Category: 2944-47-0

Nilsson, Aake published the artcileStructural effects on selective aliphatic hydrogen exchange in alkyl-substituted aromatic compounds in deuterated trifluoroacetic acid, Category: ethers-buliding-blocks, the publication is Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry (1985), B39(1), 25-30, database is CAplus.

A qual. study was carried out concerning structural effects on selective aliphatic H exchange for a variety of alkylated aromatic compounds in CF₃CO₂D. β-H exchange in iso-Pr and cyclohexyl groups is severely hindered by the presence of an ortho substituent, whereas this is not the case for the exchange in a cyclopentyl group. In 1-isopropylnaphthalene (1-I), hindrance from the peri H inhibits aliphatic H exchange in the Me group, whereas aliphatic exchange does occur in 2-I. Also, bulky substituents [e.g., iso-Pr groups ortho to the MeO group in 2,4,6-(Me₂CH)₃C₆H₂OMe] retard the rate of H exchange in the 4-iso-Pr group strongly. Structural effects on aliphatic β-H exchange for some derivatives of indan, Tetralin, chroman, Ph₂O and biphenyl were also studied. For the indan and Tetralin derivatives, the presence of a methine H in the benzylic position was no longer necessary for aliphatic H exchange to occur. For 5-methoxy-1-methylindan, α-H exchange in position 1 was also observed along with the β-H exchange.

Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, Category: ethers-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Gowrisankar, Saravanan published the artcileA convenient and practical synthesis of anisoles and deuterated anisoles by palladium-catalyzed coupling reactions of aryl bromides and chlorides, Product Details of C10H14O, the publication is Chemistry – A European Journal (2012), 18(9), 2498-2502, S2498/1-S2498/31, database is CAplus and MEDLINE.

A palladium-catalyzed coupling reaction of aryl halides with methanol is described. A variety of substituted anisoles have been prepared in moderate to good yields from activated and nonactivated (hetero)aryl substrates. Meanwhile, deuterated anisoles could be obtained via coupling of aryl halides with CD₃OD.

Chemistry – A European Journal published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, Product Details of C10H14O.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Yoshimura, Hiroyuki published the artcileA Novel Type of Retinoic Acid Receptor Antagonist: Synthesis and Structure-Activity Relationships of Heterocyclic Ring-Containing Benzoic Acid Derivatives, Application In Synthesis of 2944-47-0, the publication is Journal of Medicinal Chemistry (1995), 38(16), 3163-73, database is CAplus and MEDLINE.

A new series of heterocyclic ring-containing benzoic acids was prepared, and the binding affinity and antagonism of its members against all-trans-retinoic acid were evaluated by in vitro assay systems using human promyelocytic leukemia (HL-60) cells. Structure-activity relationships indicated that both an N-substituted pyrrole or pyrazole (1-position) and a hydrophobic region, with these linked by a ring system, were indispensable for effective antagonism. Among the compounds evaluated, optimal antagonism was exhibited by 4-[4,5,7,8,9,10-hexahydro-7,7,10,10-tetramethyl-1-(3-pyridylmethyl)anthra[1,2-b]pyrrol-3-yl]benzoic acid, 4-[7,8,9,10-tetrahydro-7,7,10,10-tetramethyl-1-(3-pyridylmethyl)-4-thiaanthra[1,2-b]pyrrol-3-yl]benzoic acid, and 4-[4,5,7,8,9,10-hexahydro-7,7,10,10-tetramethyl-1-(3-pyridylmethyl)anthra[2,1-d]pyrazol-3-yl]benzoic acid, all of which possess a 3-pyridylmethyl group at the five-membered ring nitrogen atom.

Journal of Medicinal Chemistry published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C2H10Cl2N2, Application In Synthesis of 2944-47-0.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Buchanan, Gerald W. published the artcileCarbon-13 nuclear magnetic resonance studies of ortho-substituted anisoles and diphenyl ethers, Quality Control of 2944-47-0, the publication is Canadian Journal of Chemistry (1974), 52(5), 767-74, database is CAplus.

Carbon-13 NMR chem. shifts for 8 anisoles and 15 diphenyl ethers are reported. para-Carbon shieldings are sensitive to the degree of steric interference to conjugative electron release by the ethereal O atom. An empirical correlation between the para-carbon shifts and the average twist angle of the Ph rings from a reference plane was developed. Satisfactory agreement was found between the angles of twist derived from C-13 chem. shifts and those based on other phys. measurements.

Canadian Journal of Chemistry published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, Quality Control of 2944-47-0.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Shimizu, Ken-ichi published the artcileSilica-Supported Silver Nanoparticles with Surface Oxygen Species as a Reusable Catalyst for Alkylation of Arenes, COA of Formula: C10H14O, the publication is ChemCatChem (2010), 2(1), 84-91, database is CAplus.

A series of silica-supported silver catalysts with various Ag loading (3-30 wt %) and different treatment (oxidation and subsequent reduction by H₂) were prepared, and their local structures were characterized by extended x-ray absorption fine structure (EXAFS) anal. In oxidized catalysts, silver were mainly present as small nanoparticles with surface oxygen atoms, and the number of surface oxygen atoms decreased with increased silver loading. The H₂ reduction of these samples resulted in a removal of the surface oxygen atoms. The structure-activity relationship was studied for the alkylation of anisole with benzyl alc. and styrene. Ag^I oxide, Ag^I ion, bulk silver metal, and silica-supported silver nanoparticles were non-active species. In contrast, silica-supported silver nanoparticles with the surface oxygen atoms acted as an effective heterogeneous catalyst for the alkylation of arenes with alcs. and styrenes. Kinetic studies in alkylation of anisole with alcs. showed that the cleavage of the α-C-H bond of alc. was the rate-limiting step. It is proposed that the surface oxygen adjacent to the silver surface atoms plays an important role in the dissociation of the α-C-H bond.

ChemCatChem published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C9H9NO6S, COA of Formula: C10H14O.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Metcalf, Robert L. published the artcileEvolution of olfactory receptor in oriental fruit fly Dacus dorsalis, Application In Synthesis of 2944-47-0, the publication is Proceedings of the National Academy of Sciences of the United States of America (1979), 76(4), 1561-5, database is CAplus and MEDLINE.

Male D. dorsalis from colonies in Taiwan and Hawaii were evaluated for their limit of response to various analogs of methyleugenol. The results are interpreted in terms of the geometry and allosteric requirements of the antennal receptor that triggers the characteristic methyleugenol reflex. This receptor has evolved for complementarity to all portions of the methyleugenol mol. and responds only to ortho-substituted benzenes with adjacent atoms or isoelectronic equivalents Substantial differences in responses of Taiwan and Hawaiian D. dorsalis suggest that perceptible evolution of the receptor protein has occurred during the past 50 yr. A plausible scheme for the coevolution of flies with plants containing phenylpropionoid essential oils is outlined.

Proceedings of the National Academy of Sciences of the United States of America published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, Application In Synthesis of 2944-47-0.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Barluenga, J. published the artcileFriedel-Crafts reactions of beta-substituted organomercury(II) compounds, Safety of 2-Isopropylanisole, the publication is Anales de Quimica (1968-1979) (1977), 73(7-8), 1032-4, database is CAplus.

Alkylation of aromatic rings (e.g. in PhOMe) with β-oxymercuric compounds (e.g. AcOCHMeCH₂HgBr) in the presence of a Lewis acid (e.g. AlCl₃) gave, besides alkylarom. compounds (e.g. o-MeOC₆H₄CHMe₂), β-functionalized alkylarom. compounds (e.g. o-MeOC₆H₄CH₂CHMe(OAc)].

Anales de Quimica (1968-1979) published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, Safety of 2-Isopropylanisole.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Dalla Cort, Antonella published the artcileInherently Chiral Uranyl-Salophen Macrocycles: Computer-Aided Design and Resolution, COA of Formula: C10H14O, the publication is Journal of Organic Chemistry (2005), 70(24), 9814-9821, database is CAplus and MEDLINE.

A flipping motion rapidly inverts the bent structure of uranyl-salophen compounds and, consequently, causes fast enantiomerization of nonsym. substituted derivatives This process was previously slowed by introducing bulky substituents in the imine bond region. Since the resulting complexes dissociate upon chromatog. treatment, an alternative approach to the design and synthesis of robust, nonflipping uranyl-salophen compounds is here described. Such an approach is based on the idea that the flipping motion would be blocked by connecting the para positions with respect to the phenoxide oxygens by polymethylene bridges of suitable length. Anal. of a number of uranyl-salophen compounds by mol. mechanics, while showing that bulky substituents in the imine bond region cause severe distortions of the ligand backbone, suggested that the best chain lengths are those that fit the gap between the phenoxide rings without altering the natural geometry of the parent uranyl-salophen compound Calculations showed that such chains are those composed of 12 and 13 methylene units. Accordingly, chiral uranyl-salophen macrocycles bridged with 12- and 13-methylene chains, [UO₂(L)] (H₂L = I, n = 1, 2; R = i-Pr, R’ = Ph), were synthesized in fairly good yields and resolved by chiral HPLC.

Journal of Organic Chemistry published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, COA of Formula: C10H14O.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Chen, Han published the artcileRelationship between volatile components of green pepper and its freshness, COA of Formula: C10H14O, the publication is Shipin Kexue (Beijing, China) (2016), 37(7), 66-71, database is CAplus.

Volatile components of green pepper stored in refrigerator at (4±1)°C for different periods were evaluated by head space solid-phase micro extraction-gas chromatog.-mass spectrometry (HS-SPME-GC-MS). Soluble solid content, weight loss ratio and vitamin C content and were analyzed to probe into the relationship of pepper freshness and its volatile components. The results showed that green pepper could be kept fresh at (4±1)°C for 15 days. The characteristic odor components of fresh green pepper were hexyl octanoate, (E,E)-2,4-decadienal and 3-octanone, whereas those of rotten green pepper were α-myrcene, α-phellandrene, (E)-α-famesene, 2-propenoic acid, 3-phenyl-Et ester, hexadecanoic acid, Et ester and n-decanoic acid with variation thresholds of 6.54, 13.47, 32.78, 7.74, 9.10 and 17.13 μg/L, resp. These results can provided a theor. basis for judging the freshness of pepper by changes of the volatile components and accordingly for developing smart refrigerator to monitor the freshness of green pepper.

Shipin Kexue (Beijing, China) published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, COA of Formula: C10H14O.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Amandi, Rodrigo published the artcileFriedel-Crafts Alkylation of Anisole in Supercritical Carbon Dioxide: A Comparative Study of Catalysts, Recommanded Product: 2-Isopropylanisole, the publication is Organic Process Research & Development (2005), 9(4), 451-456, database is CAplus.

The Friedel-Crafts alkylation of anisole with n-propanol was carried out over five different Bronsted solid acid catalysts using supercritical carbon dioxide as the reaction medium. The reaction temperature and pressure were evaluated in terms of selectivity for the monoalkylated products, conversion of the starting material, and the products’ isomeric ratio. Desulfonation of the catalysts was observed when the temperature was increased above 150 °C for the organic supported catalysts investigated Amberlyst 15 and Purolite CT-175, and above 200 to 250 °C for the inorganic supported catalysts Nafion SAC-13 and Deloxan ASP I/7. A decrease in the catalytic performance of organic supported catalysts was observed with increasing pressure. This decrease was related to the phase behavior of the reaction.

Organic Process Research & Development published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, Recommanded Product: 2-Isopropylanisole.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem