Category: 3929-47-3

Effects of Greek juniper (Juniperus excelsa) extract on immune responses and disease resistance against Yersinia ruckeri in rainbow trout (Oncorhynchus mykiss) was written by Bilen, Soner;Ispir, Selcuk;Kenanoglu, Osman Nezih;Tastan, Yigit;Gueney, Kerim;Terzi, Ertugrul. And the article was included in Journal of Fish Diseases in 2021.Category: ethers-buliding-blocks This article mentions the following:

This study investigated the effects of Greek juniper extract on immune responses of rainbow trout. In this experiment, 4 doses [0 (Control), 1 (J1), 4 (J4) and 8 (J8) mg/kg] of the extract were administered orally using an oral gavage twice a day for 14 days. Immune responses were measured on 7th and 14th days. On 14th day, Yersinia ruckeri was injected i.p. to all fish of all groups. On 14th day, ORP in fish of J1 group increased significantly. Lysozyme activity (LA) was increased in J8 group on 7th day (p < .05). On 14th day, a significant decrease was determined in J1 and J4 treatments in LA. Myeloperoxidase activity was significantly decreased in all groups irresp. of sampling times (p < .05). Interleukin (IL)-1β was significantly elevated in fish of J8 group on 7th day. IL-8 increased in fish of J8 and J4 groups on 7th day of the study. IL-12 gene expression was significantly up-regulated in J8 fish group on 7th day, and in J4 fish group on 14th day. Survival rate was higher in J8 treatment compared to the control and other treatments (p < .05). The results suggest that Juniperus excelsa provides protection against Y. ruckeri in rainbow trout. In the experiment, the researchers used many compounds, for example, 3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3Category: ethers-buliding-blocks).

3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides.Category: ethers-buliding-blocks

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Muscarinic agonist, (±)-quinuclidin-3-yl-(4-fluorophenethyl)(phenyl)carbamate: High affinity, but low subtype selectivity for human M₁ – M₅ muscarinic acetylcholine receptors was written by Lee, Na-Ra;Gujarathi, Satheesh;Bommagani, Shobanbabu;Siripurapu, Kiranbabu;Zheng, Guangrong;Dwoskin, Linda P.. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2019.Category: ethers-buliding-blocks This article mentions the following:

Quinuclidinyl N-phenylcarbamates and azabicyclic (arylethyl)phenylcarbamates such as I [R = 4-FC₆H₄, 4-MeOC₆H₄, 3,4-(MeO)₂C₆H₃] were prepared as ligands for the human M₅ muscarinic acetylcholine receptor (mAChR) for potential use in the treatment of drug abuse and chronic obstructive pulmonary disease; their binding to M₁-M₅ mAChR were determined I (R = 4-FC₆H₄) exhibited the highest affinities for M₁-M₅ mAChR (K_i = 2.0, 13, 2.6, 2.2, 1.8 nM for M₁, M₂, M₃, M₄, M₅ mAChR, resp.) of the tested ligands but was not selective for a single mAChR subtype. I (R = 4-FC₆H₄) acted as an agonist at mAChRs; the effect of I (R = 4-FC₆H₄) was inhibited by the nonselective mAChR antagonist scopolamine, and I (R = 4-FC₆H₄) augmented the release of dopamine evoked by oxotremorine. I (R = 4-MeOC₆H₄) was 17-fold selective for M₃ mAChR over M₂ mAChR. In the experiment, the researchers used many compounds, for example, 3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3Category: ethers-buliding-blocks).

3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive. The unique properties of ethers (i.e., that they are strongly polar, with nonbonding electron pairs but no hydroxyl group) enhance the formation and use of many reagents. For example, Grignard reagents cannot form unless an ether is present to share its lone pair of electrons with the magnesium atom. Complexation of the magnesium atom stabilizes the Grignard reagent and helps to keep it in solution.Category: ethers-buliding-blocks

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

O-alkyl-N-acyl-N-phenylhydroxylamines as photochemical alkoxy radical precursors was written by Chowdhury, Nilanjana;Anoop, Anakuthil;Singh, N. D. Pradeep. And the article was included in Synthesis in 2012.Computed Properties of C11H16O3 This article mentions the following:

A simple and efficient technique for the photolysis of alkoxy radical precursors is developed. Irradiation of O-alkyl-N-acyl-N-phenylhydroxylamines, as representative alkoxy radical precursors, with UV light (≥254 nm) results in homolytic N-O bond cleavage to generate singlet alkoxy and acylaminyl caged radical pairs. These radicals, depending on the solvent employed, either escape from the cage to form fragmentation products, or undergo in-cage reactions to produce photorearrangement products. The homolytic cleavage of the N-O bond is analyzed using time-dependent d. functional theory calculations The nature of the N-acyl substituent on the O-alkyl-N-acyl-N-phenylhydroxylamines is shown to influence their ability to generate radicals. Furthermore, identification and trapping of the alkoxy radicals is demonstrated. In the experiment, the researchers used many compounds, for example, 3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3Computed Properties of C11H16O3).

3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3) belongs to ethers. The oxygen atom in ethers are more electronegative than carbon, thus the hydrogens which are alpha to the ethers are more acidic than the simple hydrocarbons. Ethyl ether is an excellent solvent for extractions and for a wide variety of chemical reactions. It is also used as a volatile starting fluid for diesel engines and gasoline engines in cold weather. Dimethyl ether is used as a spray propellant and refrigerant. Methyl t-butyl ether (MTBE) is a gasoline additive that boosts the octane number and reduces the amount of nitrogen-oxide pollutants in the exhaust. The ethers of ethylene glycol are used as solvents and plasticizers.Computed Properties of C11H16O3

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Ether – Wikipedia,
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Studies on antiulcer agents. II. Synthesis and antiulcer activity of phenylpropanol derivatives was written by Muto, Yoshiaki;Ichikawa, Hiromi;Seiki, Masao;Shirataki, Yoshiaki;Yokoe, Ichiro;Komatsu, Manki. And the article was included in Yakugaku Zasshi in 1994.Synthetic Route of C11H16O3 This article mentions the following:

It was found that γ-irigermanal, obtained from the methanol extract of root of Iris germanica, exhibited a potent antiulcer activity. Therefore, this compound was selected as a lead-compound, and related compounds were synthesized and tested for antiulcer activities. It was found that (±) Et 2-[2-(3-hydroxypropyl)-4-oxocyclohexylidene]propionate (1) had excellent antiulcer activities. Then phenylpropanol derivatives, obtained by changing from cyclohexane ring of 1 to benzene ring, were synthesized and tested for antiulcer activities in order to study structure-activity relationships. As a result, (±) Et 2-[2-(3-hydroxypropyl)-4,5-dimethoxyphenyl]propionate (2b) and (±) 3-[2-(3-hydroxypropyl)-4,5-dimethoxyphenyl]-2-butanone (5) were shown to have antiulcer activities. In the experiment, the researchers used many compounds, for example, 3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3Synthetic Route of C11H16O3).

3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.Synthetic Route of C11H16O3

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

The effect of ortho-substitution on the efficacy of biphenyls in mediating electron transfer from lithium was written by Donohoe, Timothy J.;Kershaw, Neil M.;Baron, Ronan;Compton, Richard G.. And the article was included in Tetrahedron in 2009.Product Details of 3929-47-3 This article mentions the following:

A systematic study into the effect of increasing ortho-substitution of a range of biphenyls with respect to their ability to mediate electron transfer from Li metal is described. A synthetic study demonstrated the requirements for effective mediation. The electrochem. reduction of the mediators and of the 2 substrates was studied in THF, 0.1M TBAP, at Pt microelectrodes both at room temperature and at low temperature The formal potentials, E⁰_f extracted from the cyclic voltammograms, are in agreement with results of the synthetic study and computational calculations also provide a correlation. In the experiment, the researchers used many compounds, for example, 3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3Product Details of 3929-47-3).

3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil. The unique properties of ethers (i.e., that they are strongly polar, with nonbonding electron pairs but no hydroxyl group) enhance the formation and use of many reagents. For example, Grignard reagents cannot form unless an ether is present to share its lone pair of electrons with the magnesium atom. Complexation of the magnesium atom stabilizes the Grignard reagent and helps to keep it in solution.Product Details of 3929-47-3

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

An efficient entry to pyrrolo[1,2-b]isoquinolines and related systems through Parham cyclization was written by Ruiz, Javier;Ardeo, Ainhoa;Ignacio, Roberto;Sotomayor, Nuria;Lete, Esther. And the article was included in Tetrahedron in 2005.Category: ethers-buliding-blocks This article mentions the following:

Aryllithiums generated by lithium-iodine exchange underwent intramol. cyclization to give pyrrolo[1,2-b]isoquinolines, e.g, I, in high yields. The best results were obtained when Weinreb or morpholine amides were used as internal electrophiles. The procedure has been extended to the preparation of seven and eight membered rings, opening a route to benzazepine and benzazocine skeletons. In the experiment, the researchers used many compounds, for example, 3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3Category: ethers-buliding-blocks).

3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. Autoxidation is the spontaneous oxidation of a compound in air. In the presence of oxygen, ethers slowly autoxidize to form hydroperoxides and dialkyl peroxides. If concentrated or heated, these peroxides may explode. To prevent such explosions, ethers should be obtained in small quantities, kept in tightly sealed containers, and used promptly.Category: ethers-buliding-blocks

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Solid-phase synthesis of sulfamides was written by Esteve, Cristina;Vidal, Bernat. And the article was included in Tetrahedron Letters in 2002.Formula: C11H16O3 This article mentions the following:

A straightforward synthesis of diversely substituted sulfamides is described. The reaction of sulfamoylating agent 4-(dimethylamino)-1-[[[(1,1-dimethylethoxy)carbonyl]amino]sulfonyl]pyridinium inner salt with solid-phase bound amines to give polymer bound BOC-substituted sulfamides is described. Further N-alkylation is achieved under Mitsunobu conditions. Simultaneous deprotection and cleavage of the products leads to unsym. substituted sulfamides. In the experiment, the researchers used many compounds, for example, 3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3Formula: C11H16O3).

3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. But ether is more polar than alkenes. Ethyl ether is an excellent solvent for extractions and for a wide variety of chemical reactions. It is also used as a volatile starting fluid for diesel engines and gasoline engines in cold weather. Dimethyl ether is used as a spray propellant and refrigerant. Methyl t-butyl ether (MTBE) is a gasoline additive that boosts the octane number and reduces the amount of nitrogen-oxide pollutants in the exhaust. The ethers of ethylene glycol are used as solvents and plasticizers.Formula: C11H16O3

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Olefin saturation and acid reduction of 3,4-dimethoxycinnamic acid and derivatives by Phanerochaete chrysosporium was written by Enoki, Akio;Yajima, Yasuo;Gold, Michael H.. And the article was included in Phytochemistry (Elsevier) in 1981.Name: 3-(3,4-Dimethoxyphenyl)propan-1-ol This article mentions the following:

The white rot fungus P. chrysosporium metabolized 3,4-dimethoxycinnamic acid in shaking and N-sufficient cultures. Metabolites identified included 3-(3,4-dimethoxyphenyl)propionic acid, dimethoxycinnamyl alc. and 3-(3,4-dimethoxyphenyl)-1-propanol. Significantly smaller amounts of veratryl and vanillyl alc. were also present. The abundance of the propionic acid and the propanol as metabolic products indicated that olefin saturation and acid reduction are important reactions catalyzed under these conditions. Metabolites identified from the metabolism of 3-(3,4-dimethoxyphenyl)-propionic acid included the above 1-propanol as well as veratryl and vanillyl alc.; the identification of these benzyl alc. derivatives as metabolites suggests that α,β-bond cleavage of this substrate was preceded by alkane hydroxylation at the α-position. In the experiment, the researchers used many compounds, for example, 3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3Name: 3-(3,4-Dimethoxyphenyl)propan-1-ol).

3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3) belongs to ethers. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides. Ethers can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds.Name: 3-(3,4-Dimethoxyphenyl)propan-1-ol

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Monofluoro Analogs of Eugenol Methyl Ether as Novel Attractants for the Oriental Fruit Fly was written by Khrimian, Achot P.;DeMilo, Albert B.;Waters, Rolland M.;Liquido, Nicanor J.;Nicholson, Jesse M.. And the article was included in Journal of Organic Chemistry in 1994.COA of Formula: C11H16O3 This article mentions the following:

Monofluoro analogs of eugenol Me ether as potential attractants for the Oriental fruit fly (Bactrocera dorsalis, Hendel) were synthesized using selective fluorination reactions: electrophilic hydro- and iodofluorination, fluorodehydroxylation with (diethylamido)sulfur trifluoride (DAST), and Wittig fluoroolefination through the stabilized ylides. Unusual reduction of the double bond was detected in a reaction of Me eugenol with pyridinium poly(hydrogen fluoride). Bis[(3,4-dimethoxyphenyl)alkyl] carbonates were identified as the novel nucleophilic substitution products of the intermediate generated from the reaction of 3,4-dimethoxybenzenealkanols with DAST. Reductive desulfonylation of (Z)-3,4-(MeO)₂C₆H₃CH₂CH:CFSO₂Ph with sodium amalgam afforded 3,4-(MeO)₂C₆H₃CH₂CH:CHF (E/Z = 85:15) which was highly attractive to the Oriental fruit fly. In the experiment, the researchers used many compounds, for example, 3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3COA of Formula: C11H16O3).

3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. But on the other hand, ethers undergo cleavage by reaction with acids. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.COA of Formula: C11H16O3

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Dihydroconiferyl alcohol as a gibberellin synergist in inducing lettuce hypocotyl elongation. Assessment of structure-activity relationships was written by Shibata, Kozo;Kubota, Takashi;Kamisaka, Seiichiro. And the article was included in Plant and Cell Physiology in 1975.Recommanded Product: 3-(3,4-Dimethoxyphenyl)propan-1-ol This article mentions the following:

Structure-activity relationships of the cotyledon factor were examined by testing the effect of various substances structurally related to the cotyledon factor on gibberellin-induced lettuce hypocotyl elongation. The biol. activity of the cotyledon factor, 3-(4-hydroxy-3-methoxyphenyl) propan-1-ol [2305-13-7], disappeared if the phenolic hydroxy group was masked with a methoxy or glucosyl group. Oxidation of the alc. group in the side chain to a carboxylic group decreased the biol. activity of the cotyledon factor. As to relationships between the biol. activity and length of the alkyl side chain, the propane type was found to be much more active than the methane, ethane or butane type. The presence of a C:C bond in the alkyl side chain made the cotyledon factor biol. inactive. Some antioxidants of indole-3-acetic acid were also assayed for cotyledon factor-like activity, since the cotyledon factor is a polyphenol. However, known antioxidants such as rutin, pyrocatechol, chlorogenic acid, caffeic acid and ferulic acid did not show cotyledon factor-like activity. Structural requirements of the cotyledon factor as a gibberellin synergist were discussed. In the experiment, the researchers used many compounds, for example, 3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3Recommanded Product: 3-(3,4-Dimethoxyphenyl)propan-1-ol).

3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. Electron-deficient reagents are also stabilized by ethers. For example, borane (BH3) is a useful reagent for making alcohols. Pure borane exists as its dimer, diborane (B2H6), a toxic gas that is inconvenient and hazardous to use. Borane forms stable complexes with ethers, however, and it is often supplied and used as its liquid complex with tetrahydrofuran (THF).Recommanded Product: 3-(3,4-Dimethoxyphenyl)propan-1-ol

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem