Category: 14807-75-1

Ratajczak, H. M. published the artcilePolarographic studies on aqueous formamidine disulfide solutions. I, Category: ethers-buliding-blocks, the publication is Electrochimica Acta (1975), 20(6-7), 427-9, database is CAplus.

The polarog. reduction of [H2NC(:NH)S]2 (I) in aqueous solution, prepared by oxidation of CS(NH2)2 with H2O2 and by in situ polarog. oxidation of CS(NH2)2 with Ce(IV), was dependent on the acidity of the solution and 3 reduction waves were observed The wave at lowest limiting current was assigned to reduction of the protonated formamidine disulfide [(NH2)2CS]22+ and the second wave to the reduction of a less protonated form. The wave at highest limiting current was due to the reduction of a polysulfide compound formed by reaction of S, from the minor decomposition of I, with I.

Electrochimica Acta published new progress about 14807-75-1. 14807-75-1 belongs to ethers-buliding-blocks, auxiliary class Salt,Thiourea,Amine,Aliphatic hydrocarbon chain, name is Formamidine disulfide dihydrochloride, and the molecular formula is C2H8Cl2N4S2, Category: ethers-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Madhiri, Nicholas published the artcileOxyhalogen-sulfur chemistry: kinetics and mechanism of oxidation of formamidine disulfide by acidic bromate, Safety of Formamidine disulfide dihydrochloride, the publication is Physical Chemistry Chemical Physics (2003), 5(19), 4149-4156, database is CAplus.

The kinetics and mechanism of the oxidation of formamidine disulfide, FDS, a dimer and major metabolite of thiourea, by bromate were studied in acidic media. In excess bromate conditions the reaction displays an induction period before formation of Br. The stoichiometry of the reaction is: 7BrO₃^– + 3[H₂N(HN:)CS-]₂ + 9H₂O → 6NH₂CONH₂ + 6SO₄^2- + 7Br^– + 12H⁺ (A). In excess oxidant conditions, however, the bromide formed in reaction A reacts with bromate to give Br and a final stoichiometry of: 14BrO₃^– + 5[H₂N(HN:)CS-]₂ + 8H₂O → 10NH₂CONH₂ + 10SO₄^2- + 7Br₂ + 6H⁺ (B). The direct reaction of Br and FDS was also studied and its stoichiometry is: 7Br₂ + [H₂N(HN:)CS-]₂ + 10H₂O → 2NH₂CONH₂ + 2SO₄^2- + 14Br^– + 18H⁺ (C). The overall rate of reaction A, as measured by the rate of consumption of FDS, is second order in acid concentrations, indicating the dominance of oxyhalogen kinetics which control the formation of the reactive species HBrO₂ and HOBr. The reaction proceeds through an initial cleavage of the S-S bond to give the unstable sulfenic acids which are then rapidly oxidized through the sulfinic and sulfonic acids to give sulfate. The formation of Br coincides with formation of sulfate because the cleavage of the C-S bond to give sulfate occurs at the sulfonic acid stage only. The mechanism derived is the same as that derived for the bromate-thiourea reaction, suggesting that FDS is an intermediate in the oxidation of thiourea to its oxo-acids as well as to sulfate.

Physical Chemistry Chemical Physics published new progress about 14807-75-1. 14807-75-1 belongs to ethers-buliding-blocks, auxiliary class Salt,Thiourea,Amine,Aliphatic hydrocarbon chain, name is Formamidine disulfide dihydrochloride, and the molecular formula is C2H8Cl2N4S2, Safety of Formamidine disulfide dihydrochloride.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Joshua, C. P. published the artcileOxidation of mixtures of s-diarylthiocarbamides and thiocarbamide. Formation of 3-amino-4-aryl-5-arylimino-1,2,4Δ2-thiadiazolines, Computed Properties of 14807-75-1, the publication is Indian Journal of Chemistry (1973), 11(12), 1272-5, database is CAplus.

Oxidation of an acid alc. solution of a binary mixture of s-diphenyl-, s-di-o-tolyl- or s-di-p-tolylthiocarbamide and thiocarbamide yields the related 3-amino-4-aryl-5-(arylimino)-1,2,4-Δ2-thiadiazoline (I). A mechanism of formation is described.

Indian Journal of Chemistry published new progress about 14807-75-1. 14807-75-1 belongs to ethers-buliding-blocks, auxiliary class Salt,Thiourea,Amine,Aliphatic hydrocarbon chain, name is Formamidine disulfide dihydrochloride, and the molecular formula is C2H8Cl2N4S2, Computed Properties of 14807-75-1.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Joshua, C. P. published the artcileOxidation of mixtures of thiocarbamides. II. Oxidation of mixtures of 1-alkyl-3-arylthiocarbamides and thiocarbamide. Formation of 3-amino-5-alkylimino-4-aryl-1,2,4-Δ2-thiadiazolines, Formula: C2H8Cl2N4S2, the publication is Indian Journal of Chemistry (1974), 12(9), 962-5, database is CAplus.

Oxidation of mixtures of 1-alkyl-3-arylthiocarbamides and thiocarbamide yielded 3-amino-5-alkylimino-4-aryl-1,2,4-Δ2-thiadiazolines. The role of 1-amidino-3-alkyl-1-arylthiocarbamide-HCl as intermediates in the oxidation was established by their isolation under mild conditions. The 1-amidino-3-alkyl-1-arylthiocarbamide salts and 3-amino-5-alkylimino-4-aryl-1-2,4-Δ2-thiadiazolines are interconvertible by oxidation-reduction Interactions between bis(N-alkyl-N’-aryl)dithioformamidine dihydrochlorides and dithioformamidine dihydrochloride also lead to 1-amidino-3-alkyl-1-arylthiocarbamide salts.

Indian Journal of Chemistry published new progress about 14807-75-1. 14807-75-1 belongs to ethers-buliding-blocks, auxiliary class Salt,Thiourea,Amine,Aliphatic hydrocarbon chain, name is Formamidine disulfide dihydrochloride, and the molecular formula is C2H8Cl2N4S2, Formula: C2H8Cl2N4S2.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Rio, L. Garcia published the artcileKinetic study of the stability of (NH₂)₂CSSC(NH₂)₂²⁺, Safety of Formamidine disulfide dihydrochloride, the publication is Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1996), 159-62, database is CAplus.

The kinetics of the decomposition of formamidine disulfide dihydrochloride, (NH₂)₂CSSC(NH₂)₂²⁺ 2Cl^–, in aqueous solution at 25° are general base catalyzed, and rate constants were measured over the pH range 1.91-9.03. Anal. of the data yields ionization constants pK₁ = 5.49, pK₂ = 7.66 and rate constants for deprotonation of the substrate by OH^– and H₂O. For the doubly charged cation, reaction occurs through a small concentration of a reactive tautomer, (HN=)(NH₃⁺)CSSC⁺(NH₂)₂, which is attacked by H₂O. The singly charged cation reacts by parallel pathways involving OH^– and H₂O as attacking bases.

Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry published new progress about 14807-75-1. 14807-75-1 belongs to ethers-buliding-blocks, auxiliary class Salt,Thiourea,Amine,Aliphatic hydrocarbon chain, name is Formamidine disulfide dihydrochloride, and the molecular formula is C2H8Cl2N4S2, Safety of Formamidine disulfide dihydrochloride.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Bombicz, Petra published the artcileSynthesis, vibrational spectra and X-ray structures of copper(I) thiourea complexes, Safety of Formamidine disulfide dihydrochloride, the publication is Inorganica Chimica Acta (2004), 357(2), 513-525, database is CAplus.

Complex formation of thiourea with Cu takes place as an intermediate step in the preparation of Cu sulfide thin films by spray pyrolysis starting from aqueous solutions of Cu(II) chloride and thiourea. The stoichiometry of the complex and that of the resulting thin film primarily depends on the mol. ratio of the starting materials. For comparison, the structures of all Cu(I) thiourea complexes found in the Cambridge Structural Database are classified. Syntheses, structural (single crystal XRD also at low temperature 193 K) and spectroscopic studies (FTIR and Raman) of six Cu-thiourea complexes are now reported. The Cu to thiourea stoichiometric ratio is 1:3 in four of these complexes, but their structures are basically different as dimerization or polymer formation takes place depending on whether the H₂O of crystallization is present or absent. The structure of bis(μ-thiourea)tetrakis(thiourea)dicopper(I) dichloride dihydrate, [Cu₂(tu)₆]Cl₂·2H₂O (1) was determined at room and also at low temperature Bis(μ-thiourea)tetrakis(thiourea)dicopper(I) dibromide dihydrate, [Cu₂(tu)₆]Br₂·2H₂O (2) is isomorphous with 1, and the anhydrous compounds chlorotris(thiourea)copper(I), [Cu(tu)₃]Cl (3) and bromotris(thiourea)copper(I), [Cu(tu)₃]Br (4) are isomorphous. In the 3rd isomorphous pair of complexes the Cu to thiourea stoichiometric ratio is 1:1, viz. chloro(thiourea)copper(I) hemihydrate, [Cu(tu)]Cl·0.5H₂O (5) and bromo(thiourea)copper(I) hemihydrate, [Cu(tu)]Br·0.5H₂O (6). During the preparation of chloro(thiourea)copper(I) hemihydrate (5) a reaction byproduct α,α^‘-dithiobisformamidinium dichloride, [SC(NH₂)₂]₂Cl₂ (7) was identified and structurally characterized which made it possible to suggest a reaction path leading to complex formation.

Inorganica Chimica Acta published new progress about 14807-75-1. 14807-75-1 belongs to ethers-buliding-blocks, auxiliary class Salt,Thiourea,Amine,Aliphatic hydrocarbon chain, name is Formamidine disulfide dihydrochloride, and the molecular formula is C2H8Cl2N4S2, Safety of Formamidine disulfide dihydrochloride.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Ledovskikh, V. M. published the artcilePolarographic study of the reaction of thiourea with copper(II) sulfate, COA of Formula: C2H8Cl2N4S2, the publication is Zhurnal Obshchei Khimii (1976), 46(1), 11-15, database is CAplus.

Results are given on the reaction of thiourea [62-56-6] and some of its derivatives with CuSO4 [7758-98-7] in H2SO4 solutions by using the polarog. method. The anomalous behavior can be explained by the presence of highly surface-active complexes of Cu(I) with thiourea. The thiourea and its derivatives is oxidized by the Cu(II) ion to form the appropriate formamidine disulfide, together with complexes of the original substance with Cu(I). Quant. determination of the products of the reaction are possible by polarog. The presence in the H2SO4 electrolyte of Cu compounds of the disulfide class is a necessary condition for the brightening action of dimethylolthiourea [3084-25-1] and its dialkyl esters.

Zhurnal Obshchei Khimii published new progress about 14807-75-1. 14807-75-1 belongs to ethers-buliding-blocks, auxiliary class Salt,Thiourea,Amine,Aliphatic hydrocarbon chain, name is Formamidine disulfide dihydrochloride, and the molecular formula is C2H8Cl2N4S2, COA of Formula: C2H8Cl2N4S2.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Karelin, A. A. published the artcileInhibition of serum transamidinase by formamidine disulfide. Identification of the SH-group at the active site of the enzyme, Formula: C2H8Cl2N4S2, the publication is Biokhimiya (Moscow) (1972), 37(3), 652-5, database is CAplus and MEDLINE.

Formamidine disulfide (I) [14807-75-1] inhibited the activity of serum transamidinase (EC 2.1.4.1) [9027-35-4] from patients with pancreonecrosis by 50% at 10-6M and by 90% at 2.2 .tim. 10-6M. Preincubation of serum transamidinase with 1 μg trypsin [9002-07-7] increased the inhibitory effect of I. L-canavanine [543-38-4], an amidine donor which is the substrate of the reaction, efficiently protected the activity of the enzyme. Apparently, intactness of the substrate amidine binding region of the enzyme containing the essential sulfhydryl group is the main condition of the preservation of enzymic activity in the blood.

Biokhimiya (Moscow) published new progress about 14807-75-1. 14807-75-1 belongs to ethers-buliding-blocks, auxiliary class Salt,Thiourea,Amine,Aliphatic hydrocarbon chain, name is Formamidine disulfide dihydrochloride, and the molecular formula is C2H8Cl2N4S2, Formula: C2H8Cl2N4S2.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Gattow, G. published the artcileOxidation products of thiourea, Recommanded Product: Formamidine disulfide dihydrochloride, the publication is Zeitschrift fuer Anorganische und Allgemeine Chemie (1988), 66-72, database is CAplus.

(H₂N)₂CSSC(NH₂)₂Cl₂ (I) was obtained by H₂O₂ oxidation of thiourea in presence of HCl. Treatment of I with NaH gave H₂N(HN:)CSSC(:NH)NH₂ (II). Neither I nor II, nor (H₂N)₂CSO₂ reacted with CS₂ or chlorodithioformates.

Zeitschrift fuer Anorganische und Allgemeine Chemie published new progress about 14807-75-1. 14807-75-1 belongs to ethers-buliding-blocks, auxiliary class Salt,Thiourea,Amine,Aliphatic hydrocarbon chain, name is Formamidine disulfide dihydrochloride, and the molecular formula is C2H8Cl2N4S2, Recommanded Product: Formamidine disulfide dihydrochloride.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Peyronel, Giorgio published the artcileInfrared investigations on the dithioformamidinium dihalides, Name: Formamidine disulfide dihydrochloride, the publication is Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy (1983), 39A(7), 617-20, database is CAplus.

[((H₂N)₂CS)₂]X₂.H₂O (X = Cl, Br, I) and the anhydrous dibromide were investigated by IR spectroscopy. The νNH and δNH₂ bands were identified from the deuterated dithioformamidinium diiodide. With respect to thiourea the νNH and δNH₂ frequencies decreased and increased resp., as in other S-bonded derivatives of thiourea, and the ν_asCN₂ and νCS frequencies increased and decreased resp., in agreement with the increased CN double bond character and the formation of a C-S single bond.

Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy published new progress about 14807-75-1. 14807-75-1 belongs to ethers-buliding-blocks, auxiliary class Salt,Thiourea,Amine,Aliphatic hydrocarbon chain, name is Formamidine disulfide dihydrochloride, and the molecular formula is C2H8Cl2N4S2, Name: Formamidine disulfide dihydrochloride.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem