Category: 6052-10-4

Application of 6052-10-4, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 6052-10-4 name is 4,4′-(Ethane-1,2-diylbis(oxy))dianiline, This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.

The reatcion of 4-(4-hexyloxybenzoyloxy) benzaldehyde (22 mmol) in anhydrous EtOH(50 mL) with [1,2-bis(4-aminophenoxy)ethane (11 mmol) in the presence of PTSA[3, 21, 22]. The reaction mixture was stirred for 16 hr at the room temperature. Thecrude precipitate was collected by filtration and purified by the recrystallization of bothchloroform and ethyl acetate solvents. The prepared HBPE-1 was confirmed by 1H-NMR. 1H-NMR (CDCl3, ppm): delta 0.94-0.85 (t, 6H, -CH3), 1.50-1.24 (m, 12H, -(CH2)3-), 1.84-1.79(m, 4H, -CH2CH2O-), 4.07-4.02 (t, 4H, -CH2CH2O-), 4.37 (s, 4H, -OCH2-), 7.02-6.96 (t,8H, Ar-H), 7.33-7.24 (d, 8H, Ar-H), 7.97-7.94 (d, 4H, Ar-H), 8.16-8.13 (d, 4H, Ar-H), 8.49(s, 2H, -CH = N).

At the same time, in my other blogs, there are other synthetic methods of this type of compound, 4,4′-(Ethane-1,2-diylbis(oxy))dianiline, and friends who are interested can also refer to it.

Reference:
Article; Park, Joo Hoon; Singu, Bal Sydulu; Choi, Ok Byung; Lee, Hwan Myung; Lee, Jin Young; Kim, Sung Jo; Cha, Eun Hee; Park, Seon Nam; Kwak, Myeong Heon; So, Bong Keun; Kim, Ran Hee; Lee, Soo Min; Yoon, Kuk Ro; Molecular Crystals and Liquid Crystals; vol. 650; 1; (2017); p. 1 – 6;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Adding a certain compound to certain chemical reactions, such as: 6052-10-4, name is 4,4′-(Ethane-1,2-diylbis(oxy))dianiline, belongs to ethers-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 6052-10-4, Recommanded Product: 6052-10-4

The TGAE was synthesized (Fig. 1.) according to the reported procedure [23]. A 250-mL two-neck round bottom flask, equipped with magnetic stirrer, thermometer and condenser was charged with 4-(2-(4-aminophenoxy)ethoxy)benzenamine ethane (5.0 g, 0.02 mol), 40 mLtoluene and 1.5 mL 50% manganese nitrate aqueous solution. The reaction mixture was stirred at 333 K for 50 min, and epichlorohydrin (9.63 mL, 0.12 mol) was added slowly. The reaction mixture was kept at 353 K for1 h; then 50% aqueous tetramethylammonium chloride (TMAC, 0.25 g, 0.00, 228 mol) and 3.65 g (0.091 mol) sodium hydroxide were added slowly in portions within 10 min. After addition, the temperature was maintained at 348-353 K and 12 mL distilled water was added, stirred and heated to separate out organic layers, which was washed with brine, separated and concentrated to get TGAE as a viscous brown liquid. 4-(2-(4-(bis(oxiran-2-ylmethyl)amino)phenoxy)ethoxy)-N,Nbis(oxiran-2-ylmethyl) benzenamine TGAE Colour, dark brown viscous liquid, EEW 170.8 g eq-1, Yield, 80%. FTIR (upsilon cm-1): 905 (C-O-C epoxide, asym), 810 (C-O-C epoxide, sym), 1223, 1067 (C-O, alkyl phenyl alcohol), 1375 (C-N ter. amine), 1507, 1456 (C=C aromatic), 2918 (C-H aliphatic), 1H NMR (300 MHz, CDCl3-d3): delta(ppm) = 2.8 (4H, m, 1a), 2.6 (4H, m, 1b), 3.2 (4H, m, 2), 3.7 (4H, m, 3a), 3.4 (4H, m, 3b), 6.8 (4H, dd, J = 9.3, 3.0 Hz, 4), 6.9 (4H, dd, J = 9.3, 2.4 Hz, 5) and 4.25 (4H, s,8). 13C NMR (300 MHz, CDCl3-d3): delta(ppm) = 45.37 (1), 47.18 (2), 50.74 (3), 114.8 (4), 116.4 (5), 151.3 (6), 143.4(7) and 67.4 (8).

At the same time, in my other blogs, there are other synthetic methods of this type of compound, 4,4′-(Ethane-1,2-diylbis(oxy))dianiline, and friends who are interested can also refer to it.

Reference:
Article; Siddiqi, Humaira Masood; Siraj, Amna; Khalid, Naila; Akhtar, Zareen; Zia Ul Haq, Muhammad; Journal of Thermal Analysis and Calorimetry; vol. 132; 1; (2018); p. 205 – 214;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem