Category: 578-58-5

Gao, Hui; Chen, Xinyu; Wang, Pei-Long; Shi, Meng-Meng; Shang, Ling-Long; Guo, Heng-Yi; Li, Hongji; Li, Pinhua published an article in 2022, the title of the article was Electrochemical benzylic C-H arylation of xanthenes and thioxanthenes without a catalyst and oxidant.Reference of 2-Methylanisole And the article contains the following content:

A catalyst-free and oxidant-free C-H arylation of xanthenes and thioxanthenes I (R1 = H, Me, OH, Cl, etc.; R2 = H, OMe; R3R4 = -CH=CH-CH=CH-; X = O, S) using electrochem. has been developed, which affords a number of cross-coupling products II (R5 = 4-methoxyphenyl, 4-methoxy-3-methylphenyl, 4-methoxy-3,5-dimethylphenyl, 2H-1,3-benzodioxol-5-yl, etc.) in moderate to good yields. This method is atom- and step-economical as it uses cheap and easily available arenes and heteroarenes as partners directly and the C(sp2)-H/C(sp3)-H type cross-coupling reaction. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).Reference of 2-Methylanisole

The Article related to aryl xanthene preparation, xanthene arene electrochem arylation reaction, arylthioxanthene preparation, arene thioxanthene electrochem arylation reaction, Heterocyclic Compounds (One Hetero Atom): Benzopyrans (Including Coumarins, Isocoumarins, Chromones, Benzopyrones, Dibenzopyrans, and Other Arenopyrans) and other aspects.Reference of 2-Methylanisole

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On January 7, 2021, Richards, Kenza; Petit, Eddy; Legrand, Yves-Marie; Grison, Claude published an article.Application of 578-58-5 The title of the article was Eco-Friendly Methodology for the Formation of Aromatic Carbon-Heteroatom Bonds by Using Green Ionic Liquids. And the article contained the following:

A new sustainable method is reported for the formation of aromatic carbon-heteroatom bonds under solvent-free and mild conditions (no co-oxidant, no strong acid and no toxic reagents) by using a new type of green ionic liquid The bromination of methoxy arenes was chosen as a model reaction. The reaction methodol. is based on only using natural sodium bromine, which is transformed into an electrophilic brominating reagent within an ionic liquid, easily prepared from the melted salt FeCl3 hexahydrate. Bromination reactions with this in-situ-generated reagent gave good yields and excellent regioselectivity under simple and environmentally friendly conditions. To understand the unusual bromine polarity reversal of sodium bromine without any strong oxidant, the mol. structure of the reaction medium was characterized by Raman and direct infusion electrospray ionization mass spectroscopy (ESI-MS). An extensive computational investigation using d. functional theory methods was performed to describe a mechanism that suggests indirect oxidation of Br- through new iron adducts. The versatility of the methodol. was successively applied to nitration and thiocyanation of methoxy arenes using KNO3 and KSCN in melted hexahydrated FeCl3. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).Application of 578-58-5

The Article related to haloarene green preparation melted ferric chloride ionic liquid, dft-hf calculation, aromatic electrophilic substitution, ionic liquids, mixed melted salts, sustainable chemistry and other aspects.Application of 578-58-5

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On August 26, 2022, Zhang, Qingyu; Chan, Yung-Yin; Zhang, Muyin; Yeung, Ying-Yeung; Ke, Zhihai published an article.Name: 2-Methylanisole The title of the article was Hypervalent Chalcogenonium…蟺 Bonding Catalysis. And the article contained the following:

A proof-of-concept study of hypervalent chalcogenonium…蟺 bonding catalysis was performed. A new catalytic strategy using 1,2-oxaselenolium salts as chalcogen bond donors and alkenes as chalcogen bond acceptors is described. The feasibility of this concept is demonstrated by the use of trisubstituted selenonium salts in the metal-free catalytic hydrofunctionalization and polymerization of alkenes via unconventional seleniranium ion-like intermediates. The results indicate that counter anions have a significant effect on the catalysis based on hypervalent chalcogenonium…蟺 bonding interactions. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).Name: 2-Methylanisole

The Article related to hypervalent oxaselenolium bonding catalysis hydrofunctionalization styrene polymerization, chalcogen bonding, hydrofunctionalization, hypervalent selenium, lewis acids, organocatalysis and other aspects.Name: 2-Methylanisole

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Zhang, Dejin; Yang, Guoqiang; Xiong, Junping; Liu, Jia; Hu, Xingbang; Zhang, Zhibing published an article in 2021, the title of the article was An efficient method to prepare aryl acetates by the carbonylation of aryl methyl ethers or phenols.Safety of 2-Methylanisole And the article contains the following content:

A method of preparing aryl acetates ROC(O)CH3 (R = Ph, 2-(propan-2-yl)phenyl, 4-fluorophenyl, 2,3,5-trimethylphenyl, etc.) by the carbonylation of aryl Me ethers ROCH3 or phenols ROH under low CO pressure was developed. Good to excellent yields of aryl acetates were obtained using different substrates, and a possible reaction mechanism was proposed by conducting a series of control experiments This method may provide a potential way for the utilization of lignin. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).Safety of 2-Methylanisole

The Article related to aryl acetate preparation, arylmethyl ether carbonmonoxide methyl iodide carbonylation iridium chloride catalyst, phenol carbonmonoxide methyl iodide carbonylation iridium chloride catalyst and other aspects.Safety of 2-Methylanisole

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On August 1, 2022, Sukowski, Verena; van Borselen, Manuela; Mathew, Simon; Fernandez-Ibanez, M. Angeles published an article.Application In Synthesis of 2-Methylanisole The title of the article was S,O-Ligand Promoted meta-C-H Arylation of Anisole Derivatives via Palladium/Norbornene Catalysis. And the article contained the following:

Here, a new catalytic system based on palladium/norbornene and an S,O-ligand for the meta-C-H arylation of aryl ethers that significantly outperforms previously reported systems has been developed. The unique ability of this system to employ alkoxyarene substrates bearing electron donating and withdrawing substituents is demonstrated. Addnl., ortho-substituted aryl ethers are well tolerated, overcoming the “ortho constraint”, which is the necessity to have a meta-substituent on the alkoxyarene to achieve high reaction efficiency, by enlisting novel norbornene mediators. Remarkably, for the first time the monoarylation of alkoxyarenes is achieved efficiently enabling the subsequent introduction of a second, different aryl coupling partner to rapidly furnish unsym. terphenyls. Further insight into the reaction mechanism was achieved by isolation and characterization of some Pd-complexes-before and after meta C-H activation-prior to evaluation of their resp. catalytic activities. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).Application In Synthesis of 2-Methylanisole

The Article related to biphenyl terphenyl alkoxy preparation, aryl ether regioselective arylation aryl halide palladium norbornene catalyst, arylation, c鈭抙 activation, ligand design, palladium, reaction mechanisms and other aspects.Application In Synthesis of 2-Methylanisole

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On February 19, 2020, Kawasaki, Tairin; Ishida, Naoki; Murakami, Masahiro published an article.Reference of 2-Methylanisole The title of the article was Dehydrogenative Coupling of Benzylic and Aldehydic C-H Bonds. And the article contained the following:

A photoinduced dehydrogenative coupling reaction between benzylic and aldehydic C-H bonds was reported. When a solution of an alkylbenzene and an aldehyde in Et acetate was irradiated with visible light in the presence of iridium and nickel catalysts, a coupled 伪-aryl ketone was formed with evolution of dihydrogen. An analogous C-C bond forming reaction occurs between a C-H bond next to the nitrogen of an N-methylamide and an aldehydic C-H bond to produce an 伪-amino ketone. These reactions provide a straightforward pathway from readily available materials leading to valued structural motifs of pharmacol. relevance. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).Reference of 2-Methylanisole

The Article related to alkylarene aldehyde iridium nickel catalyst dehydrogenative cross coupling, aryl ketone preparation, methylamide aldehyde iridium nickel catalyst dehydrogenative cross coupling, amino ketone preparation and other aspects.Reference of 2-Methylanisole

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On February 1, 2021, Murugesan, Kathiravan; Donabauer, Karsten; Koenig, Burkhard published an article.Related Products of 578-58-5 The title of the article was Visible-Light-Promoted Metal-Free Synthesis of (Hetero)Aromatic Nitriles from C(sp3)-H Bonds. And the article contained the following:

The metal-free activation of C(sp3)-H bonds to value-added products is of paramount importance in organic synthesis. We report the use of the com. available organic dye 2,4,6-triphenylpyrylium tetrafluoroborate (TPP) for the conversion of methylarenes to the corresponding aryl nitriles via a photocatalytic process. Applying this methodol., a variety of cyanobenzenes have been synthesized in good to excellent yield under metal- and cyanide-free conditions. We demonstrate the scope of the method with over 50 examples including late-stage functionalization of drug mols. (celecoxib) and complex structures such as L-menthol, amino acids, and cholesterol derivatives Furthermore, the presented synthetic protocol is applicable for gram-scale reactions. In addition to methylarenes, selected examples for the cyanation of aldehydes, alcs. and oximes are demonstrated as well. Detailed mechanistic investigations have been carried out using time-resolved luminescence quenching studies, control experiments, and NMR spectroscopy as well as kinetic studies, all supporting the proposed catalytic cycle. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).Related Products of 578-58-5

The Article related to photocatalytic cyanation methylarene aldehyde alc oxime, visible light promoted synthesis heteroaromatic aromatic nitrile, c鈭抙 functionalization, ammoxidation, methylarenes, nitriles, photoredox catalysis and other aspects.Related Products of 578-58-5

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Pan, Aaron; Chojnacka, Maja; Crowley, Robert III; Gottemann, Lucas; Haines, Brandon E.; Kou, Kevin G. M. published an article in 2022, the title of the article was Synergistic Bronsted/Lewis acid catalyzed aromatic alkylation with unactivated tertiary alcohols or di-tert-butylperoxide to synthesize quaternary carbon centers.COA of Formula: C8H10O And the article contains the following content:

Dual Bronsted/Lewis acid catalysis involving environmentally benign, readily accessible protic acid and iron promotes site-selective tert-butylation of electron-rich arenes using di-tert-butylperoxide. This transformation inspired the development of a synergistic Bronsted/Lewis acid catalyzed aromatic alkylation that fills a gap in the Friedel-Crafts reaction literature by employing unactivated tertiary alcs. as alkylating agents, leading to new quaternary carbon centers. Corroborated by DFT calculations, the Lewis acid serves a role in enhancing the acidity of the Bronsted acid. The use of non-allylic, non-benzylic, and non-propargylic tertiary alcs. represents an underexplored area in Friedel-Crafts reactivity. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).COA of Formula: C8H10O

The Article related to aromatic hydrocarbon ditert butylperoxide acid catalyst regioselective alkylation green, tertiary alc aromatic hydrocarbon acid catalyst regioselective alkylation green, quaternary alkylarene preparation and other aspects.COA of Formula: C8H10O

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Jiang, Heyan; Zang, Cuicui; Cheng, Hongmei; Sun, Bin; Gao, Xue published an article in 2021, the title of the article was Photocatalytic green synthesis of benzazoles from alcohol oxidation/toluene sp3 C-H activation over metal-free BCN: effect of crystallinity and N-B pair exposure.Recommanded Product: 578-58-5 And the article contains the following content:

Porous borocarbonitride (P-BCN), with the characteristics of enhanced crystallinity and improved N-B pair exposure, was prepared with a simple KCl-assisted molten salt strategy. Efficient heterogeneous photocatalytic tandem synthesis of benzazoles I [R = n-Pr, Ph, 4-MeC6H4, etc.; X = N, O, S] from alc. oxidation/toluene sp3 C-H activation was achieved firstly over the metal-free P-BCN using visible light and the green oxidant O2, with only water as a byproduct. Various o-thio/hydroxy/aminoanilines and alcs. or toluenes could be converted to the corresponding 2-substituted benzothiazoles I [R = n-Pr, Ph, 4-MeC6H4, etc.; X = S], benzoxazoles I [R = n-Pr, Ph, 4-MeC6H4, etc.; X = O] and benzimidazoles I [R = n-Pr, Ph, 4-MeC6H4, etc.; X = N] with good to excellent photocatalytic performance. The improved photocatalytic performance in comparison to bulk BCN should be due to the crystallinity-enhancement-induced improvement in charge separation and transmission. The increased N-B pair exposure promoted superoxide radical generation due to the electron-enriched N atoms, as well as improved oxidation ability due to the valence band constructed by the B 2p orbital. This work presented a green and efficient synthetic strategy toward benzazoles I and other fine chems. via metal-free heterogeneous photocatalysis. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).Recommanded Product: 578-58-5

The Article related to borocarbonitride preparation, benzazole aryl green preparation photocatalysis, alc aniline oxidation catalyst borocarbonitride, methyl aryl aniline carbon hydrogen activation catalyst borocarbonitride and other aspects.Recommanded Product: 578-58-5

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Mondal, Haripriyo; Sk, Raja Md; Maji, Modhu Sudan published an article in 2020, the title of the article was Cooperativity within the catalyst: alkoxyamide as a catalyst for bromocyclization and bromination of (hetero)aromatics.Application In Synthesis of 2-Methylanisole And the article contains the following content:

N-Methoxy-1-butanesulfonamide was a recyclable catalyst for the activation of N-bromosuccinimide to perform bromocyclization and bromination reactions of unsaturated carboxylic acids, alkenes and indoles with pendant nucleophiles, and arenes in heptane, where adequate suppression of the background reactions was observed, to yield bromolactones, bromomethyl-substituted heterocycles, fused indolines such as pyrroloindolines, and aryl bromides. The key feature of the active site is the alkoxy group attached to the sulfonamide moiety, which facilitates the acceptance as well as the delivery of bromonium species from the bromine source to the substrates. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).Application In Synthesis of 2-Methylanisole

The Article related to bromolactone aryl bromide chemoselective preparation, methoxybutanesulfonamide catalyst bromosuccinimide mediated bromocyclization bromination, chemoselective bromination bromocyclization methoxysulfonamide catalyst bromosuccinimide and other aspects.Application In Synthesis of 2-Methylanisole

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem