Category: 2944-47-0

Schuster, Ingeborg I. published the artcileA carbon-13 NMR study of the 1:1 hydrogen bond between trifluoroacetic acid and aromatic ethers in deuteriochloroform, HPLC of Formula: 2944-47-0, the publication is Journal of Organic Chemistry (1991), 56(2), 624-31, database is CAplus.

From the measured values of the equilibrium constants and ¹³C NMR shift changes for 1:1 hydrogen bonding of trifluoroacetic acid with 2-alkyl- and 2,6-dialkylanisoles and 7-alkyl-2,3-dihydrobenzofurans in deuteriochloroform, conclusions are drawn concerning the stereochemistries of the hydrogen bonded complexes. The data indicate that hydrogen bonding of the planar 2-alkylanisoles may involve rotation of the methoxy group about the aryl-OCH₃ bond, the rotational angles ranging from 13° (anisole) to 43° (tert-butylanisole). The values of log K₁ correlate roughly with the torsional potential for methoxy group rotation in anisole, recently obtained by means of quantum mechanics, and with the angle-dependent electron densities at the methoxy oxygens that have been calculated for these o-alkylanisoles. The equilibrium constants for hydrogen bonding of the 2,6-dialkylanisoles also follow the predicted order of increasing methoxy oxygen electronic charge. The results for the rotationally rigid 2,3-dihydrobenzofurans are compatible with preferential involvement of the oxygen sp² lone electron pair in hydrogen bond formation.

Journal of Organic Chemistry published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C15H14O, HPLC of Formula: 2944-47-0.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Demir, Hulya published the artcileEvaluation of the chemical profiling, total phenolic composition, the antioxidant and antimicrobial properties of the essential oils of Mentha piperita L., Salvia officinalis L., and Thymus vulgaris L, Application of 2-Isopropylanisole, the publication is Journal of Food Science and Engineering (2018), 8(6), 263-270, database is CAplus.

The purpose of this study was to determine the chem. composition, total phenolic composition, the antioxidant and antimicrobial properties of the essential oils (EOs) of Mentha piperita L., Salvia officinalis L., and Thymus vulgaris L. The essential oils of M. piperita L., S. officinalis L., and T. vulgaris L. were analyzed by means of gas chromatog.-mass spectrometry (GC-MS) to demonstrate their chem. composition The antioxidant properties of the EOs were evaluated with the 2,2-diphenyl-picrylhydrazyl (DDPH) free radical scavenging assay, their total phenolic compound contents were determined by the Folin Ciocalteau method, and their antimicrobial activities were evaluated by the disk diffusion assay. The major compounds in the contents of the essential oils of M. piperita L., S. officinalis L., and T. vulgaris L. were found to be eucalyptol, 1R-α-pinene, and o-cymene, resp. In the 2,2-diphenyl-picrylhydrazyl (DDPH) assay, the EO of M. piperita L. (8,930.01 μMTE/g) demonstrated the highest antioxidant activity, followed by the activities of the EOs of T. vulgaris L. (157.76 μMTE/g) and S. officinalis L. (115.54 μMTE/g). The total phenolic compound contents of M. piperita L., T. vulgaris L., and S. officinalis L. were measured as 135.074, 0.242, and 0.221 mMGAE/g. All essential oils showed antioxidant activities and antimicrobial activities. The highest antimicrobial activity against S. aureus, A. nigeris, and C. albicans was determined in the EO of M. piperita L. within diameters of 42, 32, and 28 mm, resp. These properties of essential oils are used in the pharmaceutical and food industries. The essential oils are approved as official medications in many countries and take place in their pharmacopoeias.

Journal of Food Science and Engineering published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, Application of 2-Isopropylanisole.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Bolton, Roger published the artcileSulfuryl chloride as an electrophile. IV. Steric hindrance to activation by the methoxy-group, Category: ethers-buliding-blocks, the publication is Journal of the Chemical Society [Section] B: Physical Organic (1970), 1770-2, database is CAplus.

The rates of reactions of sulfuryl chloride with a number of aromatic ethers have been studied in chlorobenzene solution The additivity principle, which holds in a number of examples of this reactions, fails when 2 substituents are placed ortho to the methoxyl group in anisole. 2,3,4,6-Tetramethylanisole substitutes Cl at a similar rate to that of 3-methylanisole, its calculated rate coefficient being 2000 times the exptl. value. Neither increasing the size of the alkyl group attached to the O atom nor using only 1 ortho substituent brought about any detectable effect due to steric factors.

Journal of the Chemical Society [Section] B: Physical Organic published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, Category: ethers-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Baliah, V. published the artcileEvidence for steric enhancement of resonance in 2-alkylanisoles from ¹³C NMR T₁ relaxation times of methoxy-carbons and from atomic charges on methoxy-oxygens, Recommanded Product: 2-Isopropylanisole, the publication is Journal of the Indian Chemical Society (1993), 70(10), 841-2, database is CAplus.

The title study of MeOC₆H₄R-2 (R = H, alkyl) and MeOC₆H₃R¹R²-2,6 (R¹ = R² = alkyl) confirmed the steric enhancement of resonance in these compounds

Journal of the Indian Chemical Society published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, Recommanded Product: 2-Isopropylanisole.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Zhang, Dejin published the artcileAn efficient method to prepare aryl acetates by the carbonylation of aryl methyl ethers or phenols, COA of Formula: C10H14O, the publication is New Journal of Chemistry (2021), 45(5), 2683-2687, database is CAplus.

A method of preparing aryl acetates ROC(O)CH₃ (R = Ph, 2-(propan-2-yl)phenyl, 4-fluorophenyl, 2,3,5-trimethylphenyl, etc.) by the carbonylation of aryl Me ethers ROCH₃ or phenols ROH under low CO pressure was developed. Good to excellent yields of aryl acetates were obtained using different substrates, and a possible reaction mechanism was proposed by conducting a series of control experiments This method may provide a potential way for the utilization of lignin.

New Journal of Chemistry published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H2F12NiO4, COA of Formula: C10H14O.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Wang, Zhifan published the artcileC(sp³)-H 1,3-diamination of cumene derivatives catalyzed by a dirhodium(II) catalyst, Application of 2-Isopropylanisole, the publication is Organic Chemistry Frontiers (2022), 9(12), 3274-3280, database is CAplus.

The simultaneous and direct amination of multiple inert Csp³-H bonds is a challenging method for C-N bond formation. Here, a radical sequential reaction mediated by a dirhodium(II) catalyst was developed for the successful one-step synthesis of 1,3-diamines via the interaction of cumene derivatives with N-fluorobenzenesulfonimide (NFSI). Mechanistic studies revealed that the reaction underwent an iterative radical polar crossover and desaturation activation procedure to achieve the activation of three adjacent C-H bonds. The synthesized diamine compounds were converted into useful functional mols. by further removal of phenylsulfonyl groups.

Organic Chemistry Frontiers published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C18H23N3O4S, Application of 2-Isopropylanisole.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Kinoshita, Hidenori published the artcileDiisobutylaluminum hydride-promoted cyclization of silylated 1,3-dien-5-ynes: Application to total synthesis of a 20-norabietane derivative, Application of 2-Isopropylanisole, the publication is Tetrahedron Letters (2017), 58(16), 1607-1610, database is CAplus.

The diisobutylaluminum hydride (DIBAL-H)-promoted benzocyclization, recently developed by this group, was adopted for the synthesis of a natural product containing a 9,10-dihydrophenanthrene skeleton to demonstrate its synthetic utility. One of the extracts from the roots of Salvia hydrangea DC. ex Bentham (Lamiaceae), a 20-norabietane derivative (I), was selected as the target mol. The key step forming the 9,10-dihydrophenanthrene skeleton was achieved by the DIBAL-H-promoted cyclization of a silylated 1,3-dien-5-yne easily accessible from a substituted α-tetralone.

Tetrahedron Letters published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, Application of 2-Isopropylanisole.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Tang, Shouchu published the artcileApplication of a Domino Friedel-Crafts Acylation/Alkylation Reaction to the Formal Syntheses of (±)-Taiwaniaquinol B and (±)-Dichroanone, Recommanded Product: 2-Isopropylanisole, the publication is Organic Letters (2008), 10(9), 1855-1858, database is CAplus and MEDLINE.

An efficient acid-promoted domino Friedel-Crafts (FC) acylation/alkylation reaction has been developed for the construction of the core 6,5,6-ABC tricyclic skeleton (e.g. I) of taiwaniaquinoids. The formal total syntheses of diterpenoids (±)-taiwaniaquinol B and (±)-dichroanone based on this strategy have been achieved.

Organic Letters published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C38H74Cl2N2O4, Recommanded Product: 2-Isopropylanisole.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Zhang, Chenglu published the artcileTotal synthesis of 3-carbonyl-10-demethyl-12-methoxyabietane, Safety of 2-Isopropylanisole, the publication is Liaoning Shifan Daxue Xuebao, Ziran Kexueban (2011), 34(1), 71-73, database is CAplus.

Total synthesis of 3-carbonyl-10-demethyl-12-methoxyabietane was explored according to the strategy of AC->ABC. The 3-carbonyl-10-demethyl-12-methoxyabietane was synthesized from 2-isopropyl-1-methoxybenzene by bromination in the presence of the catalyst ammonium phosphomolybdate, the addition of ethylene oxide and further bromination. All intermediates and target product were confirmed by IR, ¹H NMR and MS. In conclusion, a simple high yield synthetic route has been developed and the target mol. was successfully synthesized.

Liaoning Shifan Daxue Xuebao, Ziran Kexueban published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C16H12O, Safety of 2-Isopropylanisole.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Mirk, Daniela published the artcileOxidative coupling of alkylated anisole derivatives using MoCl₅, COA of Formula: C10H14O, the publication is Synlett (2004), 1970-1974, database is CAplus.

Despite the Lewis acidic character of MoCl₅ it can be employed for the selective oxidative coupling reaction of alkylated anisole derivatives without transalkylation or de-tert-butylation of the substrates. The spatial demand close to the donor function seemed to be beneficial.

Synlett published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, COA of Formula: C10H14O.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem