Category: 2380-78-1

Ethanol/1,4-dioxane/formic acid as synergistic solvents for the conversion of lignin into high-value added phenolic monomers was written by Wu, Zhen;Zhao, Xinxu;Zhang, Jun;Li, Xun;Zhang, Yu;Wang, Fei. And the article was included in Bioresource Technology in 2019.Recommanded Product: 4-Hydroxy-3-methoxyphenethanol The following contents are mentioned in the article:

In this study, a mixture solvent of ethanol/1,4-dioxane/formic acid (FA) is firstly reported to efficaciously depolymerize industrial lignin to produce high-value added phenolic monomers, in which 1,4-dioxane acts as lignin solvent, ethanol acts as solvent, reactant and in situ hydrogen donor, and FA acts as acid catalyst and in situ hydrogen donor. The effects of solvent composition and reaction conditions on the lignin conversion and product yields were explored, resulting in a low residue yield of 6.57% and a high phenolic monomers yield of 22.4% at 300 °C for 2 h when Kraft lignin was depolymerized in the mixture solvent of ethanol/1,4-dioxane/FA (10:10:2, volume/volume). Moreover, possible reaction mechanism on lignin depolymerization in the mixture solvent was illustrated, suggesting a favorable synergistic effect among the three components of the mixture solvent. In addition, the satisfactory applicability of the mixture solvent was approved through the feedstock adaptability and recyclability experiments This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Recommanded Product: 4-Hydroxy-3-methoxyphenethanol).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Recommanded Product: 4-Hydroxy-3-methoxyphenethanol

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

A New Family of Renewable Thermosets: Kraft Lignin Poly-adipates was written by Di Francesco, Davide;Rigo, Davide;Reddy Baddigam, Kiran;Mathew, Aji P.;Hedin, Niklas;Selva, Maurizio;Samec, Joseph S. M.. And the article was included in ChemSusChem in 2022.Application In Synthesis of 4-Hydroxy-3-methoxyphenethanol The following contents are mentioned in the article:

Thermosetting polymeric materials have advantageous properties and are therefore used in numerous applications. In this study, it was hypothesized and ultimately shown that thermosets could be derived from comparably sustainable sub-components. A two-step procedure to produce a thermoset comprising of Kraft lignin (KL) and the cross-linker adipic acid (AdA) was developed. The crosslinking was activated by means of an acetylating agent comprising isopropenyl acetate (IPA) to form a crosslinking mixture (CLM). The crosslinking was confirmed by FTIR and solid-state NMR spectroscopy, and the esterification reactions were further studied using model compounds When the KL lignin was mixed with the CLM, partial esterification occurred to yield a homogeneous viscous liquid that could easily be poured into a mold, as the first step in the procedure. Without any additions, the mold was heated and the material transformed into a thermoset by reaction of the two carboxylic acid-derivatives of AdA and KL in the second step. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Application In Synthesis of 4-Hydroxy-3-methoxyphenethanol).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Application In Synthesis of 4-Hydroxy-3-methoxyphenethanol

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

One-pot bio-derived ionic liquid conversion followed by hydrogenolysis reaction for biomass valorization: A promising approach affecting the morphology and quality of lignin of switchgrass and poplar was written by Carrozza, Chiara Francesca;Papa, Gabriella;Citterio, Attilio;Sebastiano, Roberto;Simmons, Blake A.;Singh, Seema. And the article was included in Bioresource Technology in 2019.Application In Synthesis of 4-Hydroxy-3-methoxyphenethanol The following contents are mentioned in the article:

The use of bio-derived ionic liquids (e.g., cholinium lysinate) in a one-pot process was evaluated on overall sugar and lignin yields as a function of two model woody and herbaceous feedstocks, switchgrass and poplar, with emphasis on the study of phys. and chem. alterations in lignin structure, by performing a detailed mass balance anal. and chem. characterization. Multiple chromatog. and spectroscopic anal. techniques were applied tracking lignin reactivity and partitioning during the ionic liquid one-pot conversion. Depolymerization efficiency of the lignin-rich residue derived from the whole process was investigated as a function of different temperatures and pressures during catalytic hydrogenolysis by Ni(SO)₄. This study validates the potential of ionic liquid one pot process as an integrated approach for full exploitation of lignocellulosic feedstocks. The insights gained will contribute to the design of future conversion routes for efficient biomass deconstruction and lignin valorization. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Application In Synthesis of 4-Hydroxy-3-methoxyphenethanol).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Application In Synthesis of 4-Hydroxy-3-methoxyphenethanol

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Antioxidant and Biological Activities of Hydroxytyrosol and Homovanillic Alcohol Obtained from Olive Mill Wastewaters of Extra-Virgin Olive Oil Production was written by Ricelli, Alessandra;Gionfra, Fabio;Percario, Zulema;De Angelis, Martina;Primitivo, Ludovica;Bonfantini, Veronica;Antonioletti, Roberto;Bullitta, Simonetta Maria;Saso, Luciano;Incerpi, Sandra;Pedersen, Jens Zacho. And the article was included in Journal of Agricultural and Food Chemistry in 2020.Synthetic Route of C9H12O3 The following contents are mentioned in the article:

Some constituents of the Mediterranean diet, such as extra-virgin olive oil (EVOO) contain substances such as hydroxytyrosol (HT) and its metabolite homovanillic alc. (HA). HT has aroused much interest due to its antioxidant activity as a radical scavenger, whereas only a few studies have been made on the HA mol. Both chem. synthesis and extraction techniques have been developed to obtain these mols., with each method having its advantages and drawbacks. In this study, we report the use of tyrosol from olive mill wastewaters as a starting mol. to synthesize HT and HA, using a sustainable procedure characterized by high efficiency and low cost. The effects of HT and HA were evaluated on two cell lines, THP-1 human leukemic monocytes and L-6 myoblasts from rat skeletal muscle, after treating the cells with a radical generator. Both HT and HA efficiently inhibited ROS production In particular, HT inhibited the proliferation of the THP-1 leukemic monocytes, while HA protected L-6 myoblasts from cytotoxicity. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Synthetic Route of C9H12O3).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Synthetic Route of C9H12O3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Metal-Organic Framework-Mediated Synthesis of One-Dimensional Nitrogen-Doped Molybdenum Carbide for the Cleavage of Lignin and Dimeric Lignin Model Compounds was written by Wang, Qiuyue;Su, Tianmei;Wang, Yu;Chen, Yufang;Lu, Xinqing;Ma, Rui;Fu, Yanghe;Zhu, Weidong. And the article was included in ACS Sustainable Chemistry & Engineering in 2020.Synthetic Route of C9H12O3 The following contents are mentioned in the article:

Molybdenum carbide (Mo₂C) has emerged as a remarkable catalyst for the cleavage of the aromatic carbon-oxygen (C_aryl-O) and alkyl carbon-oxygen (C_alkyl-O) in lignin and lignin model compounds However, the selectivity for the target product, that is phenol, is unsatisfactory due to the secondary alkylation reactions of the primarily produced phenol with the organic solvent used. Here, we report that a one-dimensional nitrogen-doped Mo₂C catalyst (N-Mo₂C@C) mediated from Mo-MOF via a “pyrolysis-carbothermal reduction” process shows a remarkably high selectivity toward phenol and monophenols in the valorization of aryl ethers and lignin because of its controllable phase composition and suitable valence state. The current study provides a method to develop efficient catalysts for lignin conversion into valuable chems. Selective cleavage of the aromatic carbon-oxygen bonds in lignin and lignin dimers can be achieved over a MOF-derived one-dimensional nitrogen-doped molybdenum carbide. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Synthetic Route of C9H12O3).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Synthetic Route of C9H12O3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

The secoiridoid profile of virgin olive oil conditions phenolic metabolism was written by Castillo-Luna, A.;Ledesma-Escobar, C. A.;Gomez-Diaz, R.;Priego-Capote, F.. And the article was included in Food Chemistry in 2022.Computed Properties of C9H12O3 The following contents are mentioned in the article:

The European Food Safety Authority highlights the beneficial effects of olive oil phenols, mainly, secoiridoids. Nevertheless, the metabolism of secoiridoids in humans has not been fully elucidated. This research evaluated the metabolism of secoiridoids in humans after intake of olive oils with diverse phenolic profiles. For this purpose, three extra virgin olive oils (EVOOs) were ingested by six volunteers at scheduled meals, and urine samples were collected the following morning for subsequent LC-MS/MS anal. Using untargeted anal., urinary metabolites revealed representative patterns associated with the various olive oil phenolic contents in absolute and relative terms. We were able to identify metabolites obtained through phase I, phase II, and microbial metabolism with discrimination between tyrosol and hydroxytyrosol derivatives Metabolism of phenols is differentially activated as a function of the olive oil secoiridoids content, and this proof-of-concept study shows how urinary metabolites represent olive oil phenolic content. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Computed Properties of C9H12O3).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Computed Properties of C9H12O3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Catalytic hydrothermal liquefaction of lignin for production of aromatic hydrocarbon over metal supported mesoporous catalyst was written by Feng, Li;Li, Xuhao;Wang, Zizeng;Liu, Bingzhi. And the article was included in Bioresource Technology in 2021.Product Details of 2380-78-1 The following contents are mentioned in the article:

Catalytic hydrothermal liquefaction (HTL) of lignin was examined at various temperature (250-310°C) and reaction time in the presence of different solvents (water, methanol and ethanol) with different metal supported on MCM-41 mesoporous catalyst. In case of ethanol solvent, the maximum bio-oil yield of 56.2 wt% was obtained with Ni-Al/MCM-41. However in case of water, bio-oil yield was (44.3 wt%); while significantly improves bio-oil yield for methanol solvent (48.1 wt%). It is indicated that alc. solvents promoted the lignin decomposition, while in the presence of catalyst; water solvent significantly improves lignin degradation Loading of Ni and Al on MCM-41, the acid strength of the catalyst increased, which enhanced lignin degradation From the GC-MS anal., the main G-type (ca.54%) phenolic compounds were produced with higher percentage of aromatic hydrocarbon compounds CHNS and GPC anal. showed that catalytic liquefaction encouraged hydrodeoxygenation, which produced lower oxygen content bio-oil with lower mol. weight This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Product Details of 2380-78-1).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Product Details of 2380-78-1

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Nutrition during pregnancy and lactation: New evidence for the vertical transmission of extra virgin olive oil phenolic compounds in rats was written by Lopez-Yerena, Anallely;Grases-Pinto, Blanca;Zhan-Dai, Sonia;Perez-Cano, Francisco J.;Lamuela-Raventos, Rosa M.;Rodriguez-Lagunas, Maria J.;Vallverdu-Queralt, Anna. And the article was included in Food Chemistry in 2022.Application In Synthesis of 4-Hydroxy-3-methoxyphenethanol The following contents are mentioned in the article:

Maternal breast milk provides the newborn with passive immunity and stimulates the maturation of the infant immune system. The aim of the present study was to evaluate the vertical transmission of phenolic compounds and their metabolites to offspring in rats fed with extra virgin olive oil (EVOO) during pregnancy and lactation. For this purpose, plasma and lactic serum from dams and plasma from offspring were analyzed by LC-ESI-LTQ-Orbitrap-MS. Both enzymic and microbial metabolites of hydroxytyrosol and tyrosol were detected in dam plasma and lactic serum. In addition, significant levels of phenolic compounds and their metabolites were found in offspring plasma. The concentration and number of hydroxytyrosol derivatives was higher than those of tyrosol and the microbial metabolites were found in the highest concentration The observed vertical transmission of EVOO phenolic compounds, whose health benefits are widely reported, provides further support for the importance of the maternal diet during pregnancy and lactation. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Application In Synthesis of 4-Hydroxy-3-methoxyphenethanol).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Application In Synthesis of 4-Hydroxy-3-methoxyphenethanol

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Effects of post-harvest fungal infection of apples on chemical characteristics of cider was written by Simonato, Barbara;Lorenzini, Marilinda;Zapparoli, Giacomo. And the article was included in LWT–Food Science and Technology in 2021.Product Details of 2380-78-1 The following contents are mentioned in the article:

The impact of fungal post-harvest infection of apple on the chem. composition of cider was investigated through a comparative anal. of ciders obtained from apples (Gala variety) sep. infected by five fungal species (Alternaria alternata, Botrytis cinerea, Diplodia seriata, Monilinia fructigena, and Penicillium expansum) and cider from sound apples. The content of several flavor-active mols. belonging to different chem. groups, such as alcs., esters, acids, aldehydes, phenols, and lactones, significantly varied among ciders. Particularly, cider from sound apples had a higher concentration of Et ester acetate, fatty acid Et esters and fatty acids, mols. that contribute to fruity and sweet scent. Principal component anal. well discriminated ciders, evidencing species-specific fungal effect. Differences in precursor availability in juices and biosynthesis pathways in fungi could explain changes in aroma profile of ciders. This study provides information on the potential risk to produce cider from infected apples due to the possible quality depreciation. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Product Details of 2380-78-1).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Product Details of 2380-78-1

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Synthesis of New Tyrosol-Based Phosphodiester Derivatives: Effect on Amyloid β Aggregation and Metal Chelation Ability was written by Romanucci, Valeria;Giordano, Maddalena;De Tommaso, Gaetano;Iuliano, Mauro;Bernini, Roberta;Clemente, Mariangela;Garcia-Vinuales, Sara;Milardi, Danilo;Zarrelli, Armando;Di Fabio, Giovanni. And the article was included in ChemMedChem in 2021.COA of Formula: C9H12O3 The following contents are mentioned in the article:

Alzheimer’s disease (AD) is a multifactorial pathol. that requires multifaceted agents able to address its peculiar nature. Increasing evidence has shown that aggregation of amyloid β (Aβ) and oxidative stress are strictly interconnected, and their modulation might have a pos. and synergic effect in contrasting AD-related impairments. Herein, a new and efficient fragment-based approach towards tyrosol phosphodiester derivatives (TPDs) has been developed starting from suitable tyrosol building blocks and exploiting the well-established phosphoramidite chem. The antioxidant activity of new TPDs has been tested as well as their ability to inhibit Aβ protein aggregation. In addition, their metal chelating ability has been evaluated as a possible strategy to develop new natural-based entities for the prevention or therapy of AD. Interestingly, TPDs containing a catechol moiety have demonstrated highly promising activity in inhibiting the aggregation of Aβ₄₀ and a strong ability to chelate biometals such as Cu^II and Zn^II. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1COA of Formula: C9H12O3).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.COA of Formula: C9H12O3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem