Category: 2380-78-1

Reproductive parasitism by worker honey bees suppressed by queens through regulation of worker mandibular secretions was written by Mumoki, Fiona N.;Pirk, Christian W. W.;Yusuf, Abdullahi A.;Crewe, Robin M.. And the article was included in Scientific Reports in 2018.Synthetic Route of C9H12O3 The following contents are mentioned in the article:

Social cohesion in social insect colonies can be achieved through the use of chem. signals whose production is caste-specific and regulated by social contexts. In honey bees, queen mandibular gland pheromones (QMP) maintain reproductive dominance by inhibiting ovary activation and production of queen-like mandibular gland signals in workers. We investigated whether honey bee queens can control reproductively active workers of the intraspecific social parasite Apis mellifera capensis, parasitising A. m. scutellata host colonies. Our results show that the queen’s QMP suppresses ovarian activation and inhibits the production of QMP pheromone signals by the parasitic workers, achieved through differential expression of enzymes involved in the biosynthesis of these pheromones at two points in the biosynthetic pathway. This is the first report showing that honey bee queens can regulate reproduction in intraspecific social parasites and deepens our understanding of the mol. mechanisms involved in the regulation of worker reproduction in social insects. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Synthetic Route of C9H12O3).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Synthetic Route of C9H12O3

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Sensory descriptive and comprehensive GC-MS as suitable tools to characterize the effects of alternative procedures on wine aroma. Part II: BRS Rub́ea and BRS Cora was written by Bonatto Machado de Castilhos, Mauricio;Luiz Del Bianchi, Vanildo;Gomez-Alonso, Sergio;Garcia-Romero, Esteban;Hermosin-Gutierrez, Isidro. And the article was included in Food Chemistry in 2020.Product Details of 2380-78-1 The following contents are mentioned in the article:

The present manuscript assessed the volatile and sensory profiles of BRS Rub́ea and BRS Cora wines elaborated from traditional, grape pre-drying and submerged cap winemaking. The wines contained a higher concentration of acetates (257 mg L^-1 to 547 mg L^-1) and Et and Me esters (183 mg L^-1 to 456 mg L^-1) in comparison with Vitis vinifera wines. PCA was applied (explaining 68.43% of the total variance), and the higher concentration of Et decanoate and Et octanoate, di-Et succinate, hydroxylinalool, and 2-Ph ethanol was responsible for describing the BRS Rub́ea wines as fruity/foxy. They also presented an intense jam note, probably due to their higher concentration of syringol and guaiacol. BRS Cora wines exhibited a vegetal note, possibly due to their higher concentration of 1-hexanol and cis-3-hexenol. Wines from pre-dried grapes presented higher concentration of furfural, assuming a bitter/burned almond aroma. Alternative winemaking accounted for suitable changes in wine aroma, enhancing wine quality. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Product Details of 2380-78-1).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Product Details of 2380-78-1

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Ether | (C2H5)2O – PubChem

Directional and integrated conversion of whole components in biomass for levulinates and phenolics with biphasic system was written by Feng, Junfeng;Tong, Le;Ma, Changyue;Xu, Yangyang;Jiang, Jianchun;Yang, Zhongzhi;Pan, Hui. And the article was included in Bioresource Technology in 2020.COA of Formula: C9H12O3 The following contents are mentioned in the article:

Integrated conversion and stepwise extraction of whole components in biomass with biphasic system are introduced for producing chems.: levulinates and phenolics. When methanol/dimethoxymethane as biphasic solvent, 46.51% Me levulinate and 18.78% phenolics were obtained with a conversion of 80.59 wt% per 4 g rice straw under the mild reaction conditions. Levulinates were collected with a 87.5 wt% high purity of Me levulinate with stepwise precipitation and extraction from the cellulose and hemicellulose. The results of acid value, f.p., induction period, kinematic viscosity, and flash point supposed that the extracted Me levulinate could meet the requirements of fuel additives. Depolymerized lignin was consisted of many low-mol. phenolics. These results illustrated that the biphasic system can promote the conversion of cellulose and hemicellulose to the same product Me levulinate through different intermediate transition compounds, and the catalyst can contribute to directly cleave the glycosidic bonds, β-O-4, and 4-O-5 with adequate protons. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1COA of Formula: C9H12O3).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.COA of Formula: C9H12O3

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Ether | (C2H5)2O – PubChem

Influence of beta glucosidases from native yeast on the aroma of Muscat and Tannat wines was written by de Ovalle, Stefani;Brena, Beatriz;Gonzalez-Pombo, Paula. And the article was included in Food Chemistry in 2021.Application In Synthesis of 4-Hydroxy-3-methoxyphenethanol The following contents are mentioned in the article:

It is now well established that β-glucosidases (BGLs) from non-Saccharomyces yeasts are key enzymes that hydrolyze grape-derived aroma precursors enhancing the flavor of wines. This work reports on the specificity for wine glycosides and the impact on wine aroma, of three native yeast β-glucosidases. Volatile compounds were analyzed by gas-chromatog. and mass spectroscopy (GC-MS) and wine aroma was studied by sensory anal. Issatchenkia terricola β-glucosidase stood out from the other β-glucosidases studied. The I. terricola BGL showed remarkable specificity for norisoprenoid aglycons such as: 3-oxo-7, 8-dihydro-alpha-ionol, 3-oxo-α-ionol, vomifoliol. This different specificity was perceived in the sensory tests. The judges described pleasant fruity, sweet, honey and raisin notes in both Tannat and Muscat wines treated with I. terricola BGL. These results are particularly remarkable for Tannat wines, since there are few reports concerning the application of β-glucosidases to enhance its aroma of Tannat, and none with BGLs from native yeasts. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Application In Synthesis of 4-Hydroxy-3-methoxyphenethanol).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Application In Synthesis of 4-Hydroxy-3-methoxyphenethanol

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Ether | (C2H5)2O – PubChem

Effect of Spanish-style processing steps and inoculation with Lactobacillus pentosus starter culture on the volatile composition of cv. Manzanilla green olives was written by de Castro, Antonio;Sanchez, Antonio Higinio;Cortes-Delgado, Amparo;Lopez-Lopez, Antonio;Montano, Alfredo. And the article was included in Food Chemistry in 2019.Category: ethers-buliding-blocks The following contents are mentioned in the article:

The effects of the main steps of Spanish-style processing (alk. treatment and fermentation) on the volatile composition of cv. Manzanilla green olives were studied. Both spontaneous and controlled fermentations were considered. In the latter case, a Lactobacillus pentosus strain from green olive fermentation brine was used as starter culture. The volatile profile was determined by headspace solid-phase microextraction (HS-SPME) combined with gas chromatog.-mass spectrometry (GC-MS). Most of the volatile compounds detected in fresh olives decreased or were undetected after alk. treatment, while several compounds (mostly acetic acid, 2-methylbutanoic acid, and ethanol) were formed as a result of this treatment. Over 50 new volatile components, mostly esters and phenols, appeared as a result of fermentation The most outstanding finding was a considerable increase in 4-Et phenol (almost 100-fold increase) in inoculated olives compared to the uninoculated product. However, a sensory panel did not find significant differences in odor perception. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Category: ethers-buliding-blocks).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Category: ethers-buliding-blocks

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Methanolysis Fractionation and Catalytic Conversion of Poplar Wood toward Methyl Levulinate, Phenolics, and Glucose was written by Zhai, Qiaolong;Hse, Chung-yun;Long, Feng;Shupe, Todd F.;Wang, Fei;Jiang, Jianchun;Xu, Junming. And the article was included in Journal of Agricultural and Food Chemistry in 2019.Synthetic Route of C9H12O3 The following contents are mentioned in the article:

In the present study, methanolysis of poplar biomass was conducted for the selective transformation of hemicellulose and lignin, which leads to Me glycosides (mainly C5 glycosides) and lignin fragments in the liquefied products that can be separated according to their difference in hydrophilicity. The distribution of Me glycosides and delignification was dependent on the presence of acid catalysts and reaction temperatures The obtained lignin fraction was separated into solid lignin fragments and liquid lignin oil according to their mol. weight distribution. Subsequently, directional conversion of Me C5 glycosides into Me levulinate was performed with dimethoxymethane/methanol as the cosolvent. A yield of 12-30% of Me levulinate yield (based on the Me glycoside) was achieved under these conditions. The remaining cellulose-rich substrate showed enhanced susceptibility to enzymic hydrolysis, resulting in a yield of glucose of above 70%. Overall, the described strategy shows practical implications for the effective valorization of biomass. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Synthetic Route of C9H12O3).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Synthetic Route of C9H12O3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Glycosylated simple phenolic profiling of food tannins using high resolution mass spectrometry (Q-Orbitrap) was written by Barnaba, C.;Larcher, R.;Nardin, T.;Dellacassa, E.;Nicolini, G.. And the article was included in Food Chemistry in 2018.Computed Properties of C9H12O3 The following contents are mentioned in the article:

Tannins are polyphenolic compounds extensively present in plants and used by food industry as processing aids. Due to the heterogeneity of plant sources, actions involved in food processing and tannin com. costs can be different. In the last years different approaches aimed at correctly identifying the tannin botanical origin have been developed, in order to satisfy the industry’s request to verify product labels. This work aimed to define the glycosidic simple phenolic profile of a large selection of monovarietal com. tannins of different origin, using a high-resolution untargeted approach. Using accurate mass, isotopic pattern and MS/MS fragmentation, 167 precursors, 89 as monoglycosylated and 78 as diglycosylated derivatives were tentatively identified in tannins, validating the untargeted approach with 3 custom-synthesized glycosidic precursors. Almost all tannin botanical varieties were shown to be characterized by a specific glycosylated phenolic profile, providing possible tools for tannin classification in the case of glycosylphenol standard availability. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Computed Properties of C9H12O3).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Computed Properties of C9H12O3

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Effect of Solvent, Role of Formic Acid and Rh/C Catalyst for the Efficient Liquefaction of Lignin was written by Matsagar, Babasaheb M.;Wang, Zheng-Yen;Sakdaronnarong, Chularat;Chen, Season S.;Tsang, Daniel C. W.;Wu, Kevin C.-W.. And the article was included in ChemCatChem in 2019.Application of 2380-78-1 The following contents are mentioned in the article:

We demonstrate highly efficient liquefaction of alkali lignin with a very high yield of THF-soluble bio-oil (91.5 wt %) using formic acid (FA) and Rh/C catalyst under relatively mild reaction conditions (250 °C, 6 h) in EtOH-H₂O co-solvent system. The monomeric products are identified in which alkyl guaiacols accounts for the main proportion. The role of FA was not only used as a liquid-phase in-situ hydrogen source but also acts as organic acid which can catalyze the hydrolysis reaction of -C-O-C ether bonds of lignin. Moreover, in the present study, the role of Rh/C and FA is demonstrated for the liquefaction of lignin. The replacement of pure H₂ gas by the liquid-phase FA (hydrogen source) can effectively prevent the char formation. The utilization of Rh/C catalyst helps for the conversion of alkenyl guaiacols to alkyl guaiacols suggesting the hydrogenation of phenolic monomers and further cleavage by hydrogenation results in the formation of bio-oil with lower mol. weight (Mn=466 g mol^-1) as well as lower O/C ratio (0.26). This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Application of 2380-78-1).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Application of 2380-78-1

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Solid-phase synthesis of curcumin mimics and their anticancer activity against human pancreatic, prostate, and colorectal cancer cell lines was written by Romanucci, Valeria;Giordano, Maddalena;Pagano, Rita;Agarwal, Chapla;Agarwal, Rajesh;Zarrelli, Armando;Di Fabio, Giovanni. And the article was included in Bioorganic & Medicinal Chemistry in 2021.Quality Control of 4-Hydroxy-3-methoxyphenethanol The following contents are mentioned in the article:

Curcumin is a bioactive natural compound with a wide range of pharmacol. properties, including antitumor activity; however, its clin. application has been limited because of its low solubility, stability, and bioavailability. In this study, a solid phase approach was proposed for the combinatorial synthesis of a mini library of the mimics of curcumin in good purity and yield. The non-effective findings in pancreatic cancer cells switched to strong growth inhibition and cell death efficacy for PC3 prostate cancer cells, and mimic 9, in which tyrosol (TYR) and homovanillyl alc. (HVA) units were linked by a phosphodiester bond, was quite effective not only in cell growth inhibition but also in causing strong cell death under the study conditions and treatments that were not effective in PANC1 cells. The results got more exciting when we also consider the findings in SW480 human colorectal carcinoma cell line, where the growth inhibitor effects were more in line with that of the PC3 cells, but the lack of cell death effect was more in line with the PANC1 cells. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Quality Control of 4-Hydroxy-3-methoxyphenethanol).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Quality Control of 4-Hydroxy-3-methoxyphenethanol

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Modulating Aβ aggregation by tyrosol-based ligands: The crucial role of the catechol moiety was written by Romanucci, Valeria;Garcia-Vinuales, Sara;Tempra, Carmelo;Bernini, Roberta;Zarrelli, Armando;Lolicato, Fabio;Milardi, Danilo;Di Fabio, Giovanni. And the article was included in Biophysical Chemistry in 2020.Safety of 4-Hydroxy-3-methoxyphenethanol The following contents are mentioned in the article:

The abnormal deposition of Aβ amyloid deposits in the brain is a hallmark of Alzheimer’s disease (AD). Based on this evidence, many current therapeutic approaches focus on the development of small mols. halting Aβ aggregation. However, due to the temporary and elusive structures of amyloid assemblies, the rational design of aggregation inhibitors remains a challenging task. Here we combine ThT assays and MD simulations to study Aβ aggregation in the presence of the natural compounds tyrosol (TY), 3-hydroxytyrosol (HDT), and 3-methoxytyrosol (homovanillyl alc. HVA). We show that albeit HDT is a potent inhibitor of amyloid growth, TY and HVA catalyze fibril formation. An inspection of MD simulations trajectories revealed that the different effects of these three mols. on Aβ_1-40 aggregation are ascribable to their capacity to arrange H-bonds network between the ligand (position C-3) and the peptide (Glu22). We believe that our results may contribute to the design of more effective and safe small mols. able to contrast pathogenic amyloid aggregation. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Safety of 4-Hydroxy-3-methoxyphenethanol).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Safety of 4-Hydroxy-3-methoxyphenethanol

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem