Category: 93-04-9

On June 8, 2021, Wang, Tao; Hoffmann, Marvin; Dreuw, Andreas; Hasagic, Edina; Hu, Chao; Stein, Philipp M.; Witzel, Sina; Shi, Hongwei; Yang, Yangyang; Rudolph, Matthias; Stuck, Fabian; Rominger, Frank; Kerscher, Marion; Comba, Peter; Hashmi, A. Stephen K. published an article.Formula: C11H10O The title of the article was A Metal-Free Direct Arene C-H Amination. And the article contained the following:

Here, a metal-free arene e.g., mesitylene C-H amination using hydroxylamine derivatives 4-(CH3)C6H5S(O)2ON(R)R1 (R = H, Me; R1 = Me, Boc, Bn, etc.) under benign conditions was reported. A charge transfer interaction between the aminating reagents and the arene substrates enables the chemoselective amination of the arene, even in the presence of various functional groups. Oxygen was crucial for an effective conversion and its accelerating role for the electron transfer step was proven exptl. In addition, this was rationalized by a theor. study which indicated the involvement of a dioxygen-bridged complex with a “Sandwich-like” arrangement of the aromatic starting materials and the aminating agents at the dioxygen mol. The experimental process involved the reaction of 2-Methoxynaphthalene(cas: 93-04-9).Formula: C11H10O

The Article related to aryl amine preparation chemoselective, arene hydroxylamine amination, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Amines, Amine Oxides, Imines, and Quaternary Ammonium Compounds and other aspects.Formula: C11H10O

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On May 21, 2021, Singh, Bhagat; Ahmed, Jasimuddin; Biswas, Amit; Paira, Rupankar; Mandal, Swadhin K. published an article.Synthetic Route of 93-04-9 The title of the article was Reduced Phenalenyl in Catalytic Dehalogenative Deuteration and Hydrodehalogenation of Aryl Halides. And the article contained the following:

Dehalogenative deuteration reactions are generally performed through metal-mediated processes. This report demonstrates a mild protocol for hydrodehalogenation and dehalogenative deuteration of aryl/heteroaryl halides (39 examples) using a reduced odd alternant hydrocarbon phenalenyl under transition metal-free conditions and has been employed successfully for the incorporation of deuterium in various biol. active compounds The combined approach of exptl. and theor. studies revealed a single electron transfer-based mechanism. The experimental process involved the reaction of 2-Methoxynaphthalene(cas: 93-04-9).Synthetic Route of 93-04-9

The Article related to aryl heteroaryl halide deuteration hydrodehalogenation, Heterocyclic Compounds (More Than One Hetero Atom): Fused-Ring Systems With Two Or More Hetero Atoms, No More Than One Hetero Atom Per Ring and other aspects.Synthetic Route of 93-04-9

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Becerra-Martinez, Elvia; Perez-Hernandez, Nury; Sanchez-Zavala, Maricruz; Melendez-Rodriguez, Myriam; Aristeo-Dominguez, Alberto; Suarez-Castillo, Oscar R.; Joseph-Nathan, Pedro published an article in 2022, the title of the article was Equilibrating magnetic dispersion and magnet homogeneity for the high-resolution proton nuclear magnetic resonance of monosubstituted naphthalenes.Recommanded Product: 2-Methoxynaphthalene And the article contains the following content:

Accurate chem. shift and coupling constant for 1- and 2-naphthyl derivatives were decipher by iterative full spin anal. Each of the seven magnetically nonequivalent H2-H8 atoms in 1-naphthyl derivatives, or of the H1, H3-H8 atoms in 2-naphthyl derivatives were unambiguously identified by analyzing their intra- and inter-ring coupling constants at 300 MHz and by two-dimensional homo- and heteronuclear experiments at 750 MHz. 13C chem. shifts were also determined during this study, from where some literature ambiguities were resolved using long-range C-H correlations at 750 MHz. The complete proton NMR parameters are herein ascribed for the first time. The experimental process involved the reaction of 2-Methoxynaphthalene(cas: 93-04-9).Recommanded Product: 2-Methoxynaphthalene

The Article related to naphthalene substituent effect carbon nmr, Physical Organic Chemistry: Resonance Spectra (Electron Spin, Nuclear Magnetic and Fourier Transform Nuclear Magnetic, Quadrupole, etc.) and other aspects.Recommanded Product: 2-Methoxynaphthalene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Lu, Qixing; Wang, Tao; Wu, Qian; Cheng, Lijing; Luo, Han; Liu, Lei; Chu, Guobiao; Wang, Lufeng; Li, Baosheng published an article in 2022, the title of the article was C-H heteroarylation of aromatics via catalyst free SN2′ coupling cycloaromatization.Quality Control of 2-Methoxynaphthalene And the article contains the following content:

The construction of a carbon-carbon bond is the most fundamental aspect of synthetic chem. In this study, authors developed a catalyst-free SN2′ reaction of β-OTf-substituted enamides with aromatics to obtain aryl-substituted aza-1,4-dicarbonyl compounds that can be in situ transformed into aryl-imidazole, aryl-thiazole, and aryl-oxazole in one-pot operation, thus achieving C-H heteroarylation of aromatics This simple, efficient, clean and scalable strategy, which provides difficult-to-realize biaryl products, is compatible with various aromatics having varying complexities. This method can be used for the late-stage modification of various com. pharmaceuticals or functional materials and offers an orthogonal approach for constructing biaryl compounds The experimental process involved the reaction of 2-Methoxynaphthalene(cas: 93-04-9).Quality Control of 2-Methoxynaphthalene

The Article related to aromatic compound heteroarylation coupling cycloaromatization, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Amides, Amidines, Imidic Esters, Hydrazides, and Hydrazonic Esters and other aspects.Quality Control of 2-Methoxynaphthalene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Pan, Wenjing; Li, Chenchen; Zhu, Haoyin; Li, Fangfang; Li, Tao; Zhao, Wanxiang published an article in 2021, the title of the article was A mild and practical method for deprotection of aryl methyl/benzyl/allyl ethers with HPPh2 and tBuOK.Safety of 2-Methoxynaphthalene And the article contains the following content:

A general method for the demethylation, debenzylation, and deallylation of aryl ethers ROMe (R = C6H5, 3-FC6H4, 2-naphthyl, etc.), R1OCH2Ph (R1 = C6H5, 5,6,7,8-tetrahydronaphthalen-2-yl, 2-naphthyl, etc.) and R2OCH2CH=CH2 (R2 = C6H5, 2,3-dimethylphenyl, 1-naphthyl, etc.) using HPPh2 and tBuOK is reported. The reaction features mild and metal-free reaction conditions, broad substrate scope, good functional group compatibility, and high chem. selectivity towards aryl ethers over aliphatic structures. Notably, this approach is competent to selectively deprotect the allyl or benzyl group, making it a general and practical method in organic synthesis. The experimental process involved the reaction of 2-Methoxynaphthalene(cas: 93-04-9).Safety of 2-Methoxynaphthalene

The Article related to phenol preparation, aryl methyl ether demethylation, benzyl ether preparation debenzylation, allyl ether preparation deallylation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Phenols, Thiophenols, and Derivatives Including Phenol and Thiophenol Ethers and Esters and other aspects.Safety of 2-Methoxynaphthalene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On June 22, 2021, Misal, Balu; Palav, Amey; Ganwir, Prerna; Chaturbhuj, Ganesh published an article.COA of Formula: C11H10O The title of the article was Sulfated polyborate-H2O assisted tunable activation of N-iodosuccinimide for expeditious mono and diiodination of arenes. And the article contained the following:

Owing to both Lewis and Bronsted acid active sites on sulfated polyborate under homogeneous conditions, iodination protocol of arenes was developed, which can meet the requirement of regioselectivity and higher yield. The sulfated polyborate activated N-iodosuccinimide for mono iodination of highly activated substrates viz. phenols, anilines under anhydrous condition. Water tuned sulfated polyborate to generate more Bronsted acid sites resulting in rapid activation of NIS for diiodination. The protocol was equally applicable to diiodination of 4-hydroxyphenylacetic acid to synthesize 4-hydroxy-3,5-diiodophenylacetic acid, an intermediate of tiratricol, a thyroid treatment drug. This protocol was further integrated via one-pot sequential iodination and Sonogashira coupling to synthesize aryl acetylenes, building blocks for the synthesis of a variety of specialty chems., API and natural products. The experimental process involved the reaction of 2-Methoxynaphthalene(cas: 93-04-9).COA of Formula: C11H10O

The Article related to arene iodosuccinimide sulfated polyborate catalyst regioselective iodination, iodoarene preparation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Phenols, Thiophenols, and Derivatives Including Phenol and Thiophenol Ethers and Esters and other aspects.COA of Formula: C11H10O

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Shigeno, Masanori; Hayashi, Kazutoshi; Korenaga, Toshinobu; Nozawa-Kumada, Kanako; Kondo, Yoshinori published an article in 2022, the title of the article was Organic superbase t-Bu-P4-catalyzed demethylations of methoxyarenes.Related Products of 93-04-9 And the article contains the following content:

The organic superbase t-Bu-P4 catalyzes the demethylation reactions of methoxyarenes ROMe [R = 4-cyanophenyl, 1-oxo-2,3-dihydro-1H-inden-5-yl, 1-benzothiophen-5-yl, etc.] in the presence of alkanethiol and hexamethyldisilazane was reported. The system can efficiently convert a variety of substrates, including electron-deficient, -neutral, and -rich substrates and heteroaromatic substrates, and displays excellent functional group tolerance. Computational studies show that the high reactivity achieved by t-Bu-P4 is due to the formation of the nucleophilic naked thiolate species. The experimental process involved the reaction of 2-Methoxynaphthalene(cas: 93-04-9).Related Products of 93-04-9

The Article related to hydroxyarene preparation dft study, methoxyarene demethylation organic superbase catalyst, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Phenols, Thiophenols, and Derivatives Including Phenol and Thiophenol Ethers and Esters and other aspects.Related Products of 93-04-9

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On May 15, 2020, Wang, Jing-Hao; Lei, Tao; Wu, Hao-Lin; Nan, Xiao-Lei; Li, Xu-Bing; Chen, Bin; Tung, Chen-Ho; Wu, Li-Zhu published an article.Computed Properties of 93-04-9 The title of the article was Thiol Activation toward Selective Thiolation of Aromatic C-H Bond. And the article contained the following:

An effective model for regioselective thiolation of the aromatic C-H bond by thiol activation instead of arene activation was disclosed. This method was applied into anisole derivatives that are not available in the arene activation approach to forge a single thioether isomer with high reactivity. The experimental process involved the reaction of 2-Methoxynaphthalene(cas: 93-04-9).Computed Properties of 93-04-9

The Article related to thiophenol aryl ether regioselective electrochem thiolation, diaryl thioether preparation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Phenols, Thiophenols, and Derivatives Including Phenol and Thiophenol Ethers and Esters and other aspects.Computed Properties of 93-04-9

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On November 8, 2021, Deolka, Shubham; Govindarajan, Ramadoss; Khaskin, Eugene; Fayzullin, Robert R.; Roy, Michael C.; Khusnutdinova, Julia R. published an article.Quality Control of 2-Methoxynaphthalene The title of the article was Photoinduced Trifluoromethylation of Arenes and Heteroarenes Catalyzed by High-Valent Nickel Complexes. And the article contained the following:

Authors describe a series of air-stable NiIII complexes supported by a simple, robust naphthyridine-based ligand. Access to the high-valent oxidation state is enabled by the CF3 ligands on the nickel, while the naphthyridine exhibits either a monodentate or bidentate coordination mode that depends on the oxidation state and sterics, and enables facile aerobic oxidation of NiII to NiIII. These NiIII complexes act as efficient catalysts for photoinduced C(sp2)-H bond trifluoromethylation reactions of (hetero)arenes using versatile synthetic protocols. This blue LED light-mediated catalytic protocol proceeds via a radical pathway and demonstrates potential in the late-stage functionalization of drug analogs. The experimental process involved the reaction of 2-Methoxynaphthalene(cas: 93-04-9).Quality Control of 2-Methoxynaphthalene

The Article related to arene heteroarene photoinduced trifluoromethylation high valent nickel complex, c−h bond functionalization, nickel, photoreactivity, radical formation, trifluoromethylation and other aspects.Quality Control of 2-Methoxynaphthalene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Xu, Ren-Rui; Wen, Dan; Qi, Xinxin; Wu, Xiao-Feng published an article in 2022, the title of the article was Palladium-catalyzed cascade Heck-type cyclization and reductive aminocarbonylation for the synthesis of functionalized amides.Recommanded Product: 2-Methoxynaphthalene And the article contains the following content:

A palladium-catalyzed Heck/carbonylative cyclization process was explored for the synthesis of functionalized amides. By using nitroarenes as readily accessible nitrogen sources, a variety of amide products, e.g., I (Ar = 4-MeC6H4, 2-ClC6H4, 1-naphthyl, 2-thienyl, 8-quinolinyl, etc.), was obtained from the corresponding o-iodoaryl alkenes, e.g., II, in moderate to excellent yields with good functional group compatibility. Furthermore, a late-stage modification of a natural mol. was also achieved by this protocol. The experimental process involved the reaction of 2-Methoxynaphthalene(cas: 93-04-9).Recommanded Product: 2-Methoxynaphthalene

The Article related to amide benzopyran benzofuran preparation, alkenyl iodobenzene tandem heck cyclization aminocarbonylation nitroarene palladium catalyst, Heterocyclic Compounds (One Hetero Atom): Benzopyrans (Including Coumarins, Isocoumarins, Chromones, Benzopyrones, Dibenzopyrans, and Other Arenopyrans) and other aspects.Recommanded Product: 2-Methoxynaphthalene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem