Category: 135-02-4

The author of 《Ionic-Liquid-Modified Porous Au/CeMnOx Nanorods for Methyl Methacrylate (MMA) Synthesis via Direct Oxidative Esterification》 were Tian, Yun; Li, Yuchao; Zuo, Cuncun; Yin, Defeng; Wang, Ling; Zheng, Yanxia; Huang, Haofei; Fu, Zhongjun; Wang, Ming. And the article was published in ChemNanoMat in 2019. Synthetic Route of C8H8O2 The author mentioned the following in the article:

Porous MnCeOx solid solutions nanorods (PN-MnCeOx) with different pore sizes were prepared using different carbon chain lengths ionic liquids (C10mimCl, C12mimCl and C14mimCl). Series of novel catalysts with nano-Au supported on the PN-MnCeOx, were synthesized and applied to oxidative esterification of benzaldehydes to esters. Catalytic performance was evaluated in batch reactor and the relatively optimum catalyst was screened out. Kinds of characterization methods, such as XRD, TEM, XPS and BET, were applied to analyze crystal plane, microstructure, sp. surface area, and porous structure of the catalysts and the structure-activity relationship could be reasonably explained. The cyclic stability of the catalyst was also tested more than 7 times using MAL and methanol for Me methacrylate synthesis via one step oxidative esterification. In the part of experimental materials, we found many familiar compounds, such as 2-Methoxybenzaldehyde(cas: 135-02-4Synthetic Route of C8H8O2)

2-Methoxybenzaldehyde(cas: 135-02-4) is used as a flavor agent in foods including nonalcoholic/alcoholic beverages, baked goods, chewing gum, confections, frozen dairy, fruit ices, hard/soft candy, instant coffee, tea, Jams, jellies, and milk products. It also has been used to obtain good enantioselectivities using Cu(OAc)(2)-bis(oxazolines) via hydrogen bonding in asymmetric Henry reaction.Synthetic Route of C8H8O2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《One-Pot Three-Component Synthesis of 2,4,5-Triaryl-1H-imidazoles in the Presence of a Molecular Sieve Supported Titanium Catalyst under Mild Basic Conditions》 was written by Magyar, Agnes; Hell, Zoltan. Electric Literature of C8H8O2This research focused ontriaryl imidazole one pot three component preparation titanium catalyst; titanium mol sieve supported catalyst. The article conveys some information:

A series of 2,4,5-trisubstituted-imidazoles was synthesized with good to excellent yields by the one-pot condensation reaction of 1,2-dicarbonyl compounds, benzaldehydes, and ammonium acetate in the presence of 4 Å mol. sieves modified with titanium(IV) as an efficient heterogeneous catalyst. The catalyst could be recovered easily and reused without significant loss of activity. The experimental part of the paper was very detailed, including the reaction process of 2-Methoxybenzaldehyde(cas: 135-02-4Electric Literature of C8H8O2)

2-Methoxybenzaldehyde(cas: 135-02-4) is found in cassia oil, cinnamon bark, and cinnamon bark oil. It is a clear colorless liquid with a strong aroma. It has been used to examine the acaricidal activity of Periploca sepium oil and its active component against Tyrophagus putrescentiae.Electric Literature of C8H8O2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Application In Synthesis of 2-MethoxybenzaldehydeIn 2019 ,《Preparation and characterization of an eco-friendly ZnFe2O4@alginic acid nanocomposite catalyst and its application in the synthesis of 2-amino-3-cyano-4H-pyran derivatives》 appeared in Polyhedron. The author of the article were Maleki, Ali; Varzi, Zahra; Hassanzadeh-Afruzi, Fereshte. The article conveys some information:

The ZnFe2O4@alginic acid nanocomposite was synthesized by a simple procedure. Then, it was utilized as a green, cost-effective and heterogeneous catalyst in the synthesis of 2-amino-3-cyano-4H-pyran derivatives I (R = H, 2-NO2, 3-MeO, 4-OH, etc.) with a one-pot three-component reaction between various aromatic aldehydes RC6H4CHO, dimedone and malononitrile. Conventional methods such as Fourier transform IR (FT-IR) spectroscopy, X-ray diffraction (XRD) pattern, SEM (SEM) image, energy-dispersive X-ray (EDX) anal., vibrating sample magnetometer (VSM) curve and inductively-coupled plasma at. emission spectroscopy (ICP-AES) anal. were employed to characterize the prepared nanocomposite. This protocol offers some beneficial features such as green catalyst, mild reaction conditions, simple procedure, easy workup, short reaction times and significant yield of the products I. The magnetic properties of the nanocomposite caused its easy separation by using an external magnetic field from the reaction mixture without significant loss of its catalytic activity. In the experiment, the researchers used many compounds, for example, 2-Methoxybenzaldehyde(cas: 135-02-4Application In Synthesis of 2-Methoxybenzaldehyde)

2-Methoxybenzaldehyde(cas: 135-02-4) is found in cassia oil, cinnamon bark, and cinnamon bark oil. It is a clear colorless liquid with a strong aroma. It has been used to examine the acaricidal activity of Periploca sepium oil and its active component against Tyrophagus putrescentiae.Application In Synthesis of 2-Methoxybenzaldehyde

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

The author of 《Monodentate Transient Directing Group Enabled Pd-Catalyzed Ortho-C-H Methoxylation and Chlorination of Benzaldehydes》 were Li, Feng; Zhou, Yirong; Yang, Heng; Wang, Ziqi; Yu, Qinqin; Zhang, Fang-Lin. And the article was published in Organic Letters in 2019. Synthetic Route of C8H8O2 The author mentioned the following in the article:

We report Pd-catalyzed ortho-C-H methoxylation and chlorination of benzaldehydes by employing monodentate transient directing groups (TDGs) as an alternative strategy to bidentate TDGs. More importantly, a single crystal of benzaldehyde imine ortho-cyclopalladium intermediate was successfully obtained, and its structure was unambiguously determined by X-ray diffraction, which clearly showed that it was a binuclear palladium species bridged by a pyridone ligand. The utility of this approach was further demonstrated through the synthesis of key intermediates of natural products and drugs. In the experiment, the researchers used many compounds, for example, 2-Methoxybenzaldehyde(cas: 135-02-4Synthetic Route of C8H8O2)

2-Methoxybenzaldehyde(cas: 135-02-4) is found in cassia oil, cinnamon bark, and cinnamon bark oil. It is a clear colorless liquid with a strong aroma. It has been used to examine the acaricidal activity of Periploca sepium oil and its active component against Tyrophagus putrescentiae.Synthetic Route of C8H8O2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《In-vitro and in-silico evaluations of heterocyclic-containing diarylpentanoids as Bcl-2 inhibitors against LoVo colorectal cancer cells》 was published in Molecules in 2020. These research results belong to Leong, Sze Wei; Chia, Suet Lin; Abas, Faridah; Yusoff, Khatijah. Computed Properties of C8H8O2 The article mentions the following:

In the present study, we investigated the in-vitro anti-cancer potential of six diarylpentanoids against a panel of BRAF- and KRAS-mutated colorectal cancer cell lines including T84, SW620, LoVo, HT29, NCI-H508, RKO, and LS411N cells. Structure-activity relationship study suggested that the insertions of tetrahydro-4H-thiopyran-4-one and brominated Ph moieties are essential for better cytotoxicity. Among the evaluated analogs, 2e has been identified as the lead compound due to its low IC50 values of approx. 1μM across all cancer cell lines and high chemotherapeutic index of 7.1. Anti-proliferative studies on LoVo cells showed that 2e could inhibit cell proliferation and colony formations by inducing G2/M cell cycle arrest. Subsequent cell apoptosis assay confirmed that 2e is a Bcl-2 inhibitor that could induce intrinsic cell apoptosis by creating a cellular redox imbalance through its direct inhibition on the Bcl-2 protein. Further mol. docking studies revealed that the bromophenyl moieties of 2e could interact with the Bcl-2 surface pocket through hydrophobic interaction, while the tetrahydro-4H-thiopyran-4-one fragment could form addnl. Pi-sulfur and Pi-alkyl interactions in the same binding site. In all, the present results suggest that 2e could be a potent lead that deserves further modification and investigation in the development of a new Bcl-2 inhibitor.2-Methoxybenzaldehyde(cas: 135-02-4Computed Properties of C8H8O2) was used in this study.

2-Methoxybenzaldehyde(cas: 135-02-4) is used as a flavor agent in foods including nonalcoholic/alcoholic beverages, baked goods, chewing gum, confections, frozen dairy, fruit ices, hard/soft candy, instant coffee, tea, Jams, jellies, and milk products. It also has been used to obtain good enantioselectivities using Cu(OAc)(2)-bis(oxazolines) via hydrogen bonding in asymmetric Henry reaction.Computed Properties of C8H8O2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Synthetic Route of C8H8O2In 2019 ,《One-pot synthesis of 2-amino-4H-chromene derivatives by MNPs@Cu as an effective and reusable magnetic nanocatalyst》 was published in RSC Advances. The article was written by Ma, Wanzheng; Ebadi, Abdol Ghaffar; sabil, Mostafa shahbazi; Javahershenas, Ramin; Jimenez, Giorgos. The article contains the following contents:

In this research, MNPs@Cu as an effective and recyclable nanocatalyst was prepared and characterized using different methods including FT-IR, TGA, VSM, SEM, EDX and XRD. After the characterization of this new nanocatalyst, it was efficiently used for one-pot synthesis of 2-amino-4H-chromene derivatives I [R = Ph, 4-MeOC6H4, 4-ClC6H4, etc.], II and III [X = NH, O] via one-pot three-component Knoevenagel condensation of enolizable compounds, malononitrile and benzaldehydes under solvent-free conditions. The procedure gave the desired products I, II and III in high-to-excellent yields in short reaction times. Also this catalyst, because of its magnetic nature, could be simply restored by a permanent magnetic field and comfortably reused several times without any significant loss of its catalytic activity. The results came from multiple reactions, including the reaction of 2-Methoxybenzaldehyde(cas: 135-02-4Synthetic Route of C8H8O2)

2-Methoxybenzaldehyde(cas: 135-02-4) is found in cassia oil, cinnamon bark, and cinnamon bark oil. It is a clear colorless liquid with a strong aroma. It has been used to examine the acaricidal activity of Periploca sepium oil and its active component against Tyrophagus putrescentiae.Synthetic Route of C8H8O2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Application of 135-02-4In 2020 ,《Ag nanoparticles stabilized on cyclodextrin polymer decorated with multi-nitrogen atom containing polymer: an efficient catalyst for the synthesis of xanthenes》 was published in Molecules. The article was written by Sadjadi, Samahe; Kahangi, Fatemeh Ghoreyshi; Dorraj, Masoumeh; Heravi, Majid M.. The article contains the following contents:

In attempt to broaden the use of cyclodextrin polymer for catalytic purposes, a novel covalent hybrid system was prepared through growth of multi-nitrogen atom containing polymer (PMelamine) derived from reaction of ethylenediamine and 2,4,6-trichloro-1,3,5-triazine on the functionalized cyclodextrin polymer (CDNS). The resulting hybrid system was then utilized as a catalyst support for the immobilization of silver nanoparticles through using Cuscuta epithymum extract as a naturally-derived reducing agent. The catalytic activity of the catalyst,Ag@CDNS-N/PMelamine, for the synthesis of xanthenes through reaction of aldehydes and dimedone in aqueous media was examined The results showed high catalytic activity and recyclability of the catalyst. It was believed that cyclodextrin in the backbone of the catalyst could act both as a capping agent for Ag nanoparticles and phase transfer agent to bring the hydrophobic substrates in the vicinity of the catalytic active sites and accelerate the reaction rate. Multi-nitrogen atoms on the polymer, on the other hand, could improve the Ag NPs anchoring and suppress their leaching. In the experimental materials used by the author, we found 2-Methoxybenzaldehyde(cas: 135-02-4Application of 135-02-4)

2-Methoxybenzaldehyde(cas: 135-02-4) is found in cassia oil, cinnamon bark, and cinnamon bark oil. It is a clear colorless liquid with a strong aroma. It has been used to examine the acaricidal activity of Periploca sepium oil and its active component against Tyrophagus putrescentiae.Application of 135-02-4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Wu, Yongdi; Liu, Na; Qi, Meifang; Qiao, Huihao; Lu, Xuelian; Ma, Li; Zhou, Yirong; Zhang, Fang-Lin published their research in Organic Letters in 2021. The article was titled 《Monodentate Transient Directing Group Assisted Ruthenium(II)-Catalyzed Direct ortho-C-H Imidation of Benzaldehydes for Diverse Synthesis of Quinazoline and Fused Isoindolinone》.Related Products of 135-02-4 The article contains the following contents:

2-Fluoro-5-(trifluoromethyl)aniline was found to be a suitable monodentate transient directing group (MonoTDG) to enable Ru(II)-catalyzed intermol. direct ortho-C(sp2)-H imidation of benzaldehydes. N-Tosyloxyphthalimide was used as an alternative azide-free amidation reagent to achieve high efficiency and good functional group tolerance. Moreover, the reaction could be enlarged to gram scale, and the amidated product could be readily converted into useful quinazoline and fused isoindolinone scaffolds by one-step derivatization. In the part of experimental materials, we found many familiar compounds, such as 2-Methoxybenzaldehyde(cas: 135-02-4Related Products of 135-02-4)

2-Methoxybenzaldehyde(cas: 135-02-4) is used as a flavor agent in foods including nonalcoholic/alcoholic beverages, baked goods, chewing gum, confections, frozen dairy, fruit ices, hard/soft candy, instant coffee, tea, Jams, jellies, and milk products. It also has been used to obtain good enantioselectivities using Cu(OAc)(2)-bis(oxazolines) via hydrogen bonding in asymmetric Henry reaction.Related Products of 135-02-4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

The author of 《Fe3O4/SO3H@zeolite-Y as a novel multi-functional and magnetic nanocatalyst for clean and soft synthesis of imidazole and perimidine derivatives》 were Kalhor, Mehdi; Zarnegar, Zohre. And the article was published in RSC Advances in 2019. Recommanded Product: 135-02-4 The author mentioned the following in the article:

In this study, SO3H@zeolite-Y was synthesized by the reaction of chlorosulfonic acid with zeolite-NaY under solvent-free conditions, which was then supported by Fe3O4 nanoparticles to give SO3H@zeolite-Y (Fe3O4/SO3H@zeolite-Y) magnetic nanoparticles. Several techniques were used to evaluate the phys. and chem. characterizations of the zeolitic nanostructures. Fe3O4-loaded sulfonated zeolite was applied as a novel multi-functional zeolite catalyst for the synthesis of imidazole and perimidine derivatives This efficient methodol. has some advantages such as good to excellent yield, high purity of products, reusability of nanocatalyst, simple reaction conditions, environmental friendliness and an economical chem. procedure from the viewpoint of green chem. In the experiment, the researchers used 2-Methoxybenzaldehyde(cas: 135-02-4Recommanded Product: 135-02-4)

2-Methoxybenzaldehyde(cas: 135-02-4) is used as a flavor agent in foods including nonalcoholic/alcoholic beverages, baked goods, chewing gum, confections, frozen dairy, fruit ices, hard/soft candy, instant coffee, tea, Jams, jellies, and milk products. It also has been used to obtain good enantioselectivities using Cu(OAc)(2)-bis(oxazolines) via hydrogen bonding in asymmetric Henry reaction.Recommanded Product: 135-02-4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,Organic Letters included an article by Huang, Jie; Ding, Jun; Ding, Tong-Mei; Zhang, Shuiyi; Wang, Yaqiu; Sha, Feng; Zhang, Shu-Yu; Wu, Xin-Yan; Li, Qiong. Electric Literature of C8H8O2. The article was titled 《Cobalt-Catalyzed Ortho-C(sp2)-H Amidation of Benzaldehydes with Dioxazolones Using Transient Directing Groups》. The information in the text is summarized as follows:

An efficient and convenient cobalt-catalyzed ortho-C(sp2)-H amidation of benzaldehydes employing dioxazolones as the aminating reagent has been developed. The key feature of this protocol is the use of green and economic earth-abundant metals cobalt as the catalyst with the p-chloroaniline as the transient directing group. Further application of our approach was demonstrated by the synthesis of C1r serine protease inhibitor 45 (I) and elastase inhibitor 49 (II). In addition to this study using 2-Methoxybenzaldehyde, there are many other studies that have used 2-Methoxybenzaldehyde(cas: 135-02-4Electric Literature of C8H8O2) was used in this study.

2-Methoxybenzaldehyde(cas: 135-02-4) is used as a flavor agent in foods including nonalcoholic/alcoholic beverages, baked goods, chewing gum, confections, frozen dairy, fruit ices, hard/soft candy, instant coffee, tea, Jams, jellies, and milk products. It also has been used to obtain good enantioselectivities using Cu(OAc)(2)-bis(oxazolines) via hydrogen bonding in asymmetric Henry reaction.Electric Literature of C8H8O2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem