Related Products of 1682-04-8, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 1682-04-8, name is 1-Bromo-2,3,5,6-tetrafluoro-4-methoxybenzene, This compound has unique chemical properties. The synthetic route is as follows.
To a 200 mL flask which had been sufficiently dried under argon atmosphere, 30 mL of anhydrous pentane and 25.9 g (0.10 mol) of 4-bromo-2,3,5,6-tetrafluoroanisole were added and the mixture was cooled to -78 C. in a dry ice/acetone bath. Dropped thereto over 50 minutes was 61.2 mL of 1.6 mol/L n-butyl lithium hexane solution and the thus obtained mixture was subsequently stirred for 5 hours at -78 C. Thereto dropped over 30 minutes was 24.5 mL of 1 mol/L boron trichloride/hexane solution. The thus obtained reaction solution was stirred while being restored to room temperature, followed by further stirring for 12 hours after the reaction solution was restored to room temperature. To this reaction solution, 80 mL of water was slowly added to hydrolyze the reaction mixture and the formed crystals were collected, which were then washed with 80 mL of hexane and 80 mL of water to obtain 12.2 g of tetrakis(2,3,5,6-tetrafluoro-4-methoxyphenyl) lithium borate having an HPLC purity of 98.1% (Yield: 68%). The thus obtained product was subjected to measurements by 1H-NMR (heavy methanol solvent) and MALDI TOF-MS to confirm that it was the desired product.(0180)(Measurement Results)(0181)1H-NMR (shift; ppm: multiplicity: number of protons)(0182)(3.8: s: 12)(0183)MALDI TOF-MS (m/z)(0184)mass: 727.21 (Theoretical value: 727.19)
The chemical industry reduces the impact on the environment during synthesis 1-Bromo-2,3,5,6-tetrafluoro-4-methoxybenzene. I believe this compound will play a more active role in future production and life.