Category: 135-02-4

Reference of 2-MethoxybenzaldehydeIn 2019 ,《Pyranopyrazoles as efficient antimicrobial agents: Green, one pot and multicomponent approach》 appeared in Bioorganic Chemistry. The author of the article were Reddy, Guda Mallikarjuna; Garcia, Jarem Raul; Zyryanov, Grigory V.; Sravya, Gundala; Reddy, Nemallapudi Bakthavatchala. The article conveys some information:

Innovative therapeutic heterocycles having precisely thiadiazolyl-pyranopyrazole fragments were prepared by using the ecofriendly synthetic route. Entire compounds formed in quant. yields. All the composites tested for their antimicrobial effectiveness against four microbial, two beneficial fungi’s and accurately measured the min. inhibitory concentrations (MIC and MBC/MFC), along with some initial structure activity relationships (SARs) also discussed. From the biol. outcomes, the motif 6f provided an outstanding activity against all six pathogens. The possible presence of a nitro substituent on this composite may undoubtedly enhance the activity. In addition, amalgams 6d, 6g and 6l displayed promising antimicrobial results. This may be justified to the presence of electron capture group attached to the benzene ring, while the combinations 6j and 6k were zero effect towards all bacterial strains. The other compounds were excellent to low antimicrobial efficiency. The intriguing point was observed that all the active compounds had in common immense antibacterial effectiveness on Gram-neg. bacteria than Gram-pos. one and more antifungal activity on A. niger compare to other fungus. All things considered and suggested that this outstanding green synthetic approach is used to develop biol. active compounds On top of that, biol. results confirmed that these biol. energetic motifs suitable for addnl. preclin. examine with the aim of standing novel innovative drugs.2-Methoxybenzaldehyde(cas: 135-02-4Reference of 2-Methoxybenzaldehyde) was used in this study.

2-Methoxybenzaldehyde(cas: 135-02-4) is found in cassia oil, cinnamon bark, and cinnamon bark oil. It is a clear colorless liquid with a strong aroma. It has been used to examine the acaricidal activity of Periploca sepium oil and its active component against Tyrophagus putrescentiae.Reference of 2-Methoxybenzaldehyde

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The author of 《Synthesis, spectral properties and corrosion inhibition efficiency of new ethyl hydrogen [(methoxyphenyl) (methylamino) methyl] phosphonate derivatives: Experimental and theoretical investigation》 were Djenane, Meriem; Chafaa, Salah; Chafai, Nadjib; Kerkour, Rachida; Hellal, Abdelkader. And the article was published in Journal of Molecular Structure in 2019. Reference of 2-Methoxybenzaldehyde The author mentioned the following in the article:

Two new α-aminophosphonic acids, Et H [(2-methoxyphenyl)(methylamino) Me]phosphonate (2-EHMAP) and Et H [(3-methoxyphenyl)(methylamino) Me]phosphonate (3-EHMAP) were synthesized by the reaction between Methylamine, 2- or 3-Methoxybenzaldehyde and Diethylphosphite in THF solution with FeCl3. The structures of the title compounds were determined by UV-visible, FTIR, 1H, 13C, 31P NMR and MS spectra and confirmed by centesimal anal. Their inhibition efficiency on the corrosion of mild steel in 1 M HCl and 0.5M H2SO4 solutions was studied by weight loss, polarization curves and electrochem. impedance spectroscopy (EIS). The surface morphol. of XC38 simple was studied by SEM and Atomic Force Microscopy (AFM). Both mols. are mixed inhibitors and that their adsorptions on the surface of mild steel obey the Langmuir isotherm and that the 2-EHMAP exhibit better inhibition efficiency. Quantum chem. calculations were performed by using DFT to study the influence of mol. structure on the inhibition efficiency; theor. findings are in good accord with the exptl. observations. In the part of experimental materials, we found many familiar compounds, such as 2-Methoxybenzaldehyde(cas: 135-02-4Reference of 2-Methoxybenzaldehyde)

2-Methoxybenzaldehyde(cas: 135-02-4) is used as a flavor agent in foods including nonalcoholic/alcoholic beverages, baked goods, chewing gum, confections, frozen dairy, fruit ices, hard/soft candy, instant coffee, tea, Jams, jellies, and milk products. It also has been used to obtain good enantioselectivities using Cu(OAc)(2)-bis(oxazolines) via hydrogen bonding in asymmetric Henry reaction.Reference of 2-Methoxybenzaldehyde

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The author of 《Synthesis and Cardiotropic Activity of 1-(Methoxybenzyl)-4-{2-[(Methoxybenzyl)Amino]Ethyl}Piperazines》 were Mokrov, G. V.; Likhosherstov, A. M.; Barchukov, V. V.; Stolyaruk, V. N.; Tsorin, I. B.; Vititnova, M. B.; Rebeko, A. G.; Kryzhanovskii, S. A.; Gudasheva, T. A.. And the article was published in Pharmaceutical Chemistry Journal in 2019. Recommanded Product: 2-Methoxybenzaldehyde The author mentioned the following in the article:

A group of new 1-(methoxybenzyl)-4-{2-[(methoxybenzyl)amino]ethyl}piperazines I (R1 = R2 = R3 = R4 = H, OCH3) were synthesized. The relationship of the structure of the triazaalkane linker and the cardiotropic activity in a series of these compounds was compared with that of previously studied linear and cyclic methoxyphenyltriazaalkanes. The most active compound in the group was I (R1 = H; R2 = R3 = R4 = OCH3) with statistically significant antiarrhythmic activity in aconitine and CaCl2 arrhythmia models. The experimental part of the paper was very detailed, including the reaction process of 2-Methoxybenzaldehyde(cas: 135-02-4Recommanded Product: 2-Methoxybenzaldehyde)

2-Methoxybenzaldehyde(cas: 135-02-4) is found in cassia oil, cinnamon bark, and cinnamon bark oil. It is a clear colorless liquid with a strong aroma. It has been used to examine the acaricidal activity of Periploca sepium oil and its active component against Tyrophagus putrescentiae.Recommanded Product: 2-Methoxybenzaldehyde

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Product Details of 135-02-4In 2020 ,《H5BW12O40-Catalyzed syntheses of 1,4-dihydropyridines and polyhydroquinolines via Hantzsch reaction: Joint experimental and computational studies》 appeared in Journal of Molecular Structure. The author of the article were Momeni, Tayebeh; Heravi, Majid M.; Hosseinnejad, Tayebeh; Mirzaei, Masoud; Zadsirjan, Vahideh. The article conveys some information:

A series of polyhydroquinoline derivatives I [RR1 = C(O)CH2C(Me2)CH2; Ar = Ph, 4-OMeC6H4, 3-O2NC6H4, etc.] was effectively synthesized via Hantzsch reaction of benzaldehydes, Et acetoacetate, dimedone and ammonium acetate in high yields in the presence of catalytic amounts of a highly neg. charged borotungstic acid H5BW12O40 in refluxing EtOH under green and mild reaction conditions. This method was also used for the synthesis of 1,4-dihydropyridines I [R = CO2Et; R1 = Me] via reaction of benzaldehydes, Et acetoacetate and ammonium acetate. Borotungstic acid is a Keggin-type heteropoly acid with a higher neg. charge and strong Bronsted acidity. Moreover, a comparative mechanistical anal. of Hantzsch reaction was made based on the structural, thermodynamical and electronic properties along with the reaction pathway using d. functional theory (DFT) and quantum theory of atoms in mols. (QTAIM) approaches.2-Methoxybenzaldehyde(cas: 135-02-4Product Details of 135-02-4) was used in this study.

2-Methoxybenzaldehyde(cas: 135-02-4) is found in cassia oil, cinnamon bark, and cinnamon bark oil. It is a clear colorless liquid with a strong aroma. It has been used to examine the acaricidal activity of Periploca sepium oil and its active component against Tyrophagus putrescentiae.Product Details of 135-02-4

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《Synthesis, structural and anticorrosion properties of diethyl(methoxyphenyl(phenylamino)methyl)phosphonate derivatives: Experimental and theoretical study》 was published in Journal of Molecular Structure in 2020. These research results belong to Moumeni, Ouahiba; Chafaa, Salah; Kerkour, Rachida; Benbouguerra, Khalissa; Chafai, Nadjib. COA of Formula: C8H8O2 The article mentions the following:

The authors synthesized three di-Et (phenylamino) Me phosphonate derivatives: Diethyl(phenyl(phenylamino)methyl)phosphonate (DEPAMP), Diethyl(2-methoxyphenyl(phenylamino)methyl)phosphonate (o-DEPAMP), Diethyl(4-methoxyphenyl(phenylamino)methyl)phosphonate (p-DEPAMP), whose the yields were 92%, 86% and 88%, resp. After confirmation of their structures by UV-visible, FTIR and NMR spectroscopic methods, the synthesized compounds were studied as corrosion inhibitors of XC48 C steel in 1 mol L-1 HCl medium. P-DEPAMP is a better inhibitor in 10-3 mol L-1. Atomic Force Microscopy (AFM) was required for metallic surface characterization and the quantum chem. parameters were calculated using the D. Functional Theory (DFT) method. The adsorption energies of the inhibitors on Fe (110) surface in gas and aqueous phases were premeditated adopting the Mol. Dynamics Simulation (MDS) method. This study described the successful performance of these compounds in corrosion using weight loss measurements, Potentiodynamic Polarization and Electrochem. Impedance Spectroscopy (EIS), and discusses the correlation between exptl. and theor., presumed DFT and MDS finding. The adsorption studies on surface were in agreement with the Langmuir adsorption isotherm model. The effects of position of OCH3 group located at ortho and para or without in chem. structure of aminophosphonates on the corrosion inhibition efficiencies of the compounds were also studied. The experimental process involved the reaction of 2-Methoxybenzaldehyde(cas: 135-02-4COA of Formula: C8H8O2)

2-Methoxybenzaldehyde(cas: 135-02-4) is used as a flavor agent in foods including nonalcoholic/alcoholic beverages, baked goods, chewing gum, confections, frozen dairy, fruit ices, hard/soft candy, instant coffee, tea, Jams, jellies, and milk products. It also has been used to obtain good enantioselectivities using Cu(OAc)(2)-bis(oxazolines) via hydrogen bonding in asymmetric Henry reaction.COA of Formula: C8H8O2

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HPLC of Formula: 135-02-4In 2019 ,《1,1′-Butylenebis(3-sulfo-3H-imidazol-1-ium) hydrogensulfate: a versatile task-specific ionic liquid catalyst for the synthesis of 4H-pyran scaffolds through non-conventional process》 appeared in Monatshefte fuer Chemie. The author of the article were Khaligh, Nader Ghaffari; Ling, Ong Chiu; Mihankhah, Taraneh; Johan, Mohd Rafie; Ching, Juan Joon. The article conveys some information:

In the present study, the catalytic efficiency of 1,1′-butylenebis(3-sulfo-3H-imidazol-1-ium)hydrogensulfate (BBSI-HSO4) as a versatile sulfonic acid-functionalized ionic liquid was demonstrated for the one-pot mechanosynthesis of pyrano[4,3-b]-pyrans I (R = C6H5, 4-FC6H4, 2-MeOC6H4, etc.) using planetary ball mill at room temperature under solvent-free conditions. This efficient mechanosynthesis approach to the 4H-pyran scaffolds displays a combination of the structure-activity relationship of ionic liquids with ecol. benefits of a mechanocatalytic procedure. The ionic liquid was easily recycled and reused several times with no significant loss of its catalytic activity.2-Methoxybenzaldehyde(cas: 135-02-4HPLC of Formula: 135-02-4) was used in this study.

2-Methoxybenzaldehyde(cas: 135-02-4) is found in cassia oil, cinnamon bark, and cinnamon bark oil. It is a clear colorless liquid with a strong aroma. It has been used to examine the acaricidal activity of Periploca sepium oil and its active component against Tyrophagus putrescentiae.HPLC of Formula: 135-02-4

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In 2019,Angewandte Chemie, International Edition included an article by Ye, Fei; Berger, Florian; Jia, Hao; Ford, Joseph; Wortman, Alan; Boergel, Jonas; Genicot, Christophe; Ritter, Tobias. Recommanded Product: 2-Methoxybenzaldehyde. The article was titled 《Aryl Sulfonium Salts for Site-Selective Late-Stage Trifluoromethylation》. The information in the text is summarized as follows:

Incorporation of the CF3 group into arenes has found increasing importance in drug discovery. Herein, we report the first photoredox-catalyzed cross-coupling of aryl thianthrenium salts with a copper-based trifluoromethyl reagent, which enables a site-selective late-stage trifluoromethylation of arenes. The reaction proceeds with broad functional group tolerance, even for complex small mols. on gram scale. The method was further extended to produce pentafluoroethylated derivatives In the experiment, the researchers used 2-Methoxybenzaldehyde(cas: 135-02-4Recommanded Product: 2-Methoxybenzaldehyde)

2-Methoxybenzaldehyde(cas: 135-02-4) is used as a flavor agent in foods including nonalcoholic/alcoholic beverages, baked goods, chewing gum, confections, frozen dairy, fruit ices, hard/soft candy, instant coffee, tea, Jams, jellies, and milk products. It also has been used to obtain good enantioselectivities using Cu(OAc)(2)-bis(oxazolines) via hydrogen bonding in asymmetric Henry reaction.Recommanded Product: 2-Methoxybenzaldehyde

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,Journal of Molecular Structure included an article by Davarpanah, Jamal; Ghahremani, Mahboubeh; Najafi, Ozhan. Formula: C8H8O2. The article was titled 《Synthesis of 1,4-dihydropyridine and polyhydroquinoline derivatives via Hantzsch reaction using nicotinic acid as a green and reusable catalyst》. The information in the text is summarized as follows:

A rapid, efficient and eco-friendly protocol has been developed for the preparation of various 1,4-dihydropyridine and polyhydroquinoline derivatives in the presence of nicotinic acid as a green and dual catalyst under solvent-free conditions. In this reaction, nicotinic acid shows a highly catalytic nature, easy to handle procedure, short reaction time, recycle exploitation and excellent isolated yields. Furthermore, the 1H and 13C chem. shift and X-ray spectra values together with the structural parameters of 1,4-dihydropyridine and polyhydroquinoline have been computed and the scaled values have been compared with the corresponding exptl. NMR and X-ray spectra. As a result, the calculated 1H and 13C chem. shift and X-ray spectra show a good agreement with the exptl. results. In the experiment, the researchers used 2-Methoxybenzaldehyde(cas: 135-02-4Formula: C8H8O2)

2-Methoxybenzaldehyde(cas: 135-02-4) is used as a flavor agent in foods including nonalcoholic/alcoholic beverages, baked goods, chewing gum, confections, frozen dairy, fruit ices, hard/soft candy, instant coffee, tea, Jams, jellies, and milk products. It also has been used to obtain good enantioselectivities using Cu(OAc)(2)-bis(oxazolines) via hydrogen bonding in asymmetric Henry reaction.Formula: C8H8O2

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Ether – Wikipedia,
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《Bi2O3/FAp, a sustainable catalyst for synthesis of dihydro-[1,2,4]triazolo[1,5-a]pyrimidine derivatives through green strategy》 was published in Applied Organometallic Chemistry in 2020. These research results belong to Kerru, Nagaraju; Gummidi, Lalitha; Maddila, Surya Narayana; Bhaskaruni, Sandeep V. H. S.; Jonnalagadda, Sreekantha B.. HPLC of Formula: 135-02-4 The article mentions the following:

The bismuth loaded on fluorapatite (Bi2O3/FAp) proved to be an excellent catalyst for the synthesis of novel dihydro-[1,2,4]triazolo[1,5-a]pyrimidine derivatives I (R = 4-methoxyphenyl, 2-nitrophenyl, indol-3-yl, etc.; R1 = Me, NH2) via a three-component reaction involving the mixture of 1H-1,2,4-triazol-5-amine, Et cyanoacetate or Et acetoacetate, and different benzaldehydes RCHO in ethanol at room temperature The catalyst material was characterized by X-ray diffraction, Brunauer-Emmett-Teller surface area anal., Fourier-transform IR, SEM, energy-dispersive X-ray spectroscopy, and transmission electron microscopy techniques. The efficacy of Bi2O3/FAp as a heterogeneous catalyst was evaluated with the loading of different weight% of bismuth on FAp. The 2.5% bismuth on FAp performed extremely well as a catalyst with a high yield of products (92%-96%) in a short reaction time (25-35 min). The catalyst was recovered by simple filtration. It showed undiminished activity up to five runs. Simple work-up, room temperature reaction, short reaction time, high yields, no column chromatog., and good reusability of catalyst are the merits of the proposed protocol. In addition, this process offers 100% carbon efficiency and 98% atom economy with noteworthy fiscal and environmental benefits. In the experimental materials used by the author, we found 2-Methoxybenzaldehyde(cas: 135-02-4HPLC of Formula: 135-02-4)

2-Methoxybenzaldehyde(cas: 135-02-4) is used as a flavor agent in foods including nonalcoholic/alcoholic beverages, baked goods, chewing gum, confections, frozen dairy, fruit ices, hard/soft candy, instant coffee, tea, Jams, jellies, and milk products. It also has been used to obtain good enantioselectivities using Cu(OAc)(2)-bis(oxazolines) via hydrogen bonding in asymmetric Henry reaction.HPLC of Formula: 135-02-4

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Computed Properties of C8H8O2In 2019 ,《Synthesis of New 6-[4-(2-Fluorophenylpiperazin-1-yl)]-3(2H)-Pyridazinone-2-Acetyl-2- (Substituted benzal)Hydrazone Derivatives and Evaluation of Their Cytotoxic Effects in Liver and Colon Cancer Cell Lines》 appeared in Pharmaceutical Chemistry Journal. The author of the article were Ozdemir, Zeynep; Basak-Turkmen, Nese; Ayhan, Idris; Ciftci, Osman; Uysal, Mehtap. The article conveys some information:

In this study, seven new 3(2H)-pyridazinone derivatives I (R = H, 2-Cl, 4-NMe2, 4-Me, 4-Cl, 4-Br, 2-MeO) expected to show cytotoxic activity in liver and colon cancer cell lines were synthesized. Compounds I were tested on HEP3B (liver cancer) and HTC116 (colon cancer) cell lines for cytotoxicity by using MTS [3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium] proliferation assay. Human fibroblast cells were used as a safety control in these tests. Compound I (R = 2-Cl) was the most active agent with respect to HEP3B and HTC116 cell lines. In the experiment, the researchers used 2-Methoxybenzaldehyde(cas: 135-02-4Computed Properties of C8H8O2)

2-Methoxybenzaldehyde(cas: 135-02-4) is found in cassia oil, cinnamon bark, and cinnamon bark oil. It is a clear colorless liquid with a strong aroma. It has been used to examine the acaricidal activity of Periploca sepium oil and its active component against Tyrophagus putrescentiae.Computed Properties of C8H8O2

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Ether – Wikipedia,
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