Category: 157869-15-3

On June 30, 2017, Sinai, Adam; Meszaros, Adam; Balogh, Adam; Zwillinger, Marton; Novak, Zoltan published an article.Product Details of 157869-15-3 The title of the article was Hexafluorosilicic Acid as a Novel Reagent for the Desilylation of Silylacetylenes: Application in Sequential Sonogashira Coupling and Click Reaction. And the article contained the following:

Hexafluorosilicic acid was utilized as a novel, cheap, readily available, and environmentally benign alternative reagent for the desilylation of 1-trimethylsilylacetylenes. The applicability of the aqueous solution of the hexafluorosilicic acid was demonstrated in the sequential coupling of aryl halides and ethynyltrimethylsilane to afford internal acetylenes, benzofurans, and triazoles in one-pot Sonogashira-Sonogashira and Sonogashira-CuAAC reactions. The experimental process involved the reaction of 2-((4-Methoxyphenyl)ethynyl)aniline(cas: 157869-15-3).Product Details of 157869-15-3

The Article related to arylalkyne preparation, aryl iodide silylacetylene sequential sonogashira coupling click chem, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Hydrocarbons (Saturated and Unsaturated Side Chains) and other aspects.Product Details of 157869-15-3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Tang, Lin; Wu, Chaoting; Hu, Qiyan; Li, Qian; Zhang, Wu published an article in 2018, the title of the article was Cross-coupling reactions using porous multipod Cu2O microcrystals as recoverable catalyst in aqueous media.Related Products of 157869-15-3 And the article contains the following content:

Porous multipod Cu2O microcrystals were found to be an efficient, highly recyclable and eco-friendly catalyst for the cross-coupling reactions of aryl halides and terminal alkynes with high yields in aqueous media. Noteworthy, the Cu2O catalyst can be reused for several times without significant decrease in catalytic activity. The experimental process involved the reaction of 2-((4-Methoxyphenyl)ethynyl)aniline(cas: 157869-15-3).Related Products of 157869-15-3

The Article related to aryl halide alkyne terminal copper sonogashira coupling catalyst, alkyne aryl preparation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Hydrocarbons (Saturated and Unsaturated Side Chains) and other aspects.Related Products of 157869-15-3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On November 2, 2018, Ouyang, Xuan-Hui; Tan, Fang-Lin; Song, Ren-Jie; Deng, Wei; Li, Jin-Heng published an article.Recommanded Product: 2-((4-Methoxyphenyl)ethynyl)aniline The title of the article was Palladium-Catalyzed Oxidative [2 + 2 + 1] Annulation of 1,7-Diynes with H2O: Entry to Furo[3,4-c]quinolin-4(5H)-ones. And the article contained the following:

A novel cascade annulation of 1,7-diynes I [R2 = R3 = Ph, R4 = H, Y = NBn; R2 = R3 = Ph, R4 = H, Y = O; R2 = Ph, 4-MeOC6H4, 4-BrC6H4, 2-thiophenyl, cyclopropyl, R3 = Ph, 4-MeOC6H4, 4-ClC6H4 R4 = H, Y = NMe; R2 = Ph, R3 = Ph, R4 = Me, Cl, Y = NMe] with water has been developed for the synthesis of furo[3,4-c]quinolin-4(5H)-one skeletons II with high atom- and step-economy. The transformation was enabled by a palladium catalyst in the presence of copper salt as the promoter, involving the formation of one C-C bond and two C-O bonds. Moreover, the reaction exhibits good tolerance of functional groups and broad substrate scope. Notably, the control experiments support the incorporation of the new oxygen atom from water. The experimental process involved the reaction of 2-((4-Methoxyphenyl)ethynyl)aniline(cas: 157869-15-3).Recommanded Product: 2-((4-Methoxyphenyl)ethynyl)aniline

The Article related to preparation furoquinolinone palladium catalyzed cascade oxidative annulation diyne water, Heterocyclic Compounds (More Than One Hetero Atom): Fused-Ring Systems With Two Or More Hetero Atoms, No More Than One Hetero Atom Per Ring and other aspects.Recommanded Product: 2-((4-Methoxyphenyl)ethynyl)aniline

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Dagar, Anuradha; Guin, Soumitra; Samanta, Sampak published an article in 2018, the title of the article was AgSbF6-Catalyzed Tandem Reaction of 2-Alkynylanilines with Cyclic Enynones: Efficient access to 3-Furo[3,2-c]chromenylindoles and Related Scaffolds.Application In Synthesis of 2-((4-Methoxyphenyl)ethynyl)aniline And the article contains the following content:

A simple, mild, catalytic and efficient method for the straightforward synthesis of an interesting class of a range of 2-aryl/alkyl-substituted-3-(2-aryl/alkyl-4H-furo[3,2-c]chromen-4-yl)-1H-indoles I [R = H, Bn; R1 = C6H5, (CH2)3CH3, 4-CH3C6H4, etc.; R2 = C6H5, (CH2)3CH3, 4-CH3C6H4, etc.; X = H, F, OCH3; Y = H, F, CH3, OCH3] in good to high yields is reported for the first time. This atom-efficient method proceeds via AgSbF6-catalyzed one-pot sequential intramol. hydroamination (C-N bond formation) of 2-alkynylanilines 5-X-2-R1CCC6H3NHR followed by Friedel-Crafts alkylation/oxa-cyclization (creation of new C-C and C-O bonds) reaction between in situ generated 2-substituted indoles and several cyclic enynones II and 2-(phenylethynyl)cyclohex-2-enone. The experimental process involved the reaction of 2-((4-Methoxyphenyl)ethynyl)aniline(cas: 157869-15-3).Application In Synthesis of 2-((4-Methoxyphenyl)ethynyl)aniline

The Article related to furochromenylindole preparation, alkynylaniline enynone heterocyclization silver catalyst, Heterocyclic Compounds (More Than One Hetero Atom): Fused-Ring Systems With Two Or More Hetero Atoms, No More Than One Hetero Atom Per Ring and other aspects.Application In Synthesis of 2-((4-Methoxyphenyl)ethynyl)aniline

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Liu, Rui-Juan; Wang, Peng-Fei; Yuan, Wen-Kui; Wen, Li-Rong; Li, Ming published an article in 2017, the title of the article was Nickel Catalysis Enables Hetero [2+2+1] Cycloaddition between Yne-Isothiocyanates and Isonitriles with Low Catalyst Loading.Electric Literature of 157869-15-3 And the article contains the following content:

Nickel(II) can be used to catalyze the hetero [2+2+1] cycloaddition of 2-alkynylaryl isothiocyanates and isonitriles in 2-methyltetrahydrofuran (2-MeTHF) to give a wide array of thieno[2,3-b]indoles in excellent yields. The reaction is featured by employing as little as 0.3 mol% nickel(II) acetylacetonate [Ni(acac)2] under air conditions in the absence of any additives (addnl. reducing agents and external ligands). This is the first successful example to apply nickel(II) directly in hetero [2+2+1] cycloadditions The experimental process involved the reaction of 2-((4-Methoxyphenyl)ethynyl)aniline(cas: 157869-15-3).Electric Literature of 157869-15-3

The Article related to alkynylaryl isothiocyanate isonitrile nickel hetero cycloaddition catalyst, thienoindole preparation, Heterocyclic Compounds (More Than One Hetero Atom): Fused-Ring Systems With Two Or More Hetero Atoms, No More Than One Hetero Atom Per Ring and other aspects.Electric Literature of 157869-15-3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Gao, Qian; Zhou, Peng; Liu, Feng; Hao, Wen-Juan; Yao, Changsheng; Jiang, Bo; Tu, Shu-Jiang published an article in 2015, the title of the article was Cobalt(II)/silver relay catalytic isocyanide insertion/cycloaddition cascades: a new access to pyrrolo[2,3-b]indoles.Recommanded Product: 2-((4-Methoxyphenyl)ethynyl)aniline And the article contains the following content:

The combination of Co(acac)2 and AgOTf enables the bimetallic relay catalysis reaction of 2-ethynylanilines and isocyanides, allowing easy and low-cost access to new densely functionalized pyrrolo[2,3-b]indoles. The reaction pathway involves a Co(acac)2-catalyzed double isocyanide insertion followed by a silver-enabled 1,3-dipolar cycloaddition [e.g., 2-(phenylethynyl)aniline + isocyanocyclohexane in 1:2 molar ratio → pyrrolo[2,3-b]indole I (up to 86%, under aerobic conditions)]. The synthetic utility of these bicycloaddn. reactions results in subsequent C-C and C-N bond-forming events to rapidly build up mol. complexity. The experimental process involved the reaction of 2-((4-Methoxyphenyl)ethynyl)aniline(cas: 157869-15-3).Recommanded Product: 2-((4-Methoxyphenyl)ethynyl)aniline

The Article related to cobalt silver relay catalytic isocyanide insertion cycloaddition cascade, ethynylanaline reaction isocyanide pyrroloindole preparation, Heterocyclic Compounds (More Than One Hetero Atom): Fused-Ring Systems With Two Or More Hetero Atoms, No More Than One Hetero Atom Per Ring and other aspects.Recommanded Product: 2-((4-Methoxyphenyl)ethynyl)aniline

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On October 19, 2016, Hao, Wen-Juan; Wu, Ya-Nan; Gao, Qian; Wang, Shu-Liang; Tu, Shu-Jiang; Jiang, Bo published an article.Recommanded Product: 157869-15-3 The title of the article was Dual cobalt(II)/silver catalysis: synthesis of aryliminated pyrrolo[2,3-b]indoles via multicomponent bicyclization cascades. And the article contained the following:

Dual cobalt(II)/silver catalysis enables multicomponent bicyclization cascades of 2-ethynylanilines, tert-Bu isocyanide, and arylamines, resulting in subsequent multiple bond-forming events to rapidly build up aryliminated pyrrolo[2,3-b]indoles such as I. The reaction pathway involves bimetal-catalyzed isocyanide insertion/1,3-dipolar cycloaddition/imination substitution sequence. The experimental process involved the reaction of 2-((4-Methoxyphenyl)ethynyl)aniline(cas: 157869-15-3).Recommanded Product: 157869-15-3

The Article related to aryliminated pyrroloindole preparation, ethynylaniline tert bu isocyanide arylamine multicomponent bicyclization cascade, cobalt silver catalyst, Heterocyclic Compounds (More Than One Hetero Atom): Fused-Ring Systems With Two Or More Hetero Atoms, No More Than One Hetero Atom Per Ring and other aspects.Recommanded Product: 157869-15-3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On September 1, 2017, Li, Jie; Zhang, Wen-Wen; Wei, Xiao-Jing; Hao, Wen-Juan; Li, Guigen; Tu, Shu-Jiang; Jiang, Bo published an article.Application In Synthesis of 2-((4-Methoxyphenyl)ethynyl)aniline The title of the article was Synthesis of Tribenzo[b,e,g]phosphindole Oxides via Radical Bicyclization Cascades of o-Arylalkynylanilines. And the article contained the following:

A new DTBP/Mg(NO3)2-mediated bicyclization cascade of o-arylalkynylanilines with secondary arylphosphine oxides was developed, enabling dual C(sp2)-H functionalization along with the cleavage of the C-N bond. The combination between regioselective P-centered radical-triggered [3 + 2] cyclization and C-centered radical-induced cross-coupling in a 1-pot manner delivered 27 examples of tribenzo[b,e,g]phosphindole oxides with generally high regioselectivity. A reasonable mechanism for forming such products involving radical addition-cyclization cascade is proposed. The experimental process involved the reaction of 2-((4-Methoxyphenyl)ethynyl)aniline(cas: 157869-15-3).Application In Synthesis of 2-((4-Methoxyphenyl)ethynyl)aniline

The Article related to alkynylaniline radical triggered bicyclization cascade phosphine oxide, tribenzophosphindole oxide preparation crystal structure, mol structure tribenzophosphindole oxide and other aspects.Application In Synthesis of 2-((4-Methoxyphenyl)ethynyl)aniline

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On June 21, 2019, Tao, Shou-Wei; Zhou, Jing-Ya; Liu, Rui-Qing; Zhu, Yong-Ming published an article.Quality Control of 2-((4-Methoxyphenyl)ethynyl)aniline The title of the article was One-Pot Synthesis of N-Imidoyl-(1H)-indoles via Palladium-Catalyzed Oxidative Insertion Domino Reaction with Isocyanide and Arylboronic Acid. And the article contained the following:

Efficient one-pot synthesis of N-imidoyl-1H-indoles, e.g., I, has been described, which is achieved by the palladium-catalyzed oxidative insertion of 2-(phenylethynyl)aniline, arylboronic acid, and isonitrile. This method provides a way to synthesize N-imidoyl-(1H)-indoles, which has a wide substrate scope, good functional group tolerance, and mild reaction condition. The experimental process involved the reaction of 2-((4-Methoxyphenyl)ethynyl)aniline(cas: 157869-15-3).Quality Control of 2-((4-Methoxyphenyl)ethynyl)aniline

The Article related to alkynylaniline arylboronic acid isocyanide oxidative insertion domino reaction palladium, imidoylindole preparation, palladium oxidative insertion domino reaction catalyst and other aspects.Quality Control of 2-((4-Methoxyphenyl)ethynyl)aniline

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Liu, Wei; Liu, Sheng; Xie, Hongqi; Qing, Zhixing; Zeng, Jianguo; Cheng, Pi published an article in 2015, the title of the article was TBHP mediated oxidation of N-2-alkynylphenyl α-amino carbonyl compounds to oxalic amides using visible light photoredox catalysis and their application in the synthesis of 2-aryl indoles.Application In Synthesis of 2-((4-Methoxyphenyl)ethynyl)aniline And the article contains the following content:

A visible light promoted and TBHP mediated oxidative reaction of N-((2-arylalkynyl)aryl)glycine esters I [R1 = H, 4-Me, 4-F, 4-Cl; R2 = C6H5, Pr, 2-F-C6H4, etc.] to give (2-arylalkynyl)oxalic amides II was developed. In the presence of CuBr and photocatalyst Ru(bpy)3Cl2, the reaction proceeded smoothly to afford the corresponding oxalic amides under the irradiation of 26 W compact fluorescence bulb at room temperature Furthermore, compounds II were further reacted to give 2-aryl indoles III [R1 = H, 5-F; R3 = H, 4-Me, 2-F, 4-F] without an addnl. deacylation step through a favored 5-endo-dig N-cyclization process using AgNO3 as catalyst. The experimental process involved the reaction of 2-((4-Methoxyphenyl)ethynyl)aniline(cas: 157869-15-3).Application In Synthesis of 2-((4-Methoxyphenyl)ethynyl)aniline

The Article related to aryl indole preparation, arylalkynyl oxalic amide preparation silver nitrate catalyst cyclization, tbhp oxidant arylalkynyl glycine ester ruthenium photocatalyst oxidation and other aspects.Application In Synthesis of 2-((4-Methoxyphenyl)ethynyl)aniline

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem