Category: 150-19-6

Dong, Zhenhua; Pan, Hongguo; Liu, Mengmeng published an article in 2021. The article was titled 《Catalyst-free rapid conversion of arylboronic acids to phenols under green condition》, and you may find the article in ARKIVOC (Gainesville, FL, United States).HPLC of Formula: 150-19-6 The information in the text is summarized as follows:

A catalyst-free and solvent-free method for the oxidative hydroxylation of aryl boronic acids to corresponding phenols with hydrogen peroxide as the oxidizing agent was developed. The reactions could be performed under green condition at room temperature within very short reaction time. 99% yield of phenol could be achieved in only 1 min. A series of different arenes substituted aryl boronic acids were further carried out in the hydroxylation reaction with excellent yield. It was worth nothing that the reaction could completed within 1 min in all cases in the presence of ethanol as co-solvent. In the experiment, the researchers used many compounds, for example, m-Methoxyphenol(cas: 150-19-6HPLC of Formula: 150-19-6)

m-Methoxyphenol(cas: 150-19-6) may be used as an analytical standard for the determination of the analyte in wine, coffee beans, wood samples, and mainstream smoke by gas chromatography (GC) based techniques.HPLC of Formula: 150-19-6

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Ether – Wikipedia,
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《Synthesis of 4-trifluoromethyl-2H-chromenes via the reaction of 2-(trifluoroacetyl)phenols with vinyltriphenylphosphonium chloride》 was written by Golubev, Alexander S.; Ostapchuk, Petr N.; Strelkova, Tatiana V.; Kagramanov, Nikolai D.; Suponitsky, Kyrill Yu.; Takazova, Rina U.; Chkanikov, Nikolai D.. Category: ethers-buliding-blocksThis research focused ontrifluoroacetyl phenol vinyltriphenylphosphonium chloride Schweizer reaction; trifluoromethyl chromene preparation. The article conveys some information:

Substituted on the benzene ring 4-CF3-2H-chromenes were prepared from substituted 2-(trifluoroacetyl)phenols and vinyltriphenylphosphonium chloride according to the Schweizer protocol in moderate to excellent yields. The influence of the type and the position of aromatic ring substituents on yields of 4-CF3-2H-chromenes were investigated. It was shown that 4-CF3-2H-chromenes were convenient precursors to 4-CF3-coumarins. The results came from multiple reactions, including the reaction of m-Methoxyphenol(cas: 150-19-6Category: ethers-buliding-blocks)

m-Methoxyphenol(cas: 150-19-6) may be used as an analytical standard for the determination of the analyte in wine, coffee beans, wood samples, and mainstream smoke by gas chromatography (GC) based techniques.Category: ethers-buliding-blocks

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Ether – Wikipedia,
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《MnSb2O6-chitosan nanocomposite: An efficient catalyst for the synthesis of coumarins via Pechmann reaction》 was published in Journal of Heterocyclic Chemistry in 2020. These research results belong to Bahramnezhad, Baharak; Ghazanfari, Dadkhoda; Sheikhhosseini, Enayatollah; Akhgar, Mohammad Reza; Ahmadi, Sayed Ali. HPLC of Formula: 150-19-6 The article mentions the following:

In this work, MnSb2O6-chitosan nanocomposites were synthesized and have been employed in Pechmann condensation for the synthesis of coumarin derivatives e.g., I. MnSb2O6-chitosan nanocomposites were characterized by Fourier transform IR (FTIR), X-ray powder diffraction (XRD), scanning electron microscope (SEM), and energy-dispersive X-ray spectroscopy (EDX) techniques. The particles of MnSb2O6-chitosan have uniform spheres with sizes that are less than 100 nm. Simplicity, easy work-up, and short reaction times are advantages of this reaction. Also, the antibacterial activity for some of the products was evaluated, and the result showed significant pharmaceutical activities as antibacterial reagents against Staphylococcus aureus and Escherichia coli. In the experiment, the researchers used m-Methoxyphenol(cas: 150-19-6HPLC of Formula: 150-19-6)

m-Methoxyphenol(cas: 150-19-6) may be used in synthesis of:C(4) symmetric calix[4]resorcinarene, 2-nitroso-5-methoxyphenol, 6-methoxy-2(3H)-benzoxazoloneHPLC of Formula: 150-19-6

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Ether – Wikipedia,
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《Development of a Robust Protocol for the Synthesis of 6-Hydroxybenzofuran-3-carboxylic Acid》 was written by Gallou, Isabelle; Erb, Bernhard; Marti, Michael; Nuzzo, Gian-Luca; Jager, Andreas; Seeger, Manuela; Chassagne, Pierre; Aronow, Jonas; Cortes-Clerget, Margery; Gallou, Fabrice. Recommanded Product: m-Methoxyphenol And the article was included in Organic Process Research & Development in 2020. The article conveys some information:

Benzofuran scaffolds are fundamental moieties found in a variety of biol. active natural products and synthetic drugs. In the course of one of our development programs, we needed to develop a practical and cost-effective manufacturing approach to such a benzofuran scaffold. Here we report a highly robust four-step, one-pot process that provides access to a 6-hydroxybenzofuran-3-carboxylic acid structure. An 1H NMR monitoring study allowed a better understanding of the overall sequence of events and the nature of the detected intermediates. After six steps, including the optimized tandem process, the desired hydroxylated benzofuran was obtained in 40% yield with a purity above 99%. In the experimental materials used by the author, we found m-Methoxyphenol(cas: 150-19-6Recommanded Product: m-Methoxyphenol)

m-Methoxyphenol(cas: 150-19-6) may be used in synthesis of:C(4) symmetric calix[4]resorcinarene, 2-nitroso-5-methoxyphenol, 6-methoxy-2(3H)-benzoxazoloneRecommanded Product: m-Methoxyphenol

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

De Smet, Gilles; Bai, Xingfeng; Mensch, Carl; Sergeyev, Sergey; Evano, Gwilherm; Maes, Bert U. W. published an article in 2022. The article was titled 《Selective Nickel-Catalyzed Hydrodeacetoxylation of Aryl Acetates》, and you may find the article in Angewandte Chemie, International Edition.Recommanded Product: m-Methoxyphenol The information in the text is summarized as follows:

Ni-catalyzed hydrodeacetoxylation of aryl acetates (Ar-OAc) with HBpin in a green carbonate solvent selectively delivered the corresponding deoxygenated arenes (ArH). The method was also applicable to highly challenging guaiacyl and syringyl acetates, leaving -OMe groups intact without arene reduction Renewable 4-propylguaiacol obtained from pine could also be transformed without significant loss in yield vs. oil derived feedstock. The observed chemoselectivity for Ar-OAc vs. ArO-Ac bond cleavage was rationalized based on mechanistic experiments and DFT calculations ArOH side-product formation was attributed to direct competitive Ni-catalyzed reduction of the C=O bond. Hydrodeacyloxylation of a set of aryl alkanoates featured interesting chemoselectivity with a dramatic influence of the length and structure of the alkyl chain on catalysis. After reading the article, we found that the author used m-Methoxyphenol(cas: 150-19-6Recommanded Product: m-Methoxyphenol)

m-Methoxyphenol(cas: 150-19-6) may be used in synthesis of:C(4) symmetric calix[4]resorcinarene, 2-nitroso-5-methoxyphenol, 6-methoxy-2(3H)-benzoxazoloneRecommanded Product: m-Methoxyphenol

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Ether – Wikipedia,
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《A click chemistry approach for the synthesis of cyclic ureido tethered coumarinyl and 1-aza coumarinyl 1,2,3-triazoles as inhibitors of Mycobacterium tuberculosis H37Rv and their in silico studies》 was written by Khanapurmath, Netravati; Kulkarni, Manohar V.; Joshi, Shrinivas D.; Anil Kumar, G. N.. Application of 150-19-6This research focused ontriazole preparation SAR mol docking antitubercular activity; 4-(Azidomethyl)-2H-chromen-2-ones/quinolin-2(1H)-ones; Click triazole; Mycobacterium tuberculosis H37Rv; Surflex-Dock algorithm. The article conveys some information:

Nucleoside bases like uracil, pharmacophoric triazoles and benzimidazolones have been used during the present study to design mol. matrixes for antitubercular activity, employing Click Chem. Click triazoles I (R = H, 6-Me, 6-OMe, 5,7-di-Me; X = O, NH), II (R = H, 6-Me, 6-OMe, 7-Me, 5,7-di-Me; X = O, NH), and III (R = H, 7-OMe, 6-Cl, 8-Me, etc.; X = O, NH) have been obtained by the reaction of 4-(azidomethyl)-2H-chromen-2-ones/quinolin-2(1H)-ones and propargyl ethers derived from theophylline/6-Me uracil/2-benzimidazolone resp. In addition to spectral data structures have been confirmed by single crystal X-ray diffraction studies in case of 6-methyl-1,3-di-prop-2-ynyl-1H-pyrimidine-2,4-dione and theophylline mono triazole I (R = 5,7-dimethyl). Theophylline linked mono triazoles, I and 6-Me uracil linked bis triazoles, II have been found to inhibit Mycobacterium tuberculosis H37Rv with MIC values in the range 55.62-115.62μM. Benzimidazolone bis triazoles, III showed better activity with MIC in the range 2.33-18.34μM. Mol. modeling studies using Surflex-Dock algorithm supported the results. In addition to this study using m-Methoxyphenol, there are many other studies that have used m-Methoxyphenol(cas: 150-19-6Application of 150-19-6) was used in this study.

m-Methoxyphenol(cas: 150-19-6) may be used as an analytical standard for the determination of the analyte in wine, coffee beans, wood samples, and mainstream smoke by gas chromatography (GC) based techniques.Application of 150-19-6

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2022,Mohammed, Ehtesham U. R.; Porter, Zoe J.; Jennings, Ian G.; Al-Rawi, Jasim M. A.; Thompson, Philip E.; Angove, Michael J. published an article in Bioorganic & Medicinal Chemistry. The title of the article was 《Synthesis and biological evaluation of 4H-benzo[e][1,3]oxazin-4-ones analogues of TGX-221 as inhibitors of PI3Kβ》.Quality Control of m-Methoxyphenol The author mentioned the following in the article:

A novel series of TGX-221 analogs was prepared that include isosteric replacement of the 4H-pyrido[1,2-a]pyrimidin-4-one with a 4H-benzo[e][1,3]oxazin-4-one I (R = Ph, 3,5-F2C6H3, 3-ClC6H4, etc.; X = O, NH) scaffold. The compounds that included an -CH(CH3)NH- type linker showed comparable activity to TGX-221 analogs with the isosterism supported by the comparative SAR anal. The analogs containing an -CH(CH3)O- linker were less active but still showed useful SAR including a favored o-Me substitution. The experimental part of the paper was very detailed, including the reaction process of m-Methoxyphenol(cas: 150-19-6Quality Control of m-Methoxyphenol)

m-Methoxyphenol(cas: 150-19-6) may be used in synthesis of:C(4) symmetric calix[4]resorcinarene, 2-nitroso-5-methoxyphenol, 6-methoxy-2(3H)-benzoxazoloneQuality Control of m-Methoxyphenol

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Ether – Wikipedia,
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The author of 《One step phenol synthesis from benzene catalysed by nickel(II) complexes》 were Muthuramalingam, Sethuraman; Anandababu, Karunanithi; Velusamy, Marappan; Mayilmurugan, Ramasamy. And the article was published in Catalysis Science & Technology in 2019. SDS of cas: 150-19-6 The author mentioned the following in the article:

Nickel(II)complexes of N4-ligands have been synthesized and characterized as efficient catalysts for the hydroxylation of benzene using H2O2. All the complexes exhibited Ni2+ → Ni3+ oxidation potentials of around 0.966-1.051 V vs. Ag/Ag+ in acetonitrile. One of the complexes has been structurally characterized and adopted an octahedral coordination geometry around the nickel(II) center. The complexes catalyzed direct benzene hydroxylation using H2O2 as an oxygen source and afforded phenol up to 41% with a turnover number (TON) of 820. This is unprecedentedly the highest catalytic efficiency achieved to date for benzene hydroxylation using 0.05 mol% catalyst loading and five equivalent of H2O2. The benzene hydroxylation reaction possibly proceeds via the key intermediate bis(μ-oxo)dinickel(III) species, which was characterized by HR-MS, vibrational and electronic spectral methods, for almost all complexes. The formation constant of the key intermediate was calculated to be 5.61-9.41 × 10-2 s-1 by following the appearance of an oxo-to-Ni(III) LMCT band at around 406-413 nm. The intermediates are found to be very short-lived (t1/2, 73-123 s). The geometry of one of the catalytically active intermediates was optimized by DFT and its spectral properties were calculated by TD-DFT calculations, which are comparable to exptl. spectral data. The kinetic isotope effect (KIE) values (0.98-1.05) support the involvement of nickel-bound oxygen species as an intermediate. The isotope-labeling experiments using H218O2 showed 92.46% incorporation of 18O, revealing that H2O2 is the key oxygen supplier to form phenol. The catalytic efficiencies of complexes are strongly influenced by the geometrical configuration of intermediates, and stereoelectronic and steric properties, which are fine-tuned by the ligand architecture. In addition to this study using m-Methoxyphenol, there are many other studies that have used m-Methoxyphenol(cas: 150-19-6SDS of cas: 150-19-6) was used in this study.

m-Methoxyphenol(cas: 150-19-6) may be used as an analytical standard for the determination of the analyte in wine, coffee beans, wood samples, and mainstream smoke by gas chromatography (GC) based techniques.SDS of cas: 150-19-6

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Moraes, Maiara C.; Lenardao, Eder J.; Barcellos, Thiago published their research in ARKIVOC (Gainesville, FL, United States) in 2021. The article was titled 《Synthesis of C4-substituted coumarins via Pechmann condensation catalyzed by sulfamic acid. Insights into the reaction mechanism by HRMS analysis》.SDS of cas: 150-19-6 The article contains the following contents:

A series of functionalized C4-substituted coumarins were synthesized by exploring the reaction of activated and non-activated phenols and β-ketoesters under solvent-free conditions in the presence of sulfamic acid as a Bronsted acid catalyst. Fifteen examples were prepared with moderate to excellent yields (50% to 90%) using 10 mol % of the catalyst. Furthermore, it was possible from the proposed methodol. to scale up the synthesis of coumarins to obtain up to 11 g of product. This work also provides a preliminary insight into the reaction mechanism using high-resolution mass spectrometry anal. The key cinnamic acid derivative intermediate was detected, implying that under the evaluated conditions, the mechanistic pathway starts with an aromatic electrophilic substitution followed by dehydration reaction and intramol. transesterification. In the part of experimental materials, we found many familiar compounds, such as m-Methoxyphenol(cas: 150-19-6SDS of cas: 150-19-6)

m-Methoxyphenol(cas: 150-19-6) may be used in synthesis of:C(4) symmetric calix[4]resorcinarene, 2-nitroso-5-methoxyphenol, 6-methoxy-2(3H)-benzoxazoloneSDS of cas: 150-19-6

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

The author of 《One step phenol synthesis from benzene catalysed by nickel(II) complexes》 were Muthuramalingam, Sethuraman; Anandababu, Karunanithi; Velusamy, Marappan; Mayilmurugan, Ramasamy. And the article was published in Catalysis Science & Technology in 2019. SDS of cas: 150-19-6 The author mentioned the following in the article:

Nickel(II)complexes of N4-ligands have been synthesized and characterized as efficient catalysts for the hydroxylation of benzene using H2O2. All the complexes exhibited Ni2+ → Ni3+ oxidation potentials of around 0.966-1.051 V vs. Ag/Ag+ in acetonitrile. One of the complexes has been structurally characterized and adopted an octahedral coordination geometry around the nickel(II) center. The complexes catalyzed direct benzene hydroxylation using H2O2 as an oxygen source and afforded phenol up to 41% with a turnover number (TON) of 820. This is unprecedentedly the highest catalytic efficiency achieved to date for benzene hydroxylation using 0.05 mol% catalyst loading and five equivalent of H2O2. The benzene hydroxylation reaction possibly proceeds via the key intermediate bis(μ-oxo)dinickel(III) species, which was characterized by HR-MS, vibrational and electronic spectral methods, for almost all complexes. The formation constant of the key intermediate was calculated to be 5.61-9.41 × 10-2 s-1 by following the appearance of an oxo-to-Ni(III) LMCT band at around 406-413 nm. The intermediates are found to be very short-lived (t1/2, 73-123 s). The geometry of one of the catalytically active intermediates was optimized by DFT and its spectral properties were calculated by TD-DFT calculations, which are comparable to exptl. spectral data. The kinetic isotope effect (KIE) values (0.98-1.05) support the involvement of nickel-bound oxygen species as an intermediate. The isotope-labeling experiments using H218O2 showed 92.46% incorporation of 18O, revealing that H2O2 is the key oxygen supplier to form phenol. The catalytic efficiencies of complexes are strongly influenced by the geometrical configuration of intermediates, and stereoelectronic and steric properties, which are fine-tuned by the ligand architecture. In addition to this study using m-Methoxyphenol, there are many other studies that have used m-Methoxyphenol(cas: 150-19-6SDS of cas: 150-19-6) was used in this study.

m-Methoxyphenol(cas: 150-19-6) may be used as an analytical standard for the determination of the analyte in wine, coffee beans, wood samples, and mainstream smoke by gas chromatography (GC) based techniques.SDS of cas: 150-19-6

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem