Category: 23783-42-8

Bartolec, Boris published the artcileEmergence of Compartments Formed from Unconventional Surfactants in Dynamic Combinatorial Libraries, Computed Properties of 23783-42-8, the main research area is combinatorial library self assembly membrane.

Assembly processes can drive the selection of self-assembling mols. in dynamic combinatorial libraries, yielding self-synthesizing materials. We now show how such selection in a dynamic combinatorial library made from an amphiphilic building block which, by itself, assembles into micelles, can yield membranous aggregates ranging from vesicles to sponge phases. These aggregates are made from a mixture of unconventional surfactant mols., showing the power of dynamic combinatorial selection approaches for the discovery of new, not readily predictable, self-assembly motifs.

Langmuir published new progress about Aggregates. 23783-42-8 belongs to class ethers-buliding-blocks, name is 2,5,8,11-Tetraoxatridecan-13-ol, and the molecular formula is C9H20O5, Computed Properties of 23783-42-8.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Yiu, Asteria published the artcileFacile Synthesis of Novel Thermo-Responsive Polyvalerolactones with Tunable LCSTs, COA of Formula: C9H20O5, the main research area is thermoresponsive polyvalerolactone biodegradable tunable lower critical solution temperature; oligoethylene glycol functionalized polyvalerolactone thermal tunable.

Thermoresponsive polymers have emerged as promising candidates for biomedical applications. Seven novel oligoethylene glycol (OEG) functionalized polyvalerolactones P1-P7 are synthesized from poly(α-allyl-δ-valerolactone) via thiol-ene addition post-polymerization modification. All seven polymers exhibit thermoresponsive behavior with lower critical solution temperatures (LCSTs) ranging from 13.8 to 92.2°C. Polymers P5-P7 are synthesized via thiol-ene addition reaction using two thiol mixtures at three different ratios. LCSTs of P5-P7 fall in between those of P1 and P2, and exhibit a linear relationship, indicating a tunable thermoresponsive system. This newly developed system offers great control for a desired thermoresponsive biocompatible, biodegradable polymeric system with desired LCSTs.

Macromolecular Chemistry and Physics published new progress about Aggregates. 23783-42-8 belongs to class ethers-buliding-blocks, name is 2,5,8,11-Tetraoxatridecan-13-ol, and the molecular formula is C9H20O5, COA of Formula: C9H20O5.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Xie, Heping published the artcileLow-energy-consumption electrochemical CO2 capture driven by biomimetic phenazine derivatives redox medium, Recommanded Product: 2,5,8,11-Tetraoxatridecan-13-ol, the main research area is carbon dioxide proton coupled electron transfer electrolysis redox reaction.

To reduce the energy consumption of CO2-capture methods, proton carriers can be used to drive the CO2 capture in a pH-swing way via the proton coupled electron transfer (PCET) reactions, which are electrochem. regenerable by electrolysis, surpassing the energy-intensive thermal regeneration of traditional monoethanolamine (MEA) absorption method in terms of energy efficiency. However, the low solubility of PCET organics limits its CO2 capture capacity and thus the application. We develop a low energy consuming, high-capacity CO2-capture cell using a phenazine-based organic as the proton carrier as the PCET redox medium, which has high proton capacity and fast PCET kinetics. The quasi-reversible redox-PCET of the phenazine derivative effectively swings the pH of NaHCO3/Na2CO3 aqueous electrolyte at the cathode and the anode, which work as the CO2 absorption/desorption half-cell resp. This electrochem. CO2-capture cell with an optimal derivative (7,8-dihydroxyphenazine-2-sulfonic acid, noted as DHPS) demonstrates a 95.8% average current efficiency at 10 mA cm-2 and a superior low-electrolysis energy consumption of 0.49 GJ per ton of CO2.

Applied Energy published new progress about Absorption. 23783-42-8 belongs to class ethers-buliding-blocks, name is 2,5,8,11-Tetraoxatridecan-13-ol, and the molecular formula is C9H20O5, Recommanded Product: 2,5,8,11-Tetraoxatridecan-13-ol.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Stjerndahl, Maria published the artcileCleavable Surfactants: A Comparison between Ester, Amide, and Carbonate as the Weak Bond, Name: 2,5,8,11-Tetraoxatridecan-13-ol, the main research area is ester amide carbonate hydrolysis gemini cleavable surfactant property.

Cleavable surfactants, i.e., surfactants in which a weak bond has deliberately been inserted into the mol., are of interest when remaining surface-active material at a surface can cause problems. Ester and amide bonds are established as week linkages in surfactants but these generate an acid when they hydrolyze. For some applications, acidic degradation products are unwanted. Surfactants with a carbonate bond between the polar headgroup and the hydrophobic tail are of interest for such purposes. In this article, we compare the phys.-chem. properties of nonionic carbonate surfactants with those of the corresponding ester and amide surfactants. The half-lives of the different cleavable surfactants are also compared and it was found that a carbonate bond is slightly more stable to alk. hydrolysis than an ester bond when present in otherwise identical structures. A nonionic gemini surfactant with a carbonate bond in the spacer, which on hydrolysis decomposes into two identical single-tailed nonionic amphiphiles, is also presented. The hydrolysis kinetics for this surfactant was studied in some detail and it was found that it degrades much faster at low temperature than at higher temperature This anti-Arrhenius type of hydrolysis kinetics is proposed to be due to the reverse solubility vs. temperature behavior of ethoxylated surfactants.

Journal of Surfactants and Detergents published new progress about Cloud point. 23783-42-8 belongs to class ethers-buliding-blocks, name is 2,5,8,11-Tetraoxatridecan-13-ol, and the molecular formula is C9H20O5, Name: 2,5,8,11-Tetraoxatridecan-13-ol.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Rao, Zi-Kun published the artcileDual thermo-responsive amphiphilic alternating copolymers: one-pot synthesis and the temperature-induced self-assembly, Application of 2,5,8,11-Tetraoxatridecan-13-ol, the main research area is copolymer self assembly.

Abstract: Synthesis and self-assembly of stimuli-responsive amphiphilic alternating copolymers (AAC) are an emerging land of tremendous possibilities. Herein, by combining backbone polyethylene glycol (PEG) with pendent oligo-polyglycol simultaneously, two alternating LCST segments are knitted through enzymic synthesis, giving a series of alternating poly[(PEG400-a-succinic acid)-co-(diol(3EG)-a-succinic acid)] (PPSDS) for the first time. All the PPSDSs show only one-step sharp temperature responsiveness in transmittance-temperature curve owing to stabilization effect of PEG400. The cloud points can be linearly controlled by simply adjusting the feeding ratio of PEG400/diol-3EG. Referring to published works and 1H-NMR spectra in D2O, all the obtained AAC formed penetrable nanovesicles under 4°C. The TEM and 1H-NMR results confirmed that when heated to 18°C, PPSDS of “”9/1″” transformed from nanovesicles to large-compound micelles due to large hydrophobic volume, while other PPSDS of “”8/2, 7/3, 6/4″” retained the vesicle structures, except that the hydrophilic layer turned from PEG400 + diol(3EG) to PEG400 alone, leading to the size reduction The temperature-controlled size “”expansion and contraction”” of nanovesicles was unique for AAC, which was potentially good for enhancing loading rate. Further heating above cloud point resulted in the destruction of nanostructures and irregular intermol. aggregations. The first reported dual temperature-responsive AAC was innovative in structure design, providing a potential opportunity for the design and synthesis of controllable self-assemble structures and smart biomacromols. in biomedical applications.

Journal of Materials Science published new progress about Amphiphiles. 23783-42-8 belongs to class ethers-buliding-blocks, name is 2,5,8,11-Tetraoxatridecan-13-ol, and the molecular formula is C9H20O5, Application of 2,5,8,11-Tetraoxatridecan-13-ol.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Zhang, Dapeng published the artcileOne-Component Multifunctional Sequence-Defined Ionizable Amphiphilic Janus Dendrimer Delivery Systems for mRNA, Recommanded Product: 2,5,8,11-Tetraoxatridecan-13-ol, the main research area is ionizable amphiphilic Janus dendrimer delivery system mRNA.

Efficient viral or nonviral delivery of nucleic acids is the key step of genetic nanomedicine. Both viral and synthetic vectors have been successfully employed for genetic delivery with recent examples being DNA, adenoviral, and mRNA-based Covid-19 vaccines. Viral vectors can be target specific and very efficient but can also mediate severe immune response, cell toxicity, and mutations. Four-component lipid nanoparticles (LNPs) containing ionizable lipids, phospholipids, cholesterol for mech. properties, and PEG-conjugated lipid for stability represent the current leading nonviral vectors for mRNA. However, the segregation of the neutral ionizable lipid as droplets in the core of the LNP, the “”PEG dilemma””, and the stability at only very low temperatures limit their efficiency. Here, we report the development of a one-component multifunctional ionizable amphiphilic Janus dendrimer (IAJD) delivery system for mRNA that exhibits high activity at a low concentration of ionizable amines organized in a sequence-defined arrangement. Six libraries containing 54 sequence-defined IAJDs were synthesized by an accelerated modular-orthogonal methodol. and coassembled with mRNA into dendrimersome nanoparticles (DNPs) by a simple injection method rather than by the complex microfluidic technol. often used for LNPs. Forty four (81%) showed activity in vitro and 31 (57%) in vivo. Some, exhibiting organ specificity, are stable at 5°C and demonstrated higher transfection efficiency than pos. control experiments in vitro and in vivo. Aside from practical applications, this proof of concept will help elucidate the mechanisms of packaging and release of mRNA from DNPs as a function of ionizable amine concentration, their sequence, and constitutional isomerism of IAJDs.

Journal of the American Chemical Society published new progress about Amphiphiles. 23783-42-8 belongs to class ethers-buliding-blocks, name is 2,5,8,11-Tetraoxatridecan-13-ol, and the molecular formula is C9H20O5, Recommanded Product: 2,5,8,11-Tetraoxatridecan-13-ol.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Xie, Zhichao published the artcileAll-Solid-State Vertical Three-Terminal N-Type Organic Synaptic Devices for Neuromorphic Computing, Recommanded Product: 2,5,8,11-Tetraoxatridecan-13-ol, the main research area is polythiophene artificial synaptic device neuromorphic computing handwritten digital dataset.

Artificial synaptic devices are the basic composition units for neuromorphic computing processors that realize massive parallel computing. However, the n-type organic transistors have failed to achieve good performance as an artificial synaptic device for neuromorphic computing until now. Here, a vertical three-terminal n-type organic artificial synapse (TNOAS) using a lithium ion-based organic dielec. and the n-type donor-acceptor (D-A) conjugated polymer-naphthalene-1,4,5,8-tetracarboxylic-diimide-thiophene-vinyl-thiophene (NDI-gTVT) as the channel is proposed. The TNOAS achieves nonvolatile conductance modulation with high c.d. operation (≈10 KA cm-2) at low voltage and mimics the basic functions of biol. synapses, such as long-term synaptic plasticity and paired-pulse facilitation. The min. energy consumption of a response event triggered by a single action potential is 6.16 pJ, which can be comparable with p-type counterparts. Moreover, simulation using handwritten digital datasets exhibit a high recognition accuracy of 94%.

Advanced Functional Materials published new progress about Digital data. 23783-42-8 belongs to class ethers-buliding-blocks, name is 2,5,8,11-Tetraoxatridecan-13-ol, and the molecular formula is C9H20O5, Recommanded Product: 2,5,8,11-Tetraoxatridecan-13-ol.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Kim, Changkyun published the artcileC70-based aqueous-soluble fullerene for the water composition-tolerant performance of eco-friendly polymer solar cells, SDS of cas: 23783-42-8, the main research area is water soluble fullerene polymer solar cell aggregation.

Eco-friendly polymer solar cells (eco-PSCs) based on aqueous-soluble conjugated materials have recently received great research attention. In this work, we report the development of an aqueous-processable C70-based fullerene derivative (PC71BO15) for eco-PSCs processed by water/ethanol co-solvents. The desirable aggregation behavior and enhanced light absorption ability of PC71BO15 have enabled the fabrication of PPDT2FBT-A:PC71BO15-based eco-PSCs with power conversion efficiencies (PCEs) of up to 2.51%, which is the highest value reported to date for aqueous-processed PSCs. These PPDT2FBT-A:PC71BO15 eco-PSCs exhibit significantly higher PCEs than those of the reference PPDT2FBT-A:PC61BO15 devices over all device-processable water/ethanol compositions At the optimal water/ethanol composition (volume/volume = 15 : 85), the PCE of the PPDT2FBT-A:PC71BO15 eco-PSCs is 73% higher than that of the PC61BO15-based counterparts, as a result of enhanced light absorption. Importantly, the PC71BO15-based eco-PSCs show much higher tolerance in their PCEs to the water/ethanol composition For example, the PCEs of the PPDT2FBT-A : PC71BO15 eco-PSCs at a 30 : 70 water/ethanol ratio maintain 89% of the optimal performance at a 15 : 85 ratio, whereas the PC61BO15-based devices only maintain 45%. This large difference in terms of water-tolerant behavior is mainly related to the different aggregation behaviors between PC71BO15 and PC61BO15 in blend films, which are carefully investigated using elec., optical and morphol. characterizations. This high water composition-tolerance affords an excellent reproducibility of the PC71BO15-based eco-PSCs with eco/human-friendly aqueous processing under ambient conditions.

Journal of Materials Chemistry C: Materials for Optical and Electronic Devices published new progress about Aggregation. 23783-42-8 belongs to class ethers-buliding-blocks, name is 2,5,8,11-Tetraoxatridecan-13-ol, and the molecular formula is C9H20O5, SDS of cas: 23783-42-8.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Chen, Jiali published the artcileHydrogen-bond super-amphiphile based drug delivery system: design, synthesis, and biological evaluation, Recommanded Product: 2,5,8,11-Tetraoxatridecan-13-ol, the main research area is hydrogen bond amphiphile drug delivery system.

Drug delivery systems (DDSs) show great application prospects in tumor therapy. So far, phys. encapsulation and covalent grafting were the two most common strategies for the construction of DDSs. However, phys. encapsulation-based DDSs usually suffered from low drug loading capacity and poor stability, and covalent grafting-based DDSs might reduce the activity of original drug, which greatly limited their clin. application. Therefore, it is of great research value to design a new DDS with high drug loading capacity, robust stability, and original drug activity. Herein, we report a super-amphiphile based drug delivery system (HBS-DDS) through self-assembly induced by hydrogen bonds between amino-substituted N-heterocycles of the 1,3,5-triazines and hydrophilic carmofur (HCFU). The resulting HBS-DDS had a high drug loading capacity (38.1%) and robust stability. In addition, the drug delivery system exhibited pH-triggered size change and release of drugs because of the pH responsiveness of hydrogen bonds. In particular, the anticancer ability test showed that the HBS-DDS could be efficiently ingested by tumor cells, and its half-maximal inhibitory concentration (IC50 = 3.53μg mL-1) for HeLa cells was close to that of free HCFU (IC50 = 5.54μg mL-1). The hydrogen bond-based DDS represents a potential drug delivery system in tumor therapy.

RSC Advances published new progress about Amphiphiles. 23783-42-8 belongs to class ethers-buliding-blocks, name is 2,5,8,11-Tetraoxatridecan-13-ol, and the molecular formula is C9H20O5, Recommanded Product: 2,5,8,11-Tetraoxatridecan-13-ol.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Jiang, Meiyu published the artcileSelf-assembly of Amphiphilic Porphyrins To Construct Nanoparticles for Highly Efficient Photodynamic Therapy, Application In Synthesis of 23783-42-8, the main research area is amphiphilic porphyrin preparation PDT cancer nanoparticle; amphiphilic; nanoparticles; photodynamic therapy; self-assembly; triphenylphosphine.

Hydrophobic photosensitizers greatly affect cell permeability and enrichment in tumors, but they cannot be used directly for clin. applications because they always aggregate in water, preventing their circulation in the blood and accumulation in tumor cells. As a result, amphiphilic photosensitizers are highly desirable. Although nanomaterial-based photosensitizers can solve water solubility, they have the disadvantages of complicated operation, poor reproducibility, low drug loading, and poor stability. In this work, an efficient synthesis strategy is proposed that converts small mols. into nanoparticles in 100% aqueous solution by mol. assembly without the addition of any foreign species. Three photosensitizers with triphenylphosphine units and ethylene glycol chains of different lengths, TPP-PPh3, TPP-PPh3-2PEG and TPP-PPh3-4PEG, were synthesized to improve amphiphilicity. Of the three photosensitizers, TPP-PPh3-4PEG is the most efficient (singlet oxygen yield: 0.89) for tumor photodynamic therapy not only because of its definite constituent, but also because its amphiphilic structure allows it to self-assemble in water.

Chemistry – A European Journal published new progress about Amphiphiles. 23783-42-8 belongs to class ethers-buliding-blocks, name is 2,5,8,11-Tetraoxatridecan-13-ol, and the molecular formula is C9H20O5, Application In Synthesis of 23783-42-8.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem