Category: 135-02-4

Related Products of 135-02-4In 2019 ,《Novel Fe3O4/SiO2/PPA Magnetic Nanoparticles: Preparation, Characterization, and First Catalytic Application to the Solvent- Free Synthesis of Tetrahydrobenzo[a]xanthene-11-ones》 was published in Russian Journal of Organic Chemistry. The article was written by Amarloo, F.; Zhiani, R.; Mehrzad, J.. The article contains the following contents:

Novel Fe3O4/SiO2/PPA nanoparticles were used as solid acid support in the solvent-free synthesis of 12-aryl-9,9-dimethyl-8,9,10,12-tetrahydro-11H-benzo[a]xanthen-11-ones I (R = H, 4-Me, 2-MeO, 4-MeO, 2-Cl, 4-Cl) via multicomponent condensation of aromatic aldehydes with naphthalen-2-ol and 5,5-dimethylcyclohexane-1,3-dione. The target products were obtained in good to high yields. The Fe3O4/SiO2/PPA nanoparticles were thoroughly characterized by SEM, transmission electron microscopy, Fourier-transform IR spectroscopy, and energy-dispersive C-ray spectroscopy. The new catalyst has a high activity and is environmentally friendly, heterogeneous, easily recoverable, and recyclable without loss of catalytic activity. In the experimental materials used by the author, we found 2-Methoxybenzaldehyde(cas: 135-02-4Related Products of 135-02-4)

2-Methoxybenzaldehyde(cas: 135-02-4) is found in cassia oil, cinnamon bark, and cinnamon bark oil. It is a clear colorless liquid with a strong aroma. It has been used to examine the acaricidal activity of Periploca sepium oil and its active component against Tyrophagus putrescentiae.Related Products of 135-02-4

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Recommanded Product: 135-02-4In 2019 ,《Introduction of piperazine-1,4-diium dihydrogen phosphate as a new and highly efficient dicationic Bronsted acidic ionic salt for the synthesis of (thio)barbituric acid derivatives in water》 appeared in Journal of Molecular Structure. The author of the article were Darvishzad, Shila; Daneshvar, Nader; Shirini, Farhad; Tajik, Hassan. The article conveys some information:

A new piperazine-based dicationic Bronsted acidic ionic salt named as piperazine-1,4-diium dihydrogen phosphate was prepared After characterization by FT-IR, Mass and NMR spectroscopy, it was used as an efficient and reusable catalyst for the synthesis of 5-arylidenepyrimidine-2,4,6(1H,3H,5H)-trione and pyrano[2,3-d]pyrimidinone (thione) derivatives Some of the advantages of this method were utilization of low amount of the catalyst, ease of work-up, short reaction times, excellent yields and acceptable reusability of the catalyst. In the experiment, the researchers used many compounds, for example, 2-Methoxybenzaldehyde(cas: 135-02-4Recommanded Product: 135-02-4)

2-Methoxybenzaldehyde(cas: 135-02-4) is found in cassia oil, cinnamon bark, and cinnamon bark oil. It is a clear colorless liquid with a strong aroma. It has been used to examine the acaricidal activity of Periploca sepium oil and its active component against Tyrophagus putrescentiae.Recommanded Product: 135-02-4

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Electric Literature of C8H8O2In 2019 ,《Green one-pot multicomponent synthesis of pyrrolidinones using planetary ball milling process under solvent-free conditions》 appeared in Synthetic Communications. The author of the article were Khaligh, Nader Ghaffari; Mihankhah, Taraneh; Johan, Mohd Rafie. The article conveys some information:

A novel and efficient protocol was presented for the synthesis of pyrrolidinones I [R1 = H, 2-NO2, 4-Cl, etc.; R2 = Et, Me; R3 = H, 4-Me, 4-OMe, 4-NO2] via multicomponent condensation of benzaldehydes, dialkyl butynedioates and anilines using catalytic loading of 1,1′-butylene-bis(3-sulfo-3H-imidazol-1-ium)hydrogen sulfate as recyclable Bronsted acid ionic liquid through ball milling process at room temperature under solvent-free conditions. The developed method provided good to excellent yields of various pyrrolidinones in environmentally friendly conditions. Furthermore, this efficient protocol displayed a combination of the synthetic advantage of one-pot multicomponent reaction with ecol. benefits and convenience of a mechanochem. procedure. The results came from multiple reactions, including the reaction of 2-Methoxybenzaldehyde(cas: 135-02-4Electric Literature of C8H8O2)

2-Methoxybenzaldehyde(cas: 135-02-4) is found in cassia oil, cinnamon bark, and cinnamon bark oil. It is a clear colorless liquid with a strong aroma. It has been used to examine the acaricidal activity of Periploca sepium oil and its active component against Tyrophagus putrescentiae.Electric Literature of C8H8O2

Referemce:
Ether – Wikipedia,
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Salihovic, Mirsada; Pazalja, Mirha; Spirtovic Halilovic, Selma; Veljovic, Elma; Mahmutovic-Dizdarevic, Irma; Roca, Suncica; Novakovic, Irena; Trifunovic, Snezana published their research in Journal of Molecular Structure in 2021. The article was titled 《Synthesis, characterization, antimicrobial activity and DFT study of some novel Schiff bases》.Related Products of 135-02-4 The article contains the following contents:

Two new Schiff bases I (R = Cl, OMe) derived from L-cysteine and substituted benzaldehyde were synthesized. DFT calculations were based on global chem. reactivity indexes calculated using the B3LYP/6-31G*, B3LYP/6-31G**, and B3LYP/6-31+G* theory levels. Exptl. and theor. obtained values for FT-IR and NMR (1H, 13C) of test compounds showed good agreement. The reactivity descriptors of B3LYP (E, EHOMO, ELUMO, dipole moment, Δε, μ, η, ω) were calculated to predict the stability of newly synthesized compounds The microbiol. activity of the compounds was tested on several Gram-pos. bacteria: Staphylococcus aureus, Bacillus subtilis, Clostridium sporogenes, Microccocus luteus and Microccocus flavus. The following Gram-neg. bacteria were used to test the compounds: Escherichia coli, Pseudomonas aeruginosa Proteus hauseri, Klebsiella pneumoniae, Salmonella enterica subsp. enterica serovar Enteritidis. Also, the activity on the following yeasts was examined: Candida albicans, Saccharomyces cerevisiae and fungal strain Aspergillus brasilliensis. The Schiff base with chlorine in the structure has the best antimicrobial action against all tested microorganisms. The selected quantum chem. descriptors calculated for both compounds have a close relationship with the antimicrobial activity. After reading the article, we found that the author used 2-Methoxybenzaldehyde(cas: 135-02-4Related Products of 135-02-4)

2-Methoxybenzaldehyde(cas: 135-02-4) is used as a flavor agent in foods including nonalcoholic/alcoholic beverages, baked goods, chewing gum, confections, frozen dairy, fruit ices, hard/soft candy, instant coffee, tea, Jams, jellies, and milk products. It also has been used to obtain good enantioselectivities using Cu(OAc)(2)-bis(oxazolines) via hydrogen bonding in asymmetric Henry reaction.Related Products of 135-02-4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Electric Literature of C8H8O2In 2020 ,《Introduction of a new catalyst containing an ionic liquid bridge on nanoporous Na+- montmorillonite for the synthesis of hexahydroquinolines and 1,8-dioxo-decahydroacridines via Hantzsch condensation》 was published in Journal of Molecular Structure. The article was written by Mazloumi, Masoumeh; Shirini, Farhad. The article contains the following contents:

A new nanoporous catalyst formulated as Na+-MMT-[bip]-NH+2 HSO-4 was prepared via modification of Na+-MMT with bis-3-(trimethoxysilylpropyl)-amine and then addition of sulfuric acid. In continue the prepared reagent was identified with different methods including Fourier-transform IR spectroscopy (FT-IR), X-ray diffraction (XRD), field emission SEM (FESEM), thermogravimetric anal. (TGA), transmission electron microscopy (TEM), energy dispersive spectrometer (EDS) and CHN elemental anal. After identification the catalytic efficiency of this reagent was tested in the synthesis of hexahydroquinolines and 1,8-dioxo-decahydroacridines via Hantzsch condensations. All reactions were performed under mild conditions in the absence of solvent in high yields in short reaction times. The catalyst was also reusable for several times in both of the studied reactions. After reading the article, we found that the author used 2-Methoxybenzaldehyde(cas: 135-02-4Electric Literature of C8H8O2)

2-Methoxybenzaldehyde(cas: 135-02-4) is found in cassia oil, cinnamon bark, and cinnamon bark oil. It is a clear colorless liquid with a strong aroma. It has been used to examine the acaricidal activity of Periploca sepium oil and its active component against Tyrophagus putrescentiae.Electric Literature of C8H8O2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

HPLC of Formula: 135-02-4In 2019 ,《Aqueous hydrotropic solution: green reaction medium for synthesis of pyridopyrimidine carbonitrile and spiro-oxindole dihydroquinazolinone derivatives》 appeared in Research on Chemical Intermediates. The author of the article were Patil, Audumbar; Mane, Ananda; Kamat, Siddharth; Lohar, Trushant; Salunkhe, Rajashri. The article conveys some information:

An efficient multicomponent domino approach for synthesis of pyridopyrimidine carbonitriles I [R = 2-NO2, 4-Me, 3-Cl, etc.] and spiro-oxindole dihydroquinazolinones II [R1 = 3-NO2, 4-CN, 3-OH, etc.] by one-pot reaction in 50 % aqueous sodium p-toluene sulfonate (NaPTS) solution at ambient reaction condition was reported. The merits of present protocol were short reaction time, excellent product yield with high purity, easy workup procedure and reusability of reaction medium. The results came from multiple reactions, including the reaction of 2-Methoxybenzaldehyde(cas: 135-02-4HPLC of Formula: 135-02-4)

2-Methoxybenzaldehyde(cas: 135-02-4) is found in cassia oil, cinnamon bark, and cinnamon bark oil. It is a clear colorless liquid with a strong aroma. It has been used to examine the acaricidal activity of Periploca sepium oil and its active component against Tyrophagus putrescentiae.HPLC of Formula: 135-02-4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,Research on Chemical Intermediates included an article by Salami, Masoumeh; Ezabadi, Ali. Application In Synthesis of 2-Methoxybenzaldehyde. The article was titled 《A caffeine-based ionic liquid as a novel and eco-friendly catalyst for the synthesis of 1,8-dioxo-octahydroxanthenes under solvent-free conditions》. The information in the text is summarized as follows:

A new Bronsted acidic ionic liquid has been synthesized using caffeine and p-toluenesulfonic acid as precursors. The IL was fully characterized by FT-IR, 1H NMR, 13C NMR, MS, elemental anal., as well as Hammett acidity function. The prepared reagent is efficiently able to catalyze the synthesis of 1,8-dioxo-octahydroxanthenes under solvent-free conditions. Various advantages associated with this method include novelty and easy preparation of catalyst, simple work-up procedure and purification, short reaction times, high product yields, and easy recovery and reusability of the catalyst. After reading the article, we found that the author used 2-Methoxybenzaldehyde(cas: 135-02-4Application In Synthesis of 2-Methoxybenzaldehyde)

2-Methoxybenzaldehyde(cas: 135-02-4) is used as a flavor agent in foods including nonalcoholic/alcoholic beverages, baked goods, chewing gum, confections, frozen dairy, fruit ices, hard/soft candy, instant coffee, tea, Jams, jellies, and milk products. It also has been used to obtain good enantioselectivities using Cu(OAc)(2)-bis(oxazolines) via hydrogen bonding in asymmetric Henry reaction.Application In Synthesis of 2-Methoxybenzaldehyde

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,European Journal of Medicinal Chemistry included an article by Sang, Zhipei; Wang, Keren; Zhang, Pengfei; Shi, Jian; Liu, Wenmin; Tan, Zhenghuai. COA of Formula: C8H8O2. The article was titled 《Design, synthesis, in-silico and biological evaluation of novel chalcone derivatives as multi-function agents for the treatment of Alzheimer’s disease》. The information in the text is summarized as follows:

A series of novel chalcone derivatives I [n = 3,4,5,6; R1 = 3,4-dihydro-1H-isoquinolin-2-yl, (4-benzyl-1-piperidyl)] and II [n = 3,4,6; R2 = 4-fluoro, 2-methoxy, 4-dimethylamino] were synthesized and evaluated as multifunctional agents for the treatment of AD. Among of these synthesized compounds, compound I [n = 4, R1 = 3,4-dihydro-1H-isoquinolin-2-yl] was a selective BuChE inhibitor (IC50 = 2.6 μM) and selective MAO-B inhibitor (IC50 = 5.3 μM), which were supported by docking study. Compound compound I [n = 4, R1 = 3,4-dihydro-1H-isoquinolin-2-yl] also showed good antioxidant activity and was a selective metal chelator, as well as a neuroprotectant. Moreover, compound compound I [n = 4, R1 = 3,4-dihydro-1H-isoquinolin-2-yl] could significantly inhibit self-induced and Cu2+-induced Aβ1-42 aggregation with 70.2% and 80.7% inhibition rate, resp. and could disaggregate Cu2+-induced Aβ1-42 aggregation (73.5%), the further TEM images observed provided rational explanation. Besides, compound I [n = 4, R1 = 3,4-dihydro-1H-isoquinolin-2-yl] displayed good PAMPA-BBB permeability and conformed to the Lipinski’s rule of five. Further, compound I [n = 4, R1 = 3,4-dihydro-1H-isoquinolin-2-yl] presented precognitive effect on scopolamine-induced memory impairment in-vivo assay. Therefore, compound I [n = 4, R1 = 3,4-dihydro-1H-isoquinolin-2-yl] might be a promising multifunctional hit compound for the treatment of AD and the further structure optimization are in progress. In addition to this study using 2-Methoxybenzaldehyde, there are many other studies that have used 2-Methoxybenzaldehyde(cas: 135-02-4COA of Formula: C8H8O2) was used in this study.

2-Methoxybenzaldehyde(cas: 135-02-4) is used as a flavor agent in foods including nonalcoholic/alcoholic beverages, baked goods, chewing gum, confections, frozen dairy, fruit ices, hard/soft candy, instant coffee, tea, Jams, jellies, and milk products. It also has been used to obtain good enantioselectivities using Cu(OAc)(2)-bis(oxazolines) via hydrogen bonding in asymmetric Henry reaction.COA of Formula: C8H8O2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2022,Gutierrez, Mario; Garcia, Eduardo; Monterde, Cristina; Sanchez, Felix; Douhal, Abderrazzak published an article in Physical Chemistry Chemical Physics. The title of the article was 《Modulating the spectroscopy and dynamics of a proton-transfer dye by functionalizing with phenyl groups》.COA of Formula: C8H8O2 The author mentioned the following in the article:

Mols. undergoing excited-state proton transfer (ESPT) reactions are among the most interesting systems from spectroscopic and photophys. viewpoints. These mols. can be further functionalized with electron donating or accepting groups, inducing intramol. charge transfer (ICT) events, which might be coupled to the ESIPT ones, conferring them with different spectroscopic and photophys. properties, which can be essential to implement the related materials in many key scientific and technol. fields. Here, authors report new benzimidazole derivatives that are functionalized with a Ph group, 2-(5,10-diphenyl-1H-phenanthro[9,10-d]imidazol-2-yl)phenol (DP-HPPI), and its methylated equivalent, 2-(2-methoxyphenyl)-5,10-diphenyl-1H-phenanthro[9,10-d]imidazole (DP-MPPI). The results prove that these mols. in solutions undergo an ultrafast ICT (400-700 fs) reaction. Addnl., DP-HPPI also undergoes a reversible ESIPT process in dichloromethane. However, this is precluded in acetonitrile due to the involvement of intermol. H-bonds in this solvent. These results provide key insights into the development of proton-transfer materials with bespoke spectral and photodynamical properties. In the experiment, the researchers used many compounds, for example, 2-Methoxybenzaldehyde(cas: 135-02-4COA of Formula: C8H8O2)

2-Methoxybenzaldehyde(cas: 135-02-4) is used as a flavor agent in foods including nonalcoholic/alcoholic beverages, baked goods, chewing gum, confections, frozen dairy, fruit ices, hard/soft candy, instant coffee, tea, Jams, jellies, and milk products. It also has been used to obtain good enantioselectivities using Cu(OAc)(2)-bis(oxazolines) via hydrogen bonding in asymmetric Henry reaction.COA of Formula: C8H8O2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Safety of 2-MethoxybenzaldehydeIn 2019 ,《Synthesis of new low-viscous sulfonic acid-functionalized ionic liquid and its application as a Bronsted liquid acid catalyst for the one-pot mechanosynthesis of 4H-pyrans through the ball milling process》 appeared in Journal of Molecular Liquids. The author of the article were Khaligh, Nader Ghaffari; Mihankhah, Taraneh; Johan, Mohd. Rafie. The article conveys some information:

In the present study, a new low-viscous sulfonic acid-functionalized ionic liquid (SAIL) viz. 4,4′-trimethylene-N,N’-sulfonic acid-dipiperidinium chloride was synthesized and characterized by FTIR, 1D and 2D NMR, and Mass spectra. Then, some properties of new SAIL were determined including pH, viscosity, d., and solubility in some common solvents. The catalytic activity of new SAIL was demonstrated for the one-pot mechanosynthesis of pyrano[4,3-b]pyrans, dihydropyrano[3,2-c]chromene and tetrahydrobenzo[b]pyrans using planetary ball mill under solvent-free conditions. This current mechanosynthesis methodol. for the synthesis of 4H-pyran-annulated heterocyclic scaffolds displays a combination of the synthetic virtues of conventional multi-component reaction with ecol. benefits and convenience of a simple mechanocatalytic procedure. New SAIL was easily recycled and reused several times with no significant loss of activity. After reading the article, we found that the author used 2-Methoxybenzaldehyde(cas: 135-02-4Safety of 2-Methoxybenzaldehyde)

2-Methoxybenzaldehyde(cas: 135-02-4) is found in cassia oil, cinnamon bark, and cinnamon bark oil. It is a clear colorless liquid with a strong aroma. It has been used to examine the acaricidal activity of Periploca sepium oil and its active component against Tyrophagus putrescentiae.Safety of 2-Methoxybenzaldehyde

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem