529-28-2 Archives - Ethers-buliding-blocks

Zhou, Guoquan’s team published research in Synlett in 2019 | CAS: 529-28-2

1-Iodo-2-methoxybenzene(cas: 529-28-2) participates in palladium catalyzed enantioselective Heck arylation of 2,3-dihydrofuran in the presence of chiral ionic liquids containing L-prolinate and L-lactate anions and non-chiral quaternary ammonium cations.Electric Literature of C7H7IO

The author of 《A Newly Designed Carbohydrate-Derived Alkylamine Promotes Ullmann Type C-N Coupling Catalyzed by Copper in Water》 were Zhou, Guoquan; Chen, Wen; Zhang, Shihui; Liu, Xuemin; Yang, Zehui; Ge, Xin; Fan, Hua-Jun. And the article was published in Synlett in 2019. Electric Literature of C7H7IO The author mentioned the following in the article:

In the presence of the diglucosylethanediamine I and CuI, aryl iodides underwent green Ullman-type coupling reactions with heterocyclic amines and aniline in water mediated by Cs2CO3 to yield N-arylated nitrogen heterocycles (particularly N-aryl imidazoles and indoles) and N-phenyl-p-anisidine. The solubility of 4-iodoanisole in water in the presence and absence of I was measured; I likely functions by both chelating copper and by promoting the dissolution of 4-iodoanisole in water. In addition to this study using 1-Iodo-2-methoxybenzene, there are many other studies that have used 1-Iodo-2-methoxybenzene(cas: 529-28-2Electric Literature of C7H7IO) was used in this study.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Nan, Liu’s team published research in RSC Advances in 2020 | CAS: 529-28-2

1-Iodo-2-methoxybenzene(cas: 529-28-2) is a useful synthetic intermediate. It can be used in the synthesis of piperidinyl diaminopyrimidines as cyclin-dependent kinase inhibitors with antitumor activity and polysubstituted benzofuran derivatives as novel inhibitors of parasitic growth.Safety of 1-Iodo-2-methoxybenzene

《Carbonylative Suzuki-Miyaura cross-coupling by immobilized Ni@Pd NPs supported on carbon nanotubes》 was published in RSC Advances in 2020. These research results belong to Nan, Liu; Cai, Yalan; Li, Jixiang; Ouyang, Dujuan; Duan, Wenhui; Rouhi, Jalal; Mustapha, Mazli. Safety of 1-Iodo-2-methoxybenzene The article mentions the following:

In this study, a novel carbon nanotube (CNT) based nanocatalyst (Ni@Pd/CNT) was synthesized by modifying CNTs using Ni@Pd core-shell nanoparticles (NPs). Ni@Pd/CNT was used in catalytic carbonylative cross-coupling between aryl iodides and phenylboronic acid to afford diaryl ketones ArC(O)Ph [Ar = Ph, 2-MeC6H4, 2-NH2C6H4, etc.]. The Ni@Pd NPs possessed a magnetic nickel (Ni) core with a palladium (Pd) structural composite shell. Thus, the use of Ni had led to a reduced consumption of Pd without sacrificing the overall catalytic performance, simultaneously making it reusable as it could be conveniently recovered from the reaction mixture by using an external magnetic field. Immobilization of the Ni@Pd NPs on carbon nanotubes not only prevented their aggregation, but also significantly enhanced the accessibility of the catalytically active sites. The above mentioned approach based on carbon nanotubes and Ni@Pd NPs provided a useful platform for the fabrication of noble-metal-based nanocatalysts with easy accessibility and low cost, which may allow for an efficient green alternative for various catalytic reductions In addition to this study using 1-Iodo-2-methoxybenzene, there are many other studies that have used 1-Iodo-2-methoxybenzene(cas: 529-28-2Safety of 1-Iodo-2-methoxybenzene) was used in this study.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Wang, Ying-yu’s team published research in Synlett in 2020 | CAS: 529-28-2

《Copper-Catalyzed Methylthiolation of Aryl Iodides and Bromides with Dimethyl Disulfide in Water》 was published in Synlett in 2020. These research results belong to Wang, Ying-yu; Wu, Xiang-mei; Yang, Ming-hua. Recommanded Product: 1-Iodo-2-methoxybenzene The article mentions the following:

An efficient route to aryl Me sulfides through the copper-catalyzed coupling reaction of aryl iodides or bromides with di-Me disulfide in water was described. Electron-donating and electron-withdrawing functional groups in the substrates were tolerated, and the corresponding products were obtained in moderate to good yields. In the experimental materials used by the author, we found 1-Iodo-2-methoxybenzene(cas: 529-28-2Recommanded Product: 1-Iodo-2-methoxybenzene)

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Qi, Xinxin’s team published research in ChemCatChem in 2019 | CAS: 529-28-2

In 2019,ChemCatChem included an article by Qi, Xinxin; Lai, Ming; Zhu, Min-Jie; Peng, Jin-Bao; Ying, Jun; Wu, Xiao-Feng. Safety of 1-Iodo-2-methoxybenzene. The article was titled 《1-Arylvinyl formates: A New CO Source and Ketone Source in Carbonylative Synthesis of Chalcone Derivatives》. The information in the text is summarized as follows:

1-Arylvinyl formates as a kind of new CO surrogate was explored for the first time. Most of the known CO precursors usually produced undesired residuals, which were to be removed. In this strategy, after CO release, the in-situ generated acetophenones from 1-arylvinyl formates were successfully applied as a good ketone source in the synthesis of chalcones with benzaldehydes via a palladium-catalyzed reductive carbonylation reaction. A variety of chalcones were isolated in satisfactory to good yields with good substrates compatibilities under mild conditions.1-Iodo-2-methoxybenzene(cas: 529-28-2Safety of 1-Iodo-2-methoxybenzene) was used in this study.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Mao, Pu’s team published research in ChemistrySelect in 2020 | CAS: 529-28-2

《Nickel-Catalyzed Carbon-Sulfur Bond Formation through Couplings of Aryl Iodides and Aryl Ethanethioates》 was published in ChemistrySelect in 2020. These research results belong to Mao, Pu; Sui, Hong-Da; Yuan, Jin-Wei; Xiao, Yong-Mei; Yang, Liang-Ru; Mai, Wen-Peng. Electric Literature of C7H7IO The article mentions the following:

A nickel-catalyzed reductive coupling between aryl iodides 2-R-3-R1-4-R2-C6H2I (R = H, OMe, Cl; R1 = H, Me; R2 = H, F, CF3, Ph, etc.) and aryl ethanethioates 3-R3-4-R4-C6H3XC(O)R5 (X = S, O; R3 = H, F; R4 = H, Me, Cl, OMe, OCF3; R5 = Me, Ph, 2,2,2-trifluoroethyl, 3,3,3-trifluoropropyl) has been developed to afford diaryl sulfides 2-R-3-R1-4-R2-C6H2SC6H3-3-R3-4-R4. This method provides a novel and practical route to aryl thioetherification and can be effectively applied to electronically diverse aryl iodides without expensive metals such as palladium and ruthenium. In the experiment, the researchers used 1-Iodo-2-methoxybenzene(cas: 529-28-2Electric Literature of C7H7IO)

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Liu, Ze-Shui’s team published research in Tetrahedron in 2019 | CAS: 529-28-2

Category: ethers-buliding-blocksIn 2019 ,《5-Norbornene-2-carboxylic acid: Another catalytic mediator for Catellani-type reactions》 was published in Tetrahedron. The article was written by Liu, Ze-Shui; Qian, Guangyin; Gao, Qianwen; Wang, Peng; Cheng, Hong-Gang; Hua, Yu; Zhou, Qianghui. The article contains the following contents:

The discovery of inexpensive 5-norbornene-2-carboxylic acid (N4) as a general catalytic mediator (20 mol%) to facilitate ortho C-H activation and the following C-C bond formation of aryl iodides. Firstly, a co-operative catalytic system comprising N4 and palladium/XPhos complex was developed for the novel Catellani/redox-relay Heck cascade to construct tetrahydronaphthalenes e.g., I and indanes e.g., II that contain a quaternary carbon stereogenic center. The striking feature of this work was the avoidance of stoichiometric NBE mediator that were usually required for Catellani-type reactions. Preliminary results demonstrated that N4 could acted as a general catalytic mediator to replace NBE for other Catellani-type reactions, which would undoubtedly inspire future developments in the field of cooperative catalysis. Finally, control experiments indicated that the carboxylic acid moiety of N4 played an essential role in its ability to serve as a superior mediator. The experimental process involved the reaction of 1-Iodo-2-methoxybenzene(cas: 529-28-2Category: ethers-buliding-blocks)

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Li, Yafei’s team published research in Organometallics in 2021 | CAS: 529-28-2

Li, Yafei; Dang, Yan; Li, Dawei; Pan, Huifen; Zhang, Liang; Wang, Li; Cao, Zhu; Li, Yahong published their research in Organometallics in 2021. The article was titled 《Zinc Complexes with an Ethylene-Bridged Bis(β-diketiminate) Ligand: Syntheses, Structures, and Applications as Catalysts in the Borylation of Aryl Iodides》.Synthetic Route of C7H7IO The article contains the following contents:

A dinucleating bis(β-diketiminate) ligand with a flexible bridge has been employed to synthesize zinc complexes. The ligand, abbreviated H2L (H2L = N-(4-((2-((4-((2,6-diisopropylphenyl)imino)pent-2-en-2-yl)amino)ethyl)imino)pent-2-en-2-yl)-2,6-diisopropylaniline), was deprotonated with ZnEt2 to afford [LZn2Et2] (1). Reactions of 1 with 2 equiv of BnOH and nBuOH, resp., gave access to [LZn2(OBn)2]·C6H14 (2·C6H14) and [LZn2(OnBu)2] (3). Treatment of 1 with 2 equiv of I2 in THF produced [LZn2I2(THF)2]·2THF (4·2THF). X-ray single-crystal diffraction analyses revealed that they are all heteroleptic bimetallic compounds with two metal centers being chelated by one ligand set. The structurally similar compounds 1 and 4·2THF possess approx. C2 symmetry, with two β-diketiminate units being arrayed in head-to-tail antiparallel mode. Thus, the mol. structures of 1 and 4·2THF exhibit a seesaw-like topol. The structures of 2·C6H14 and 3 are almost identical, in which two zinc atoms are shared by two ZnN2C3 six-membered rings, two Zn2ON2C2 seven-membered rings, and one Zn2O2 four-membered ring. Therefore, the metal cores of 2·C6H14 and 3 display a crownlike topol. All complexes are catalytically active for the borylation of aryl iodides with B2Pin2 (B2Pin2 = 4,4,4′,4′,5,5,5′,5′-octamethyl-2,2′-bis(1,3,2-dioxaborolane)). Complex 1 shows higher activity in comparison to 2, 3, and 4·2THF. The borylation reactions catalyzed by 1 could proceed under mild conditions and can be applied to a series of substrates with high functional group generality. This methodol. thus represents a novel use of β-diketiminate zinc complexes for C-I borylation. In addition to this study using 1-Iodo-2-methoxybenzene, there are many other studies that have used 1-Iodo-2-methoxybenzene(cas: 529-28-2Synthetic Route of C7H7IO) was used in this study.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Wu, Zhuo’s team published research in Chemical Science in 2021 | CAS: 529-28-2

Wu, Zhuo; Jiang, Hang; Zhang, Yanghui published an article in 2021. The article was titled 《Pd-catalyzed cross-electrophile Coupling/C-H alkylation reaction enabled by a mediator generated via C(sp3)-H activation》, and you may find the article in Chemical Science.Application of 529-28-2 The information in the text is summarized as follows:

Pd-catalyzed cascade cross-electrophile coupling and C-H alkylation reaction of 2-iodo-alkoxylarenes with alkyl chlorides were reported. Methoxy and benzyloxy groups, which were ubiquitous functional groups and common protecting groups, were utilized as crucial mediators via primary or secondary C(sp3)-H activation. The reaction provided an innovative and convenient access for the synthesis of alkylated phenol derivatives, which were widely found in bioactive compounds and organic functional materials.1-Iodo-2-methoxybenzene(cas: 529-28-2Application of 529-28-2) was used in this study.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Lin, Qifu’s team published research in Organic Letters in 2019 | CAS: 529-28-2

The author of 《Copper-Catalyzed Diastereoselective 1,2-Difunctionalization of Oxabenzonorbornadienes Leading to β-Thiocyanato Thioethers》 were Lin, Qifu; Yang, Wen; Yao, Yongqi; Chen, Shuqi; Tan, Yun; Chen, Donghan; Yang, Dingqiao. And the article was published in Organic Letters in 2019. Recommanded Product: 1-Iodo-2-methoxybenzene The author mentioned the following in the article:

A novel copper-catalyzed complete diastereoselective 1,2-difunctionalization of oxabicyclic alkenes has been developed. Two C-S bonds were constructed simultaneously on the oxabenzonorbornadienes leading to β-thiocyanato thioethers through the three-component (oxabicyclic alkenes, aryl iodides, and potassium thiocyanate), one-pot reaction. Various functional groups attached to the substrates were tolerated in this protocol to afford the corresponding β-thiocyanato thioether products in moderate yields. The experimental part of the paper was very detailed, including the reaction process of 1-Iodo-2-methoxybenzene(cas: 529-28-2Recommanded Product: 1-Iodo-2-methoxybenzene)

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Gergely, Mate’s team published research in Tetrahedron in 2019 | CAS: 529-28-2

In 2019,Tetrahedron included an article by Gergely, Mate; Kollar, Laszlo. Category: ethers-buliding-blocks. The article was titled 《Synthesis of benzamide-benzothiazole conjugates via palladium-catalyzed aminocarbonylation (hydrazinocarbonylation)》. The information in the text is summarized as follows:

The palladium-catalyzed aminocarbonylation of iodoarenes was investigated using 2-amino- and 2-hydrazinobenzothiazole as N-nucleophile. The reaction proved to be highly chemoselective in all cases: carboxamides and the corresponding carbohydrazides obtained by the acylation at the nitrogen adjacent to the C-2 of the benzothiazole moiety, were obtained exclusively and isolated in moderate to high yields. Systematic investigation of the reaction conditions revealed that the reaction requires relatively high temperature (higher than 70°). The effect of the carbon monoxide pressure is different in the synthesis of the two types of products: while the carboxamide formation is favored, the carbohydrazide formation is lowered by the increasing CO pressure. In the experimental materials used by the author, we found 1-Iodo-2-methoxybenzene(cas: 529-28-2Category: ethers-buliding-blocks)

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem