Category: 1836-62-0

Synthetic Route of 1836-62-0,Some common heterocyclic compound, 1836-62-0, name is 2-(2-Methoxyphenoxy)ethylamine, molecular formula is C9H13NO2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

A mixture of 9.7 g 4-(OXIRANE-2-YLMETHOXY)-9H-CARBAZOLE (II), 53.7 g of anhydrous hydrogen sulphate of 2-(2-METHOXYPHENOXY) ETHYLAMINE (III) and 28 g of anhydrous potassium carbonate in 200 ML ISOPROPANOL are, with intensive stirring, heated at 80 C for six hours. When the epoxide has reacted, the mixed salts are filtered off from the reaction mixture and isopropanol is distilled off from the filtrate. The obtained honey-like concentrate is diluted with heating in 50 ml of ethylacetate, the solution is cooled to the temperature of 40 C, it is inoculated and stirred at the temperature of 40 C for two hours. After the crystal precipitates, the mixture is cooled to the temperature of 0 C, and is kept like that with stirring for a minimum of four hours. After filtration and washing with cooled ethylacetate, 5.2 g of wet, crude Carvedilol is obtained (HPLC contents 95.2 area %, HPLC contents of the bis-derivative 2.8 area %).

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 2-(2-Methoxyphenoxy)ethylamine, its application will become more common.

Reference:
Patent; Zentiva, A.S.; WO2004/41783; (2004); A1;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Synthetic Route of 1836-62-0,Some common heterocyclic compound, 1836-62-0, name is 2-(2-Methoxyphenoxy)ethylamine, molecular formula is C9H13NO2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

A mixture of 9.7 g 4-(OXIRANE-2-YLMETHOXY)-9H-CARBAZOLE (II), 53.7 g of anhydrous hydrogen sulphate of 2-(2-METHOXYPHENOXY) ETHYLAMINE (III) and 28 g of anhydrous potassium carbonate in 200 ML ISOPROPANOL are, with intensive stirring, heated at 80 C for six hours. When the epoxide has reacted, the mixed salts are filtered off from the reaction mixture and isopropanol is distilled off from the filtrate. The obtained honey-like concentrate is diluted with heating in 50 ml of ethylacetate, the solution is cooled to the temperature of 40 C, it is inoculated and stirred at the temperature of 40 C for two hours. After the crystal precipitates, the mixture is cooled to the temperature of 0 C, and is kept like that with stirring for a minimum of four hours. After filtration and washing with cooled ethylacetate, 5.2 g of wet, crude Carvedilol is obtained (HPLC contents 95.2 area %, HPLC contents of the bis-derivative 2.8 area %).

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 2-(2-Methoxyphenoxy)ethylamine, its application will become more common.

Reference:
Patent; Zentiva, A.S.; WO2004/41783; (2004); A1;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. , Recommanded Product: 2-(2-Methoxyphenoxy)ethylamine, 1836-62-0, Name is 2-(2-Methoxyphenoxy)ethylamine, molecular formula is C9H13NO2, belongs to ethers-buliding-blocks compound. In a document, author is Hao, Yanfen, introduce the new discover.

Atmospheric concentrations and temporal trends of polychlorinated biphenyls and organochlorine pesticides in the Arctic during 2011-2018

Passive air samples were deployed in Ny-Alesund and London Island (Svalbard, High Arctic) annually for seven years (2011-2018) to investigate concentrations, temporal trends and potential sources of selected persistent organic pollutants (POPs). Nine polychlorinated biphenyls and twelve organochlorine pesticides were detected in all samples, with 3,3′-dichlorobiphenyl (PCB-11) being the prevalent congener. Concentrations of most compounds were declining. The ratio of the alpha- and gamma-isomer of hexachlorocyclohexane (HCH) in Arctic air was comparable with that in technical HCH mixtures, but higher than that in the atmosphere of other countries, thereby indicating the impact of historical use as well as the possible photoisomerization of the gamma- into the alpha-isomer. The parent dichlorodiphenyltrichloroethane (DDT) was always less abundant than its degradation products dichlorodiphenylethylene (DDE), indicative of the impact of aged DDT sources in the Arctic atmosphere. However, o,p’-/p,p’-DDT ratios suggest only a minor contribution of dicofol-type DDT. A slightly declining temporal trend of the trans-chlordane/cis-chlordane ratio indicated the impact of secondary sources. The atmospheric distribution of the investigated POPs in the Arctic was mainly attributed to long-range atmospheric transport, whereas the influence of human activities from the scientific research stations was minor. (C) 2020 Elsevier Ltd. All rights reserved.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 1836-62-0. Recommanded Product: 2-(2-Methoxyphenoxy)ethylamine.

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, Computed Properties of C9H13NO2, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 1836-62-0, Name is 2-(2-Methoxyphenoxy)ethylamine, molecular formula is C9H13NO2. In an article, author is Ge, Chengbiao,once mentioned of 1836-62-0.

Facile Fabrication of Amphiphilic and Asymmetric Films with Excellent Deformability for Efficient and Stable Adsorption Applications

In this study, a facile way to prepare amphiphilic and asymmetric films with excellent mechanical properties for efficient and stable adsorption applications is reported. Non-solvent induced phase separation technology is developed to fabricate porous asymmetric poly(ether-block-amide) composite films. These films have a unique structure composed of a solid surface, a microporous surface, and hierarchical porous core, hence exhibiting prominent mechanical properties with an elongation at break up to 317% and mechanical resilience. Before and after 50-times cyclic stretching deformations, they still maintain intact porous structure, and their wetting angles of upper and lower surfaces to both water and cyclohexane are almost constant. Moreover, these films show excellent uptake for cyclohexane and water, and cyclic large deformations have little influence on the performance. It only takes 3 s to absorb 4 times of the weight of cyclohexane, while 1.8 times of water can be loaded within 134 s.

If you¡¯re interested in learning more about 1836-62-0. The above is the message from the blog manager. Computed Properties of C9H13NO2.

Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 1836-62-0, Name is 2-(2-Methoxyphenoxy)ethylamine, molecular formula is C9H13NO2, belongs to ethers-buliding-blocks compound, is a common compound. In a patnet, author is Luo, Chaodi, once mentioned the new application about 1836-62-0, Product Details of 1836-62-0.

Pharmacological corrections of the mutant hERG channels by posaconazole

Properties of mutant human ether-a-go-go-related gene (hERG) channels can be modified by some antibiotics. However, the pharmacological effects of posaconazole on cardiomyocyte hERG channels remain unclear. Whole-cell patch clamping, western blotting and laser confocal scanning microscopy were used to evaluate the effects of posaconazole on wild-type (WT)-, A561V- and L539 fs/47-hERG channels expressed in human embryonic kidney (HEK) 293 cells. In electrophysiological experiments, HEK 293 cells were transiently co-transfected with equal amounts of WT-hERG, WT+A561 V-hERG and WT+L539 fs/47-hERG plasmids to mimic a heterozygous genotype. Posaconazole (30 mu M) increased tail currents in cells expressing WT-hERG, WT+A561 V-hERG and WT+L539 fs/47-hERG by 82.65%, 147.72% and 134.73%, respectively, compared to controls. Posaconazole increased hERG protein expression in cells expressing WT-hERG, WT+A561 V-hERG and WT+L539 fs/47-hERG compared to controls condition as well as their trafficking to the cell membrane. To our knowledge, this is the first study to show that antifungal agent posaconazole rescues the mutant A561 V-hERG and L539 fs/47-hERG channels by altering the gating kinetics, enhancing the expression and trafficking of hERG channels. The results demonstrate that posaconazole could be a promising candidate for the prevention and treatment of long QT syndrome and other arrhythmia-related diseases.

We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 1836-62-0. The above is the message from the blog manager. Product Details of 1836-62-0.

Related Products of 1836-62-0, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C¨CH bond functionalisation has revolutionised modern synthetic chemistry. 1836-62-0, Name is 2-(2-Methoxyphenoxy)ethylamine, SMILES is COC1=CC=CC=C1OCCN, belongs to ethers-buliding-blocks compound. In a article, author is Rataczak, Jens A., introduce new discover of the category.

Verification of quantitative infrared thermography heat-flux measurements

Stagnation-point heat flux was measured on 7 half-angle circular cones with spherical nose diameters of 5, 10, and 25 mm using infrared thermography in hypersonic flow. All models were machined from polyether ether ketone (PEEK). A nominal freestream Mach number of 6 with varying initial stagnation conditions allowed for testing at length Reynolds numbers based on nose diameter ranging from 5 x 10(4)-5 x 10(5). Fay & Riddell’s theory for calculating heat flux at the stagnation point provided a comparison to verify experimental data-reduction methods. Excellent agreement was obtained. Sources of deviation were investigated and best practices for obtaining heat-flux values most similar to theory are presented. Heat flux calculated using a one-dimensional assumption had a mean error of 8.9% from the theoretical expectation. To improve upon this, an implicit, finite-difference approximation was used to solve the axisymmetric heat equation in spherical coordinates, assuming a known surface temperature and isothermal back face. The axisymmetric calculation yielded steadystate heat-flux magnitudes 1-10% greater than the one-dimensional approach, as expected. Correcting for longitudinal heat transfer yielded heat fluxes more nearly proportional to 1/root D, and the mean error decreased to 4.8%.

Related Products of 1836-62-0, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. I hope my blog about 1836-62-0 is helpful to your research.

Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. , Name: 2-(2-Methoxyphenoxy)ethylamine, 1836-62-0, Name is 2-(2-Methoxyphenoxy)ethylamine, molecular formula is C9H13NO2, belongs to ethers-buliding-blocks compound. In a document, author is Kojcinovic, Aleksa, introduce the new discover.

Furfural hydrogenation, hydrodeoxygenation and etherification over MoO2 and MoO3: A combined experimental and theoretical study

Valorization of lignocellulosic biomass, particularly catalytic hydrotreatment of hemicellulose-based furfural (FUR), has been studied for the production of value-added chemicals. A three-phase batch reactor has been used for hydrotreatment in isopropanol over various commercially available unsupported MoOx catalysts, at various temperatures (170-230 degrees C), pressures (0-80 bar H-2), catalyst loadings (0-2 wt%), and reactant concentrations (5-20 wt%). No significant difference in catalytic activity or selectivity has been observed among the three different MoO3 and one MoO2 catalysts, while NiMo/Al2O3, Mo2C and WO3 were much less active. Data-points collected have been used to propose a detailed reaction pathway network for a micro-kinetic model, which also took into consideration the thermodynamics, and adsorption, desorption, and surface reaction kinetics. The alcoholysis of FUR yielded valuable isopropyl levulinate (IPL) as the major product under all tested reaction conditions, while other value-added compounds (furfuryl alcohol, isopropyl furfuryl ether, furfuryl acetone, angelica lactone) were observed in smaller quantities. It was found that neither the presence nor the absence of the gaseous H-2 pressure contributes to the global reaction rate, or selectivity, since the solvent acts as a sufficient hydrogen donor. Additionally, density functional theory (DFT) calculations provided further insight into the active planes present by the implementation of the Wulff construction. Furthermore, the reaction mechanism was explained based on reaction energies, which were in silico determined and compared for several surfaces. The results were consistent with the characterization and activity-testing results. The furfural ring-opening reaction, yielding valuable IPL in the absence of gaseous H-2, over a cheap bulk MoOx is reported for the first time.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 1836-62-0. Name: 2-(2-Methoxyphenoxy)ethylamine.

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 1836-62-0, Name is 2-(2-Methoxyphenoxy)ethylamine, molecular formula is C9H13NO2. In an article, author is Zhang, Zhen,once mentioned of 1836-62-0, COA of Formula: C9H13NO2.

Understanding H2O2-Induced Thermo-Oxidative Reclamation of Vulcanized Styrene Butadiene Rubber at Low Temperatures

Recombination reactions often occur in the process of chemical, thermal, or mechanical degradation of vulcanized styrene butadiene rubber (SBR), which hinders the recycling efficiency of waste tire rubbers. In this work, we developed an effective method to transform solid vulcanized SBR into reclaimed rubber with 100% sol fraction through a hydrogen peroxide (H2O2)-induced thermo-oxidative reclamation process at 100 degrees C with the assistance of soybean oil. The structural evolution of the vulcanized SBR and the role of H2O2 and soybean oil in the reclaiming process were investigated by sol-gel analysis, gel permeation chromatography (GPC), attenuated total reflectance-Fourier transform infrared spectroscopy (ATR-FTIR), and C-13 nuclear magnetic resonance (C-13 NMR) spectroscopy. The results showed that vulcanized SBR underwent severe oxidative scission, the sol of the reclaimed samples increased from 20.4 wt % up to 100 wt % with a decreased molecular weight to 1.378 x 10(4) g/mol. Multiple functional groups such as carboxyl, hydroxyl, and ether groups were generated in the polymer chains as confirmed by C-13 NMR and FTIR spectroscopy. Moreover, the reaction pathway of the oxidative reclamation was quantified by density functional theory (DFT) calculations, suggesting that hydroxyl radicals were generated from a homolytic cleavage reaction of H2O2 with SBR by hydrogen abstraction and accelerated the rate-determining step of the SBR oxidation. The apparent activation energy (E-a) of the initial stage of the oxidative reclamation decreased from 223 to 160 kJ/mol according to the model-free kinetics results.

Interested yet? Keep reading other articles of 1836-62-0, you can contact me at any time and look forward to more communication. COA of Formula: C9H13NO2.

Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 1836-62-0, Name is 2-(2-Methoxyphenoxy)ethylamine, SMILES is COC1=CC=CC=C1OCCN, belongs to ethers-buliding-blocks compound. In a document, author is Li, Cong, introduce the new discover, Application In Synthesis of 2-(2-Methoxyphenoxy)ethylamine.

A fluorescence strategy for monitoring alpha-glucosidase activity and screening its inhibitors from Chinese herbal medicines based on Cu nanoclusters with aggregation-induced emission

Herein, the self-assembly of 1-dodecanethiol-capped Cu nanoclusters (DT-Cu NCs) is obtained by annealing of dibenzyl ether solution of nanoclusters. These aggregates are composed of small clusters and emit a high level of aggregation-induced emission (AIE) in water. Based on the quenching effect of 4-nitrophenol (4-NP) on DT-Cu NCs, a fluorescence strategy is developed to monitor alpha-glucosidase (alpha-Glu) activity and screen its inhibitors from Chinese herbal medicines. 4-Nitrophenyl-alpha-D-glucopyranoside (NGP) is selected as the substrate, which is further hydrolyzed to yield 4-NP through the catalysis of alpha-Glu. The quenching efficiency is positively correlated to the concentration of alpha-Glu. Furthermore, the inhibitory effects of the extracts from four Chinese herbal medicines (i.e., the rind of Punica granatum L., Momordica grosvenorii Swingle., Crataegus pinnatifida Bge., and Lycium barbarum L.) on the alpha-Glu activity have been studied. The IC50 values of extracts from the rind of Punica granatum L. and Momordica grosvenorii Swingle are 0.23 and 0.37 g/L, respectively, so they show obvious inhibitory effects on alpha-Glu. The extracts of Crataegus pinnatifida Bge. and Lycium barbarum L. exhibit relatively weak inhibitory effects. Hence, the proposed strategy can be applicable for screening alpha-Glu inhibitors from Chinese herbal medicines. Last but not the least, by immobilizing DT-Cu NCs into agarose hydrogels in polyethylene tubes, a visual device is fabricated to screen alpha-Glu inhibitors with high throughput and sensitivity.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 1836-62-0 is helpful to your research. Application In Synthesis of 2-(2-Methoxyphenoxy)ethylamine.

In an article, author is Yao, Bin, once mentioned the application of 1836-62-0, Name is 2-(2-Methoxyphenoxy)ethylamine, molecular formula is C9H13NO2, molecular weight is 167.205, MDL number is MFCD00235185, category is ethers-buliding-blocks. Now introduce a scientific discovery about this category, Formula: C9H13NO2.

Current progress in degradation and removal methods of polybrominated diphenyl ethers from water and soil: A review

The widespread of polybrominated diphenyl ethers (PBDEs) in the environment has caused rising concerns, and it is an urgent endeavor to find a proper way for PBDEs remediation. Various techniques such as adsorption, hydrothermal and thermal treatment, photolysis, photocatalytic degradation, reductive debromination, advanced oxidation processes (AOPs) and biological degradation have been developed for PBDEs decontamination. A comprehensive review of different PBDEs remediation techniques is urgently needed. This work focused on the environmental source and occurrence of PBDEs, their removal and degradation methods from water and soil, and prospects for PBDEs remediation techniques. According to the up-to-date literature obtained from Web of Science, it could be concluded that (i) photocatalysis and photocatalytic degradation is the most widely reported method for PBDEs remediation, (ii) BDE-47 and BDE-209 are the most investigated PBDE congeners, (iii) considering the recalcitrance nature of PBDEs and more toxic intermediates could be generated because of incomplete degradation, the combination of different techniques is the most potential solution for PBDEs removal, (iv) further researches about the development of novel and effective PBDEs remediation techniques are still needed. This review provides the latest knowledge on PBDEs remediation techniques, as well as future research needs according to the up-to-date literature.

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