Category: 2050-46-6

Reference of 2050-46-6, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 2050-46-6, name is 1,2-Diethoxybenzene, This compound has unique chemical properties. The synthetic route is as follows.

EXAMPLE 7 Synthesis of 1,2-Diethoxy-4-(5′-hexynoyl)benzene STR23 A solution of 1,2-diethoxybenzene (1.66 g, 10.0 mmol) and 5-hexynoyl chloride (1.31 g, 1.00 eq) in methylene chloride (20 ml) is cooled to -60 C. Stannic chloride (2.66 g, 1.02 eq) is slowly added to the solution and the mixture is stirred at -60 C. for 10 minutes. The reaction mixture is quenched with 3N HCl and the layers are separated. The methylene chloride layer is extracted with 3N HCl, then extracted twice with water, and concentrated in vacuo. The yield of the crude 1,2-diethoxy-4-(5′-hexynoyl)benzene is 2.67 g.

The chemical industry reduces the impact on the environment during synthesis 1,2-Diethoxybenzene. I believe this compound will play a more active role in future production and life.

Reference:
Patent; Norwich Eaton Pharmaceuticals, Inc.; US4982006; (1991); A;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 2050-46-6, name is 1,2-Diethoxybenzene, This compound has unique chemical properties. The synthetic route is as follows., Application In Synthesis of 1,2-Diethoxybenzene

G. 2-(3,4-Diethoxybenzoyl)[cis]cyclohexanecarboxylic Acid Prepared from 1,2-diethoxybenzene and cis-hexahydrophthalic anhydride as described for compound A. M.p.: low melting solid. 1 H-NMR(CDCl3): 1.28-2.27(m, 14H, 833 cyclohexane H, 2*C–CH3); 2.66(quintet, J=4.8 Hz, 1H, cyclohexane H); 3.91-3.97(m, 1H, C–CH(C)–C); 4.01-4.25(m, 4H, 2*O–CH2); 6.89(d, J=8.2 Hz, 1H, arom. H); 7.48-7.53 (m, 2H, arom. H)

According to the analysis of related databases, 2050-46-6, the application of this compound in the production field has become more and more popular.

Reference:
Patent; Byk Gulden Lomberg Chemische Fabrik GmbH; US6103718; (2000); A;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Application of 2050-46-6, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 2050-46-6 name is 1,2-Diethoxybenzene, This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.

18.9 g of 1,2-diethoxybenzene obtained in Production Example 9 and 22.0 g of 3-bromobenzoyl chloride were dissolved in 100 ml dichloromethane, and 100 ml of 1.0 M tin tetrachloride in dichloromethane was added dropwise thereto under ice-cooling. After the dropwise addition, the mixture was further stirred at room temperature for 15 hours. The reaction solution was poured into ice-cold water to terminate the reaction, and the organic layer was recovered, washed with water twice and with brine, and then dried over anhydrous magnesium sulfate. The solvent was evaporated, and the crude product was recrystallized from hexane-ethyl acetate to give 23.8 g of the title compound as colorless crystals. 1H-NMR (400 MHz, CDCl3) delta 1.46-1.52 (6H, m), 4.13-4.21 (4H, m), 6.89 (1H, d, J=8.8 Hz), 7.32 (1H, dd, J=8.8,2.0 Hz), 7.35 (1H, t, J=7.8 Hz), 7.46 (1H, d, J=2.0 Hz), 7.64-7.71 (2H, m), 7.88 (1H, t, J=l.6 Hz).

At the same time, in my other blogs, there are other synthetic methods of this type of compound, 1,2-Diethoxybenzene, and friends who are interested can also refer to it.