Category: 150-19-6

《A total synthesis of (+)-brazilin》 was published in Tetrahedron Letters in 2020. These research results belong to Huang, Shuangping; Ou, Wentao; Li, Wang; Xiao, Hesheng; Pang, Yiying; Zhou, Yi; Wang, Xiaoji; Yang, Xihua; Wang, Liping. Safety of m-Methoxyphenol The article mentions the following:

Described herein is a concise total synthesis of (+)-brazilin (I) from readily available 4-bromo-1,2-dimethoxybenzene. In this synthetic route, a Sharpless asym. dihydroxylation was employed to introduce the chiral hydroxyl group, and trifluoroacetic acid (TFA) catalyzed one-pot intramol. tandem Prins/Friedel-Crafts reaction was also involved as the key transformation in the construction of the hybrid chromane and indane framework. The experimental process involved the reaction of m-Methoxyphenol(cas: 150-19-6Safety of m-Methoxyphenol)

m-Methoxyphenol(cas: 150-19-6) may be used in synthesis of:C(4) symmetric calix[4]resorcinarene, 2-nitroso-5-methoxyphenol, 6-methoxy-2(3H)-benzoxazoloneSafety of m-Methoxyphenol

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Ether – Wikipedia,
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Song, Ran; Lian, Zhendong; Feng, Wei; Guan, Tianyi; Si, Wen; Yang, Daoshan; Lv, Jian published an article in 2022. The article was titled 《Palladium-catalyzed decarboxylative O-allylation of phenols with γ-methylidene-δ-valerolactones》, and you may find the article in Organic Chemistry Frontiers.Safety of m-Methoxyphenol The information in the text is summarized as follows:

A novel palladium-catalyzed decarboxylative O-allylation of phenols ArOH (Ar = C6H5, 4-FC6H4, 2-naphthyl, etc.) and 1-OH-2-(CH(OH)R1)C6H3R (R = 5-F, 3-Cl, 3-Me, etc.; R1 = C6H5, 4-FC6H4, 2-naphthyl, etc.) was developed, in which γ-methylidene-δ-valerolactones I (R2 = Me, Ph, 2-thienyl, etc.; R3 = Me, Et) (GMDV) were found to be an efficient and selective allylation reagent, affording the target allyl Ph ethers ArOCH2C(=CH2)CH2CH(R2)C(O)2R3 and II (R4 = 4-F, 5-Cl, 5-Me, etc.) in up to 92% yields under mild conditions. After reading the article, we found that the author used m-Methoxyphenol(cas: 150-19-6Safety of m-Methoxyphenol)

m-Methoxyphenol(cas: 150-19-6) may be used in synthesis of:C(4) symmetric calix[4]resorcinarene, 2-nitroso-5-methoxyphenol, 6-methoxy-2(3H)-benzoxazoloneSafety of m-Methoxyphenol

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2022,Gu, Jia; Xiao, Pan-Lei; Wang, Jie; Zhong, Liang; Nie, Xu-Liang; Peng, Da-Yong published an article in Journal of Molecular Structure. The title of the article was 《Synthesis, crystal structure, spectroscopic characterization and anti-fungal activity of Ethyl 2-Oxo-2H-chromene-3-carboxylate Derivatives》.Quality Control of m-Methoxyphenol The author mentioned the following in the article:

A series of Et 2-oxo-2H-chromene-3-carboxylate derivatives I [R1 = H, CH3, Br, etc.; R2 = H, OCH3] was synthesized by the ester cyclization of di-Et malonate and salicylaldehydes which was obtained from corresponding phenols. The single crystal of compounds I [R1 = OCF3, OCH3; R2 = H] were obtained and characterized by X-ray. Compound I [R1 = OCF3; R2 = H] crystallized in the triclinic system with space group P-1 and compound I [R1 = OCH3; R2 = H] crystallized in the monoclinic system with space group P21/c. The potential anti-fungal activities of the synthesized compounds was studied against five kinds of common fungi at concentrations of 200 ppm and 500 ppm and results showed that the target compounds exhibited certain anti-fungal activity against tested strains. The inhibition rate of compound I [R1 = CH3; R2 = H] was the highest against Fusarium oxysporum, up to 60.29% at 500 ppm. Compound I [R1 = CH3; R2 = H] was promising to become the lead compound of pesticide in the future. In the experiment, the researchers used m-Methoxyphenol(cas: 150-19-6Quality Control of m-Methoxyphenol)

m-Methoxyphenol(cas: 150-19-6) may be used in synthesis of:C(4) symmetric calix[4]resorcinarene, 2-nitroso-5-methoxyphenol, 6-methoxy-2(3H)-benzoxazoloneQuality Control of m-Methoxyphenol

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Ether – Wikipedia,
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Application In Synthesis of m-MethoxyphenolIn 2019 ,《Development of an efficient phenolic sensor based on facile Ag2O/Sb2O3 nanoparticles for environmental safety》 was published in Nanoscale Advances. The article was written by Rahman, Mohammed M.; Alam, M. M.; Asiri, Abdullah M.. The article contains the following contents:

The facile hydrothermal method was used to prepare low-dimensional doped Ag2O/Sb2O3 nanoparticles (NPs) at low temperature in alk. medium. The calcined NPs were characterized in detail by FTIR, UV/vis, FESEM, XPS, EDS, and XRD. A thin layer of Ag2O/Sb2O3 NPs was deposited onto a glassy carbon electrode (GCE) using Nafion (5% Nafion suspension in ethanol) conducting binder, which formed the working electrode of the selective 3-methoxyphenol electrochem. sensor probe. The proposed chem. sensor exhibits high sensitivity, long-term stability, and enhanced electrochem. responses towards 3-methoxyphenol. Response to 3-methoxyphenol is linear over the concentration range (LDR) of 0.09 nM to 0.09 mM. The anal. parameters of the sensor such as sensitivity, stability, response time, linearity, LDR, robustness, selectivity etc. were evaluated by an electrochem. approach. The sensor probe fabricated with Ag2O/Sb2O3 NPs seems to be a promising candidate for effective and reliable electrochem. detection of hazardous and carcinogenic chems. in the environment and health care fields in large scales. In addition to this study using m-Methoxyphenol, there are many other studies that have used m-Methoxyphenol(cas: 150-19-6Application In Synthesis of m-Methoxyphenol) was used in this study.

m-Methoxyphenol(cas: 150-19-6) may be used as an analytical standard for the determination of the analyte in wine, coffee beans, wood samples, and mainstream smoke by gas chromatography (GC) based techniques.Application In Synthesis of m-Methoxyphenol

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Ether – Wikipedia,
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In 2019,Organic Chemistry Frontiers included an article by Song, Zehua; Wang, Guotong; Li, Wei; Li, Shengkun. Recommanded Product: m-Methoxyphenol. The article was titled 《Innate pharmacophore assisted selective C-H functionalization to therapeutically important nicotinamides》. The information in the text is summarized as follows:

The application of the pre-validated pharmacophore 2-(2-oxazolinyl)anilines (R)/(S)-I (R = H, Me, Et, benzyl) as an innate directing group in the C-H etherification and amination of nicotinamides II for the efficient synthesis of drug- and agrochem.-like mols. was determined An operationally simple, and regioselective C-H functionalization of nicotinamides (R)/(S)-II was first accomplished using a complicated variation of copper salts. All the specific procedures used were easy to utilize, without external oxidants or ligands. The feasibility is highlighted using an alternative synthesis of diflufenican with a rapid synthesis of niacin related pharmaceuticals or analogs III (R1 = H, 3-CH3OC6H4O, 2-methoxy-4-(prop-2-en-1-yl)phenyl, 4-methylpiperidin-1-yl, etc.; R2 = H, 2-methoxy-4-(prop-2-en-1-yl)phenyl, 3-methylpiperidin-1-yl, etc.). In the experiment, the researchers used many compounds, for example, m-Methoxyphenol(cas: 150-19-6Recommanded Product: m-Methoxyphenol)

m-Methoxyphenol(cas: 150-19-6) may be used in synthesis of:C(4) symmetric calix[4]resorcinarene, 2-nitroso-5-methoxyphenol, 6-methoxy-2(3H)-benzoxazoloneRecommanded Product: m-Methoxyphenol

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Ether – Wikipedia,
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The author of 《Jet-cooled rovibrational spectroscopy of methoxyphenols using two complementary FTIR and QCL based spectrometers》 were Asselin, P.; Bruckhuisen, J.; Roucou, A.; Goubet, M.; Martin-Drumel, M.-A.; Jabri, A.; Belkhodja, Y.; Soulard, P.; Georges, R.; Cuisset, A.. And the article was published in Journal of Chemical Physics in 2019. Safety of m-Methoxyphenol The author mentioned the following in the article:

Methoxyphenols (MPs) are a significant component of biomass burning emissions which mainly exists in our atm. in the gas phase where they contribute to the formation of secondary organic aerosols (SOAs). Rovibrational spectroscopy is a promising tool to monitor atm. MPs and infer their role in SOA formation. In this study, we bring a new perspective on the rovibrational anal. of MP isomers by taking advantage of two complementary devices combining jet-cooled environments and absorption spectroscopy: the Jet-AILES and the SPIRALES setups. Based on Q-branch frequency positions measured in the Jet-AILES Fourier-transform IR (FTIR) spectra and guided by quantum chem. calculations, we propose an extended vibrational and conformational anal. of the different MP isomers in their fingerprint region. Some modes such as far-IR out-of-plane -OH bending or mid-IR in-plane -CH bending allow us to assign individually all the stable conformers. Finally, using the SPIRALES setup with three different external cavity quantum cascade laser sources centered on the 930-990 cm-1 and the 1580-1690 cm-1 ranges, it was possible to proceed to the rovibrational anal. of the ν18 ring in-plane bending mode of the MP meta isomer providing a set of reliable excited state parameters, which confirms the correct assignment of two conformers. Interestingly, the observation of broad Q-branches without visible P- and R-branches in the region of the C-C ring stretching bands was interpreted as being probably due to a vibrational perturbation. These results highlight the complementarity of broadband FTIR and narrowband laser spectroscopic techniques to reveal the vibrational conformational signatures of atm. compounds over a large IR spectral range. (c) 2019 American Institute of Physics. The experimental process involved the reaction of m-Methoxyphenol(cas: 150-19-6Safety of m-Methoxyphenol)

m-Methoxyphenol(cas: 150-19-6) may be used in synthesis of:C(4) symmetric calix[4]resorcinarene, 2-nitroso-5-methoxyphenol, 6-methoxy-2(3H)-benzoxazoloneSafety of m-Methoxyphenol

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

The author of 《Kinetic and Theoretical Study of the Atmospheric Aqueous-Phase Reactions of OH Radicals with Methoxyphenolic Compounds》 were He, Lin; Schaefer, Thomas; Otto, Tobias; Kroflic, Ana; Herrmann, Hartmut. And the article was published in Journal of Physical Chemistry A in 2019. Name: m-Methoxyphenol The author mentioned the following in the article:

Methoxyphenols, which are emitted through biomass burning, are an important species in atm. chem. In the present study, temperature-dependent aqueous-phase OH radical reactions of six methoxyphenols and two related phenols have been investigated through laser flash photolysis and the d. functional theory. The rate constants obtained were in a range of (1.1-1.9) × 1010 L mol-1 s-1 with k(3-MC) > k(Cre) ≈ k(Syr) ≈ k(MEP) > k(Res) > k(3-MP) > k(2-EP) ≈ k(2-MP). We derived the parameters of these reactions from the obtained T-dependent rate constants and found a mean Arrhenius activation energy of 16.9 kJ mol-1. The diffusion rate constants were calculated for each case and compared to the measured ones. Generally, the rate constants are found to be close to fully diffusion-controlled (kdiff = (1.4-1.5) × 1010 L mol-1 s-1 for all reactions). A structure-function relationship was established through the measurement result, which could be used for predicting unknown rate constants of other phenolic compounds All of these findings are expected to enhance the predictive capabilities of models, such as the chem. aqueous-phase radical mechanism. In the part of experimental materials, we found many familiar compounds, such as m-Methoxyphenol(cas: 150-19-6Name: m-Methoxyphenol)

m-Methoxyphenol(cas: 150-19-6) may be used in synthesis of:C(4) symmetric calix[4]resorcinarene, 2-nitroso-5-methoxyphenol, 6-methoxy-2(3H)-benzoxazoloneName: m-Methoxyphenol

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2022,Chaves-Carballo, Katherine; Lamoureux, Guy V.; Perez, Alice L.; Bella Cruz, Alexandre; Cechinel Filho, Valdir published an article in RSC Advances. The title of the article was 《Novel one-pot synthesis of a library of 2-aryloxy-1,4-naphthoquinone derivatives. Determination of antifungal and antibacterial activity》.Name: m-Methoxyphenol The author mentioned the following in the article:

The development of new antibiotics and inexpensive antifungals is an important field of research. Based on the privileged pharmacophore of lawsone, a series of phenolic ether derivatives of 1,4-naphthoquinone I (R = H, CH3, OCH3, etc.; R1 = H, NO2, Cl, etc.; R2 = H, OCH3, Br, etc.; R3 = H, Cl, CH3, etc.; R4 = H, Br, Cl, etc.) were synthesized easily in one step in reasonable yields. All the new compounds were characterized and tested as potential antifungal and antibacterial agents. Compound I (R1, R2, R4 = H; R3 = Cl; R = 2,4-Cl2C6H3O) has significant antibacterial action (as good as or better than the controls) against E. coli and S. aureus. Against C. albicans, compounds I (R1, R2, R3, R4 = H; R = Br), (R1, R2, R3, R4 = H; R = Cl), (R, R2, R3, R4 = H; R1 = Cl), (R, R2, R3, R4 = H; R1 = CH3) were the best candidates as antifungals. Using a qual. structure-activity anal., a correlation between molar mass and antimicrobial activity was identified, regardless of the substituent group on the phenolic moiety, except for I (R1, R2, R4 = H; R3 = Cl; R = 2,4-Cl2C6H3O) and (R1, R3, R4 = H; R, R2 = Cl) where electronic effects seem more important. An in silico evaluation of the absorption, distribution, metabolism and excretion (ADME) for I (R, R2, R3, R4 = H; R1 = NO2), (R1, R2, R3, R4 = H; R = NO2), (R1, R2, R4 = H; R3 = Cl; R = 2,4-Cl2C6H3O) and (R1, R3, R4 = H; R, R2 = Cl) was made, indicating that the classic Lipinski’s rule of five applies in all cases. In the experiment, the researchers used m-Methoxyphenol(cas: 150-19-6Name: m-Methoxyphenol)

m-Methoxyphenol(cas: 150-19-6) may be used in synthesis of:C(4) symmetric calix[4]resorcinarene, 2-nitroso-5-methoxyphenol, 6-methoxy-2(3H)-benzoxazoloneName: m-Methoxyphenol

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

The author of 《Iodine(III)-Catalyzed Electrophilic Nitration of Phenols via Non-Bronsted Acidic NO2+ Generation》 were Juarez-Ornelas, Kevin A.; Jimenez-Halla, J. Oscar C.; Kato, Terumasa; Solorio-Alvarado, Cesar R.; Maruoka, Keiji. And the article was published in Organic Letters in 2019. Related Products of 150-19-6 The author mentioned the following in the article:

The first catalytic procedure for the electrophilic nitration of phenols was developed using iodosylbenzene as an organocatalyst based on iodine(III) and aluminum nitrate as a nitro group source. This atom-economic protocol occurs under mild, non-Bronsted acidic and open-flask reaction conditions with a broad functional-group tolerance including several heterocycles. D. functional theory (DFT) calculations at the (SMD:MeCN)Mo8-HX/(LANLo8+f,6-311+G*) level indicated that the reaction proceeds through a cationic pathway that efficiently generates the NO2+ ion, which is the nitrating species under neutral conditions. After reading the article, we found that the author used m-Methoxyphenol(cas: 150-19-6Related Products of 150-19-6)

m-Methoxyphenol(cas: 150-19-6) may be used as an analytical standard for the determination of the analyte in wine, coffee beans, wood samples, and mainstream smoke by gas chromatography (GC) based techniques.Related Products of 150-19-6

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《Coordination Polymers as a Functional Material for the Selective Molecular Recognition of Nitroaromatics and ipso-Hydroxylation of Arylboronic Acids》 was written by Rani, Pooja; Husain, Ahmad; Bhasin, K. K.; Kumar, Girijesh. Safety of m-MethoxyphenolThis research focused onzinc cadmium pyridinylnaphthalenecarboxamide polymer preparation hydroxylation catalyst; fluorescent sensor zinc cadmium pyridinylnaphthalenecarboxamide polymer; crystal structure zinc cadmium pyridinylnaphthalenecarboxamide polymer; Coordination polymer; Fluorescence; Nitroaromatics; Quenching Efficiency; Sensing; ipso-Hydroxylation. The article conveys some information:

We report the synthesis and structural characterization of two coordination polymers (CPs), namely; [{Zn(L)(DMF)4} · 2BF4]α (1) and [{Cd(L)2(Cl)2} · 2H2O]α (2) (where L=N2,N6-di(pyridin-4-yl)naphthalene-2,6-dicarboxamide). Crystal packing of 1 reveals the existence of channels running along the b- and c-axis filled by the ligated DMF and lattice anions, resp. Whereas, crystal packing of 2 reveals that the metallacycles of each 1D chain are intercalating into the groove of adjacent metallacycles resulting in the stacking of 1D loop-chains to form a sheet-like architecture. In addition, both 1 and 2 were exploited as multifunctional materials for the detection of nitroarom. compounds (NACs) as well as a catalyst in the ipso-hydroxylation of aryl/heteroarylboronic acids. Remarkably, 1 and 2 showed high fluorescence stability in an aqueous medium and displayed a maximum 88% and 97% quenching efficiency for 4-NPH, resp. among all the investigated NACs. The mechanistic investigation of NACs recognition suggested that the fluorescence quenching occurred via electron as well as energy transfer process. Furthermore, the ipso-hydroxylation of aryl/heteroarylboronic acids in presence of 1 and 2 gave up to 99% desired product yield within 15 min in our established protocol. In both cases, 1 and 2 are recyclable upto five cycles without any significant loss in their efficiency.m-Methoxyphenol(cas: 150-19-6Safety of m-Methoxyphenol) was used in this study.

m-Methoxyphenol(cas: 150-19-6) may be used as an analytical standard for the determination of the analyte in wine, coffee beans, wood samples, and mainstream smoke by gas chromatography (GC) based techniques.Safety of m-Methoxyphenol

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem