Related Products of 887268-25-9, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 887268-25-9, name is 2-Bromo-4-methyl-1-(trifluoromethoxy)benzene belongs to ethers-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
1-Bromo-5-methyl-2-trifluoromethoxybenzene (1.0 g, 3.92 mmol), bis(pinacolato)diboron (1.49 g, 5.88 mmol), potassium acetate (1.54 g, 15.7 mmol) and 1 ,1′-[bis(diphenylphosphino)ferrocene] dichloropalladium (II) (0.287 g, 0.392 mmol) were combined and stirred in dimethylsulphoxide (25 ml). The reaction flask was purged with nitrogen for 5 minutes before heating to 1000C for 10 hours. The mixture was cooled and partitioned between f¡ãrt-butylmethyl ether (100 ml) and water (100 ml). Insoluble material was removed by filtration then the organic extract dried
The synthetic route of 2-Bromo-4-methyl-1-(trifluoromethoxy)benzene has been constantly updated, and we look forward to future research findings.
Reference:
Patent; PFIZER LIMITED; WO2008/135826; (2008); A2;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem