Category: 134-96-3

Homann, Julia published the artcileDevelopment of a Method for Anodic Degradation of Lignin for the Analysis of Paleo-Vegetation Proxies in Speleothems, Computed Properties of 134-96-3, the publication is ChemElectroChem (2022), 9(6), e202101312, database is CAplus.

Here we present an electrochem. method for the anodic oxidation and subsequent degradation of lignin in speleothems to utilize the resulting lignin oxidation products (LOPs) as paleo-vegetation markers. LOPs were analyzed using an ultra-high performance liquid chromatog. (UHPLC) system coupled to a high-resolution mass spectrometer (HRMS). The method presented here achieved comparable or even higher LOP concentrations than established CuO and CuSO₄ oxidation methods. The method represents a new tool for the anal. and reconstruction of paleo-vegetation and has the potential to be applied to other climate archives.

ChemElectroChem published new progress about 134-96-3. 134-96-3 belongs to ethers-buliding-blocks, auxiliary class Immunology/Inflammation,COX,Natural product, name is 4-Hydroxy-3,5-dimethoxybenzaldehyde, and the molecular formula is C9H10O4, Computed Properties of 134-96-3.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Dai, Guohua published the artcilePlant-derived lipids play a crucial role in forest soil carbon accumulation, Formula: C9H10O4, the publication is Soil Biology & Biochemistry (2022), 108645, database is CAplus.

Plant and microbial residues are two main sources of soil organic carbon (SOC). While recent studies have extensively examined the distribution of microbial necromass in different ecosystems, how plant residues (in particular, non-lignin components) contribute to SOC accumulation is less clear, especially in forests which make up 50% of the global soil carbon storage. Filling this knowledge gap will help us better understand SOC accumulation patterns and their response to land-use changes. Here, we analyze plant- and microbial-derived biomarkers (including lignin phenols, amino sugars, free and hydrolysable lipids) in the topsoil of major forest types in China and compare their distribution patterns together with the existing data (for lignin phenols and amino sugars) in forests and grasslands distributed globally. At the global scale, forests contain significantly less microbial necromass in SOC compared with grasslands, suggesting higher contribution of plant-derived components to forest SOC. However, plant-derived lignin phenols do not seem to play a major role in SOC accumulation, given their neg. relationship with SOC contents. Instead, leaf- and root-derived hydrolysable lipids constitute a much higher proportion of SOC than lignin phenols in the investigated forests of China, even compared to grassland soils. Moreover, in contrast to lignin phenols, both SOC contents and the relative abundance of hydrolysable plant lipids in SOC increase with decreasing soil pH, increasing reactive iron and aluminum contents and with increasing lignin oxidation (indicated by acid-to-aldehyde ratios) in these forest soils. These results suggest that with increasing lignin decomposition, plant lipids and SOC accumulated via (oxyhydr)oxide protection. Collectively, our results demonstrate differential importance of plant-derived components in SOC accumulation in forests vs. grasslands and highlight that plant lipids play a more important part than lignin in forest SOC accumulation. Quant. investigations on the distribution of plant-derived lipids in addition to lignin in forest soils may help to elucidate pathways and hotspots of plant component-dominated SOC accrual.

Soil Biology & Biochemistry published new progress about 134-96-3. 134-96-3 belongs to ethers-buliding-blocks, auxiliary class Immunology/Inflammation,COX,Natural product, name is 4-Hydroxy-3,5-dimethoxybenzaldehyde, and the molecular formula is C9H10O4, Formula: C9H10O4.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Feng, Chengqi published the artcileAcidolysis mechanism of lignin from bagasse during p-toluenesulfonic acid treatment, SDS of cas: 134-96-3, the publication is Industrial Crops and Products (2022), 114374, database is CAplus.

Lignin was efficiently separated from lignocellulosic biomass using p-toluenesulfonic acid (p-TsOH) treatment. However, lignin depolymerization and acidolysis have not been studied to date. In this study, the mechanism of lignin acidolysis was investigated. The structure of lignin in bagasse before and after the p-TsOH treatment was analyzed. The efficiency and selectivity of lignin depolymerization were evaluated. The lignin removal rate reached 88.81%. Hemicellulose was completely removed from lignin, and cellulose destruction was inhibited. The structure of lignin in bagasse was analyzed using NMR. The results revealed that α-methoxylated β-O-4 intermediates were formed during lignin depolymerization This indicated that the benzyl ether bonds were effectively catalyzed and broke, thereby promoting lignin dissolution The lignin-carbohydrate complex structure was destroyed. The insoluble and soluble lignin in the hydrolyzate were analyzed using NMR and gas chromatog.-mass spectrometry. The results indicated that the catalyst promoted breaking of the C_β-O bonds in the β-O-4 structures. Phenols and Hibbert ketones were formed. In addition, lignin sulfonation was confirmed by the presence of di-o-tolusulfone and di-p-tolusulfone. The low contents of β-β and β-5 bonds in the reaction products indicated that lignin condensation was inhibited. The results demonstrated that lignin acidolysis was synergistically catalyzed by H⁺ and p-TsOH. It provides important theor. support for efficient and clean separation of lignin using the p-TsOH treatment.

Industrial Crops and Products published new progress about 134-96-3. 134-96-3 belongs to ethers-buliding-blocks, auxiliary class Immunology/Inflammation,COX,Natural product, name is 4-Hydroxy-3,5-dimethoxybenzaldehyde, and the molecular formula is C9H10O4, SDS of cas: 134-96-3.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Yu, Haiyan published the artcileComprehensive two-dimensional gas chromatography mass spectrometry-based untargeted metabolomics to clarify the dynamic variations in the volatile composition of Huangjiu of different ages, Application of 4-Hydroxy-3,5-dimethoxybenzaldehyde, the publication is Journal of Food Science (2022), 87(4), 1563-1574, database is CAplus and MEDLINE.

Aging plays an important role in the formation of aroma characteristics of Huangjiu, a traditional Chinese alc. beverage. Comprehensive two-dimensional gas chromatog. mass spectrometry (GCxGC-qMS)-based untargeted metabolomics combined with a multivariate anal. was used to investigate the dynamic variations in the aroma profile of Huangjiu during aging process and to establish the relationship between the changing volatile metabolite profiles and the age-dependent sensory attributes. A total of 144 volatile metabolites were identified by GCxGC-qMS and 63 were selected as critical metabolites based on variable importance in projection values and p-values. Based on the results of principal component anal., orthogonal partial least-squares discriminant anal., and hierarchical clustering anal., the samples of six different ages were divided into three groups: 1Y and 3Y samples, 5Y and 8Y samples, and 10Y and 15Y samples. The partial least-squares anal. results further revealed the relationship between the aromas attributes and variations of these volatile compounds The high esters, aldehydes, and lactones contents contributed to the high intensities of the sweet and ester aroma attributes of the aged Huangjiu, while the high alcs. and Et esters contents contributed to the alc. and fruity aroma attributes of the newly brewed Huangjiu. These results improve our understanding of the chem. nature of the aroma characteristics of aged Huangjiu. Huangjiu is often labeled with its age as a measure of quality, which influences consumers’ choice. Dynamic variations in volatile compounds of Huangjiu during aging and its contribution to the aroma characteristics of Huangjiu were figured out, which will assist the industry to produce better quality aged Huangjiu for consumers.

Journal of Food Science published new progress about 134-96-3. 134-96-3 belongs to ethers-buliding-blocks, auxiliary class Immunology/Inflammation,COX,Natural product, name is 4-Hydroxy-3,5-dimethoxybenzaldehyde, and the molecular formula is C15H14O3, Application of 4-Hydroxy-3,5-dimethoxybenzaldehyde.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Hu, Boqin published the artcileEthanol extracts of Rhaponticum uniflorum (L.) DC flowers attenuate doxorubicin-induced cardiotoxicity via alleviating apoptosis and regulating mitochondrial dynamics in H9c2 cells, COA of Formula: C9H10O4, the publication is Journal of Ethnopharmacology (2022), 114936, database is CAplus and MEDLINE.

Loulu flowers (LLF) is the inflorescence of Rhaponticum uniflorum (L.) DC. (R. uniflorum), a member of the Compositae family. This plant possesses heat-clearing properties, detoxification effects, and is therefore frequently used for the treatment of cardiovascular diseases. Aim of this study: This study aimed to investigate the cardioprotective effects of ethanol extracts of LLF against doxorubicin (DOX)-induced cardiotoxicity and explore the associated mechanisms. Ethanol extracts of LLF were prepared and analyzed by LC-ESI-MS/MS. DOX-treated H9c2 cells and DOX-treated zebrafish models were used to explore the cardioprotective effect of ethanol extracts on myocardial function. The effects of LLF on DOX-induced cytotoxicity in H9c2 cells were investigated by MTT assay. Reactive Oxygen Species (ROS) levels, mitochondrial membrane potential (MMP), and nuclear translocation of NF-κB p65 were examined using fluorescent probes. The expression level of Bax, Bcl-2, PARP, caspase-3, cleaved-caspase3, caspase9, IκBα, p-IκBα, IKK, p-IKK, p65, p-p65, OPA1, Mfn1, MFF and Fis 1 and GAPDH was determined by western blotting. Twenty-five compounds were detected in ethanol extracts of LLF, include Nicotinamide, Coumarin, Parthenolide, and Ligustilide. Pre-treatment with LLF attenuated the DOX-induced decrease in viability and ROS production in H9c2 cells. Moreover, LLF treatment maintained the mitochondrial membrane integrity and suppressed apoptosis by upregulating expression level of Bcl-2 and downregulating the expression level of Bax, cleaved-caspase-3, cleaved-caspase-9 and cleaved-PARP. In addition, LLF significantly inhibited the DOX-induced activation of NF-κB signaling. Cells treated with DOX showed aberrant expression of mitochondrial dynamics related proteins, and these effects were alleviated by LLF pre-treatment. In conclusion, these results show that LLF can alleviate DOX-induced cardiotoxicity by blocking NF-κB signaling and re-balancing mitochondrial dynamics. Ethanol extracts of LLF is a potential treatment option to against DOX-induced cardiotoxicity.

Journal of Ethnopharmacology published new progress about 134-96-3. 134-96-3 belongs to ethers-buliding-blocks, auxiliary class Immunology/Inflammation,COX,Natural product, name is 4-Hydroxy-3,5-dimethoxybenzaldehyde, and the molecular formula is C9H10O4, COA of Formula: C9H10O4.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Wang, Jiangli published the artcileIn-Depth Identification of Phenolics Fractionated from Eucalyptus Kraft Lignin, Quality Control of 134-96-3, the publication is Advanced Sustainable Systems (2022), 6(5), 2100406, database is CAplus.

Kraft lignin, the principal byproduct of the pulping industry, is an abundant yet highly underutilized aromatic resource. It is useful due to the vast scales involved as a source of fuels, chems., and functional materials when suitable postprocessing is applied. It is deemed to be a renewable alternative to fossil sources. Because of the extreme complexity of kraft lignin, in-depth composition anal. and chem. structural identification are crucial for the development of effective valorization strategies. This work embarks on the characterization and identification of lignin-derived phenolic compounds in representative hardwood (Eucalyptus) kraft lignin after selective fractionation using a single solvent. Advanced 2D heteronuclear single quantum coherence (HSQC) NMR, ³¹P NMR, and mass spectrometry in combination with synthetic authentic compounds are used for the structural identification of the low-mol.-weight fraction of kraft lignin. A total of 20 phenolic compounds, including several novel monomers (catechols), dimers (diarylethanes, diarylethenes, etc.), and trimers with tri-Ph structures are systematically identified in the Eucalyptus kraft lignin. In addition, polysulfide is detected in the low-mol.-weight fraction, indicating that the oxidative polymerization of S^2-/HS^– occurrs during the kraft pulping process. An improved understanding of kraft lignin, especially the low-Mw fraction, is expected to provide essential information for the selective fractionation and valorization of lignin.

Advanced Sustainable Systems published new progress about 134-96-3. 134-96-3 belongs to ethers-buliding-blocks, auxiliary class Immunology/Inflammation,COX,Natural product, name is 4-Hydroxy-3,5-dimethoxybenzaldehyde, and the molecular formula is C9H22OSi, Quality Control of 134-96-3.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Hou, Zhong-Wei published the artcileCatalyst- and Oxidizing Reagent-Free Electrochemical Benzylic C(sp³)-H Oxidation of Phenol Derivatives, COA of Formula: C9H10O4, the publication is Journal of Organic Chemistry (2022), 87(12), 7806-7817, database is CAplus and MEDLINE.

A site-selective electrochem. approach for the benzylic C(sp³)-H oxidation reaction of phenol derivatives along with hydrogen evolution was developed. The protocol proceeded in an easily available undivided cell at room temperature under catalyst- and oxidizing reagent-free conditions. The corresponding aryl aldehydes and ketones were obtained in satisfactory yields, and the gram-scale synthesis is easy to be carried out.

Journal of Organic Chemistry published new progress about 134-96-3. 134-96-3 belongs to ethers-buliding-blocks, auxiliary class Immunology/Inflammation,COX,Natural product, name is 4-Hydroxy-3,5-dimethoxybenzaldehyde, and the molecular formula is C9H10O4, COA of Formula: C9H10O4.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Chen, Jia published the artcileUtilization of Diaphragma juglandis extract as a natural antioxidant for improving the oxidative stability of soybean oil during deep frying, Category: ethers-buliding-blocks, the publication is Food Chemistry: X (2022), 100359, database is CAplus and MEDLINE.

Lipid oxidation significantly shortens the life of frying oils, and this challenge can be addressed by using antioxidants. This work aimed to investigate the effect of Diaphragma juglandis extract (DJE) on the oxidative stability of soybean oil during deep frying. Tert-butylhydroquinone (TBHQ) and tea polyphenol (TP) were applied as pos. controls. A total of 31 polyphenols were determined in DJE, and catechin, quercitrin, taxifolin, quercetin 3-β-d-glucoside, epicatechin, gallic acid, and 3,4-dihydroxybenzoic acid were the main components. The antioxidants effectively delayed the degradation of triglycerides and inhibited the increase in the contents of p-anisidine, oxidized triglyceride monomers, triglyceride dimers, and triglyceride oligomers, with DJE exhibiting better performance. Moreover, DJE showed better inhibitory effect on the formation of (E)-2-alkenals, (E,E)-2,4-alkadienals, 4-oxo-alkanals, primary alcs., and secondary alcs. detected by ¹H NMR than TBHQ and TP. Therefore, DJE has great potential as an excellent antioxidant in large-scale industrial applications.

Food Chemistry: X published new progress about 134-96-3. 134-96-3 belongs to ethers-buliding-blocks, auxiliary class Immunology/Inflammation,COX,Natural product, name is 4-Hydroxy-3,5-dimethoxybenzaldehyde, and the molecular formula is C9H10O4, Category: ethers-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Wu, Bi-Sha published the artcileMolecular mechanisms for pH-mediated amelioration of aluminum-toxicity revealed by conjoint analysis of transcriptome and metabolome in Citrus sinensis roots, Product Details of C9H10O4, the publication is Chemosphere (2022), 134335, database is CAplus and MEDLINE.

Little is known about the effects of pH-aluminum (Al) interactions on gene expression and/or metabolite profiles in plants. Eleven-week-old seedlings of Citrus sinensis were fertilized with nutrient solution at an Al level of 0 or 1 mM and a pH of 3.0 or 4.0 for 18 wk. Increased pH mitigated Al-toxicity-induced accumulation of callose, an Al-sensitive marker. In this study, we identified more differentially expressed genes and differentially abundant metabolites in pH 4.0 + 1 mM Al-treated roots (P4AR) vs pH 4.0 + 0 mM Al-treated roots (P4R) than in pH 3.0 + 1 mM Al-treated roots (P3AR) vs pH 3.0 + 0 mM Al-treated roots (P3R), suggesting that increased pH enhanced root metabolic adaptations to Al-toxicity. Further anal. indicated that increased pH-mediated mitigation of root Al-toxicity might be related to several factors, including: enhanced capacity to maintain the homeostasis of phosphate and energy and the balance between generation and scavenging of reactive oxygen species and aldehydes; and elevated accumulation of secondary metabolites such as polyphenol, proanthocyanidins and phenolamides and adaptations of cell wall and plasma membrane to Al-toxicity.

Chemosphere published new progress about 134-96-3. 134-96-3 belongs to ethers-buliding-blocks, auxiliary class Immunology/Inflammation,COX,Natural product, name is 4-Hydroxy-3,5-dimethoxybenzaldehyde, and the molecular formula is C2H2N3NaS, Product Details of C9H10O4.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Ran, Jiansu published the artcileSignificant Promotion of Carboxyl Groups in Palladium Nanoparticles-Supported Biomass Carbon Catalysts for Efficient Low-Temperature Hydrodeoxygenation of Lignin Derivatives in Water, Related Products of ethers-buliding-blocks, the publication is ACS Sustainable Chemistry & Engineering (2022), 10(22), 7277-7287, database is CAplus.

Selective and efficient low-temperature hydrodeoxygenation (HDO) of lignin derivatives in water for the production of valuable biofuel and chems. is still challenging. Herein, we reported biomass carbon-supported ultrafine Pd nanoparticles as highly active and stable catalysts for low-temperature HDO of vanillin (a typical lignin-derived compound) to 2-methoxy-4-methylphenol (MMP). We found that the abundant carboxyl groups on the resultant catalyst greatly accelerated the conversion of the generated intermediate (vanillyl alc., VAL), and then, the synergistic catalysis between carboxyl groups and Pd nanoparticles promoted the efficient production MMP through a free-radical pathway. Other lignin derivatives with different functional groups were also efficiently converted to the corresponding products over the prepared catalyst. This work may provide a new idea for designing a biomass-derived catalyst for efficient transformation of various lignin derivatives to produce value-added biofuels and chems.

ACS Sustainable Chemistry & Engineering published new progress about 134-96-3. 134-96-3 belongs to ethers-buliding-blocks, auxiliary class Immunology/Inflammation,COX,Natural product, name is 4-Hydroxy-3,5-dimethoxybenzaldehyde, and the molecular formula is C9H10O4, Related Products of ethers-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem