Category: 562085-85-2

Synthesis of N-azaaryl anilines: an efficient protocol via smiles rearrangement was written by Xia, Shuai;Wang, Li-Ying;Sun, Heng-Zhi;Yue, Huan;Wang, Xiu-Hua;Tan, Jia-Lian;Wang, Yin;Hou, Di;He, Xiao-Yan;Mun, Ki-Cheol;Kumar, B. Prem;Zuo, Hua;Shin, Dong-Soo. And the article was included in Bulletin of the Korean Chemical Society in 2013.Safety of N-(4-Methoxyphenyl)pyridin-3-amine The following contents are mentioned in the article:

An efficient process for the synthesis of N-azaaryl anilines involves a Smiles rearrangement as a tool. A variety of N-azaaryl anilines were generated by a reaction of substituted phenols, substituted anilines, aminopyridine derivatives, chloroacetyl chloride or pyridinol derivatives, under basic reaction conditions in good to excellent yields. The synthesis of the target compounds was achieved by a reaction of 3-pyridinamine with chloroacetyl chloride, formation of an amide and reaction with phenol, thus providing 2-(phenoxy)-N-(3-pyridinyl)acetamide (I) and similar intermediates, which underwent a Smiles rearrangement. The title compounds thus formed included N-phenyl-3-pyridinamine (II) and related substances, such as N-phenyl-2-pyridinamine derivatives This study involved multiple reactions and reactants, such as N-(4-Methoxyphenyl)pyridin-3-amine (cas: 562085-85-2Safety of N-(4-Methoxyphenyl)pyridin-3-amine).

N-(4-Methoxyphenyl)pyridin-3-amine (cas: 562085-85-2) belongs to ethers. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Safety of N-(4-Methoxyphenyl)pyridin-3-amine

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δ-Carbolines and their ring-opened analogs: Synthesis and evaluation against fungal and bacterial opportunistic pathogens was written by Mazu, Tryphon K.;Etukala, Jagan R.;Jacob, Melissa R.;Khan, Shabana I.;Walker, Larry A.;Ablordeppey, Seth Y.. And the article was included in European Journal of Medicinal Chemistry in 2011.Quality Control of N-(4-Methoxyphenyl)pyridin-3-amine The following contents are mentioned in the article:

Previous studies have indicated that the δ-carboline ring system derived from the natural product cryptolepine may represent a pharmacophore for anti-infective activity. The design and synthesis of a small library of substituted δ-carbolines and the evaluation of their antifungal and antibacterial activities is reported. An evaluation of the antibacterial activity of a previously reported library of ring-opened analogs was also conducted to provide an opportunity to test the hypothesis that both group of compounds may have the same biol. target. Results indicate that against a selected group of fungal pathogens, substituted δ-carbolinium analogs displayed higher potency and several fold lower cytotoxicity than cryptolepine the parent natural product. Both the δ-carbolinium compounds and their ring-opened analogs, exhibited equally high antibacterial activity against the selected pathogens and especially against the gram pos. bacteria evaluated. This study involved multiple reactions and reactants, such as N-(4-Methoxyphenyl)pyridin-3-amine (cas: 562085-85-2Quality Control of N-(4-Methoxyphenyl)pyridin-3-amine).

N-(4-Methoxyphenyl)pyridin-3-amine (cas: 562085-85-2) belongs to ethers. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Quality Control of N-(4-Methoxyphenyl)pyridin-3-amine

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Nickel Dual Photoredox Catalysis for the Synthesis of Aryl Amines was written by Key, Ryan J.;Vannucci, Aaron K.. And the article was included in Organometallics in 2018.Electric Literature of C12H12N2O The following contents are mentioned in the article:

In this work, a new dual photoredox nickel catalysis system has been utilized for the synthesize of aryl amines. Previously, our group has shown that a nickel catalyst in conjunction with a photosensitizer and a sacrificial electron donor can cross-couple C-C bonds via photoredox-assisted reductive coupling. Here we have built upon that system to develop a redox-neutral cross-coupling system for the formation of C-N bonds. The catalytic system is composed of just a nickel cross-coupling catalyst, a Ru photocatalyst, and base and is capable of coupling amines with aryl halides in good to excellent yields. Furthermore, it was found that these reactions are functional under ambient conditions with catalyst loadings of 1 mol %. Spectroscopic studies provide support that this amination mechanism proceeds via a nitrogen-based radical intermediate. This N-radical mechanism offers direct synthetic access to di- and triaryl amines from nickel photocatalysis. This study involved multiple reactions and reactants, such as N-(4-Methoxyphenyl)pyridin-3-amine (cas: 562085-85-2Electric Literature of C12H12N2O).

N-(4-Methoxyphenyl)pyridin-3-amine (cas: 562085-85-2) belongs to ethers. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Electric Literature of C12H12N2O

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Highly reactive, general and long-lived catalysts for palladium-catalyzed amination of heteroaryl and aryl chlorides, bromides, and iodides: Scope and structure-activity relationships. [Erratum to document cited in CA148:585292] was written by Shen, Qilong;Ogata, Tokutaro;Hartwig, John F.. And the article was included in Journal of the American Chemical Society in 2008.Product Details of 562085-85-2 The following contents are mentioned in the article:

On page 6590, the halogens in the first and second products were incorrectly shown as Br and I, resp. The correct version of the equation is given. This study involved multiple reactions and reactants, such as N-(4-Methoxyphenyl)pyridin-3-amine (cas: 562085-85-2Product Details of 562085-85-2).

N-(4-Methoxyphenyl)pyridin-3-amine (cas: 562085-85-2) belongs to ethers. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Product Details of 562085-85-2

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[(CyPF-^tBu)PdCl₂]: An Air-Stable, One-Component, Highly Efficient Catalyst for Amination of Heteroaryl and Aryl Halides was written by Shen, Qilong;Hartwig, John F.. And the article was included in Organic Letters in 2008.Formula: C12H12N2O The following contents are mentioned in the article:

An air- and moisture-stable palladium catalyst, [(CyPF-^tBu)PdCl₂] (1), for coupling of heteroaryl chlorides, bromides, and iodides with a variety of primary amines is described. Most of these reactions occurred in high yield with 0.001-0.05 mol % catalyst loading. The reactions tolerated a wide range of functional groups. This study involved multiple reactions and reactants, such as N-(4-Methoxyphenyl)pyridin-3-amine (cas: 562085-85-2Formula: C12H12N2O).

N-(4-Methoxyphenyl)pyridin-3-amine (cas: 562085-85-2) belongs to ethers. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Formula: C12H12N2O

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Carbene adduct of cyclopalladated ferrocenylimine-assisted synthesis of aminopyridine derivatives by the amination of chloropyridines with primary and secondary amines was written by Mu, Bing;Li, Jingya;Wu, Yangjie. And the article was included in Applied Organometallic Chemistry in 2013.HPLC of Formula: 562085-85-2 The following contents are mentioned in the article:

An efficient, simple way to synthesize aminopyridine derivatives is presented, based on Buchwald-Hartwig aminations. Using 1 mol% N-heterocyclic carbene adduct of cyclopalladated ferrocenylimine in the presence of 1.5 equivalent tBuOK as base in dioxane at 110°C offered moderate to excellent yields in the reaction of chloropyridines with primary and secondary amines, including sterically hindered amines and alkyl amines. This study involved multiple reactions and reactants, such as N-(4-Methoxyphenyl)pyridin-3-amine (cas: 562085-85-2HPLC of Formula: 562085-85-2).

N-(4-Methoxyphenyl)pyridin-3-amine (cas: 562085-85-2) belongs to ethers. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.HPLC of Formula: 562085-85-2

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Ether – Wikipedia,
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Novel Pd-N-heterocyclic carbene complexes: design, synthesis and application in Buchwald-Hartwig cross coupling reaction was written by Wang, Fan;Hu, Yucai;Shen, An;Cao, Yucai. And the article was included in Youji Huaxue in 2017.Reference of 562085-85-2 The following contents are mentioned in the article:

N-Heterocyclic carbene (NHC) palladium complexes with different imine ligands had been developed and applied in Buchwald-Hartwig cross coupling reaction. The structure of imine ligand would influence the catalytic activity apparently. Especially, the imine ligand with electron withdrawing group performed best. Low to 0.5 mol% catalyst loading could realize effective Buchwald-Hartwig cross coupling reaction between various aryl chlorides and amines. This study involved multiple reactions and reactants, such as N-(4-Methoxyphenyl)pyridin-3-amine (cas: 562085-85-2Reference of 562085-85-2).

N-(4-Methoxyphenyl)pyridin-3-amine (cas: 562085-85-2) belongs to ethers. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Reference of 562085-85-2

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Long alkyl chain NHC palladium complexes for the amination and hydrodehalogenation of aryl chlorides in lipophilic media was written by Ruehling, Andreas;Rakers, Lena;Glorius, Frank. And the article was included in ChemCatChem in 2017.HPLC of Formula: 562085-85-2 The following contents are mentioned in the article:

Herein, the authors present the synthesis of long chain NHC palladium complexes, which are soluble in lipophilic solvents, such as n-heptane. These complexes enable the amination and hydrodehalogenation of aryl chlorides in moderate to good yields for a broad range of substrates in n-heptane. Taking into account the caloric power of alkane solvents, such transformations could become a welcome alternative to established solvents (e.g. dioxane) from an industrial point of view. This study involved multiple reactions and reactants, such as N-(4-Methoxyphenyl)pyridin-3-amine (cas: 562085-85-2HPLC of Formula: 562085-85-2).

N-(4-Methoxyphenyl)pyridin-3-amine (cas: 562085-85-2) belongs to ethers. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.HPLC of Formula: 562085-85-2

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Visible-Light- and PPh₃-Mediated Direct C-N Coupling of Nitroarenes and Boronic Acids at Ambient Temperature was written by Manna, Kartic;Ganguly, Tanusree;Baitalik, Sujoy;Jana, Ranjan. And the article was included in Organic Letters in 2021.HPLC of Formula: 562085-85-2 The following contents are mentioned in the article:

Herein a metal-free, visible-light- and triphenylphosphine-mediated intermol., reductive amination between nitroarenes and boronic acids at ambient temperature without any photocatalyst is presented. Mechanistically, a slow reduction of nitroarenes to a nitroso and, finally, a nitrene intermediate occurs that leads to the amination product with concomitant 1,2-aryl/-alkyl migration from a boronate complex. A wide range of nitroarenes underwent C-N coupling with aryl-/alkylboronic acids providing high yields. This study involved multiple reactions and reactants, such as N-(4-Methoxyphenyl)pyridin-3-amine (cas: 562085-85-2HPLC of Formula: 562085-85-2).

N-(4-Methoxyphenyl)pyridin-3-amine (cas: 562085-85-2) belongs to ethers. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.HPLC of Formula: 562085-85-2

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Hypervalent Iodine(III) in Direct Oxidative Amination of Arenes with Heteroaromatic Amines was written by Manna, Srimanta;Serebrennikova, Polina O.;Utepova, Irina A.;Antonchick, Andrey P.;Chupakhin, Oleg N.. And the article was included in Organic Letters in 2015.Reference of 562085-85-2 The following contents are mentioned in the article:

A novel, mild, and practical method of amination of simple nonfunctionalized arenes under metal free conditions has been developed. The approach allows coupling of electron-rich arenes with amino derivatives of electron-deficient heterocycles providing rapid access to scaffolds of bioactive compounds and is based on the application of the hypervalent iodine(III) reagent as an oxidant. Regioselective functionalization of C-H bonds of arenes by the formation of C-N bonds under organocatalytic conditions was demonstrated. This study involved multiple reactions and reactants, such as N-(4-Methoxyphenyl)pyridin-3-amine (cas: 562085-85-2Reference of 562085-85-2).

N-(4-Methoxyphenyl)pyridin-3-amine (cas: 562085-85-2) belongs to ethers. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Reference of 562085-85-2

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem