Category: 321-28-8

On January 31, 2015, He, Nana; Wu, Xiaoqin; Guo, Xianghai; Bai, Peng published an article.Product Details of 321-28-8 The title of the article was ortho-fluoroanisole: A new donor for boron isotopes separation by chemical exchange distillation. And the article contained the following:

10B is an effective neutron absorbent, which endows its duty in nuclear industry as a protecting agent. The only industrialized process for preparation of 10B is chem. exchange distillation using anisole as a complexing agent. The drawbacks such as low isotope separation factor and instability under process conditions inspired continuous interests to find a replacement. A new complexing agent, o-fluoroanisole, was selected and evaluated for boron isotopes separation O-fluoroanisole demonstrates better properties such as higher separation factor, lower f.p. of the complex and longer cycle life compared with those of anisole, which suggest it as a noteworthy agent used for separating isotopes. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).Product Details of 321-28-8

The Article related to ortho fluoroanisole donor boron isotope separation chem exchange distillation, Nuclear Technology: Isotopes and Isotopic Radiation Sources and other aspects.Product Details of 321-28-8

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Ether – Wikipedia,
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On November 5, 2021, Neil, Baptiste; Lucien, Franck; Fensterbank, Louis; Chauvier, Clement published an article.Product Details of 321-28-8 The title of the article was Transition-Metal-Free Silylation of Unactivated C(sp2)-H Bonds with tert-Butyl-Substituted Silyldiazenes. And the article contained the following:

Aromatic organosilanes bearing C(sp2)-Si bonds found increasing applications across the chem. science, yet are mostly produced by atom-uneconomical stoichiometric procedures. Catalytic alternatives using hydrosilanes as Si sources also were described, but they display unfavorable thermodn. and are mostly based on expensive catalytic systems, often derived from noble metals, or lack generality. Herein, the authors describe the use of an alternative Si source, the tert-butyl-substituted silyldiazenes (tBu-N:N-SiR3), that are readily accessible from com. available precursors and whose structure enables the C(sp2)-H bond silylation of unactivated heteroaryl and aryl compounds under ambient, transition-metal-free catalytic conditions. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).Product Details of 321-28-8

The Article related to unactivated carbon hydrogen bond heteroaryl aromatic compound silylation silyldiazene, aromatic organosilane preparation, heteroaryl silane preparation, Organometallic and Organometalloidal Compounds: Silicon Compounds and other aspects.Product Details of 321-28-8

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Ether – Wikipedia,
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On February 10, 2022, Lee, Hiu-Fung; Lacbay, Cyrus M.; Boutin, Rebecca; Matralis, Alexios N.; Park, Jaeok; Waller, Daniel D.; Guan, Tian Lai; Sebag, Michael; Tsantrizos, Youla S. published an article.Safety of 1-Fluoro-2-methoxybenzene The title of the article was Synthesis and Evaluation of Structurally Diverse C-2-Substituted Thienopyrimidine-Based Inhibitors of the Human Geranylgeranyl Pyrophosphate Synthase. And the article contained the following:

Novel analogs of C-2-substituted thienopyrimidine-based bisphosphonates (C2-ThP-BPs) are described that are potent inhibitors of the human geranylgeranyl pyrophosphate synthase (hGGPPS). Members of this class of compounds induce target-selective apoptosis of multiple myeloma (MM) cells and exhibit antimyeloma activity in vivo. A key structural element of these inhibitors is a linker moiety that connects their (((2-phenylthieno[2,3-d]pyrimidin-4-yl)amino)methylene)bisphosphonic acid core to various side chains. The structural diversity of this linker moiety, as well as the side chains attached to it, was investigated and found to significantly impact the toxicity of these compounds in MM cells. The most potent inhibitor CML-07-119(13c)(I) was evaluated in mouse and rat for liver toxicity and systemic exposure, resp., providing further optimism for the potential value of such compounds as human therapeutics. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).Safety of 1-Fluoro-2-methoxybenzene

The Article related to multiple myeloma antimyeloma liver toxicity thienopyrimidine hggpps inhibitor pharmacokinetics, Pharmacology: Effects Of Neoplasm Inhibitors and Cytotoxic Agents and other aspects.Safety of 1-Fluoro-2-methoxybenzene

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Ether – Wikipedia,
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Chen, Zhenchun; Mei, Xin; Jin, Yuxia; Kim, Eun-Hye; Yang, Ziyin; Tu, Youying published an article in 2014, the title of the article was Optimisation of supercritical carbon dioxide extraction of essential oil of flowers of tea (Camellia sinensis L.) plants and its antioxidative activity.Formula: C7H7FO And the article contains the following content:

BACKGROUNDTo extract natural volatile compounds from tea (Camellia sinensis) flowers without thermal degradation and residue of organic solvents, supercritical fluid extraction (SFE) using carbon dioxide was employed to prepare essential oil of tea flowers in the present study. Four important parameters-pressure, temperature, static extraction time, and dynamic extraction time-were selected as independent variables in the SFE. RESULTSThe optimum extraction conditions were the pressure of 30 MPa, temperature of 50°C, static time of 10 min, and dynamic time of 90 min. Based on gas chromatog.-mass spectrometry anal., 59 compounds, including alkanes (45.4%), esters (10.5%), ketones (7.1%), aldehydes (3.7%), terpenes (3.7%), acids (2.1%), alcs. (1.6%), ethers (1.3%) and others (10.3%) were identified in the essential oil of tea flowers. Moreover, the essential oil of tea flowers showed relatively stronger DPPH radical scavenging activity than essential oils of geranium and peppermint, although its antioxidative activity was weaker than those of essential oil of clove, ascorbic acid, tert-butylhydroquinone, and butylated hydroxyanisole. CONCLUSIONEssential oil of tea flowers using SFE contained many types of volatile compounds and showed considerable DPPH scavenging activity. The information will contribute to the future application of tea flowers as raw materials in health-care food and food flavor industries. © 2013 Society of Chem. Industry. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).Formula: C7H7FO

The Article related to camellia essential oil supercritical carbon dioxide extraction, antioxidative activity, essential oil, supercritical carbon dioxide extraction, tea flower, volatile, Food and Feed Chemistry: Packaging, Preservation, and Processing and other aspects.Formula: C7H7FO

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On May 21, 2021, Kuleshova, Olena; Asako, Sobi; Ilies, Laurean published an article.Computed Properties of 321-28-8 The title of the article was Ligand-Enabled, Iridium-Catalyzed ortho-Borylation of Fluoroarenes. And the article contained the following:

A terpyridine derivative and an iridium complex catalyze the C-H borylation of a stoichiometric amount of a fluoroarene with high ortho-selectivity and tolerance of functional groups such as bromide, chloride, ester, ketone, amine, and in situ-borylated hydroxyl. Complex drug mols. such as haloperidol can be selectively borylated ortho to the F atom. The terpyridine ligand undergoes rollover cyclometalation to produce an N,N,C-coordinated iridium complex, which may either selectively borylate the fluoroarene by itself or undergo reductive elimination to produce a borylated ligand. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).Computed Properties of 321-28-8

The Article related to fluoroarene directed ortho borylation iridium catalyst preparation arylboronic ester, terpyridine iridium complex catalyst directed ortho borylation aryl fluoride, Organometallic and Organometalloidal Compounds: Boron Compounds and other aspects.Computed Properties of 321-28-8

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Ether – Wikipedia,
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On March 30, 2020, Zhang, Xiongfei; Zeng, Piaopiao; Zhang, Shuo; Chen, Zhiwei published an article.Related Products of 321-28-8 The title of the article was FeCl3-Mediated Friedel-Crafts Alkylation and Oxidative Annulations: Facile Synthesis of Benzofurans. And the article contained the following:

An efficient method for the facile synthesis of benzofurans through FeCl3-mediated intermol. tandem reaction of anisole with glyoxal monohydrates was reported. This process provided the privileged structures of benzofurans in moderate to good yields under mild conditions. This reaction has many advantages, such as readily available starting materials, high atom economy and good functional group tolerance. This is firstly reported that FeCl3, acting as both a Lewis acid and an oxidant, was used for the synthesis of benzofuran. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).Related Products of 321-28-8

The Article related to benzofuran preparation iron catalyst, anisole glyoxal monohydrate friedel crafts alkylation oxidative annulation, Heterocyclic Compounds (One Hetero Atom): Areno- and Diarenofurans and other aspects.Related Products of 321-28-8

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On August 6, 2021, Sukowski, Verena; Jia, Wen-Liang; van Diest, Rianne; van Borselen, Manuela; Fernandez-Ibanez, M. Angeles published an article.SDS of cas: 321-28-8 The title of the article was S,O-Ligand-Promoted Pd-Catalyzed C-H Olefination of Anisole Derivatives. And the article contained the following:

The C-H olefination of substituted anisole derivatives by a Pd/S,O-ligand catalyst is reported. The reaction proceeds under mild conditions with a broad range of substituted aryl ethers bearing both electron donating and withdrawing substituents at ortho, meta and para positions. Aryl ethers are used as limiting reagents and good yields and site selectivities are observed The methodol. is operationally simple and can be performed under aerobic conditions. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).SDS of cas: 321-28-8

The Article related to anisole olefination palladium catalyst, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: General and other aspects.SDS of cas: 321-28-8

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Ether – Wikipedia,
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On June 30, 2014, Wu, Xiaoqin; Bai, Peng; Guo, Xianghai; He, Nana published an article.Quality Control of 1-Fluoro-2-methoxybenzene The title of the article was 2,4-Difluoroanisole: a promising complexing agent for boron isotopes separation by chemical exchange reaction and distillation. And the article contained the following:

Although methods of boron isotopes separation were intensively pursued about 60 years, the chem. exchange distillation is the only method that has been applied in industrial scale production of 10B. The present anisole BF3 system suffers from the drawbacks like high m.p., relatively low separation coefficient and instability under reaction conditions, which demand a continuous search for more effective and efficient donors for boron isotope separation A series of fluoro-substituted anisole derivatives were screened in this paper, among which 2,4-difluoroanisole exhibited good properties compared with anisole. Studies on the boron trifluoride and 2,4-difluoroanisole adduct, its thermodn. and phys. properties related to large-scale isotopic separation is reported. The results showed that 2,4-difluoroanisole is better than anisole in separation coefficient, f.p. and stability under pyrolysis conditions, which suggest a further detailed investigations on boron trifluoride and 2,4-difluoroanisole adduct. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).Quality Control of 1-Fluoro-2-methoxybenzene

The Article related to fluoroanisole complexing agent boron isotope separation chem exchange distillation, Physical Organic Chemistry: Other Reactions, Processes, and Spectra and other aspects.Quality Control of 1-Fluoro-2-methoxybenzene

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Ether – Wikipedia,
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On March 15, 2021, Aniceto, Jose P. S.; Zezere, Bruno; Silva, Carlos M. published an article.Related Products of 321-28-8 The title of the article was Machine learning models for the prediction of diffusivities in supercritical CO2 systems. And the article contained the following:

The mol. diffusion coefficient is fundamental to estimate dispersion coefficients, convective mass transfer coefficients, etc. Since exptl. diffusion data is scarce, there is significant demand for accurate models capable of providing reliable diffusion coefficient estimations In this work we applied machine learning algorithms to develop predictive models to estimate diffusivities of solutes in supercritical carbon dioxide. A database of exptl. data containing 13 properties for 174 binary systems totaling 4917 data points was used in the training of the models. Five machine learning algorithms were evaluated and the results were compared with three commonly used classic models. The best results were found using the Gradient Boosted algorithm which showed an average absolute relative deviation (AARD) of 2.58% (pure prediction). This model has five parameters: temperature, d., solute molar mass, solute critical pressure and solute acentric factor. For the same dataset, the classic Wilke-Chang equation showed AARD of 12.41%. The developed model is provided as command line program. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).Related Products of 321-28-8

The Article related to carbon dioxide supercritical system machine learning diffusivity, Phase Equilibriums, Chemical Equilibriums, and Solutions: Fused Salts and other aspects.Related Products of 321-28-8

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Alhamed, Samiyah; Alnakhli, Jawzah; Boadi, William; Beni, Ryan published an article in 2019, the title of the article was Triphenylmethanol conjugates of triptorelin as anti-lipid peroxidation prodrugs.Product Details of 321-28-8 And the article contains the following content:

Antioxidants are substances that can prevent or slow damage to cells caused by free radicals, unstable mols. that the body produces as a reaction to environmental and other pressures. Free radicals may play a role in heart disease, cancer and other diseases. If the body cannot process and remove free radicals efficiently, oxidative stress can result. This can harm cells and body function. Free radicals are also known as reactive oxygen species (ROS). In this research, Triptorelin (TRP) conjugates of triphenylmethanol derivatives (TPMs) were synthesized to evaluate their in vitro lipid peroxidation potency. Comparative lipid peroxidation assays between TRP-TPMs conjugates and the corresponding TPMs derivatives were measured using thiobarbituric reactive substance (TBARS) in a dose- and time-dependent manner following the Fenton’s pathway. Overall, TBARS decreased between 20% – 30% for the treated samples of synthesized conjugates compared to their resp. control phys. mixtures These data suggest that TRP-TPMs derivatives can be used to improve the biol. activity of TRP. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).Product Details of 321-28-8

The Article related to triphenylmethanol triptorelin antilipid peroxidation, Pharmacology: Other (All Agents and Effects Not Otherwise Assignable) and other aspects.Product Details of 321-28-8

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Ether – Wikipedia,
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