Category: 2944-47-0

Bruzik, K. published the artcileThiono-thiolo rearrangement and solvolysis of the secondary alkyl phosphorothionates. 3, Synthetic Route of 2944-47-0, the publication is Journal of Organic Chemistry (1981), 46(8), 1618-24, database is CAplus.

The protic acid-catalyzed thiono-thiolo (O→S) migration of secondary alkyl groups R in title esters I occurs in a complex fashion. Anal. of product distribution, stereochem., and D-incorporation experiments supports an ion pair-type intermediate (e.g., II.CF₃CO₂^–R⁺) as being responsible for the entire process. Nucleophilic attack by I on the ion pair initiates the chain reaction leading to III. In CF₃CO₂H, inversion of configuration (96%) at the C atom of the migrating EtCHMe group was observed A high concentration of I promotes this mode of rearrangement. However, the overall stereospecificity of EtCHMe migration is much lower, owing to an elimination process leading to the dialkyl H phosphorothioate II and an intermediate olefin which after protonation in acidic medium returns to the ion pair. The latter process is responsible for the nonstereospecific formation of part of the rearrangement product III and contributes to the lower stereospecificity of the trifluoroacetolysis process. The role of the acidity of the medium is discussed.

Journal of Organic Chemistry published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, Synthetic Route of 2944-47-0.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Amaro, Ana L. published the artcileMultitrait analysis of fresh-cut cantaloupe melon enables discrimination between storage times and temperatures and identifies potential markers for quality assessments, Application In Synthesis of 2944-47-0, the publication is Food Chemistry (2018), 222-231, database is CAplus and MEDLINE.

Fresh-cut cantaloupe melon is valued for its aroma but is highly perishable. Temperature of storage (typically 0-5 °C) is critical for maintaining fresh-cut melon quality, but often reaches 10 °C during transportation and in retail outlets. A comparison amongst 0, 5 and 10 °C storage temperatures for fresh-cut melon over 14 days reveals that storage at 0 °C is optimal for avoiding increases in microbial load and loss of vitamin C especially at later time points. However, higher temperatures maintain better the balance of esters (acetate vs. non-acetate) and phenolic content. The whole volatile organic compound (VOC) profile can be used to discriminate both time and temperature effects especially at earlier time points. Potential VOC markers for changes in vitamin C from day 0 to day 6 of storage (3-Me butane nitrile) and temperature (limonene) are identified through a multi-trait anal.

Food Chemistry published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, Application In Synthesis of 2944-47-0.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Wang, Qinghe published the artcileSynthesis of diaryliodonium tetrafluoroborates, Recommanded Product: 2-Isopropylanisole, the publication is Zhongguo Yaowu Huaxue Zazhi (2000), 10(4), 288-289, database is CAplus.

Two diaryliodonium tetrafluoroborates bis(3-isopropyl-4-methoxyphenyl)iodonium tetrafluoroborate and bis(4-methoxyphenyl)iodonium tetrafluoroborate were synthesized by iodination of 2-isopropylphenyl Me ether or methoxybenzene in acetic anhydride in the presence of HNO₃ and trifluoroacetic acid at -30° and salification with NaBF₄.

Zhongguo Yaowu Huaxue Zazhi published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C8H6ClN, Recommanded Product: 2-Isopropylanisole.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Burmaoglu, Serdar published the artcileSyntheses and evaluation of multicaulin and miltirone-like compounds as antituberculosis agents, Product Details of C10H14O, the publication is Journal of Enzyme Inhibition and Medicinal Chemistry (2017), 32(1), 878-884, database is CAplus and MEDLINE.

Four multicaulin and miltirone-like phenanthrene derivatives were synthesized and evaluated as antituberculosis agents. The crucial step of the synthesis was Pschorr coupling of 4-(3-isopropyl-4-methoxyphenyl)-2-(2-aminophenyl)ethane to give 2-isopropyl-3-methoxy-9,10-dihydrophenanthrene and 4-isopropyl-3-methoxy-9,10-dihydrophenanthrene. 2-Isopropyl-3-methoxy-9,10-dihydrophenanthrene was converted to multicaulin and miltirone-like phenanthrene derivatives by further reactions. The best antituberculosis activity was exhibited by 2-isopropylphenanthrene-3-ol.

Journal of Enzyme Inhibition and Medicinal Chemistry published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, Product Details of C10H14O.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Makowski, Philippe published the artcileChlorine borrowing: An efficient method for an easier use of alcohols as alkylation agents, Recommanded Product: 2-Isopropylanisole, the publication is Green Chemistry (2009), 11(1), 34-37, database is CAplus.

Chlorine functionalized tin dioxide nanoparticles proved able to partially convert alcs. into the corresponding chlorides, which act as alkylation agents with an increased electrophilicity, as evidenced on ether formation and Friedel-Crafts reactions.

Green Chemistry published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, Recommanded Product: 2-Isopropylanisole.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Bowie, John H. published the artcileSolvent effects in nuclear magnetic resonance spectroscopy. X. Solvent shifts induced by benzene in ortho-and meta-substituted methoxybenzenes, Product Details of C10H14O, the publication is Journal of the Chemical Society [Section] B: Physical Organic (1967), 535-40, database is CAplus.

Solvent shifts (Δ = δCCl4-δC6H6 ppm.) for the methoxyl protons of meta-substituted anisoles correlate with σm of the substituent, but for ortho-substituted anisoles a better correlation between Δ and the dipole moment is found. The effect of introducing a methoxyl group ortho to a substituent in a benzene ring is to make the Δ values for protons in that substituent more neg. In the compounds examined, protons α to the benzene ring (Ar-CH) and attached to a substituent situated between two o-methoxyl groups are only shielded (0.4-0.6 ppm.) in benzene relative to CCl4. On the basis of the observed shifts the orientating effect of an aromatic methoxyl function in a solute upon benzene solvent mols. may be surmised.

Journal of the Chemical Society [Section] B: Physical Organic published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, Product Details of C10H14O.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Tao, Zhonglin published the artcileEnantioselective, Lewis Base-Catalyzed Sulfenocyclization of Polyenes, Product Details of C10H14O, the publication is Journal of the American Chemical Society (2018), 140(10), 3569-3573, database is CAplus and MEDLINE.

A sulfenium-ion-initiated, catalytic, enantioselective polyene cyclization is described. Homogeranylarenes and ortho-geranylphenols undergo polycyclization in good yield, diastereoselectivity, and enantioselectivity. The stereodetermining step is the generation of an enantiomerically enriched thiiranium ion from a terminal alkene and a sulfenylating agent in the presence of a chiral Lewis basic catalyst. The use of hexafluoroisopropyl alc. as the solvent is crucial to obtain good yields. The thioether moiety resulting from the reaction can be subsequently transformed into diverse oxygen and carbon functionality postcyclization. The utility of this method is demonstrated by the enantioselective syntheses of (+)-ferruginol (I) and (+)-hinokiol (II).

Journal of the American Chemical Society published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C6H6N2O, Product Details of C10H14O.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Lorenc, Chris published the artcileAcid mediated deprotection of N-isopropyl tertiary amides, Application of 2-Isopropylanisole, the publication is Tetrahedron Letters (2015), 56(10), 1280-1282, database is CAplus.

Tertiary amides containing an N-iso-Pr group were selectively deprotected by heating in methanesulfonic acid. The N-iso-Pr group was removed selectively in the presence of other groups on the amide nitrogen such as Me, primary alkyl, or aryl. The putative iso-Pr cation was trapped by Friedel-Crafts alkylation of anisole when the latter was included as a co-solvent.

Tetrahedron Letters published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, Application of 2-Isopropylanisole.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Bhar, Shanta S. published the artcileAnnulation strategy for the biomimetic synthesis of cis-fused diterpenoids, Safety of 2-Isopropylanisole, the publication is Tetrahedron Letters (2006), 47(44), 7805-7807, database is CAplus.

Concise and efficient formal syntheses of the A/B cis-fused ring C-aromatic tricyclic diterpenes, xanthoperol, and cis-A/B-coleon V are reported, via the application of domino reactions followed by a novel annulation method, in which the highly substituted target mols. are assembled from an acyclic precursor, namely the easily accessible monoterpene, citral.

Tetrahedron Letters published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, Safety of 2-Isopropylanisole.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Liu, Luo-Yan published the artcilemeta C-H Arylation of Electron-Rich Arenes: Reversing the Conventional Site Selectivity, Recommanded Product: 2-Isopropylanisole, the publication is Journal of the American Chemical Society (2019), 141(37), 14870-14877, database is CAplus and MEDLINE.

Controlling site selectivity of C-H activation without using a directing group remains a significant challenge. While Pd(II) catalysts modulated by a mutually repulsive pyridine-type ligand have been shown to favor the relatively electron-rich carbon centers of arenes, reversing the selectivity to favor palladation at the relatively electron-deficient positions has not been possible. Herein we report the first catalytic system that effectively performs meta C-H arylation of a variety of alkoxy aromatics including 2,3-dihydrobenzofuran and chroman with exclusive meta site selectivity, thus reversing the conventional site selectivity governed by native electronic effects. The identification of an effective ligand and modified norbornene (NBE-CO₂Me), as well as taking advantage of the statistics, are essential for achieving the exclusive meta selectivity.

Journal of the American Chemical Society published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, Recommanded Product: 2-Isopropylanisole.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem