Category: 2062-98-8

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 2062-98-8, name is Perfluoro(2-methyl-3-oxahexanoyl) fluoride belongs to ethers-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. COA of Formula: C6F12O2

In a four-necked flask equipped with a stirrer, a thermometer, a dropping funnel, and a reflux condenser (anhydrous calcium chloride at the top),Add 1,3-dimethyl-1,3,5-triazine (2.76 g, 24 mmol)And dichloromethane (30 mL),After stirring to dissolve, add triethylamine (3.25mL, 26mmol) and cool to 0 C.Was added dropwise with stirring hexafluoropropylene oxide dimer (6.64g, 20mmol),After 1 hour, the addition was completed. After the addition, the reaction was stirred at 0 C for 3 hours.The reaction mixture was washed with 10% sodium hydroxide solution (50 mL) and separated. The organic layer was washed with water, dried over anhydrous sodium sulfate, and the solvent was spin-dried.The residue was separated and purified by column chromatography [dichloromethane / methanol (v / v) = 20/1],7.86 g of a colorless transparent liquid fluorinated intermediate I-1 were obtained,Yield: 92%.

The synthetic route of 2062-98-8 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Ruyuan Dongyang Guangfu Co., Ltd.; Li Yitao; Lan Xiaobin; Hou Qinqing; Yang Feng; Jia Yuan; Cheng Zhen; (9 pag.)CN110818650; (2020); A;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Related Products of 2062-98-8, The chemical industry reduces the impact on the environment during synthesis 2062-98-8, name is Perfluoro(2-methyl-3-oxahexanoyl) fluoride, I believe this compound will play a more active role in future production and life.

[0097] Compound (2b) (620 g) was put into a 2L autoclave made of hastelloy C and stirred, while bubbling nitrogen gas. While maintaining the internal temperature at from 25 to 35 DEG C, compound (4b) (1830 g) was dropwise added over a period of 8 hours thereto. After completion of the dropwise addition, bubbling of nitrogen gas was further continued to remove HF and excess compound (4b) and to obtain 2245 g of compound (3b). Using compound (3b) (1800 g), a fluorination reaction was carried out in the same manner as in Example 2 to obtain compound (1b) in a yield of 69%.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Perfluoro(2-methyl-3-oxahexanoyl) fluoride, other downstream synthetic routes, hurry up and to see.

Reference:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 2062-98-8, name is Perfluoro(2-methyl-3-oxahexanoyl) fluoride, A new synthetic method of this compound is introduced below., COA of Formula: C6F12O2

F[CF(CF3)CF2O]4CF(CF3)C(O)F, a precursor of hydrofluoroether F[CF(CF3)CF2O]5CH3, was formed by pentapolymerization of hexafluoropropylene oxide. To the reaction vessel, potassium fluoride (10.0 g), hexafluoropropylene oxide dimer (150.0 g) and diethylene glycol dimethyl ether (2.5 L) were added at 15 C under stirring.To the round bottom flask was introduced hexafluoropropylene oxide (830 g, 5.0 mol) over 1 hour.The lower layer of the acyl fluoride phase product is mainly composed of a hexafluoropropylene oxide tetramer, a hexafluoropropylene oxide pentamer and a hexafluoropropylene oxide hexamer, and the yield of the hexafluoropropylene oxide pentamer is 65%. The crude product was further purified by distillation to obtain a product of a hexafluoropropylene oxide pentamer having a purity of 99% as determined by gas chromatography, and used.In the next alkylation reaction. The structure of the product was characterized by infrared spectroscopy and 19F NMR.

The synthetic route of 2062-98-8 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Tianjin Changlu Chemical New Materials Co., Ltd.; Yan Rui; He Guangrui; (15 pag.)CN109608312; (2019); A;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Synthetic Route of 2062-98-8, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 2062-98-8, name is Perfluoro(2-methyl-3-oxahexanoyl) fluoride belongs to ethers-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.

Example 2; Example 2-1; [0175] Example for Preparation of CH2CHCH(OCH3) CH2OCOCF (CF3)OCF2CF2CF3; [0176] CH2CHCH(OCH3)CH2OH (270 g) was charged together with NaF (334 g) into a 2 L pressure resistant reactor equipped with a reflux condenser in which a coolant at 20 C. circulated, and stirred at -10 C. While discharging by-product HF formed by the reaction out of the system from the reflux condenser on the upper portion by bubbling nitrogen gas to the reactor, FCOCF(CF3)OCF2CF2CF3 (1055 g) was dropwise added over a period of 1.5 hours. At this time, the temperature was adjusted so that the internal temperature of the reactor would be at most 0 C. After completion of the dropwise addition, stirring was carried out at 30 C. for 18 hours and then the reaction was terminated. [0177] NaF contained in the crude liquid after completion of the reaction was collected by filtration to obtain a crude product (981 g) (yield 86.4%). As a result of the analysis by NMR, the above-identified mixture was obtained as a liquid mixture with FCOCF(CF3)OCF2CF2CF3. The results of analysis of the above-identified compound are as follows. [0178] 1H-NMR(300.4 MHz, solvent:CDl3, standard:TMS) delta (ppm):3.29(s, 3H), 3.85-3.90(m, 1H), 4.24-4.45(m, 2H), 5.34(s, 1H), 5.39(d,J=8.4 Hz, 1H), 5.59-5.71(m, 1H). [0179] 19F-NMR(282.7 MHz, solvent:CDCl3, standard:CFCl3) delta (ppm): -81. 8(3F), -82.6(3F), -79.9-87.5(2F), -130.2(2F), -132.3(1F).

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Perfluoro(2-methyl-3-oxahexanoyl) fluoride, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; ASAHI GLASS COMPANY LIMITED; US2003/216595; (2003); A1;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 2062-98-8, name is Perfluoro(2-methyl-3-oxahexanoyl) fluoride, A new synthetic method of this compound is introduced below., Recommanded Product: 2062-98-8

To a 3 -neck flask equipped with a temperature probe, magnetic stir bar, water- cooled condenser, and addition funnel was charged sodium borohydride (16.0 g, 423 mmol), and tetraethylene glycol dimethyl ether (125 mL). 2,3,3,3-Tetrafluoro-2- (1,1,2,2,3, 3, 3-heptafluoropropoxy)propanoyl fluoride (100 g, 301 mmol) was added dropwise to the resultant mixture. After complete addition, the reaction mixture was heated to reflux and stirred overnight. The mixture was then allowed to cool to room temperature followed by the dropwise addition of methanol (100 mL) and H2O (150 mL). The mixture was then transferred to a separatory funnel and the fluorous phase was collected and then distilled (46.1 C, 40 ton) to afford 2,3,3,3-tetrafluoro-2-(l, 1,2,2,3,3- heptafluoropropoxy)propan-l-ol (67.5 g, 71%) as a colorless liquid. The isolated compound was used in the next step. (0204) To a 3-neck flask equipped with a temperature probe, distillation head, overhead stirrer, and under N2 was charged TiCU (7.9 mL, 72 mmol). 2,3,3,3-Tetrafluoro-2- (l,l,2,2,3,3,3-heptafluoropropoxy)propan-l-ol (15.1 g, 47.8 mmol) was added dropwise with stirring and the resultant mixture was heated to 40 C followed by a 30 min stir. The mixture was then allowed to cool to room temperature followed by the dropwise addition of tetraethylene glycol dimethyl ether (45 mL). Exotherms reaching approximately 50 C were observed. The resultant mixture was allowed to warm to room temperature followed by the addition of zinc dust (9.1 g, 140 mmol) in one portion. The resultant reaction mixture was raised to 85 C. After a 3 h stir, the temperature was slowly raised to 225 C and distillate was collected with the distillation head temperature reaching 69 C affording the title compound (4.1 g, 31%) as a colorless liquid.

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.

Reference:
Patent; 3M INNOVATIVE PROPERTIES COMPANY; SMITH, Sean M.; LAMANNA, William M.; COSTELLO, Michael G.; BULINSKI, Michael J.; (35 pag.)WO2017/195070; (2017); A1;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 2062-98-8 as follows. name: Perfluoro(2-methyl-3-oxahexanoyl) fluoride

Under a nitrogen atmosphere, ethyl 3-dimethylam- inoethyl acrylate (1.43 g) was dissolved in toluene (10 ml), and pyridine (0.8 g) was added at room temperature. Perfluoro(1 -(1 -propoxy) propionic acid) fluoride (perfluoro(2- methyl-3-oxa-hexanoyl) fluoride) (3.2 g) was dropwise added thereto, followed by stirring for 10 hours at the same temperature. Water (20 ml) was added to the reaction mixture, and the organic phase was separated. Further, the aqueous phase was extracted with toluene (10 ml), and the extract was combined with the previous organic phase. This organic phase was dried over anhydrous magnesium sulfate, and the solvent was distilled oil to obtain 4.5 g of a compound represented by the following formula.

According to the analysis of related databases, 2062-98-8, the application of this compound in the production field has become more and more popular.

Reference:
Patent; ASAHI GLASS COMPANY, LIMITED; MORIZAWA, Yoshitomi; TAKAHIRA, Yusuke; (32 pag.)US2016/295864; (2016); A1;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 2062-98-8 as follows. category: ethers-buliding-blocks

To a solution of hydroxyacetone (7.4 g) and pyridine (8.1 ml) in ethyl acetate (100 ml), undecafluoro-(2-methyl-3-oxahexanoic acid)fluoride (10 g) was added dropwise at room temperature (25 C.). After stirring at room temperature for 2 hours, the reaction mixture was poured into diluted hydrochloric acid. After separation, the organic layer was washed with water and a saturated sodium chloride solution and dried with magnesium sulfate. The concentrated residue was purified by column chromatography (developing solvent: ethyl acetate/hexane), to obtain Compound B (10.2 g, 88%).1H NMR (CDCl3) delta 2.22 (s, 3H), 4.85 (d, J=16.2 Hz, 1H), 4.96 (d, J=16.2 Hz, 1H)19FNMR (CDCl3) delta -80.3 (1F), -81.8 (3F), -82.5 (3F), -86.7 (1F), -130.2 (2F), -132.8 (1F)

According to the analysis of related databases, 2062-98-8, the application of this compound in the production field has become more and more popular.

Reference:
Patent; FUJIFILM Corporation; US2009/18350; (2009); A1;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Synthetic Route of 2062-98-8, A common heterocyclic compound, 2062-98-8, name is Perfluoro(2-methyl-3-oxahexanoyl) fluoride, molecular formula is C6F12O2, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

In an argon atmosphere, put 0.50 g (4.2 mmol) of 4-hydroxystyrene into a three-necked flask, add 20 mL of dichloromethane, and add 1.99 g (6 mmol) of hexafluoropropylene oxide di containing acid fluoride end groups while stirring. Polymer (CF3CF2CF2OCF (CF3) COF, provided by Zhejiang Huanxin Fluoro Material Co., Ltd., recorded as FEOCOF), after the addition, 0.05 mL (0.0007 mmol) DMF was added, and 0.4 mL (0.003 mmol) of dry After triethylamine was added dropwise, the reaction was stirred at 40 C for 4h. After the reaction, 20 mL of deionized water was added and extracted with dichloromethane (20 mL × 3). The organic phases were combined and dried over MgSO 4, filtered, and rotary evaporated to obtain a crude product. The crude product was separated by silica gel column chromatography (washed with petroleum ether). Remover) to obtain a colorless slightly viscous liquid, the target product, with a yield of 99.5%

The synthetic route of 2062-98-8 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Shaanxi Normal University; Yang Le; Chen Jiangang; Liu Zhaotie; Zhang Qiyu; Li Ruiqing; Shen Shukun; Liu Zhongwen; (11 pag.)CN110776426; (2020); A;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Adding a certain compound to certain chemical reactions, such as: 2062-98-8, name is Perfluoro(2-methyl-3-oxahexanoyl) fluoride, belongs to ethers-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 2062-98-8, SDS of cas: 2062-98-8

General procedure: To a magnetic stirred solution of 15.6 g triethylamine (0.15 mol) and 10.10 g allyl alcohol (0.17 mol) in anhydrous chloroform (150 mL) in a dry three-neck flask, 74.90 g perfluoro-2,5-dimethyl-3,6-dioxa-nonanoyl fluoride (0.15 mol) were added dropwise over a period of 3 h under agitation at 0 C. The reaction mixture was stirred for a further 12 h, with the temperature of reaction mass being maintained at room temperature. Distilled water was added to extract the triethylammonium fluoride and the unreacted allyl alcohol at the end of the reaction. The chloroform layer was dried over anhydrous sodium sulfate, and the major portion of the chloroform was distilled off in the vacuum of a water-jet pump over water. Additionally, the crude product was obtained and distilled under reduced pressure to give the pure product.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Perfluoro(2-methyl-3-oxahexanoyl) fluoride, other downstream synthetic routes, hurry up and to see.

Reference:
Article; Shi, Xiang; Shi, Hongxin; Wu, Hongke; Shen, HaiMin; Research on Chemical Intermediates; vol. 44; 9; (2018); p. 5091 – 5105;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Adding a certain compound to certain chemical reactions, such as: 2062-98-8, name is Perfluoro(2-methyl-3-oxahexanoyl) fluoride, belongs to ethers-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 2062-98-8, COA of Formula: C6F12O2

While the solution containing compound (c1-1) was stirred at 0C, 1.7 g of triethylamine was added. Then, 4.4g of 2-(heptafluoropropoxy)-2,3,3,3-tetrafluoropropionic acid fluoride (compound d1-1) was dropwise added. After completionof dropwise addition, the solution was stirred at room temperature for 1 hour to obtain a solution containingcompound (m1-1). The solution containing compound (m1-1) was poured into ice water, followed by extraction three times withethyl acetate. Then, the resulting organic layer was dried over magnesium sulfate to remove the solvent, and the residuewas purified by silica gel column chromatography (eluent: ethyl acetate/hexane=1/2 (volume ratio)) to obtain 2.0 g ofcompound (m1-1). Compound (m1-1) was identified by 1H-NMR and 19F-NMR. NMR spectra of compound (m1-1): 1H-NMR (300.4MHz, solvent:CDCl3, standard:TMS) delta (ppm): 1.85(s, 6H), 4.27(t, J=4.8, 2H), 4.52(t, J=4.8, 2H),5.87(dd, J=10.5, 10.8, 1 H), 6.16(dd, J=10.5, 17.1, 1H), 6.45(dd, J=17.1, 17.4, 1H), 6.92(d, J=9.0, 2H), 7.90(d,J=9.0, 2H). 19F-NMR(282.7MHz, solvent:CDCl3, standard:CFCl3)delta5(ppm):-132.0(m, 1F), – 129.6(m, 2F), -85.4(m, 1F), -81.2(m, 6F), -79.5(m, 1F).

At the same time, in my other blogs, there are other synthetic methods of this type of compound, Perfluoro(2-methyl-3-oxahexanoyl) fluoride, and friends who are interested can also refer to it.

Reference:
Patent; Asahi Glass Company, Limited; ITO, Masahiro; TSURUOKA, Kaori; EP2792665; (2014); A1;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem