Category: 38256-93-8

Ethers can again be classified into two varieties: if the alkyl or aryl groups are the same on both sides of the oxygen atom, 38256-93-8, formula is C4H11NO, Name is 2-Methoxy-N-methylethanamine. Then it is a simple or symmetrical ether, whereas if they are different, the ethers are called mixed or unsymmetrical ethers. Recommanded Product: 2-Methoxy-N-methylethanamine.

Isobe, Shin-ichi;Terasaki, Shou;Hanakawa, Taisyun;Mizuno, Shota;Kawatsura, Motoi research published 《 Ruthenium-catalyzed regioselective allylic amination of 2,3,3-trifluoroallylic carbonates》, the research content is summarized as follows. The ruthenium-catalyzed allylic amination of 2,3,3-trifluoroallylic carbonates R¹CH(OBoc)CF:CF₂ (R¹ = Ph, 4-trifluoromethylphenyl, 2-naphthyl, phenylethyl, etc.) with several types of amines such as benzylamine, indoline, methylbenzylamine, N-methylpiperazine, etc. has been demonstrated. The reactions proceeded with several types of amines, and succeeded in obtaining polyfluorinated terminal alkenes possessing branched allylic amines R¹R²CHCF:CF₂ (R² = benzylamino, indol-1-yl, methylbenzylamino, N-methylpiperazin-4-yl, etc.) as a single regioisomer.

Recommanded Product: 2-Methoxy-N-methylethanamine, 2-Methoxy-N-methylethanamine is a useful research compound. Its molecular formula is C4H11NO and its molecular weight is 89.14 g/mol. The purity is usually 95%.
2-Methoxy-N-methylethanamine is a drug that binds to the cannabinoid receptor CB1. It has been shown to be effective in the treatment of cardiac arrhythmia and may also be used as an anti-inflammatory drug. 2MEMEA has been shown to have pharmacokinetic properties that are different from those of other amines, which may be due to its ability to form hydrogen bonds with water molecules. 2MEMEA also has diversified effects on some types of cancer cells, including hyperproliferative and amine-dependent cancers., 38256-93-8.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers are a class of organic compounds that contain an ether group—an oxygen atom connected to two alkyl or aryl groups. 38256-93-8, formula is C4H11NO, Name is 2-Methoxy-N-methylethanamine.They have the general formula R–O–R′, where R and R′ represent the alkyl or aryl groups. Application In Synthesis of 38256-93-8.

Izzo, Flavia;Schaefer, Martina;Stockman, Robert;Luecking, Ulrich research published 《 A New, Practical One-Pot Synthesis of Unprotected Sulfonimidamides by Transfer of Electrophilic NH to Sulfinamides》, the research content is summarized as follows. Unprotected tertiary sulfonimidamides RS(O)(=NH)X (R = Ph, (CH₃)₂CH, cyclohexyl, 2-pyridyl, etc.; X = 1-piperidinyl, N(CH₃)₂, (CH₃)N(CH₂)₂OCH₃, etc.) have been prepared in good to excellent yields in a one-pot transformation from tertiary sulfinamides RS(O)X through NH transfer. The reaction is mediated by com. available (diacetoxyiodo)benzene and ammonium carbamate in methanol under convenient conditions. A wide range of functional groups is tolerated and initial results indicate that the NH transfer is stereospecific. A small mol. X-ray anal. of 1-(S-phenylsulfonimidoyl)piperidine and its behavior in selected in vitro assays in comparison to the matched 1-benzenesulfonyl-piperidine are also reported. This new reaction provides a safe, short and efficient approach to sulfonimidamides, which have been the subject of recent, growing interest in the life sciences.

38256-93-8, 2-Methoxy-N-methylethanamine is a useful research compound. Its molecular formula is C4H11NO and its molecular weight is 89.14 g/mol. The purity is usually 95%.
2-Methoxy-N-methylethanamine is a drug that binds to the cannabinoid receptor CB1. It has been shown to be effective in the treatment of cardiac arrhythmia and may also be used as an anti-inflammatory drug. 2MEMEA has been shown to have pharmacokinetic properties that are different from those of other amines, which may be due to its ability to form hydrogen bonds with water molecules. 2MEMEA also has diversified effects on some types of cancer cells, including hyperproliferative and amine-dependent cancers., Application In Synthesis of 38256-93-8

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers can again be classified into two varieties: if the alkyl or aryl groups are the same on both sides of the oxygen atom, 38256-93-8, formula is C4H11NO, Name is 2-Methoxy-N-methylethanamine. Then it is a simple or symmetrical ether, whereas if they are different, the ethers are called mixed or unsymmetrical ethers. Product Details of C4H11NO.

Johnson, Ted W.;Tanis, Steven P.;Butler, Scott L.;Dalvie, Deepak;DeLisle, Dorothy M.;Dress, Klaus R.;Flahive, Erik J.;Hu, Qiyue;Kuehler, Jon E.;Kuki, Atsuo;Liu, Wen;McClellan, Guy A.;Peng, Qinghai;Plewe, Michael B.;Richardson, Paul F.;Smith, Graham L.;Solowiej, Jim;Tran, Khanh T.;Wang, Hai;Yu, Xiaoming;Zhang, Junhu;Zhu, Huichun research published 《 Design and Synthesis of Novel N-Hydroxy-Dihydronaphthyridinones as Potent and Orally Bioavailable HIV-1 Integrase Inhibitors》, the research content is summarized as follows. HIV-1 integrase (IN) is one of three enzymes encoded by the HIV genome and is essential for viral replication, and HIV-1 IN inhibitors have emerged as a new promising class of therapeutics. Recently, we reported the synthesis of orally bioavailable azaindole hydroxamic acids that were potent inhibitors of the HIV-1 IN enzyme. Here we disclose the design and synthesis of novel tricyclic N-hydroxy-dihydronaphthyridinones, e.g., I, as potent, orally bioavailable HIV-1 integrase inhibitors displaying excellent ligand and lipophilic efficiencies.

38256-93-8, 2-Methoxy-N-methylethanamine is a useful research compound. Its molecular formula is C4H11NO and its molecular weight is 89.14 g/mol. The purity is usually 95%.
2-Methoxy-N-methylethanamine is a drug that binds to the cannabinoid receptor CB1. It has been shown to be effective in the treatment of cardiac arrhythmia and may also be used as an anti-inflammatory drug. 2MEMEA has been shown to have pharmacokinetic properties that are different from those of other amines, which may be due to its ability to form hydrogen bonds with water molecules. 2MEMEA also has diversified effects on some types of cancer cells, including hyperproliferative and amine-dependent cancers., Product Details of C4H11NO

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers are a class of organic compounds that contain an ether group—an oxygen atom connected to two alkyl or aryl groups. 38256-93-8, formula is C4H11NO, Name is 2-Methoxy-N-methylethanamine.They have the general formula R–O–R′, where R and R′ represent the alkyl or aryl groups. Related Products of 38256-93-8.

Han, Dongyang;Li, Sasa;Xia, Siqi;Su, Mincong;Jin, Jian research published 《 Nickel-Catalyzed Amination of (Hetero)aryl Halides Facilitated by a Catalytic Pyridinium Additive》, the research content is summarized as follows. An efficient and operationally simple Ni-catalyzed amination protocol has been developed. This methodol. features a simple Ni^II salt, an organic base and catalytic amounts of both a pyridinium additive and Zn metal. A diverse number of (hetero)aryl halides RX (R = 4-methanesulfonylphenyl, 3-cyanopyridin-2-yl, 1,3-benzoxazol-2-yl, etc.; X = Br, Cl) were coupled successfully with primary and secondary alkyl amines and anilines such as cyclohexanamine, pyrrolidine, 4-methylaniline, etc. in good to excellent yields RR¹ [R¹ = cyclohexylaminyl, pyrrolidin-1-yl, (4-methylphenyl)aminyl, etc.]. Similarly, benzophenone imine gave the corresponding N-arylation product N-(4-(methylsulfonyl)phenyl)-1,1-diphenylmethanimine in an excellent yield.

38256-93-8, 2-Methoxy-N-methylethanamine is a useful research compound. Its molecular formula is C4H11NO and its molecular weight is 89.14 g/mol. The purity is usually 95%.
2-Methoxy-N-methylethanamine is a drug that binds to the cannabinoid receptor CB1. It has been shown to be effective in the treatment of cardiac arrhythmia and may also be used as an anti-inflammatory drug. 2MEMEA has been shown to have pharmacokinetic properties that are different from those of other amines, which may be due to its ability to form hydrogen bonds with water molecules. 2MEMEA also has diversified effects on some types of cancer cells, including hyperproliferative and amine-dependent cancers., Related Products of 38256-93-8

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers lack the hydroxyl groups of alcohols. Without the strongly polarized O―H bond, ether molecules cannot engage in hydrogen bonding with each other. 38256-93-8, formula is C4H11NO, Name is 2-Methoxy-N-methylethanamine. Ethers do have nonbonding electron pairs on their oxygen atoms, however, and they can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. Application of C4H11NO.

Herdemann, Matthias;Weber, Alexander;Jonveaux, Jerome;Schwoebel, Frank;Stoeck, Michael;Heit, Isabelle research published 《 Optimisation of ITK inhibitors through successive iterative design cycles》, the research content is summarized as follows. Based on a hit cluster of compounds inhibiting interleukin-2 inducible T-cell kinase (ITK) in the submicromolar range a series of ITK inhibitor libraries were synthesized. Through iterative design cycles including kinase crystal structure information, indolylindazole libraries were identified which showed low nanomolar activity in enzymic and cellular assays. The potential of these novel lead series was confirmed through in vivo tests in an anti-CD3-IL2 mouse model. The i.v. administration of highly potent ITK inhibitor I resulted in dose-dependent, efficient suppression of IL-2.

Application of C4H11NO, 2-Methoxy-N-methylethanamine is a useful research compound. Its molecular formula is C4H11NO and its molecular weight is 89.14 g/mol. The purity is usually 95%.
2-Methoxy-N-methylethanamine is a drug that binds to the cannabinoid receptor CB1. It has been shown to be effective in the treatment of cardiac arrhythmia and may also be used as an anti-inflammatory drug. 2MEMEA has been shown to have pharmacokinetic properties that are different from those of other amines, which may be due to its ability to form hydrogen bonds with water molecules. 2MEMEA also has diversified effects on some types of cancer cells, including hyperproliferative and amine-dependent cancers., 38256-93-8.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers are a class of organic compounds that contain an ether group—an oxygen atom connected to two alkyl or aryl groups. 38256-93-8, formula is C4H11NO, Name is 2-Methoxy-N-methylethanamine.They have the general formula R–O–R′, where R and R′ represent the alkyl or aryl groups. Application In Synthesis of 38256-93-8.

Hoelzel, Conner A.;Hu, Hang;Wolstenholme, Charles H.;Karim, Basel A.;Munson, Kyle T.;Jung, Kwan Ho;Zhang, Han;Liu, Yu;Yennawar, Hemant P.;Asbury, John B.;Li, Xiaosong;Zhang, Xin research published 《 A General Strategy to Enhance Donor-Acceptor Molecules Using Solvent-Excluding Substituents》, the research content is summarized as follows. While organic donor-acceptor (D-A) mols. are widely employed in multiple areas, the application of more D-A mols. could be limited because of an inherent polarity sensitivity that inhibits photochem. processes. Presented here is a facile chem. modification to attenuate solvent-dependent mechanisms of excited-state quenching through addition of a β-carbonyl-based polar substituent. The results reveal a mechanism wherein the β-carbonyl substituent creates a structural buffer between the donor and the surrounding solvent. Through computational and exptl. analyses, it is demonstrated that the β-carbonyl simultaneously attenuates two distinct solvent-dependent quenching mechanisms. Using the β-carbonyl substituent, improvements in the photophys. properties of commonly used D-A fluorophores and their enhanced performance in biol. imaging are shown.

38256-93-8, 2-Methoxy-N-methylethanamine is a useful research compound. Its molecular formula is C4H11NO and its molecular weight is 89.14 g/mol. The purity is usually 95%.
2-Methoxy-N-methylethanamine is a drug that binds to the cannabinoid receptor CB1. It has been shown to be effective in the treatment of cardiac arrhythmia and may also be used as an anti-inflammatory drug. 2MEMEA has been shown to have pharmacokinetic properties that are different from those of other amines, which may be due to its ability to form hydrogen bonds with water molecules. 2MEMEA also has diversified effects on some types of cancer cells, including hyperproliferative and amine-dependent cancers., Application In Synthesis of 38256-93-8

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers do have nonbonding electron pairs on their oxygen atoms, 38256-93-8, formula is C4H11NO, Name is 2-Methoxy-N-methylethanamine. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds. Related Products of 38256-93-8.

Holmes, Jane L.;Almeida, Lynsie;Barlaam, Bernard;Croft, Rosemary A.;Dishington, Allan P.;Gingipalli, Laksmaiah;Hassall, Lorraine A.;Hawkins, Janet L.;Ioannidis, Stephanos;Johannes, Jeffrey W.;McGuire, Thomas M.;Moore, Jane E.;Patel, Anil;Pike, Kurt G.;Pontz, Timothy;Wu, Xiaoyun;Wang, Tao;Zhang, Hai-Jun;Zheng, Xiaolan research published 《 Synthesis of Novel Hydroxymethyl-Substituted Fused Heterocycles》, the research content is summarized as follows. Examples of hydroxymethylated analogs of heteroaryl cores such as quinazolin-4-ones, isoquinolin-1(2H)-ones, pyrido[3,4-d]pyrimidin-4(3H)-ones, chromen-4-ones and pyrrolo[2,1-f][1,2,4]triazin-4(3H)-ones were sparse or non-existent in the scientific literature. Synthesis of such compounds by using standard procedures from readily available raw materials was demonstrated.

Related Products of 38256-93-8, 2-Methoxy-N-methylethanamine is a useful research compound. Its molecular formula is C4H11NO and its molecular weight is 89.14 g/mol. The purity is usually 95%.
2-Methoxy-N-methylethanamine is a drug that binds to the cannabinoid receptor CB1. It has been shown to be effective in the treatment of cardiac arrhythmia and may also be used as an anti-inflammatory drug. 2MEMEA has been shown to have pharmacokinetic properties that are different from those of other amines, which may be due to its ability to form hydrogen bonds with water molecules. 2MEMEA also has diversified effects on some types of cancer cells, including hyperproliferative and amine-dependent cancers., 38256-93-8.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. 38256-93-8, formula is C4H11NO, Name is 2-Methoxy-N-methylethanamine. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3. Computed Properties of 38256-93-8.

Hu, Lingling;Yu, Shanshan;Wang, Yachen;Yu, Xiaoqi;Pu, Lin research published 《 Enhanced Fluorescence of 3,3′-Diformyl BINOL by Functional Secondary Amines》, the research content is summarized as follows. Although 3,3′-diformyl-BINOL (S)-I shows little change in its fluorescence when treated with primary amines, its fluorescence can be greatly enhanced by using functional secondary amines including β- and γ-amino alcs. and 1,2- and 1,3-bis(secondary amine) compounds It has been demonstrated that the functional secondary amines react with (S)-I to convert the conjugated aldehyde groups to unconjugated oxazolidines or aminals to turn on the fluorescence.

Computed Properties of 38256-93-8, 2-Methoxy-N-methylethanamine is a useful research compound. Its molecular formula is C4H11NO and its molecular weight is 89.14 g/mol. The purity is usually 95%.
2-Methoxy-N-methylethanamine is a drug that binds to the cannabinoid receptor CB1. It has been shown to be effective in the treatment of cardiac arrhythmia and may also be used as an anti-inflammatory drug. 2MEMEA has been shown to have pharmacokinetic properties that are different from those of other amines, which may be due to its ability to form hydrogen bonds with water molecules. 2MEMEA also has diversified effects on some types of cancer cells, including hyperproliferative and amine-dependent cancers., 38256-93-8.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers do have nonbonding electron pairs on their oxygen atoms, 38256-93-8, formula is C4H11NO, Name is 2-Methoxy-N-methylethanamine. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds. Quality Control of 38256-93-8.

Fu, Jiping;Tjandra, Meiliana;Becker, Christopher;Bednarczyk, Dallas;Capparelli, Michael;Elling, Robert;Hanna, Imad;Fujimoto, Roger;Furegati, Markus;Karur, Subramanian;Kasprzyk, Theresa;Knapp, Mark;Leung, Kwan;Li, Xiaolin;Lu, Peichao;Mergo, Wosenu;Miault, Charlotte;Ng, Simon;Parker, David;Peng, Yunshan;Roggo, Silvio;Rivkin, Alexey;Simmons, Robert L.;Wang, Michael;Wiedmann, Brigitte;Weiss, Andrew H.;Xiao, Linda;Xie, Lili;Xu, Wenjian;Yifru, Aregahegn;Yang, Shengtian;Zhou, Bo;Sweeney, Zachary K. research published 《 Potent Nonimmunosuppressive Cyclophilin Inhibitors With Improved Pharmaceutical Properties and Decreased Transporter Inhibition》, the research content is summarized as follows. Nonimmunosuppressive cyclophilin inhibitors have demonstrated efficacy for the treatment of hepatitis C infection (HCV). However, alisporivir, cyclosporin A, and most other cyclosporins are potent inhibitors of OATP1B1, MRP2, MDR1, and other important drug transporters. Reduction of the side chain hydrophobicity of the P4 residue preserves cyclophilin binding and antiviral potency while decreasing transporter inhibition. Representative inhibitor 33 (NIM258) is a less potent transporter inhibitor relative to previously described cyclosporins, retains anti-HCV activity in cell culture, and has an acceptable pharmacokinetic profile in rats and dogs. An X-ray structure of 33 bound to rat cyclophilin D is reported.

Quality Control of 38256-93-8, 2-Methoxy-N-methylethanamine is a useful research compound. Its molecular formula is C4H11NO and its molecular weight is 89.14 g/mol. The purity is usually 95%.
2-Methoxy-N-methylethanamine is a drug that binds to the cannabinoid receptor CB1. It has been shown to be effective in the treatment of cardiac arrhythmia and may also be used as an anti-inflammatory drug. 2MEMEA has been shown to have pharmacokinetic properties that are different from those of other amines, which may be due to its ability to form hydrogen bonds with water molecules. 2MEMEA also has diversified effects on some types of cancer cells, including hyperproliferative and amine-dependent cancers., 38256-93-8.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers are a class of organic compounds that contain an ether group—an oxygen atom connected to two alkyl or aryl groups. 38256-93-8, formula is C4H11NO, Name is 2-Methoxy-N-methylethanamine.They have the general formula R–O–R′, where R and R′ represent the alkyl or aryl groups. Application of C4H11NO.

Gabriel, Lars;Gericke, Martin;Heinze, Thomas research published 《 Modular synthesis of non-charged and ionic xylan carbamate derivatives from xylan carbonates》, the research content is summarized as follows. Non-charged and ionic xylan carbamate (XC) derivatives were synthesized in a modular approach from xylan Ph carbonates (XPC) as reactive intermediates. XPC with varying degrees of substitution (DS) from 0.5 to 1.9 were converted with different non-ionic primary and secondary amines in different molar ratio to obtain the corresponding XC with high conversion rates of up to 100%. In a similar way, ionic amines were employed for the aminolysis of XPC to obtain charged XC. The XC were characterized by NMR and IR spectroscopy. XPC were proofed to be highly versatile building blocks for the preparation of ionic xylan derivatives The type and amount of charged groups could be tuned efficiently. DS values of up to 1.4 for cationic and 1.8 for anionic XC derivatives could be achieved, which is higher than reported results obtained by esterification and etherification reactions.

38256-93-8, 2-Methoxy-N-methylethanamine is a useful research compound. Its molecular formula is C4H11NO and its molecular weight is 89.14 g/mol. The purity is usually 95%.
2-Methoxy-N-methylethanamine is a drug that binds to the cannabinoid receptor CB1. It has been shown to be effective in the treatment of cardiac arrhythmia and may also be used as an anti-inflammatory drug. 2MEMEA has been shown to have pharmacokinetic properties that are different from those of other amines, which may be due to its ability to form hydrogen bonds with water molecules. 2MEMEA also has diversified effects on some types of cancer cells, including hyperproliferative and amine-dependent cancers., Application of C4H11NO

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem