Category: 38256-93-8

Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. 38256-93-8, formula is C4H11NO, Name is 2-Methoxy-N-methylethanamine. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3. Related Products of 38256-93-8.

Lang, Simon B.;Wiles, Rebecca J.;Kelly, Christopher B.;Molander, Gary A. research published ã€?Photoredox Generation of Carbon-Centered Radicals Enables the Construction of 1,1-Difluoroalkene Carbonyl Mimicsã€? the research content is summarized as follows. 1,1-Disubstituted trifluoromethylalkenes such as I underwent photochem. alkylation and defluorination with aminomethylsilanes such as 4-(trimethylsilylmethyl)thiomorpholine, potassium trifluoroborates such as t-BuBF₃^–K⁺, or bis(catecholate)silicates in the presence of either a tetrakis(carbazolyl)benzenedicarbonitrile photocatalyst or Ru(bpy)₃(PF₆)₂ in either DMF or DMSO under blue LED irradiation to yield difluoroalkenes such as II [R = 4-thiomorpholinyl, t-Bu, MeO(CH₂)₃]. Nonstabilized primary, secondary, and tertiary radicals generated from silanes, trifluoroborates, or silicates were used to install functional groups which would otherwise be challenging or would require extended syntheses using two-electron pathways. Difluoromethyl and pentafluoroethyl alkenes underwent analogous photochem. defluorinative alkylations to yield fluoroalkenes and trifluoromethylfluoroalkenes, resp. The trifluoropropenyltrifluoroborate reagent F₃CC(:CH₂)BF₃^–K⁺ was prepared as a convenient reagent for the preparation of trifluoromethyl alkenes amenable to defluorinative alkylation sequences.

Related Products of 38256-93-8, 2-Methoxy-N-methylethanamine is a useful research compound. Its molecular formula is C4H11NO and its molecular weight is 89.14 g/mol. The purity is usually 95%.
2-Methoxy-N-methylethanamine is a drug that binds to the cannabinoid receptor CB1. It has been shown to be effective in the treatment of cardiac arrhythmia and may also be used as an anti-inflammatory drug. 2MEMEA has been shown to have pharmacokinetic properties that are different from those of other amines, which may be due to its ability to form hydrogen bonds with water molecules. 2MEMEA also has diversified effects on some types of cancer cells, including hyperproliferative and amine-dependent cancers., 38256-93-8.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers lack the hydroxyl groups of alcohols. Without the strongly polarized O―H bond, ether molecules cannot engage in hydrogen bonding with each other. 38256-93-8, formula is C4H11NO, Name is 2-Methoxy-N-methylethanamine. Ethers do have nonbonding electron pairs on their oxygen atoms, however, and they can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. Product Details of C4H11NO.

Kim, In-Hae;Kanayama, Yoshiki;Nishiwaki, Hisashi;Sugahara, Takuya;Nishi, Kosuke research published ã€?Structure-Activity Relationships of Fish Oil Derivatives with Antiallergic Activity in Vitro and in Vivoã€? the research content is summarized as follows. A series of unsaturated fatty acids in fish oil and their corresponding ethanolamide metabolites were explored to find active fish oil components of antiallergic activity in vitro. Ethanolamides of omega-3 fatty acids (α-linolenic acid, EPA, and DHA) were found to possess promising antiallergic activity, whereas free fatty acids and ethanolamides of other fatty acids exhibited no or weak potency. Based on this finding, structure-activity relationships of DHA-ethanolamide (DHEA) derivatives were investigated to yield better fatty acid derivatives with enhanced antiallergic activity in vitro and in vivo. When the ethanolamide moiety of DHEA was replaced by the substituted sulfonamide functionality, highly promising potency was provided in vitro. Compound 59 showed improved antiallergic activity in vivo over DHEA. The results indicate that optimized DHEA derivatives have enhanced antiallergic activity in vitro and in vivo, and the resulting structures will be an important basis for further development of bioavailable derivatives with promising allergy suppressive activity.

38256-93-8, 2-Methoxy-N-methylethanamine is a useful research compound. Its molecular formula is C4H11NO and its molecular weight is 89.14 g/mol. The purity is usually 95%.
2-Methoxy-N-methylethanamine is a drug that binds to the cannabinoid receptor CB1. It has been shown to be effective in the treatment of cardiac arrhythmia and may also be used as an anti-inflammatory drug. 2MEMEA has been shown to have pharmacokinetic properties that are different from those of other amines, which may be due to its ability to form hydrogen bonds with water molecules. 2MEMEA also has diversified effects on some types of cancer cells, including hyperproliferative and amine-dependent cancers., Product Details of C4H11NO

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers lack the hydroxyl groups of alcohols. Without the strongly polarized O―H bond, ether molecules cannot engage in hydrogen bonding with each other. 38256-93-8, formula is C4H11NO, Name is 2-Methoxy-N-methylethanamine. Ethers do have nonbonding electron pairs on their oxygen atoms, however, and they can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. Product Details of C4H11NO.

Kiyoi, Takao;Adam, Julia M.;Clark, John K.;Davies, Keneth;Easson, Anna-Marie;Edwards, Darren;Feilden, Helen;Fields, Ruth;Francis, Stuart;Jeremiah, Fiona;McArthur, Duncan;Morrison, Angus J.;Prosser, Alan;Ratcliffe, Paul D.;Schulz, Jurgen;Wishart, Grant;Baker, James;Campbell, Robert;Cottney, Jean E.;Deehan, Maureen;Epemolu, Ola;Evans, Louise research published �Discovery of potent and orally bioavailable heterocycle-based cannabinoid CB1 receptor agonists� the research content is summarized as follows. Novel 3-(1H-indol-3-yl)-1,2,4-oxadiazoles e. g., I and -thiadiazoles e. g., II were synthesized and found to be potent CB1 cannabinoid receptor agonists. The oral bioavailability of these compounds could be dramatically improved by optimization studies of the side chains attached to the indole and oxadiazole cores, leading to identification of a CB1 receptor agonist with good oral activity in a range of preclin. models of antinociception and antihyperalgesia.

Product Details of C4H11NO, 2-Methoxy-N-methylethanamine is a useful research compound. Its molecular formula is C4H11NO and its molecular weight is 89.14 g/mol. The purity is usually 95%.
2-Methoxy-N-methylethanamine is a drug that binds to the cannabinoid receptor CB1. It has been shown to be effective in the treatment of cardiac arrhythmia and may also be used as an anti-inflammatory drug. 2MEMEA has been shown to have pharmacokinetic properties that are different from those of other amines, which may be due to its ability to form hydrogen bonds with water molecules. 2MEMEA also has diversified effects on some types of cancer cells, including hyperproliferative and amine-dependent cancers., 38256-93-8.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers do have nonbonding electron pairs on their oxygen atoms, 38256-93-8, formula is C4H11NO, Name is 2-Methoxy-N-methylethanamine. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds. Recommanded Product: 2-Methoxy-N-methylethanamine.

Labroli, Marc A.;Dwyer, Michael P.;Shen, Ruichao;Popovici-Muller, Janeta;Pu, Qinglin;Richard, Judson;Rosner, Kristen;Paruch, Kamil;Guzi, Timothy J. research published ã€?Syntheses of 5′-amino-2′,5′-dideoxy-2′,2′-difluorocytidine derivatives as novel anticancer nucleoside analogsã€? the research content is summarized as follows. A novel class of 5′-amino-2′,5′-dideoxy-2′,2′-difluorocytidine derivatives, e.g. I, has been synthesized in order to identify anticancer nucleoside analogs. Several synthetic routes were devised and implemented which relied upon either S_N2 displacement or reductive amination to provide the desired derivatives

Recommanded Product: 2-Methoxy-N-methylethanamine, 2-Methoxy-N-methylethanamine is a useful research compound. Its molecular formula is C4H11NO and its molecular weight is 89.14 g/mol. The purity is usually 95%.
2-Methoxy-N-methylethanamine is a drug that binds to the cannabinoid receptor CB1. It has been shown to be effective in the treatment of cardiac arrhythmia and may also be used as an anti-inflammatory drug. 2MEMEA has been shown to have pharmacokinetic properties that are different from those of other amines, which may be due to its ability to form hydrogen bonds with water molecules. 2MEMEA also has diversified effects on some types of cancer cells, including hyperproliferative and amine-dependent cancers., 38256-93-8.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers lack the hydroxyl groups of alcohols. Without the strongly polarized O―H bond, ether molecules cannot engage in hydrogen bonding with each other. 38256-93-8, formula is C4H11NO, Name is 2-Methoxy-N-methylethanamine. Ethers do have nonbonding electron pairs on their oxygen atoms, however, and they can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. Product Details of C4H11NO.

Kim, In-Hae;Kanayama, Yoshiki;Nishiwaki, Hisashi;Sugahara, Takuya;Nishi, Kosuke research published ã€?Structure-Activity Relationships of Fish Oil Derivatives with Antiallergic Activity in Vitro and in Vivoã€? the research content is summarized as follows. A series of unsaturated fatty acids in fish oil and their corresponding ethanolamide metabolites were explored to find active fish oil components of antiallergic activity in vitro. Ethanolamides of omega-3 fatty acids (α-linolenic acid, EPA, and DHA) were found to possess promising antiallergic activity, whereas free fatty acids and ethanolamides of other fatty acids exhibited no or weak potency. Based on this finding, structure-activity relationships of DHA-ethanolamide (DHEA) derivatives were investigated to yield better fatty acid derivatives with enhanced antiallergic activity in vitro and in vivo. When the ethanolamide moiety of DHEA was replaced by the substituted sulfonamide functionality, highly promising potency was provided in vitro. Compound 59 showed improved antiallergic activity in vivo over DHEA. The results indicate that optimized DHEA derivatives have enhanced antiallergic activity in vitro and in vivo, and the resulting structures will be an important basis for further development of bioavailable derivatives with promising allergy suppressive activity.

38256-93-8, 2-Methoxy-N-methylethanamine is a useful research compound. Its molecular formula is C4H11NO and its molecular weight is 89.14 g/mol. The purity is usually 95%.
2-Methoxy-N-methylethanamine is a drug that binds to the cannabinoid receptor CB1. It has been shown to be effective in the treatment of cardiac arrhythmia and may also be used as an anti-inflammatory drug. 2MEMEA has been shown to have pharmacokinetic properties that are different from those of other amines, which may be due to its ability to form hydrogen bonds with water molecules. 2MEMEA also has diversified effects on some types of cancer cells, including hyperproliferative and amine-dependent cancers., Product Details of C4H11NO

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers lack the hydroxyl groups of alcohols. Without the strongly polarized O―H bond, ether molecules cannot engage in hydrogen bonding with each other. 38256-93-8, formula is C4H11NO, Name is 2-Methoxy-N-methylethanamine. Ethers do have nonbonding electron pairs on their oxygen atoms, however, and they can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. Product Details of C4H11NO.

Kiyoi, Takao;Adam, Julia M.;Clark, John K.;Davies, Keneth;Easson, Anna-Marie;Edwards, Darren;Feilden, Helen;Fields, Ruth;Francis, Stuart;Jeremiah, Fiona;McArthur, Duncan;Morrison, Angus J.;Prosser, Alan;Ratcliffe, Paul D.;Schulz, Jurgen;Wishart, Grant;Baker, James;Campbell, Robert;Cottney, Jean E.;Deehan, Maureen;Epemolu, Ola;Evans, Louise research published �Discovery of potent and orally bioavailable heterocycle-based cannabinoid CB1 receptor agonists� the research content is summarized as follows. Novel 3-(1H-indol-3-yl)-1,2,4-oxadiazoles e. g., I and -thiadiazoles e. g., II were synthesized and found to be potent CB1 cannabinoid receptor agonists. The oral bioavailability of these compounds could be dramatically improved by optimization studies of the side chains attached to the indole and oxadiazole cores, leading to identification of a CB1 receptor agonist with good oral activity in a range of preclin. models of antinociception and antihyperalgesia.

Product Details of C4H11NO, 2-Methoxy-N-methylethanamine is a useful research compound. Its molecular formula is C4H11NO and its molecular weight is 89.14 g/mol. The purity is usually 95%.
2-Methoxy-N-methylethanamine is a drug that binds to the cannabinoid receptor CB1. It has been shown to be effective in the treatment of cardiac arrhythmia and may also be used as an anti-inflammatory drug. 2MEMEA has been shown to have pharmacokinetic properties that are different from those of other amines, which may be due to its ability to form hydrogen bonds with water molecules. 2MEMEA also has diversified effects on some types of cancer cells, including hyperproliferative and amine-dependent cancers., 38256-93-8.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers do have nonbonding electron pairs on their oxygen atoms, 38256-93-8, formula is C4H11NO, Name is 2-Methoxy-N-methylethanamine. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds. Recommanded Product: 2-Methoxy-N-methylethanamine.

Labroli, Marc A.;Dwyer, Michael P.;Shen, Ruichao;Popovici-Muller, Janeta;Pu, Qinglin;Richard, Judson;Rosner, Kristen;Paruch, Kamil;Guzi, Timothy J. research published ã€?Syntheses of 5′-amino-2′,5′-dideoxy-2′,2′-difluorocytidine derivatives as novel anticancer nucleoside analogsã€? the research content is summarized as follows. A novel class of 5′-amino-2′,5′-dideoxy-2′,2′-difluorocytidine derivatives, e.g. I, has been synthesized in order to identify anticancer nucleoside analogs. Several synthetic routes were devised and implemented which relied upon either S_N2 displacement or reductive amination to provide the desired derivatives

Recommanded Product: 2-Methoxy-N-methylethanamine, 2-Methoxy-N-methylethanamine is a useful research compound. Its molecular formula is C4H11NO and its molecular weight is 89.14 g/mol. The purity is usually 95%.
2-Methoxy-N-methylethanamine is a drug that binds to the cannabinoid receptor CB1. It has been shown to be effective in the treatment of cardiac arrhythmia and may also be used as an anti-inflammatory drug. 2MEMEA has been shown to have pharmacokinetic properties that are different from those of other amines, which may be due to its ability to form hydrogen bonds with water molecules. 2MEMEA also has diversified effects on some types of cancer cells, including hyperproliferative and amine-dependent cancers., 38256-93-8.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers are a class of organic compounds that contain an ether group—an oxygen atom connected to two alkyl or aryl groups. 38256-93-8, formula is C4H11NO, Name is 2-Methoxy-N-methylethanamine.They have the general formula R–O–R′, where R and R′ represent the alkyl or aryl groups. Formula: C4H11NO.

Kawatsura, Motoi;Uchida, Kenta;Terasaki, Shou;Tsuji, Hiroaki;Minakawa, Maki;Itoh, Toshiyuki research published 《 Ruthenium-Catalyzed Regio- and Enantioselective Allylic Amination of Racemic 1-Arylallyl Esters》, the research content is summarized as follows. The regio- and enantioselective allylic amination of racemic monosubstituted allylic esters, such as 1-arylallyl acetates, with cyclic secondary amines has been accomplished. The RuCl₃/(S,S)-i.p.-pybox catalyst system has effectively catalyzed the reaction to afford the enantiomerically enriched branch-type allylic amines with perfect regioselectivity and high enantioselectivity.

Formula: C4H11NO, 2-Methoxy-N-methylethanamine is a useful research compound. Its molecular formula is C4H11NO and its molecular weight is 89.14 g/mol. The purity is usually 95%.
2-Methoxy-N-methylethanamine is a drug that binds to the cannabinoid receptor CB1. It has been shown to be effective in the treatment of cardiac arrhythmia and may also be used as an anti-inflammatory drug. 2MEMEA has been shown to have pharmacokinetic properties that are different from those of other amines, which may be due to its ability to form hydrogen bonds with water molecules. 2MEMEA also has diversified effects on some types of cancer cells, including hyperproliferative and amine-dependent cancers., 38256-93-8.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers are a class of organic compounds that contain an ether group—an oxygen atom connected to two alkyl or aryl groups. 38256-93-8, formula is C4H11NO, Name is 2-Methoxy-N-methylethanamine.They have the general formula R–O–R′, where R and R′ represent the alkyl or aryl groups. Product Details of C4H11NO.

Illig, Carl R.;Manthey, Carl L.;Meegalla, Sanath K.;Wall, Mark J.;Chen, Jinsheng;Wilson, Kenneth J.;DesJarlais, Renee L.;Ballentine, Shelley K.;Schubert, Carsten;Crysler, Carl S.;Chen, Yanmin;Molloy, Christopher J.;Chaikin, Margery A.;Donatelli, Robert R.;Yurkow, Edward;Zhou, Zhao;Player, Mark R.;Tomczuk, Bruce E. research published 《 Enhancement of kinase selectivity in a potent class of arylamide FMS inhibitors》, the research content is summarized as follows. Structure-activity relationship (SAR) studies on a highly potent series of arylamide FMS inhibitors were carried out with the aim of improving FMS kinase selectivity, particularly over KIT. Potent compound I [R = 4-(HOCH₂CH₂)piperazin-1-yl] (FMS IC₅₀ 0.7 nM, FMS cell IC₅₀ 6.1 nM) was discovered that had good PK properties and a greater than fivefold improvement in selectivity for FMS over KIT kinase in a cellular assay relative to the previously reported clin. candidate 4. This improved selectivity was manifested in vivo by no observed decrease in circulating reticulocytes, a measure of bone safety, at the highest studied dose. Compound I [R = 4-(HOCH₂CH₂)piperazin-1-yl] was highly active in a mouse pharmacodynamic model and demonstrated disease-modifying effects in a dose-dependent manner in a strep cell wall-induced arthritis model of rheumatoid arthritis in rats.

Product Details of C4H11NO, 2-Methoxy-N-methylethanamine is a useful research compound. Its molecular formula is C4H11NO and its molecular weight is 89.14 g/mol. The purity is usually 95%.
2-Methoxy-N-methylethanamine is a drug that binds to the cannabinoid receptor CB1. It has been shown to be effective in the treatment of cardiac arrhythmia and may also be used as an anti-inflammatory drug. 2MEMEA has been shown to have pharmacokinetic properties that are different from those of other amines, which may be due to its ability to form hydrogen bonds with water molecules. 2MEMEA also has diversified effects on some types of cancer cells, including hyperproliferative and amine-dependent cancers., 38256-93-8.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers lack the hydroxyl groups of alcohols. Without the strongly polarized O―H bond, ether molecules cannot engage in hydrogen bonding with each other. 38256-93-8, formula is C4H11NO, Name is 2-Methoxy-N-methylethanamine. Ethers do have nonbonding electron pairs on their oxygen atoms, however, and they can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. Recommanded Product: 2-Methoxy-N-methylethanamine.

Isa, Kazuki;Minakawa, Maki;Kawatsura, Motoi research published 《 Palladium-catalyzed amination of 2,3,3-trifluoroallyl esters: synthesis of trifluoromethylenamines via an intramolecular fluorine shift and CF₃ group construction》, the research content is summarized as follows. The palladium-catalyzed reaction of 2,3,3-trifluoroallyl esters with several types of amines afforded trifluoromethylenamines, e.g. I, which were formed by the addition of a nitrogen nucleophile at the C-2 position and the intramol. construction of the trifluoromethyl group via the fluorine atom shift from the C-2 to the C-3 position.

Recommanded Product: 2-Methoxy-N-methylethanamine, 2-Methoxy-N-methylethanamine is a useful research compound. Its molecular formula is C4H11NO and its molecular weight is 89.14 g/mol. The purity is usually 95%.
2-Methoxy-N-methylethanamine is a drug that binds to the cannabinoid receptor CB1. It has been shown to be effective in the treatment of cardiac arrhythmia and may also be used as an anti-inflammatory drug. 2MEMEA has been shown to have pharmacokinetic properties that are different from those of other amines, which may be due to its ability to form hydrogen bonds with water molecules. 2MEMEA also has diversified effects on some types of cancer cells, including hyperproliferative and amine-dependent cancers., 38256-93-8.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem