Category: 673-22-3

In 2022,Kuhne, Irina A.; Ozarowski, Andrew; Sultan, Aizuddin; Esien, Kane; Carter, Anthony B.; Wix, Paul; Casey, Aoife; Heerah-Booluck, Mooneerah; Keene, Tony D.; Muller-Bunz, Helge; Felton, Solveig; Hill, Stephen; Morgan, Grace G. published an article in Inorganic Chemistry. The title of the article was 《Homochiral Mn3+ Spin-Crossover Complexes: A Structural and Spectroscopic Study》.Recommanded Product: 673-22-3 The author mentioned the following in the article:

Structural, magnetic and spectroscopic data on a Mn3+ spin crossover complex with Schiff base ligand 4-OMe-Sal2323, isolated in crystal lattices with five different counteranions, are reported. Complexes of [Mn(4-OMe-Sal2323)]X where X = ClO4- (1), BF4- (2), NO3- (3), Br- (4) and I- (5) crystallize isotypically in the chiral orthorhombic space group P21212 with a range of spin state preferences for the [Mn(4-OMe-Sal2323)]+ complex cation over the temperature range 5-300 K. Complexes 1 and 2 are high spin, complex 5 undergoes a gradual and complete thermal spin crossover, while complexes 3 and 4 show stepped crossovers with different ratios of spin triplet and quintet forms in the intermediate temperature range. High field ESR was used to measure the zero-field splitting parameters associated with the spin triplet and quintet states at temperatures below 10 K for complexes 4 and 2 with resp. values: Ds=1 = +23.38(1) cm-1, ES=1 = +2.79(1) cm-1 and DS=2 = +6.9(3) cm-1, with a distribution of E parameters for the S = 2 state. Solid state CD (CD) spectra on high spin complex 1 at room temperature reveal a 2:1 ratio of enantiomers in the chiral conglomerate, and solution CD measurements on the same sample in methanol show that it is stable toward racemization. Solid state UV-vis absorption spectra on high spin complex 1 and mixed S = 1/S = 2 sample 5 reveal different intensities at higher energies, in line with the different electronic composition The statistical prevalence of homochiral crystallization of [Mn(4-OMe-Sal2323)]+ in five lattices with different achiral counterions suggests that the chirality may be directed by the 4-OMe-Sal2323 ligand. In the part of experimental materials, we found many familiar compounds, such as 2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3Recommanded Product: 673-22-3)

2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3) is the main component of root bark essential oil of Periploca sepium Bunge. It is a potential tyrosinase inhibitor present in African medicinal plants. 2-Hydroxy-4-methoxybenzaldehyde was used in the synthesis of Schiff base ligand.Recommanded Product: 673-22-3

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《Structural characterization of new zinc(II) complexes with N2O2 chelating thiosemicarbazidato ligands; investigation of the relationship between their DNA interaction and in vitro antiproliferative activity towards human cancer cells》 was published in New Journal of Chemistry in 2020. These research results belong to Kaya, Busra; Yilmaz, Zehra Kubra; Sahin, Onur; Aslim, Belma; Ulkuseven, Bahri. Computed Properties of C8H8O3 The article mentions the following:

Two new zinc(II) complexes were synthesized by condensation of 4,4,4-trifluoro-1-(2-thienyl)-1,3-butanedione-S-methyl-thiosemicarbazone with salicylaldehyde or 4-methoxy-salicylaldehyde. Structures of the N2O2-chelate complexes, Zn1 and Zn2, were explicated by IR, 1H NMR, ESI-MS and X-ray crystallog. Electronic spectral anal. was performed to assign the nature of the interaction between the complexes and calf thymus DNA (CT-DNA). DNA cleavage activities of the complexes were investigated by gel electrophoresis (pBR322 DNA). The results indicated that the complexes bind to CT-DNA via an intercalation mode and the binding of Zn2 is stronger than that of Zn1. Relatively high concentrations of the zinc complexes were found to encourage the cleavage of DNA from supercoiled form (Form I) to nicked circular form (Form II). The antiproliferative activity of the complexes was determined against human colorectal adenocarcinoma (HT-29) and human cervical carcinoma (HeLa) cell lines by MTT assay. The tests revealed that the complex Zn2 exhibited a higher antiproliferative effect than Zn1 on HT-29 and HeLa cells, analogical to the data from DNA interaction experiments The studies demonstrated that complex Zn2 could be a good candidate as a chemotherapeutic drug targeting DNA. In the experiment, the researchers used 2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3Computed Properties of C8H8O3)

2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3) is employed in the synthesis of Schiff base ligand. It is applied as a reactant in the synthesis of LPA1R antagonists used in the inhibition of LPA-induced proliferation and contraction of normal human lung fibroblasts. Also used in the synthesis of tyrosine kinase 6 proteinase inhibitors.Computed Properties of C8H8O3

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Ether – Wikipedia,
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《Population Genetics Coupled Chemical Profiling for Conservation Implications of Decalepis salicifolia (Bedd. ex Hook.f.) Venter, an Endemic and Critically Endangered Species of Western Ghats, India》 was published in Biochemical Genetics in 2020. These research results belong to Gokul, Sivaraman; Rodrigues, Vereena; Kumar, Amit; Verma, Ram S.; Shukla, Ashutosh K.; Sundaresan, Velusamy. Quality Control of 2-Hydroxy-4-methoxybenzaldehyde The article mentions the following:

Information on the genetic diversity and population structure is essential for developing conservational management programs, especially for threatened species. Decalepis salicifolia (Bedd. ex Hook.f.) Venter is a steno-endemic and critically endangered species of the south Western Ghats of India. The present study used ISSR markers as well as essential oil profiling to reveal the extent and distribution of genetic as well as the chem. diversity of all the twelve known populations of D. salicifolia. A total of 84 amplicons generated using 17 ISSR primers represented an overall 72.34% polymorphism. The highest percentage of polymorphic loci was recorded in the population of Theemalai (40.48%) and lowest in Kokanmalai (4.76%) with an average of 20.04% across all the studied populations. At the species level, the Nei’s genetic diversity observed was 0.255 ∓ 0.186, while Shannon’s information index observed was 0.385 ∓ 0.260. The genetic similarity-based unweighted pair-group method with arithmetic average dendrogram grouped the populations according to their geog. locations, which was corroborated by principal component anal. and Bayesian clustering. Distribution of genetic variance through anal. of mol. variance indicated that 38% variance resides within the population, and 62% variance resides among the populations (P < 0.001). Gas chromatog. analyses of root volatiles showed significant variation in the percent content of 2-hydroxy-4-methoxybenzaldehyde. The Mantel test analyses showed a pos. correlation between the genetic vs. geog. distances. Based on the results, both ex situ and in situ conservation strategies are suggested to maximally preserve the genetic resources of this endangered species. In the part of experimental materials, we found many familiar compounds, such as 2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3Quality Control of 2-Hydroxy-4-methoxybenzaldehyde)

2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3) is employed in the synthesis of Schiff base ligand. It is applied as a reactant in the synthesis of LPA1R antagonists used in the inhibition of LPA-induced proliferation and contraction of normal human lung fibroblasts. Also used in the synthesis of tyrosine kinase 6 proteinase inhibitors.Quality Control of 2-Hydroxy-4-methoxybenzaldehyde

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Vagh, Sandip Sambhaji; Hou, Bo-Jhih; Edukondalu, Athukuri; Wang, Pin-Ching; Lin, Wenwei published their research in Organic Letters in 2021. The article was titled 《Phosphine-Mediated MBH-Type/Acyl Transfer/Wittig Sequence for Construction of Functionalized Furo[3,2-c]coumarins》.HPLC of Formula: 673-22-3 The article contains the following contents:

A new method for the construction of functionalized furo[3,2-c]coumarins via MBH-type/acyl-transfer/Wittig reaction was reported. The current approach would open a new route for the simultaneous formation of two rings in a one-pot reaction which was accompanied by incorporation of a keto functionality on the furan ring by activating the terminal alkynoates with phosphine. Furthermore, this protocol could also be applicable to the internal alkynoates/propiolamides to generate the 2,3-disubstituted furo[3,2-c]coumarins/furo[3,2-c]quinolinones by excluding the acyl-transfer reaction. After reading the article, we found that the author used 2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3HPLC of Formula: 673-22-3)

2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3) is employed in the synthesis of Schiff base ligand. It is applied as a reactant in the synthesis of LPA1R antagonists used in the inhibition of LPA-induced proliferation and contraction of normal human lung fibroblasts. Also used in the synthesis of tyrosine kinase 6 proteinase inhibitors.HPLC of Formula: 673-22-3

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Category: ethers-buliding-blocksIn 2022 ,《Greener synthesis of pyranopyrazole derivatives catalyzed by CaO nanoparticles》 appeared in Rasayan Journal of Chemistry. The author of the article were Sangeeta; Singh, Har Lal; Chahar, Mamta; Sahal, Saloni; Khaturia, Sarita. The article conveys some information:

The development of a novel green synthetic protocol for the series of pyrano-pyrazole derivatives I (R = CN, COOEt; X = H, 4-Cl, 2-OH-4-OMe, 4-NO2, etc.) in a one-pot multi-component method using CaO nanoparticles as the heterogeneous catalyst was reported. The CaO nanoparticles were synthesized by a greener route using an economic and efficient alternative i.e. papaya leaf extract and exhibited excellent catalytic activity, and this plant-mediated synthesis of CaO nanoparticles is a very promising area of research. CaO nanoparticles can be efficiently used in the synthesis of pyrano-pyrazoles I and this catalytic approach can deliver the appropriate products in a rapid reaction time with a high yield (85-91%). The current protocol has various advantages, including a short reaction time, a high percent yield, a clean reaction, a simple separation technique, and a recoverable catalyst that retains its catalytic activity when utilized in subsequent reactions. Characterization of synthesized pyrano-pyrazole derivatives I were wdone by IR, 1H and 13C NMR spectral data as well as HOMO-LUMO calculations In the part of experimental materials, we found many familiar compounds, such as 2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3Category: ethers-buliding-blocks)

2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3) is the main component of root bark essential oil of Periploca sepium Bunge. It is a potential tyrosinase inhibitor present in African medicinal plants. 2-Hydroxy-4-methoxybenzaldehyde was used in the synthesis of Schiff base ligand.Category: ethers-buliding-blocks

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Ether – Wikipedia,
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The author of 《Visible Light-Initiated Catalyst-Free One-Pot, Multicomponent Construction of 5-Substituted Indole Chromeno[2,3-b]pyridines》 were Zhang, Mo; Chen, Meng-Nan; Zhang, Zhan-Hui. And the article was published in Advanced Synthesis & Catalysis in 2019. Category: ethers-buliding-blocks The author mentioned the following in the article:

A visible light-initiated pseudo four-component reaction of salicylaldehydes, indole and malononitrile in aqueous Et lactate is described. This pot, at. and step economic (PASE) methodol. provides a practical approach for the preparation of various 5-substituted indole chromeno[2,3-b]pyridines from readily available starting materials at ambient temperature without any catalyst. High yields and excellent functional groups tolerance are observed In the experimental materials used by the author, we found 2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3Category: ethers-buliding-blocks)

2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3) is the main component of root bark essential oil of Periploca sepium Bunge. It is a potential tyrosinase inhibitor present in African medicinal plants. 2-Hydroxy-4-methoxybenzaldehyde was used in the synthesis of Schiff base ligand.Category: ethers-buliding-blocks

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

You, Guirong; Chang, Zhi-Xin; Yan, Jizhong; Xia, Chengcai; Li, Fu-Rong; Li, Hong-Shuang published their research in Organic Chemistry Frontiers in 2021. The article was titled 《Rhodium-catalyzed sequential intermolecular hydroacylation and deconjugative isomerization toward diversified diketones》.Name: 2-Hydroxy-4-methoxybenzaldehyde The article contains the following contents:

A rhodium-catalyzed tandem intermol. hydroacylation of terminal alkyne-substituted secondary alcs. RCH(OH)(CH2)nCCH (R = Ph, thiophen-3-yl, Pr, etc.; n = 0, 1, 2) (I) with chelating aldehydes 2-OH-R1C6H3CHO (R1 = 3-CF3, 4-Cl, 5-NO2, etc.) and deconjugative isomerization of the resulting α,β-unsaturated ketones for the preparation of synthetically valuable 1,4-diketones 2-OH-R1C6H3C(O)CH2CH2C(O)R (II) is developed. Of note, the completely atom-economical protocol can be extended to the alkynyl alcs. (I) with appropriate carbon chain length, from which 1,5-diketone/1,6-diketone 2-OH-C6H4C(O)(CH2)nC(O)C6H5 (n = 3, 4) were obtained involving the short-range deconjugative isomerization. Given its robustness, broad substrate scope, and excellent regioselectivity, this approach provides a promising platform for the synthesis of diverse diketones (II). The experimental part of the paper was very detailed, including the reaction process of 2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3Name: 2-Hydroxy-4-methoxybenzaldehyde)

2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3) is employed in the synthesis of Schiff base ligand. It is applied as a reactant in the synthesis of LPA1R antagonists used in the inhibition of LPA-induced proliferation and contraction of normal human lung fibroblasts. Also used in the synthesis of tyrosine kinase 6 proteinase inhibitors.Name: 2-Hydroxy-4-methoxybenzaldehyde

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《Decalepis salicifolia (Bedd. ex Hook. f.) Venter: A steno-endemic and critically endangered medicinal and aromatic plant from Western Ghats, India.》 was written by Rodrigues, Vereena; Kumar, Amit; Gokul, Sivaraman; Shukla, Ashutosh K; Ravikumar, Kaliamoorthy; Sundaresan, Velusamy. Computed Properties of C8H8O3 And the article was included in Journal of biosciences in 2021. The article conveys some information:

Decalepis salicifolia (Bedd. ex Hook. f.) Venter is a potential medicinal and highly aromatic plant species confined to the southernmost part of the Western Ghats of India. The plant is well known for its traditional uses among the various tribal communities of south India. The tubers of the plant possess characteristic vanillin-like aroma due to the presence of the compound 2-hydroxy-4-methoxybenzaldehyde. The tubers are used to substitute Hemidesmus indicus in various herbal formulations. The plants in the wild are continuously uprooted for their roots, leading to the irreversible destruction of the whole plant. The resulting tremendous loss of populations in the wild led to the species being declared as critically endangered by IUCN. Our group is working on the various aspects of this species including population status, distribution mapping, prospection, and conservation management. In the present review, we have brought out the available information till date on D. salicifolia, including taxonomy, ethno-medicinal uses, phytochemistry, pharmacology, population status, and conservation efforts along with research gap and lacunae to provide direction for further research into this less explored medicinal and aromatic plant. After reading the article, we found that the author used 2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3Computed Properties of C8H8O3)

2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3) is employed in the synthesis of Schiff base ligand. It is applied as a reactant in the synthesis of LPA1R antagonists used in the inhibition of LPA-induced proliferation and contraction of normal human lung fibroblasts. Also used in the synthesis of tyrosine kinase 6 proteinase inhibitors.Computed Properties of C8H8O3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《Washable colorimetric nanofiber nonwoven for ammonia gas detection》 was written by Oh, Hyun Ju; Yeang, Byeong Jin; Park, Young Ki; Choi, Hyun Jung; Kim, Jong H.; Kang, Young Sik; Bae, Younghwan; Kim, Jung Yeon; Lim, Seung Ju; Lee, Woosung; Hahm, Wan-Gyu. Synthetic Route of C8H8O3This research focused onwashable colorimetric nanofiber nonwoven ammonia gas detection; ammonia gas; colorimetric nanofiber sensor; gas detection; meta-aramid nanofiber. The article conveys some information:

The colorimetric sensor is a facile, cost-effective, and non-power-operated green energy material for gas detection. In this study, the colorimetric sensing property of a meta-aramid/dye 3 nanofiber sensor for ammonia (NH3) gas detection was investigated. This colorimetric sensor was prepared using various dye 3 concentrations via electrospinning. Morphol., thermal, structural, and mech. analyses of the sensor were carried out by field-emission SEM, thermogravimetric anal., Fourier-transform IR spectroscopy, and a universal testing machine, resp. A homemade computer color matching machine connected with a gas flow device characterized the response of the meta-aramid/dye 3 nanofiber colorimetric sensor to various exposure levels of NH3 gas. From the results, we confirmed that this colorimetric green energy sensor could detect ammonia gas in the concentration of 1-10 ppm with a sensing response time of 10 s at room temperature After washing with laundry detergent for 30 min, the colorimetric sensors still exhibited sensing property and reversibility.2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3Synthetic Route of C8H8O3) was used in this study.

2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3) is the main component of root bark essential oil of Periploca sepium Bunge. It is a potential tyrosinase inhibitor present in African medicinal plants. 2-Hydroxy-4-methoxybenzaldehyde was used in the synthesis of Schiff base ligand.Synthetic Route of C8H8O3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《Synthesis, characterization and antibacterial effect of diarylmethylamine-based imines》 was published in Journal of Molecular Structure in 2020. These research results belong to Onur, Sultan; Kose, Muhammet; Kocer, Ferudun; Tumer, Ferhan. Safety of 2-Hydroxy-4-methoxybenzaldehyde The article mentions the following:

Firstly, starting from benzoic acid, the diarylmethanone compound (4-methylphenyl)(phenyl)methanone was synthesized. The diarylmethanone (4-methylphenyl)(phenyl)methanone was converted to the corresponding oxime N-[(4-methylphenyl)(phenyl)methylidene]hydroxylamine and then reduced to the diarylmethylamine compd (4-methylphenyl)(phenyl)methanamine. Four different imine compounds2-OH-3-R1-4-R2C6H2CH=NCH(4-CH3C6H5)C6H4(R1 = H, OH, OMe; R2 = H, OH, OMe) were obtained from the condensation of the (4-methylphenyl)(phenyl)methanamine with four different salicylaldehyde 2-OH-3-R1-4-R2C6H2CHO. Antimicrobial activities against Gram (+) and Gram (-) microorganisms (Staphylococcus aureus, Bacillus cereus as the Gram (+); Escherichia coli and Salmonella typhimurium as the Gram (-); and Candida albicans as the fungi) were investigated. In the experiment, the researchers used many compounds, for example, 2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3Safety of 2-Hydroxy-4-methoxybenzaldehyde)

2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3) is employed in the synthesis of Schiff base ligand. It is applied as a reactant in the synthesis of LPA1R antagonists used in the inhibition of LPA-induced proliferation and contraction of normal human lung fibroblasts. Also used in the synthesis of tyrosine kinase 6 proteinase inhibitors.Safety of 2-Hydroxy-4-methoxybenzaldehyde

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem