Category: 135-02-4

Volpi, G.; Garino, C.; Fresta, E.; Casamassa, E.; Giordano, M.; Barolo, C.; Viscardi, G. published an article in 2021. The article was titled 《Strategies to increase the quantum yield: Luminescent methoxylated imidazo[1,5-a]pyridines》, and you may find the article in Dyes and Pigments.SDS of cas: 135-02-4 The information in the text is summarized as follows:

A series of methoxylated imidazo[1,5-a]pyridines is presented and their optical and electrochem. properties investigated and interpreted on the basis of d. functional theory calculations The photophys. properties are discussed in relation to the chem. structure. The key role of the 1,3 substitutions on the imidazo[1,5-a]pyridine nucleus on rotational barriers and on frontier MOs is discussed in relation to the exptl. hyperchromic effect, photoemission quantum yield and electrochem. properties. Depending on the position of the introduced methoxy substituents on the imidazo[1,5-a]pyridine nucleus, we are able to tune the Stokes shift and to increase the emission quantum yield from 22% to 50%. The results came from multiple reactions, including the reaction of 2-Methoxybenzaldehyde(cas: 135-02-4SDS of cas: 135-02-4)

2-Methoxybenzaldehyde(cas: 135-02-4) is used as a flavor agent in foods including nonalcoholic/alcoholic beverages, baked goods, chewing gum, confections, frozen dairy, fruit ices, hard/soft candy, instant coffee, tea, Jams, jellies, and milk products. It also has been used to obtain good enantioselectivities using Cu(OAc)(2)-bis(oxazolines) via hydrogen bonding in asymmetric Henry reaction.SDS of cas: 135-02-4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《Deuteration of Formyl Groups via a Catalytic Radical H/D Exchange Approach》 was published in ACS Catalysis in 2020. These research results belong to Zhang, Yueteng; Ji, Peng; Dong, Yue; Wei, Yongyi; Wang, Wei. Formula: C8H8O2 The article mentions the following:

H/D exchange at formyl groups represents the straightforward approach to C-1 deuterated aldehydes. This transformation has been recently realized by transition metal and NHC carbene catalysis. Mechanistically, all of these processes involve an ionic pathway. Herein, we report a distinct photoredox catalytic, visible light mediated neutral radical approach. Selective control of highly reactive acyl radical in the energy barrier surmountable, reversible reaction enables driving the formation of deuterated products when an excess of D2O is employed. The power of the H/D exchange process has been demonstrated for not only aromatic aldehydes but also aliphatic substrates, which have been difficult in transitional metal catalyzed H/D exchange reactions, and for selective late-stage deuterium incorporation into complex structures with uniformly high deuteration level (>90%). In the part of experimental materials, we found many familiar compounds, such as 2-Methoxybenzaldehyde(cas: 135-02-4Formula: C8H8O2)

2-Methoxybenzaldehyde(cas: 135-02-4) is used as a flavor agent in foods including nonalcoholic/alcoholic beverages, baked goods, chewing gum, confections, frozen dairy, fruit ices, hard/soft candy, instant coffee, tea, Jams, jellies, and milk products. It also has been used to obtain good enantioselectivities using Cu(OAc)(2)-bis(oxazolines) via hydrogen bonding in asymmetric Henry reaction.Formula: C8H8O2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《Facile synthesis of controllable graphene-co-shelled reusable Ni/NiO nanoparticles and their application in the synthesis of amines under mild conditions》 was written by Liu, Jianguo; Zhu, Yuting; Wang, Chenguang; Singh, Thishana; Wang, Nan; Liu, Qiying; Cui, Zhibing; Ma, Longlong. Application of 135-02-4 And the article was included in Green Chemistry in 2020. The article conveys some information:

The primary objective of many researchers in chem. synthesis is the development of recyclable and easily accessible catalysts. These catalysts should preferably be made from Earth-abundant metals and have the ability to be utilized in the synthesis of pharmaceutically important compounds Amines are classified as privileged compounds, and are used extensively in the fine and bulk chem. industries, as well as in pharmaceutical and materials research. In many laboratories and in industry, transition metal catalyzed reductive amination of carbonyl compounds is performed using predominantly ammonia and H2. However, these reactions usually require precious metal-based catalysts or RANEY nickel, and require harsh reaction conditions and yield low selectivity for the desired products. Herein, we describe a simple and environmentally friendly method for the preparation of thin graphene spheres that encapsulate uniform Ni/NiO nanoalloy catalysts (Ni/NiO@C) using nickel citrate as the precursor. The resulting catalysts are stable and reusable and were successfully used for the synthesis of primary, secondary, tertiary, and N-methylamines (more than 62 examples). The reaction couples easily accessible carbonyl compounds (aldehydes and ketones) with ammonia, amines, and H2 under very mild industrially viable and scalable conditions (80°C and 1 MPa H2 pressure, 4 h), offering cost-effective access to numerous functionalized, structurally diverse linear and branched benzylic, heterocyclic, and aliphatic amines including drugs and steroid derivatives We have also demonstrated the scale-up of the heterogeneous amination protocol to gram-scale synthesis. Furthermore, the catalyst can be immobilized on a magnetic stirring bar and be conveniently recycled up to five times without any significant loss of catalytic activity and selectivity for the product.2-Methoxybenzaldehyde(cas: 135-02-4Application of 135-02-4) was used in this study.

2-Methoxybenzaldehyde(cas: 135-02-4) is used as a flavor agent in foods including nonalcoholic/alcoholic beverages, baked goods, chewing gum, confections, frozen dairy, fruit ices, hard/soft candy, instant coffee, tea, Jams, jellies, and milk products. It also has been used to obtain good enantioselectivities using Cu(OAc)(2)-bis(oxazolines) via hydrogen bonding in asymmetric Henry reaction.Application of 135-02-4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,Polyhedron included an article by Zeynizadeh, Behzad; Rahmani, Soleiman; Ilkhanizadeh, Siamand. Application In Synthesis of 2-Methoxybenzaldehyde. The article was titled 《Strongly proton exchanged montmorillonite K10 (H+-Mont) as a solid acid catalyst for highly efficient and environmental benign synthesis of biscoumarins via tandem Knoevenagel-Michael reaction》. The information in the text is summarized as follows:

In this study, synthesis of micro/meso porous acid-activated montmorillonite K10 (H+-Mont) was carried out by the activation of Na+-montmorillonite with HCl (4 M) at the controlled conditions. The prepared H+-Mont clay was then characterized using FT-IR, SEM, EDX, XRD and BET analyses. SEM and BET surface analyses represented that by the acid-activation, adjacent layers of montmorillonite K10 (Mont K10) were exfoliated to tiny segments leading to raise of surface area and total pore volume in H+-Mont system rather than the alone Mont K10. Catalytic activity of the prepared H+-Mont clay was further studied as a potent solid acid catalyst for synthesis of biscoumarin materials via tandem Knoevenagel-Michael reaction of 4-hydroxycoumarin with aromatic aldehydes. All reactions were carried out in a mixture of H2O-EtOH (1:1) at room temperature to afford the products in high to excellent yields within 25-50 min. After reading the article, we found that the author used 2-Methoxybenzaldehyde(cas: 135-02-4Application In Synthesis of 2-Methoxybenzaldehyde)

2-Methoxybenzaldehyde(cas: 135-02-4) is used as a flavor agent in foods including nonalcoholic/alcoholic beverages, baked goods, chewing gum, confections, frozen dairy, fruit ices, hard/soft candy, instant coffee, tea, Jams, jellies, and milk products. It also has been used to obtain good enantioselectivities using Cu(OAc)(2)-bis(oxazolines) via hydrogen bonding in asymmetric Henry reaction.Application In Synthesis of 2-Methoxybenzaldehyde

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,Nature Catalysis included an article by Geng, Huihui; Chen, Xiaobei; Gui, Jingjing; Zhang, Yueteng; Shen, Zuyuan; Qian, Pengfei; Chen, Junwei; Zhang, Shilei; Wang, Wei. Formula: C8H8O2. The article was titled 《Practical synthesis of C1 deuterated aldehydes enabled by NHC catalysis》. The information in the text is summarized as follows:

N-heterocyclic carbenes promoted a reversible hydrogen-deuterium exchange reaction with simple aldehydes, which led to a practical approach to synthetically valuable C1 deuterated aldehydes RC(O)D [R = Ph, Bn, CH=CHPh, etc.]. The reactivity of the well-established N-heterocyclic carbene-catalyzed formation of Breslow intermediates from aldehydes was reengineered to overcome the overwhelmingly kinetically favorable benzoin condensation reaction and achieve the critical reversibility to drive the formation of desired deuterated products when an excess of D2O was employed. Notably, this operationally simple and cost-effective protocol served as a general and truly practical approach to all types of 1-D-aldehydes including aryl, alkyl and alkenyl aldehydes and enabled chemoselective late-stage deuterium incorporation into complex, native therapeutic agents and natural products with uniformly high levels (>95%) of deuterium incorporation for a total of 104 tested substrates. The experimental part of the paper was very detailed, including the reaction process of 2-Methoxybenzaldehyde(cas: 135-02-4Formula: C8H8O2)

2-Methoxybenzaldehyde(cas: 135-02-4) is used as a flavor agent in foods including nonalcoholic/alcoholic beverages, baked goods, chewing gum, confections, frozen dairy, fruit ices, hard/soft candy, instant coffee, tea, Jams, jellies, and milk products. It also has been used to obtain good enantioselectivities using Cu(OAc)(2)-bis(oxazolines) via hydrogen bonding in asymmetric Henry reaction.Formula: C8H8O2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,ChemistrySelect included an article by Mellado, Marco; Salas, Cristian O.; Uriarte, Eugenio; Vina, Dolores; Jara-Gutierrez, Carlos; Matos, Maria J.; Cuellar, Mauricio. Electric Literature of C8H8O2. The article was titled 《Design, Synthesis and Docking Calculations of Prenylated Chalcones as Selective Monoamine Oxidase B Inhibitors with Antioxidant Activity》. The information in the text is summarized as follows:

The synthesis of seven new prenylated chalcones I (R = Ph, 2-HOC6H4, 4-MeOC6H4, etc.) obtained from the natural compound, 4-hydroxy-3-(3-methylbut-2-en-1-yl)acetophenone, previously isolated from S. graveolens, is reported. Five of these compounds exhibited high inhibition and selectivity against MAO-B with IC50 values in the low micromolar range. In addition, the antioxidant activity of this series was measured, with three compounds showing a better activity than the reference, butylated hydroxytoluene (BHT). Compound I (R = 4-Me2NC6H4) proved to be the best compound within the studied series (IC50 MAO-B = 8.19 μM and k DPPH = 3.73). Finally, mol. docking was performed to better understand the binding properties of these derivatives Important features for MAO-B inhibitory activity observed were hydrogen-bonding interaction between Tyr435 and nearness with Tyr398 and FAD co-factor. Therefore, these mols. were good candidates for the design of a lead compound for Parkinson’s disease. In addition to this study using 2-Methoxybenzaldehyde, there are many other studies that have used 2-Methoxybenzaldehyde(cas: 135-02-4Electric Literature of C8H8O2) was used in this study.

2-Methoxybenzaldehyde(cas: 135-02-4) is used as a flavor agent in foods including nonalcoholic/alcoholic beverages, baked goods, chewing gum, confections, frozen dairy, fruit ices, hard/soft candy, instant coffee, tea, Jams, jellies, and milk products. It also has been used to obtain good enantioselectivities using Cu(OAc)(2)-bis(oxazolines) via hydrogen bonding in asymmetric Henry reaction.Electric Literature of C8H8O2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Yu, Weiwei; Hu, Zhiru; Fu, Xinyu; Li, Yanchun; Su, Junfeng; Yang, Ting; Li, Songrui; Song, Zhiguang; Feng, Guodong published an article in 2021. The article was titled 《Phenanthroline derivative fluorescent probe for rapid and sensitive detection of silver(I)》, and you may find the article in Analytical Sciences.Quality Control of 2-Methoxybenzaldehyde The information in the text is summarized as follows:

In the present work, a phenanthroline derivative (2-(2-methoxyphenyl)-4-phenyl-1,10-phenanthroline, MPP), as a fluorescent probe, was synthesized to realize a rapid, simple and sensitive detection of silver(I). The detection conditions of Ag+ were optimized. This fluorescent probe has the advantages of a fast reaction time, a wide pH applicable range, and a low detection limit, exhibiting a good linear response between the fluorescence intensity and the concentration in the range of 0.05 – 1.5 μmol/L for Ag+. The detection limit is as low as 3.38 x 10-8 mol/L (S/N = 3). This probe had been used to detect Ag+ in real samples, and the recovery efficiency of spiked Ag+ had been also tested. The recovery efficiency is satisfactory, ranging from 92.0 to 105.4%. Therefore, this fluorescent probe should provide a new choice for the quant. detection of silver ions in environmental water samples. In the part of experimental materials, we found many familiar compounds, such as 2-Methoxybenzaldehyde(cas: 135-02-4Quality Control of 2-Methoxybenzaldehyde)

2-Methoxybenzaldehyde(cas: 135-02-4) is found in cassia oil, cinnamon bark, and cinnamon bark oil. It is a clear colorless liquid with a strong aroma. It has been used to examine the acaricidal activity of Periploca sepium oil and its active component against Tyrophagus putrescentiae.Quality Control of 2-Methoxybenzaldehyde

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,ChemistrySelect included an article by Maddila, Suresh; Nagaraju, Kerru; Chinnam, Sampath; Jonnalagadda, Sreekantha B.. Electric Literature of C8H8O2. The article was titled 《Microwave-Assisted Multicomponent Reaction: A Green and Catalyst-Free Method for the Synthesis of Poly-Functionalized 1,4-Dihydropyridines》. The information in the text is summarized as follows:

A facile and an efficient procedure for the synthesis of poly-substituted 1,4-dihydropyridine derivatives under catalyst-free conditions was established by a one-pot multi-component reaction in EtOH solvent under microwave irradiation (150 W). The remarkable benefits of this approach were: simple operation, non-toxic, short reaction time (< 5 min), excellent yields (93-98%), no column chromatog., clean reaction profile and environmentally friendly reaction. In addition to this study using 2-Methoxybenzaldehyde, there are many other studies that have used 2-Methoxybenzaldehyde(cas: 135-02-4Electric Literature of C8H8O2) was used in this study.

2-Methoxybenzaldehyde(cas: 135-02-4) is used as a flavor agent in foods including nonalcoholic/alcoholic beverages, baked goods, chewing gum, confections, frozen dairy, fruit ices, hard/soft candy, instant coffee, tea, Jams, jellies, and milk products. It also has been used to obtain good enantioselectivities using Cu(OAc)(2)-bis(oxazolines) via hydrogen bonding in asymmetric Henry reaction.Electric Literature of C8H8O2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,Nature Communications included an article by Lv, Leiyang; Zhu, Dianhu; Li, Chao-Jun. Name: 2-Methoxybenzaldehyde. The article was titled 《Direct dehydrogenative alkyl Heck-couplings of vinylarenes with umpolung aldehydes catalyzed by nickel》. The information in the text is summarized as follows:

Herein, a nickel-catalyzed direct dehydrogenative alkyl Heck-coupling of vinylarenes with umpolung aldehydes to give alkenes under oxidant-free conditions, liberating hydrogen, nitrogen and water as the side products was presented. Excellent regioselectivity was achieved via neighboring oxygen atom coordination. Broad substrate scope, great functional group (ketone, ester, phenol, free amine, amide etc.) tolerance and modification of pharmaceutical candidates and biol. mols. exemplified its generality and practicability. After reading the article, we found that the author used 2-Methoxybenzaldehyde(cas: 135-02-4Name: 2-Methoxybenzaldehyde)

2-Methoxybenzaldehyde(cas: 135-02-4) is used as a flavor agent in foods including nonalcoholic/alcoholic beverages, baked goods, chewing gum, confections, frozen dairy, fruit ices, hard/soft candy, instant coffee, tea, Jams, jellies, and milk products. It also has been used to obtain good enantioselectivities using Cu(OAc)(2)-bis(oxazolines) via hydrogen bonding in asymmetric Henry reaction.Name: 2-Methoxybenzaldehyde

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《Facile One-pot Synthesis of Arylsulfonyl-4H-pyrans Catalyzed by Ru Loaded Fluorapatite》 was published in ChemistrySelect in 2020. These research results belong to Maddila, Surya N.; Maddila, Suresh; Kerru, Nagaraju; Bhaskaruni, Sandeep V. H. S.; Jonnalagadda, Sreekantha B.. Name: 2-Methoxybenzaldehyde The article mentions the following:

A novel ecofriendly cascade reaction for the synthesis of arylsulfonyl-4H-pyran derivatives by a three component fusion reaction of chosen aldehyde, dimedone and phenylsulfonyl acetonitrile at room temperature using ruthenia doped fluorapatite (RuO2/FAp) as recyclable catalyst is reported. Different percentages of RuO2/FAp materials were prepared and characterized by FT-IR, P-XRD, BET, SEM-EDX and TEM anal. Attractive features of the synthetic approach are operational simplicity, cost-effectiveness, short reaction time and excellent yields. Easily recoverable and reusable catalyst material without any deceptive loss of catalytic activity up to seven cycles is addnl. benefit. In the experiment, the researchers used 2-Methoxybenzaldehyde(cas: 135-02-4Name: 2-Methoxybenzaldehyde)

2-Methoxybenzaldehyde(cas: 135-02-4) is used as a flavor agent in foods including nonalcoholic/alcoholic beverages, baked goods, chewing gum, confections, frozen dairy, fruit ices, hard/soft candy, instant coffee, tea, Jams, jellies, and milk products. It also has been used to obtain good enantioselectivities using Cu(OAc)(2)-bis(oxazolines) via hydrogen bonding in asymmetric Henry reaction.Name: 2-Methoxybenzaldehyde

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem