxydiisopinocampheylborane, and the molecular formula is C21H37BO, Safety of (+)-B-Methoxydiisopinocampheylborane.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Meissner, Andreas published the artcileStereocontrolled synthesis of the macrolactone core of neopeltolide, Category: ethers-buliding-blocks, the publication is Tetrahedron Letters (2019), 60(5), 432-434, database is CAplus.

A stereoselective synthesis of the macrolactone core I of neopeltolide is described. The tetrahydropyran moiety was constructed via the intramol. allylation of an α-acetoxy ether. A late-stage macrolactonization provided a known synthetic intermediate of neopeltolide.

Tetrahedron Letters published new progress about 99438-28-5. 99438-28-5 belongs to ethers-buliding-blocks, auxiliary class Chiral,Aliphatic cyclic hydrocarbon, name is (+)-B-Methoxydiisopinocampheylborane, and the molecular formula is C21H37BO, Category: ethers-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Tanaka, Nobuhiro published the artcileTotal synthesis of rhoiptelol B, Related Products of ethers-buliding-blocks, the publication is Heterocycles (2018), 97(2), 1157-1164, database is CAplus.

A stereoselective total synthesis of rhoiptelol B, a diarylheptanoid isolated from the fruits of Rhoiptelea chiliantha, is described. The tetrahydropyran ring was constructed via an intramol. allylation methodol.

Heterocycles published new progress about 99438-28-5. 99438-28-5 belongs to ethers-buliding-blocks, auxiliary class Chiral,Aliphatic cyclic hydrocarbon, name is (+)-B-Methoxydiisopinocampheylborane, and the molecular formula is C6H12O2, Related Products of ethers-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Bates, Roderick W. published the artcileTetrahydropyran synthesis by intramolecular conjugate addition to enones: synthesis of the clavosolide tetrahydropyran ring, Recommanded Product: (+)-B-Methoxydiisopinocampheylborane, the publication is Synthesis (2010), 2935-2942, database is CAplus.

The synthesis of a tetrahydropyran intermediate for clavosolide A is reported, employing a combination of cross-metathesis and intramol. oxa-Michael addition The intramol. oxa-Michael addition to α,β-unsaturated esters requires the use of strong bases and can result in either modest yields or stereo-isomeric mixtures, and can be highly variable according to the substrate structure. In contrast, the corresponding ketones cyclize under very mild conditions to give the 2,6-cis-isomers directly. The use of appropriately substituted ketones allows efficient conversion into esters.

Synthesis published new progress about 99438-28-5. 99438-28-5 belongs to ethers-buliding-blocks, auxiliary class Chiral,Aliphatic cyclic hydrocarbon, name is (+)-B-Methoxydiisopinocampheylborane, and the molecular formula is C21H37BO, Recommanded Product: (+)-B-Methoxydiisopinocampheylborane.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Hirner, Sebastian published the artcileMicrowave-assisted rearrangement of vinylaziridines to 3-pyrrolines: formal synthesis of (-)-anisomycin, Safety of (+)-B-Methoxydiisopinocampheylborane, the publication is Synlett (2005), 3099-3102, database is CAplus.

An efficient microwave-assisted rearrangement of activated vinylaziridines to 3-pyrrolines is described. The rearrangement proceeds in good to excellent yields and is mediated by NaI or LiI in MeCN at elevated temperatures The synthetic utility of this reaction is shown in an efficient formal total synthesis of the antibiotic (-)-anisomycin.

Synlett published new progress about 99438-28-5. 99438-28-5 belongs to ethers-buliding-blocks, auxiliary class Chiral,Aliphatic cyclic hydrocarbon, name is (+)-B-Methoxydiisopinocampheylborane, and the molecular formula is C21H37BO, Safety of (+)-B-Methoxydiisopinocampheylborane.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

De Rosa, Margherita published the artcileA three-step and enantioselective synthesis of (-)-(S)- or (+)-(R)-2-(furan-3-yl)-3,6-dihydro-2H-pyrans, HPLC of Formula: 99438-28-5, the publication is Tetrahedron Letters (2000), 41(10), 1593-1596, database is CAplus.

Enantiomerically enriched (3-furyl)-2-pyran derivatives, e.g. I, key-intermediates in the synthesis of the pharmacophoric pyranofuranone system of the bioactive natural products manoalide and cacospongionolide B, are easily accessible by a rapid sequence involving a chiral allylation and a ring closing metathesis reaction.

Tetrahedron Letters published new progress about 99438-28-5. 99438-28-5 belongs to ethers-buliding-blocks, auxiliary class Chiral,Aliphatic cyclic hydrocarbon, name is (+)-B-Methoxydiisopinocampheylborane, and the molecular formula is C21H37BO, HPLC of Formula: 99438-28-5.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Dinh, Tam Q. published the artcileAnalogs Incorporating trans-4-Hydroxy-L-proline That Reverse Multidrug Resistance Better than Hapalosin, Recommanded Product: (+)-B-Methoxydiisopinocampheylborane, the publication is Journal of Organic Chemistry (1997), 62(4), 790-791, database is CAplus.

Hydroxyproline-containing hapalosin analogs I [R = H, CH₂C₆H₄OMe (PMB); R¹ = H, CONHCH₂Ph] were prepared in several steps starting from trans-4-hydroxy-L-proline. Whereas the PMB ether of hapalosin possesses substantially lower lower anti-multidrug resistance activity than hapalosin, analogs I (R = PMB, R¹ = H; R = H, R¹ = CONHCH₂Ph) reverse multidrug resistance better than hapalosin, while I (R = = R¹ = H; R = PMB, R¹ = CONHCH₂Ph) were less effective that hapalosin. These results suggest that a free hydroxyl and an aromatic group may be important in the multidrug resistance activity of hapalosin and its analogs.

Journal of Organic Chemistry published new progress about 99438-28-5. 99438-28-5 belongs to ethers-buliding-blocks, auxiliary class Chiral,Aliphatic cyclic hydrocarbon, name is (+)-B-Methoxydiisopinocampheylborane, and the molecular formula is C21H37BO, Recommanded Product: (+)-B-Methoxydiisopinocampheylborane.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Barrett, Anthony G. M. published the artcileB-[(E)-3-(Diphenylamino)allyl]diisopinocampheylborane: an excellent reagent for the stereoselective synthesis of anti-β-diphenylamino alcohols, Category: ethers-buliding-blocks, the publication is Journal of the Chemical Society, Chemical Communications (1993), 339-41, database is CAplus.

Anti-β-Amino alcs. have been produced with high relative and absolute stereochem. control in a simple one-pot process via the reaction of aldehydes with B-[(E)-3-(diphenylamino)allyl]diisopinocampheylborane and alk. hydrogen peroxide work-up.

Journal of the Chemical Society, Chemical Communications published new progress about 99438-28-5. 99438-28-5 belongs to ethers-buliding-blocks, auxiliary class Chiral,Aliphatic cyclic hydrocarbon, name is (+)-B-Methoxydiisopinocampheylborane, and the molecular formula is C21H37BO, Category: ethers-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Barrett, Anthony G. M. published the artcileThe use of B-[(E)-3-(diphenylamino)allyl]diisopinocampheylborane as a reagent for the stereoselective synthesis of anti-β-diphenylamino alcohols and trans-1-diphenylamino-2-(1-hydroxylalkyl)cyclopropanes, Formula: C21H37BO, the publication is Tetrahedron (1993), 49(36), 7857-70, database is CAplus.

Anti-β-Amino alcs., e.g. (3R,4S)-4-(diphenylamino)-1,5-hexadien-3-ol (I), and trans-1-amino-2-(1-hydroxyalkyl)cyclopropanes, e.g. II, were prepared with high relative and absolute stereocontrol in a simple one-pot process via the reaction of aldehydes with B-[(E)-3-(diphenyamino)allyl]-diisopinocampheylborane and a subsequent alk. hydrogen peroxide work-up. The crystal structures of Mosher ester of I and cyclopropane II were determined

Tetrahedron published new progress about 99438-28-5. 99438-28-5 belongs to ethers-buliding-blocks, auxiliary class Chiral,Aliphatic cyclic hydrocarbon, name is (+)-B-Methoxydiisopinocampheylborane, and the molecular formula is C21H37BO, Formula: C21H37BO.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Zhang, Yuan published the artcileTotal Synthesis of Brevenal, Name: (+)-B-Methoxydiisopinocampheylborane, the publication is Journal of the American Chemical Society (2011), 133(9), 3208-3216, database is CAplus and MEDLINE.

This Article describes the total synthesis of the marine ladder toxin brevenal (I) utilizing a convergent synthetic strategy. Critical to the success of this work was the use of olefinic-ester cyclization reactions and the utilization of glycal epoxides as precursors to C-C and C-H bonds.

Journal of the American Chemical Society published new progress about 99438-28-5. 99438-28-5 belongs to ethers-buliding-blocks, auxiliary class Chiral,Aliphatic cyclic hydrocarbon, name is (+)-B-Methoxydiisopinocampheylborane, and the molecular formula is C7H5ClN2S, Name: (+)-B-Methoxydiisopinocampheylborane.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem