Category: 33797-34-1

Formula: C9H12O2On March 28, 1979, Kende, Andrew S.; Curran, Dennis P. published an article in Journal of the American Chemical Society. The article was 《Regiochemical control in dihydrophenanthrene synthesis. A photochemical total synthesis of juncusol》. The article mentions the following:

Three approaches are described toward the total synthesis of juncusol (I), a cytotoxic constituent of the needlerush Juncus roemerianus. Wittig condensation of the phosphonium salt derived from 2-methyl-3-methoxybenzyl bromide with 3-methoxy-4-methyl-5-cyanobenzaldehyde gave a mixture of cyanostilbenes, (E)- and (Z)-2,3-Me(MeO)C6H3CH:CHC6H2(CN)(OMe)Me-3,5,4. Reduction of this mixture gave the diarylethane, which failed to undergo oxidative aryl-aryl cyclization. Photocyclization of the stilbenes gave a 7:1 mixture of phenanthrenes in which the unwanted 7-cyano regioisomer predominated. The Ziegler modification of the Ullmann coupling was used to prepare the sym. dialdehyde II, which underwent successive Wittig reaction with Ph3P:CH2 and hydride reduction to give the key intermediate III. Photocyclization of III gave a dihydrophenanthrene alc. which underwent successive oxidation to an aldehyde, Wittig condensation with Ph3P:CH2, and demethylation to give I. The overall yield of I from 2-methyl-3-methoxybenzaldehyde is 18% over 10 steps; the route provides the first total synthesis of this natural product. The experimental part of the paper was very detailed, including the reaction process of (3-Methoxy-2-methylphenyl)methanol(cas: 33797-34-1Formula: C9H12O2)

(3-Methoxy-2-methylphenyl)methanol(cas: 33797-34-1) belongs to ethers. Ethers lack the hydroxyl groups of alcohols. Formula: C9H12O2 Without the strongly polarized O―H bond, ether molecules cannot engage in hydrogen bonding with each other.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 1973,Bulletin de la Societe Chimique de France included an article by Moreau, Claude; Rouessac, Francis. Recommanded Product: 33797-34-1. The article was titled 《Thermal behavior of three alkenylphenols. 5-m- and -p-hydroxyphenyl-1-pentene and o-methyl-5-m-hydroxyphenyl-1-pentene. I》. The information in the text is summarized as follows:

The thermal cyclization of pentenylphenols R(CH2)3CH:CH2 (I, R = hydroxyphenyl) was studied. I (R = m-HOC6H4) gave two naphthol derivatives in the liquid phase and one naphthol derivative in the gas phase, while I (R = p-HOC6H4) did not cyclize. A naphthol derivative was formed, in the liquid phase, from I [R = 2,3-Me(HO)C6H3]. The experimental part of the paper was very detailed, including the reaction process of (3-Methoxy-2-methylphenyl)methanol(cas: 33797-34-1Recommanded Product: 33797-34-1)

(3-Methoxy-2-methylphenyl)methanol(cas: 33797-34-1) belongs to ethers. Ethers lack the hydroxyl groups of alcohols. Without the strongly polarized O―H bond, ether molecules cannot engage in hydrogen bonding with each other. Recommanded Product: 33797-34-1

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《Hydrazide-Catalyzed Polyene Cyclization: Asymmetric Organocatalytic Synthesis of cis-Decalins》 was published in Angewandte Chemie, International Edition in 2020. These research results belong to Plamondon, Samuel J.; Warnica, Josephine M.; Kaldre, Dainis; Gleason, James L.. Quality Control of (3-Methoxy-2-methylphenyl)methanol The article mentions the following:

Polyene cyclizations offer rapid entry into terpenoid ring systems. Although enantioselective cyclizations of (E)-polyenes to form trans-decalin ring systems are well precedented, highly enantioselective cyclizations of (Z)-polyenes to form the corresponding cis-decalins have not been reported. Here, we describe the first application of iminium catalysis to the initiation of polyene cyclizations. Et 1,2-diazepane-1-carboxylate catalyzes the cyclization of polyenes bearing enal initiators. Moreover, chiral bicyclic hydrazides catalyze the cyclizations of (Z)-polyene substrates to form cis-decalins with enantioselectivities of up to 97:3 er. DFT calculations suggest the catalysts promote the reaction by stabilizing pos. charge as it develops during the bicyclization.(3-Methoxy-2-methylphenyl)methanol(cas: 33797-34-1Quality Control of (3-Methoxy-2-methylphenyl)methanol) was used in this study.

(3-Methoxy-2-methylphenyl)methanol(cas: 33797-34-1) belongs to ethers.Oxygen is more electronegative than carbon, thus the alpha hydrogens of ethers are more acidic than those of simple hydrocarbons. Quality Control of (3-Methoxy-2-methylphenyl)methanol They are far less acidic than alpha hydrogens of carbonyl groups (such as in ketones or aldehydes), however.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

SDS of cas: 33797-34-1On March 31, 2018, Manuri, Brahmayya; Dasi, Samsonu; Korla, Praveen Kumar published an article in Proceedings of the National Academy of Sciences, India, Section A: Physical Sciences. The article was 《Neat Synthesis of Substituted Benzoic Acids Employing TBHP/Oxone Catalyst and Study of Their Anti-oxidant Activity》. The article mentions the following:

In the present study, a variety of benzyl alcs. are synthesized from corresponding benzoic acids employing TBHP/oxone and FeCl3 as an effective and selective catalyst under solvent free conditions. The conversion rate and yields of the products are significant. The advantages of the selected catalyst are: cheaply available and more selectivity of the product formations rather than the formation of any undesired byproducts. The synthesized compounds were tested for anti-oxidant activities. In the experiment, the researchers used (3-Methoxy-2-methylphenyl)methanol(cas: 33797-34-1SDS of cas: 33797-34-1)

(3-Methoxy-2-methylphenyl)methanol(cas: 33797-34-1) belongs to ethers.SDS of cas: 33797-34-1Although ethers resist hydrolysis, they are cleaved by hydrobromic acid and hydroiodic acid. Hydrogen chloride cleaves ethers only slowly.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem