Category: 91-16-7

Berkowitz, Alex J. published the artcileSynthesis of α-Tropolones through Autoxidation of Dioxole-Fused Cycloheptatrienes, Name: 1,2-Dimethoxybenzene, the publication is Journal of Organic Chemistry (2022), 87(7), 4499-4507, database is CAplus and MEDLINE.

Herein, we describe the formation of tropolones through the autoxidation of Buchner reaction-derived cycloheptatrienes. The reaction is exceptionally simple procedurally, as it involves blowing a stream of compressed air over the cycloheptatriene, and the products can be obtained without any need for chromatog. The chem. works specifically on dioxolane-fused systems or close variants, and substitution patterns are also important. A radical-based mechanistic hypothesis is put forward to explain these results. Finally, we demonstrate the utility of the overall process in the synthesis of amide-appended tropolones and an isomer of stipitatic acid.

Journal of Organic Chemistry published new progress about 91-16-7. 91-16-7 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether,Inhibitor,Inhibitor,Inhibitor, name is 1,2-Dimethoxybenzene, and the molecular formula is C8H10O2, Name: 1,2-Dimethoxybenzene.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

De Flaviis, Riccardo published the artcileQuantitatively unravelling the effect of altitude of cultivation on the volatiles fingerprint of wheat by a chemometric approach, Recommanded Product: 1,2-Dimethoxybenzene, the publication is Food Chemistry (2022), 131296, database is CAplus and MEDLINE.

The cultivation of crops at high elevations in response to climate changes leads to modifications in the volatile organic compounds (VOCs) profile. The VOCs profile of common and durum wheat grown in different fields sited at three different elevations over two years was analyzed. Partial least square anal. (PLS2) evidenced the effect of altitude on VOCs variance that was hidden among others (cultivation year, species, farm) not correlated with it. PLS1 anal. was further carried out using VOCs as explanatory variables and altitude as dependent variable to find the linear combination of VOCs able to continuously predict the altitude of samples. Selected VOCs, related to biotic, abiotic and oxidative stress conditions, could describe the changes in VOCs profile of wheat induced by altitude increase. Furthermore, common and durum wheat showed different responses to stress at high altitude. These results could be considerably useful for wheat product classification and authentication.

Food Chemistry published new progress about 91-16-7. 91-16-7 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether,Inhibitor,Inhibitor,Inhibitor, name is 1,2-Dimethoxybenzene, and the molecular formula is C8H10O2, Recommanded Product: 1,2-Dimethoxybenzene.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

De Flaviis, Riccardo published the artcileCould environmental effect overcome genetic A chemometric study on wheat volatiles fingerprint, Application In Synthesis of 91-16-7, the publication is Food Chemistry (2022), 131236, database is CAplus and MEDLINE.

A deeper knowledge of the causes of volatile organic compounds (VOCs) variance in wheat is crucial for quality improvement and control of its derivatives The VOCs profile of common and durum wheat kernels grown in different fields sited at different altitudes over two years was analyzed and 149 compounds were identified by gas chromatog.-mass spectrometry. Principal component anal. evidenced that the year of cultivation was the highest source of VOCs variance. The effects of wheat origin, as described by the cultivation site, its elevation, and species were further investigated by PLS-DA, that permitted to correctly classify wheat of different origin on the basis of its VOCs profile. The importance of the different effects was investigated by multidimensional test and resulted: year of cultivation > field of cultivation > species > altitude. Findings suggest that environmental conditions are more important than species in the determination of the VOCs variance of wheat.

Food Chemistry published new progress about 91-16-7. 91-16-7 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether,Inhibitor,Inhibitor,Inhibitor, name is 1,2-Dimethoxybenzene, and the molecular formula is C8H10O2, Application In Synthesis of 91-16-7.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Marrot, Laetitia published the artcileCharacterization of the compounds released in the gaseous waste stream during the slow pyrolysis of hemp (Cannabis sativa L.), Recommanded Product: 1,2-Dimethoxybenzene, the publication is Molecules (2022), 27(9), 2794, database is CAplus and MEDLINE.

This study aims to characterize and valorize hemp residual biomass by a slow pyrolysis process. The volatile byproducts of hemp carbonization were characterized by several methods (TGA, UV-VIS, TLC, Flash Prep-LC, UHPLC, QTOF-MS) to understand the pyrolysis reaction mechanisms and to identify the chem. products produced during the process. The obtained carbon yield was 29%, generating a gaseous stream composed of phenols and furans which was collected in four temperature ranges (F1 at 20-150°C, F2 at 150-250°C, F3 at 250-400°C and F4 at 400-1000°C). The obtained liquid fractions were separated into subfractions by flash chromatog. The total phenolic content (TPC) varied depending on the fraction but did not correlate with an increase in temperature or with a decrease in pH value. Compounds present in fractions F1, F3 and F4, being mainly phenolic mols. such as guaiacyl or syringyl derivatives issued from the lignin degradation, exhibit antioxidant capacity. The temperature of the pyrolysis process was pos. correlated with detectable phenolic content, which can be explained by the decomposition order of the hemp chem. constituents. A detailed understanding of the chem. composition of pyrolysis products of hemp residuals allows for an assessment of their potential valorization routes and the future economic potential of underutilized biomass.

Molecules published new progress about 91-16-7. 91-16-7 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether,Inhibitor,Inhibitor,Inhibitor, name is 1,2-Dimethoxybenzene, and the molecular formula is C8H10O2, Recommanded Product: 1,2-Dimethoxybenzene.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Zheng, Jie published the artcileSynthesis of Antimicrobial Benzo[1,2,4]triazoloazepinium Salts and Tetrahydronaphtho[1,2-e][1,2,4]triazines by Polar [3⁺ + 2] and [4 + 2]-Cycloaddition Reactions, Quality Control of 91-16-7, the publication is Journal of Organic Chemistry (2022), 87(1), 464-478, database is CAplus and MEDLINE.

Novel annulated azaheterocycles of benzo[1,2,4]triazoloazepine and tetrahydronaphtho[1,2-e][1,2,4]triazine derivatives have been synthesized. Treatment of 2-diazenyl-1,2,3,4-tetrahydronaphthalen-2-yl acetates with BF₃·Et₂O generates 1-aza-2-azoniaallenium cation intermediates (or azocarbenium ions), which are intercepted by nitriles via cascade polar [3⁺ + 2]-cycloaddition/rearrangement reactions to afford benzo[1,2,4]triazoloazepinium salts. These literature unprecedented fused tricycle compounds have been shown to exhibit antimicrobial activity against Gram-pos. Staphylococcus aureus with in silico docking studies, suggesting that they may exhibit their antibiotic activity through inhibition of DNA gyrase. Addnl., when Et 2-(1-acetoxy-1,2,3,4-tetrahydronaphthalen-2-yl)diazene-1-carboxylate is employed, the reaction with BF₃·Et₂O produces 1,2-diaza-1,3-diene, which reacts with nitriles via a diaza-Diels-Alder reaction with inverse electron demand, leading to Et tetrahydronaphtho[1,2-e][1,2,4]triazine carboxylates. The DFT calculation has been performed to further prove the D-A reaction speculation.

Journal of Organic Chemistry published new progress about 91-16-7. 91-16-7 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether,Inhibitor,Inhibitor,Inhibitor, name is 1,2-Dimethoxybenzene, and the molecular formula is C20H40O2, Quality Control of 91-16-7.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Sangjan, Worasit published the artcileIdentification of volatile biomarkers for high-throughput sensing of soft rot and Pythium leak diseases in stored potatoes, Recommanded Product: 1,2-Dimethoxybenzene, the publication is Food Chemistry (2022), 130910, database is CAplus and MEDLINE.

Soft rot and Pythium leak are postharvest storage diseases of potato tubers that can cause substantial crop losses in the US. This study focused on detecting volatile organic compounds (VOCs) associated with rot inoculated tubers during storage (up to 21 days) using headspace solid-phase microextraction (SPME) coupled to gas chromatog. (GC) with mass spectrometry (MS) and flame ionization detector (FID) anal. Russet Burbank and Ranger Russet tubers were inoculated with the rot pathogens. Static sampling with 50 min trapping time followed by GC-MS and GC-FID anal. identified 23 and 30 common VOCs from the pathogen inoculated tubers. Overall, n,n-dimethylmethylamine, acetone, 1-undecene, and styrene, occurred frequently and repeatability in inoculated samples based on GC-MS anal., with the latter two found using GC-FID anal. as well. Identification of such biomarkers can be useful in developing high-throughput VOC sensing systems for early disease detection in potato storage facilities.

Food Chemistry published new progress about 91-16-7. 91-16-7 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether,Inhibitor,Inhibitor,Inhibitor, name is 1,2-Dimethoxybenzene, and the molecular formula is C8H10O2, Recommanded Product: 1,2-Dimethoxybenzene.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Grishin, Igor Yu. published the artcileA sequence of acylamination and acylation reactions in polyphosphoric acid – a novel approach to the Friedlander synthesis of 2-arylquinolines, Formula: C8H10O2, the publication is Chemistry of Heterocyclic Compounds (New York, NY, United States) (2022), 58(6-7), 313-318, database is CAplus.

A method for the synthesis of 2-(2-acylaminoaryl)quinolines I (R¹ = OMe, -OCH₂CH₂O-, Me; R² = Me, Et) was developed based on a one-pot sequence of direct electrophilic acylamination of arenes with nitroalkanes R²NO₂ in polyphosphoric acid and acylation at the ortho position with respect to the acylamino group.

Chemistry of Heterocyclic Compounds (New York, NY, United States) published new progress about 91-16-7. 91-16-7 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether,Inhibitor,Inhibitor,Inhibitor, name is 1,2-Dimethoxybenzene, and the molecular formula is C8H10O2, Formula: C8H10O2.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Torrens, Aidan A. published the artcileRapid and Mild Cleavage of Aryl-Alkyl Ethers to Liberate Phenols, Recommanded Product: 1,2-Dimethoxybenzene, the publication is European Journal of Organic Chemistry (2022), 2022(27), e202200570, database is CAplus.

The Piers-Rubinsztajn reaction enables rapid deprotection of aryl alkyl ethers under ambient conditions was reported. This chem. leverages tris(pentafluorophenyl)borane and silyl hydrides to convert aryl Me ethers to siloxanes, which can then be cleaved using 1 % HCl in EtOH. Authors examined 26 derivatives and routinely obtained yields >85 %, even in the presence of sterically demanding groups and complex substrate structures. Other alkyl ethers including Et, Pr, iso-Pr, tert-Bu, and benzyl groups were also easily removed.

European Journal of Organic Chemistry published new progress about 91-16-7. 91-16-7 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether,Inhibitor,Inhibitor,Inhibitor, name is 1,2-Dimethoxybenzene, and the molecular formula is C25H34N4O2S, Recommanded Product: 1,2-Dimethoxybenzene.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Divya, R. published the artcileSynthesis, experimental and computational characterizations of 8,9-dimethoxybenzo[b]naphtho[2,3-d] thiophene (DBNT) crystals for electro-mechano utilities, Recommanded Product: 1,2-Dimethoxybenzene, the publication is Inorganic Chemistry Communications (2022), 109249, database is CAplus.

Single crystals of organic nonlinear optical material, 8,9-Dimethoxybenzo[b]naphtho[2,3-d] thiophene (DBNT) are need to grow as the titled crystals have thiophene, since thiophenes are having potential bio activity and industrial uses. The entitled specimen is well-grown by solution growth method and reported for the first time for computational and exptl. study. Characterization of the crystals is made using single crystal x-ray diffraction and compared for the elucidation of structure of DBNT for bond parameters. The titled compound is having the chem. formula C₁₈H₁₄O₂S. From the structure, the planar rings are properly identified. The crystal system of DBNT is monoclinic in nature and the space group is P2₁/n. The lattice constants are 13.0063 Å, 5.9632 Å and 18.3802 Å and β is 104.020° which is determined by XRD anal. The nonlinear optical – NLO characteristics of this material is analyzed and is used for opto-electronic gadgets and filters because of its nonlinearities and in exptl. frequency doubling circuits. The composition of elements present in the grown specimen of DBNT crystal was theor. and exptl. analyzed. The morphol. effect of DBNT is analyzed and reported for the surfaces of crystal with magnifications and the dielec. behavior was studied properly for all polarizations and reported for entitled crystalline DBNT material, in mechano use by preloading data as coated DBNT. The dielec. and crystalline nature of the specimen is by elec. correlation and the thin film influx refers the proper grown confirmation of the DBNT and encompasses the filter usage exclusively of opto-electronic way.

Inorganic Chemistry Communications published new progress about 91-16-7. 91-16-7 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether,Inhibitor,Inhibitor,Inhibitor, name is 1,2-Dimethoxybenzene, and the molecular formula is C8H10O2, Recommanded Product: 1,2-Dimethoxybenzene.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Singh, Sanjay published the artcileDevelopment of Transition-Metal-Free Lewis Acid-Initiated Double Arylation of Aldehyde: A Facile Approach Towards the Total Synthesis of Anti-Breast-Cancer Agent, Recommanded Product: 1,2-Dimethoxybenzene, the publication is Chemistry – A European Journal (2022), 28(14), e202104545, database is CAplus and MEDLINE.

This work describes a mild and robust double hydroarylation strategy for the synthesis of sym. /unsym. diaryl- and triarylmethanes in excellent yields using Lambert salt (0.2-1.0 mol%). Despite the anticipated challenges associated with controlling selective product formation, unsym. diaryl- and triarylmethanes products are obtained unprecedentedly. A highly efficient gram scale reaction has also been reported (TON for sym. product=475 and for unsym. product=390). The synthetic utility of the methodol. is demonstrated by the preparation of several unexplored diaryl- and triarylmethane-based biol. relevant mols., such as arundine, vibrindole A, turbomycin B, and certain anti-inflammatory agents. A total synthesis of an anti-breast-cancer agent is also demonstrated. Control experiments, Hammett anal., HRMS and GC-MS studies reveal the reaction intermediates and reaction mechanism.

Chemistry – A European Journal published new progress about 91-16-7. 91-16-7 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether,Inhibitor,Inhibitor,Inhibitor, name is 1,2-Dimethoxybenzene, and the molecular formula is C13H18BBrO3, Recommanded Product: 1,2-Dimethoxybenzene.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem