Category: 122775-35-3

Ethers are a class of organic compounds that contain an ether group—an oxygen atom connected to two alkyl or aryl groups. 122775-35-3, formula is C8H11BO4, Name is 3,4-Dimethoxyphenylboronic acid.They have the general formula R–O–R′, where R and R′ represent the alkyl or aryl groups. Formula: C8H11BO4.

Du, Bingnan;Chan, Chun-Ming;Lee, Pui-Yiu;Cheung, Leong-Hung;Xu, Xin;Lin, Zhenyang;Yu, Wing-Yiu research published 《 2,2-difluorovinyl benzoates for diverse synthesis of gem-difluoroenol ethers by Ni-catalyzed cross-coupling reactions》, the research content is summarized as follows. Structurally diverse 2,2-difluorovinyl benzoates (BzO-DFs) RC(O)₂C(R¹)=C(F₂) (R = C₆H₅, 4-ClC₆H₄, 1-adamantyl, etc.; R¹ = OC₂H₅, OCH₂C₆H₅, 2-CH₃C₆H₄, etc.) and RC(O)₂C(R²)=C(F₂) (R² = 4-(C(CH₃)₃)C₆H₄, 2-CH₃C₆H₄, 4-CH₃OCC₆H₄) developed as versatile building blocks for modular synthesis of gem-difluoroenol ethers RC(R¹)=C(F₂) and R³C(R¹)=C(F)₂ (R³ = C₆H₅, 4-ClC₆H₄, 2-naphthyl, etc.) (44 examples) and gem-difluoroalkenes RC(R¹)=C(F₂) (R¹ = 4-CH₃OC₆H₄, C(CH₃)₃) (2 examples) by Ni-catalyzed cross coupling reactions have been described. Diverse BzO-DFs derivatives bearing sensitive functional groups (e.g., C = C, TMS, strained carbocycles) are readily prepared from their bromodifluoroacetates R¹C(O)C(Br)F₂ and bromodifluoroketones precursors using metallic zinc as reductant. With Ni(COD)₂ and dppf [1,1′-bis(diphenylphosphino)ferrocene] as catalyst, reactions of BzO-DFs with arylboronic acids R³B(OH)₂ and arylmagnesium reagents R²MgBr afforded the desired gem-difluoroenol ethers and gem-difluoroalkenes in good yields. The Ni-catalyzed coupling reactions features highly regioselective C(vinyl)-O(benzoate) bond activation of the BzO-DFs. Results from control experiments and DFT calculations are consistent with a mechanism involving initial oxidative addition of the BzO-DFs by the Ni(0) complex. By virtue of diversity of the BzO-DFs and excellent functional group tolerance, this method is amenable to late-stage functionalization of multifunctionalized bioactive mols.

122775-35-3, 3,4-Dimethoxyphenylboronic acid is a useful research compound. Its molecular formula is C8H11BO4 and its molecular weight is 181.98 g/mol. The purity is usually 95%.
3,4-Dimethoxyphenylboronic acid contains varying amounts of anhydride.
3,4-Dimethoxyphenylboronic acid is a bacterial mutagen. A useful intermediate for organic synthesis.
3,4-Dimethoxyphenylboronic acid is a boronate ester that has been shown to be an effective coupling partner for the Suzuki reaction. It has also been used in cancer therapy and as a photochemical probe for the study of biological properties. 3,4-Dimethoxyphenylboronic acid has been shown to demethylate DNA and inhibit methionine aminopeptidase activity. It also cross-couples with halides, such as chlorides or iodides, and activates tertiary alcohols. 3,4-Dimethoxyphenylboronic acid is soluble in organic solvents and can be used in supramolecular chemistry., Formula: C8H11BO4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers lack the hydroxyl groups of alcohols. Without the strongly polarized O―H bond, ether molecules cannot engage in hydrogen bonding with each other. 122775-35-3, formula is C8H11BO4, Name is 3,4-Dimethoxyphenylboronic acid. Ethers do have nonbonding electron pairs on their oxygen atoms, however, and they can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. HPLC of Formula: 122775-35-3.

Du, Xiaoyong;Xiao, Ye;Yang, Yuhong;Duan, Ya-Nan;Li, Fangfang;Hu, Qi;Chung, Lung Wa;Chen, Gen-Qiang;Zhang, Xumu research published 《 Enantioselective Hydrogenation of Tetrasubstituted α,β-Unsaturated Carboxylic Acids Enabled by Cobalt(II) Catalysis: Scope and Mechanistic Insights》, the research content is summarized as follows. Chiral carboxylic acids are important compounds because of their prevalence in pharmaceuticals, natural products and agrochems. Asym. hydrogenation of α,β-unsaturated carboxylic acids has been widely recognized as one of the most efficient synthetic approaches to afford such compounds Although related asym. hydrogenation of di- and trisubstituted unsaturated acids with noble metals is well established, asym. hydrogenation of challenging tetrasubstituted α,β-unsaturated carboxylic acids is rarely reported. We demonstrate enantioselective hydrogenation of cyclic (2-aryl-1-cycloalkene-1-carboxylic acids) and acyclic (α-isopropylidenearylacetic acids) tetrasubstituted α,β-unsaturated carboxylic acids via cobalt(II) catalysis. This protocol showed broad substrate scope and gave chiral carboxylic acids in good yields with excellent enantiocontrol (up to 98% yield and 99% ee). Combined exptl. and computational mechanistic studies support a Co^II catalytic cycle involving migratory insertion and σ-bond metathesis processes. DFT calculations reveal that enantioselectivity may originate from the steric effect between the Ph groups of the ligand and the substrate.

HPLC of Formula: 122775-35-3, 3,4-Dimethoxyphenylboronic acid is a useful research compound. Its molecular formula is C8H11BO4 and its molecular weight is 181.98 g/mol. The purity is usually 95%.
3,4-Dimethoxyphenylboronic acid contains varying amounts of anhydride.
3,4-Dimethoxyphenylboronic acid is a bacterial mutagen. A useful intermediate for organic synthesis.
3,4-Dimethoxyphenylboronic acid is a boronate ester that has been shown to be an effective coupling partner for the Suzuki reaction. It has also been used in cancer therapy and as a photochemical probe for the study of biological properties. 3,4-Dimethoxyphenylboronic acid has been shown to demethylate DNA and inhibit methionine aminopeptidase activity. It also cross-couples with halides, such as chlorides or iodides, and activates tertiary alcohols. 3,4-Dimethoxyphenylboronic acid is soluble in organic solvents and can be used in supramolecular chemistry., 122775-35-3.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. 122775-35-3, formula is C8H11BO4, Name is 3,4-Dimethoxyphenylboronic acid. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3. Quality Control of 122775-35-3.

Egharevba, Godshelp O.;Kamal, Ahmed;Dosumu, Omotayo O.;Routhu, Sunitha;Fadare, Olatomide A.;Oguntoye, Stephen O.;Njinga, Stanislaus N.;Oluyori, Abimbola P. research published 《 Synthesis and characterization of novel combretastatin analogues of 1,1-diaryl vinyl sulfones, with antiproliferative potential via in-silico and in-vitro studies》, the research content is summarized as follows. Novel 1,1-diaryl vinyl-sulfones I [R = Ph, 4-MeOC₆H₄, 2,4-di-FC₆H₃, etc.] analogs of combretastatin CA-4 were synthesized via Suzuki-Miyaura coupling method and screened for in-vitro antiproliferative activity against four human cancer cell lines: MDA-MB 231(breast cancer), HeLa (cervical cancer), A549 (lung cancer), and IMR-32 (neuroblast cancer), along with a normal cell line HEK-293 (human embryonic kidney cell) by employing 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide (MTT) assay. The compounds synthesized had better cytotoxicity against the A549 and IMR-32 cell lines compared to HeLa and MDA-MB-231 cell lines. The synthesized compounds also showed significant activity on MDA-MB-231 cancer cell line with IC₅₀ of 9.85-23.94μM, and on HeLa cancer cell line with IC₅₀ of 8.39-11.70μM relative to doxorubicin having IC₅₀ values 0.89 and 1.68μM resp. for MDA-MB-231 and HeLa cell lines. All the synthesized compounds were not toxic to the growth of normal cells, HEK-293. They appeared to have a higher binding affinity for the target protein, tubulin, PDB ID = 5LYJ (beta chain), relative to the reference compounds, CA4 (- 7.1 kcal/mol) and doxorubicin (- 7.2 kcal/mol) except for I [R = 3,5-di-MeOC₆H₃, 4-ClC₆H₄, 3,4-di-ClC₆H₃, 4-NCC₆H₄]. The high binding affinity for beta-tubulin was not translated into enhanced cytotoxicity but the compounds I [R = 4-FC₆H₄, 2,4-di-FC₆H₃, 3,4-di-FC₆H₃, 4-ClC₆H₄, 3,4-di-ClC₆H₃, 2-F-5-Me-C₆H₃] that had a higher cell permeability (as predicted in-silico) demonstrated an optimum cytotoxicity against the tested cell lines in an almost uniform manner for all tested cell lines. The in-silico study provided insight into the role that cell permeability plays in enhancing the cytotoxicity of this class of compounds and as potential antiproliferative agents.

Quality Control of 122775-35-3, 3,4-Dimethoxyphenylboronic acid is a useful research compound. Its molecular formula is C8H11BO4 and its molecular weight is 181.98 g/mol. The purity is usually 95%.
3,4-Dimethoxyphenylboronic acid contains varying amounts of anhydride.
3,4-Dimethoxyphenylboronic acid is a bacterial mutagen. A useful intermediate for organic synthesis.
3,4-Dimethoxyphenylboronic acid is a boronate ester that has been shown to be an effective coupling partner for the Suzuki reaction. It has also been used in cancer therapy and as a photochemical probe for the study of biological properties. 3,4-Dimethoxyphenylboronic acid has been shown to demethylate DNA and inhibit methionine aminopeptidase activity. It also cross-couples with halides, such as chlorides or iodides, and activates tertiary alcohols. 3,4-Dimethoxyphenylboronic acid is soluble in organic solvents and can be used in supramolecular chemistry., 122775-35-3.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers lack the hydroxyl groups of alcohols. Without the strongly polarized O―H bond, ether molecules cannot engage in hydrogen bonding with each other. 122775-35-3, formula is C8H11BO4, Name is 3,4-Dimethoxyphenylboronic acid. Ethers do have nonbonding electron pairs on their oxygen atoms, however, and they can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. Recommanded Product: 3,4-Dimethoxyphenylboronic acid.

Fan, Chi-Hang;Xu, Tianyue;Ke, Zhihai;Yeung, Ying-Yeung research published 《 Autocatalytic aerobic ipso-hydroxylation of arylboronic acid with Hantzsch ester and Hantzsch pyridine》, the research content is summarized as follows. Hantzsch esters were very useful hydrogen and electron donors that was applied in many reactions. After the reactions, aromatic Hantzsch pyridines are generated as the byproducts and their roles were commonly ignored. Herein, the use of Hantzsch pyridine as a promoter to activate Hantzsch ester in the generation of the hydrogen peroxy radical, which is useful for the ipso-hydroxylation of arylboronic acids to give phenols was reported. The reaction does not require an external catalyst or light. The conditions were mild and highly compatible with different functional groups.

Recommanded Product: 3,4-Dimethoxyphenylboronic acid, 3,4-Dimethoxyphenylboronic acid is a useful research compound. Its molecular formula is C8H11BO4 and its molecular weight is 181.98 g/mol. The purity is usually 95%.
3,4-Dimethoxyphenylboronic acid contains varying amounts of anhydride.
3,4-Dimethoxyphenylboronic acid is a bacterial mutagen. A useful intermediate for organic synthesis.
3,4-Dimethoxyphenylboronic acid is a boronate ester that has been shown to be an effective coupling partner for the Suzuki reaction. It has also been used in cancer therapy and as a photochemical probe for the study of biological properties. 3,4-Dimethoxyphenylboronic acid has been shown to demethylate DNA and inhibit methionine aminopeptidase activity. It also cross-couples with halides, such as chlorides or iodides, and activates tertiary alcohols. 3,4-Dimethoxyphenylboronic acid is soluble in organic solvents and can be used in supramolecular chemistry., 122775-35-3.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers can again be classified into two varieties: if the alkyl or aryl groups are the same on both sides of the oxygen atom, 122775-35-3, formula is C8H11BO4, Name is 3,4-Dimethoxyphenylboronic acid. Then it is a simple or symmetrical ether, whereas if they are different, the ethers are called mixed or unsymmetrical ethers. Product Details of C8H11BO4.

Darwish, Khaled M.;Abdelwaly, Ahmad;Atta, Asmaa M.;Helal, Mohamed A. research published 《 Discovery of tetrahydro-β-carboline- and indole-based derivatives as promising phosphodiesterase-4 inhibitors: Synthesis, biological evaluation, and molecular modeling studies》, the research content is summarized as follows. Phosphodiesterase-4 (PDE4) is responsible for the selective degradation of the 3′-cyclic phosphate bonds of cAMP. A collection of twenty-three diverse 1,2,3,4-tertahydro-β-carboline- and indole-based analogs were synthesized and assessed for their inhibitory activity against human PDE4. The compounds were prepared using straightforward procedures and characterized using ¹H- and ¹³C NMR, IR, and mass spectroscopy as well as elemental anal. Fifteen of the prepared compounds exhibited significant inhibitory activity with IC₅₀ values in the lower micromolar to upper nanomolar ranges. The most active compounds also showed good selectivity for PDE4 over the related enzyme family member, PDE5, with either insignificant or null% inhibition of the latter enzyme. The indole-based compounds, 21b (I) and 21c (II), showed the most pronounced PDE4 inhibition with IC₅₀ values of 754 and 664 nM, resp. The PDE4B active site comprises both hydrophobic and solvent-filled pockets. The hydrophobic pocket (Q) includes the invariant purine-selective Gln443 which is critical for cAMP. Below this Gln443 lies Phe446 which acts as a hydrophobic P-clamp stabilizing the ligand aromatic ring system. Mol. docking investigation showed preferential anchoring of the active compounds within the PDE4 active site through interactions between the indole nitrogens and the dimethoxy Ph groups with key residues. Overall, the prepared compounds are novel and simple mols. with good potential for future optimization. Showing satisfactory predicted ADME/safety and drug-likeness properties, compound 21c is considered a promising lead for further optimization towards clin. investigation against inflammatory, auto-immune diseases, or certain types of cancer.

Product Details of C8H11BO4, 3,4-Dimethoxyphenylboronic acid is a useful research compound. Its molecular formula is C8H11BO4 and its molecular weight is 181.98 g/mol. The purity is usually 95%.
3,4-Dimethoxyphenylboronic acid contains varying amounts of anhydride.
3,4-Dimethoxyphenylboronic acid is a bacterial mutagen. A useful intermediate for organic synthesis.
3,4-Dimethoxyphenylboronic acid is a boronate ester that has been shown to be an effective coupling partner for the Suzuki reaction. It has also been used in cancer therapy and as a photochemical probe for the study of biological properties. 3,4-Dimethoxyphenylboronic acid has been shown to demethylate DNA and inhibit methionine aminopeptidase activity. It also cross-couples with halides, such as chlorides or iodides, and activates tertiary alcohols. 3,4-Dimethoxyphenylboronic acid is soluble in organic solvents and can be used in supramolecular chemistry., 122775-35-3.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers are a class of organic compounds that contain an ether group—an oxygen atom connected to two alkyl or aryl groups. 122775-35-3, formula is C8H11BO4, Name is 3,4-Dimethoxyphenylboronic acid.They have the general formula R–O–R′, where R and R′ represent the alkyl or aryl groups. Reference of 122775-35-3.

Das, Pritha;Das, Subhodeep;Jana, Ranjan research published 《 Aryldiazonium Salts and DABSO: A Versatile Combination for Three-Component Sulfonylative Cross-Coupling Reactions》, the research content is summarized as follows. A copper-catalyzed three-component cross-coupling of aryldiazonium salts, DABSO with arylboronic acids to obtain medicinally relevant unsym. diarylsulfones RSO₂R¹ [R = Ph, 4-FC₆H₄, 2-naphthyl, etc.; R¹ = 3-ClC₆H₄, 4-MeOC₆H₄, 2-SMeC₆H₄, etc.] was disclosed. Interestingly, a catalyst-free approach for the synthesis of arylvinylsulfones R²CH=CHSO₂R³ [R² = Ph, 4-MeC₆H₄, 4-MeOC₆H₄, etc.; R³ = 4-MeC₆H₄, 3-ClC₆H₄, 4-MeOC₆H₄, 4-IC₆H_4, 3-CO₂MeC₆H₄] from the corresponding vinyl boronic acids or vinyl halides was explored under basic condition. Tethered aryldiazonium salts provided the corresponding annulated dihydrobenzofuran tethered alkylvinyl sulfones I [R⁴ = H, 5-Me, 5-Cl, 5-MeO; R⁵ = Ph, 4-MeC₆H₄, 4-FC₆H₄, 4-ClC₆H₄, 4-F₃CC₆H₄] via alkene difunctionalization under the same transition metal-free condition. Mechanistically, these multicomponent reactions proceeded through a single electron pathway by the formation of arylsulfonyl radical as a key intermediate.

Reference of 122775-35-3, 3,4-Dimethoxyphenylboronic acid is a useful research compound. Its molecular formula is C8H11BO4 and its molecular weight is 181.98 g/mol. The purity is usually 95%.
3,4-Dimethoxyphenylboronic acid contains varying amounts of anhydride.
3,4-Dimethoxyphenylboronic acid is a bacterial mutagen. A useful intermediate for organic synthesis.
3,4-Dimethoxyphenylboronic acid is a boronate ester that has been shown to be an effective coupling partner for the Suzuki reaction. It has also been used in cancer therapy and as a photochemical probe for the study of biological properties. 3,4-Dimethoxyphenylboronic acid has been shown to demethylate DNA and inhibit methionine aminopeptidase activity. It also cross-couples with halides, such as chlorides or iodides, and activates tertiary alcohols. 3,4-Dimethoxyphenylboronic acid is soluble in organic solvents and can be used in supramolecular chemistry., 122775-35-3.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers lack the hydroxyl groups of alcohols. Without the strongly polarized O―H bond, ether molecules cannot engage in hydrogen bonding with each other. 122775-35-3, formula is C8H11BO4, Name is 3,4-Dimethoxyphenylboronic acid. Ethers do have nonbonding electron pairs on their oxygen atoms, however, and they can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. Electric Literature of 122775-35-3.

Dong, Zhenhua;Pan, Hongguo;Gao, Pengwei;Xiao, Yongmei;Fan, Lulu;Chen, Jing;Wang, Wentao research published 《 Palladium Immobilized on a Polyimide Covalent Organic Framework: An Efficient and Recyclable Heterogeneous Catalyst for the Suzuki-Miyaura Coupling Reaction and Nitroarene Reduction in Water》, the research content is summarized as follows. An efficient and recyclable Pd nano-catalyst was developed via immobilization of Pd nanoparticles on polyimide linked covalent organic frameworks (PCOFs) that was facilely prepared through condensation of melamine and 3,3′,4,4′-biphenyltetracarboxylic dianhydride. The Pd nanoparticles (Pd NPs) catalyst was thoroughly characterized by FT-IR, XRD, SEM, TEM. Furthermore, the catalytic activity of Pd NPs catalyst was evaluated by Suzuki-Miyaura coupling reaction and nitroarene reduction in water, resp. The excellent yields of corresponding products revealing revealed that the Pd NPs catalyst could be applied as an efficient and reusable heterogeneous catalyst for above two reactions.

122775-35-3, 3,4-Dimethoxyphenylboronic acid is a useful research compound. Its molecular formula is C8H11BO4 and its molecular weight is 181.98 g/mol. The purity is usually 95%.
3,4-Dimethoxyphenylboronic acid contains varying amounts of anhydride.
3,4-Dimethoxyphenylboronic acid is a bacterial mutagen. A useful intermediate for organic synthesis.
3,4-Dimethoxyphenylboronic acid is a boronate ester that has been shown to be an effective coupling partner for the Suzuki reaction. It has also been used in cancer therapy and as a photochemical probe for the study of biological properties. 3,4-Dimethoxyphenylboronic acid has been shown to demethylate DNA and inhibit methionine aminopeptidase activity. It also cross-couples with halides, such as chlorides or iodides, and activates tertiary alcohols. 3,4-Dimethoxyphenylboronic acid is soluble in organic solvents and can be used in supramolecular chemistry., Electric Literature of 122775-35-3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers are a class of organic compounds that contain an ether group—an oxygen atom connected to two alkyl or aryl groups. 122775-35-3, formula is C8H11BO4, Name is 3,4-Dimethoxyphenylboronic acid.They have the general formula R–O–R′, where R and R′ represent the alkyl or aryl groups. Formula: C8H11BO4.

Du, Bingnan;Chan, Chun-Ming;Lee, Pui-Yiu;Cheung, Leong-Hung;Xu, Xin;Lin, Zhenyang;Yu, Wing-Yiu research published 《 2,2-difluorovinyl benzoates for diverse synthesis of gem-difluoroenol ethers by Ni-catalyzed cross-coupling reactions》, the research content is summarized as follows. Structurally diverse 2,2-difluorovinyl benzoates (BzO-DFs) RC(O)₂C(R¹)=C(F₂) (R = C₆H₅, 4-ClC₆H₄, 1-adamantyl, etc.; R¹ = OC₂H₅, OCH₂C₆H₅, 2-CH₃C₆H₄, etc.) and RC(O)₂C(R²)=C(F₂) (R² = 4-(C(CH₃)₃)C₆H₄, 2-CH₃C₆H₄, 4-CH₃OCC₆H₄) developed as versatile building blocks for modular synthesis of gem-difluoroenol ethers RC(R¹)=C(F₂) and R³C(R¹)=C(F)₂ (R³ = C₆H₅, 4-ClC₆H₄, 2-naphthyl, etc.) (44 examples) and gem-difluoroalkenes RC(R¹)=C(F₂) (R¹ = 4-CH₃OC₆H₄, C(CH₃)₃) (2 examples) by Ni-catalyzed cross coupling reactions have been described. Diverse BzO-DFs derivatives bearing sensitive functional groups (e.g., C = C, TMS, strained carbocycles) are readily prepared from their bromodifluoroacetates R¹C(O)C(Br)F₂ and bromodifluoroketones precursors using metallic zinc as reductant. With Ni(COD)₂ and dppf [1,1′-bis(diphenylphosphino)ferrocene] as catalyst, reactions of BzO-DFs with arylboronic acids R³B(OH)₂ and arylmagnesium reagents R²MgBr afforded the desired gem-difluoroenol ethers and gem-difluoroalkenes in good yields. The Ni-catalyzed coupling reactions features highly regioselective C(vinyl)-O(benzoate) bond activation of the BzO-DFs. Results from control experiments and DFT calculations are consistent with a mechanism involving initial oxidative addition of the BzO-DFs by the Ni(0) complex. By virtue of diversity of the BzO-DFs and excellent functional group tolerance, this method is amenable to late-stage functionalization of multifunctionalized bioactive mols.

122775-35-3, 3,4-Dimethoxyphenylboronic acid is a useful research compound. Its molecular formula is C8H11BO4 and its molecular weight is 181.98 g/mol. The purity is usually 95%.
3,4-Dimethoxyphenylboronic acid contains varying amounts of anhydride.
3,4-Dimethoxyphenylboronic acid is a bacterial mutagen. A useful intermediate for organic synthesis.
3,4-Dimethoxyphenylboronic acid is a boronate ester that has been shown to be an effective coupling partner for the Suzuki reaction. It has also been used in cancer therapy and as a photochemical probe for the study of biological properties. 3,4-Dimethoxyphenylboronic acid has been shown to demethylate DNA and inhibit methionine aminopeptidase activity. It also cross-couples with halides, such as chlorides or iodides, and activates tertiary alcohols. 3,4-Dimethoxyphenylboronic acid is soluble in organic solvents and can be used in supramolecular chemistry., Formula: C8H11BO4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers lack the hydroxyl groups of alcohols. Without the strongly polarized O―H bond, ether molecules cannot engage in hydrogen bonding with each other. 122775-35-3, formula is C8H11BO4, Name is 3,4-Dimethoxyphenylboronic acid. Ethers do have nonbonding electron pairs on their oxygen atoms, however, and they can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. HPLC of Formula: 122775-35-3.

Du, Xiaoyong;Xiao, Ye;Yang, Yuhong;Duan, Ya-Nan;Li, Fangfang;Hu, Qi;Chung, Lung Wa;Chen, Gen-Qiang;Zhang, Xumu research published 《 Enantioselective Hydrogenation of Tetrasubstituted α,β-Unsaturated Carboxylic Acids Enabled by Cobalt(II) Catalysis: Scope and Mechanistic Insights》, the research content is summarized as follows. Chiral carboxylic acids are important compounds because of their prevalence in pharmaceuticals, natural products and agrochems. Asym. hydrogenation of α,β-unsaturated carboxylic acids has been widely recognized as one of the most efficient synthetic approaches to afford such compounds Although related asym. hydrogenation of di- and trisubstituted unsaturated acids with noble metals is well established, asym. hydrogenation of challenging tetrasubstituted α,β-unsaturated carboxylic acids is rarely reported. We demonstrate enantioselective hydrogenation of cyclic (2-aryl-1-cycloalkene-1-carboxylic acids) and acyclic (α-isopropylidenearylacetic acids) tetrasubstituted α,β-unsaturated carboxylic acids via cobalt(II) catalysis. This protocol showed broad substrate scope and gave chiral carboxylic acids in good yields with excellent enantiocontrol (up to 98% yield and 99% ee). Combined exptl. and computational mechanistic studies support a Co^II catalytic cycle involving migratory insertion and σ-bond metathesis processes. DFT calculations reveal that enantioselectivity may originate from the steric effect between the Ph groups of the ligand and the substrate.

HPLC of Formula: 122775-35-3, 3,4-Dimethoxyphenylboronic acid is a useful research compound. Its molecular formula is C8H11BO4 and its molecular weight is 181.98 g/mol. The purity is usually 95%.
3,4-Dimethoxyphenylboronic acid contains varying amounts of anhydride.
3,4-Dimethoxyphenylboronic acid is a bacterial mutagen. A useful intermediate for organic synthesis.
3,4-Dimethoxyphenylboronic acid is a boronate ester that has been shown to be an effective coupling partner for the Suzuki reaction. It has also been used in cancer therapy and as a photochemical probe for the study of biological properties. 3,4-Dimethoxyphenylboronic acid has been shown to demethylate DNA and inhibit methionine aminopeptidase activity. It also cross-couples with halides, such as chlorides or iodides, and activates tertiary alcohols. 3,4-Dimethoxyphenylboronic acid is soluble in organic solvents and can be used in supramolecular chemistry., 122775-35-3.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers can again be classified into two varieties: if the alkyl or aryl groups are the same on both sides of the oxygen atom, 122775-35-3, formula is C8H11BO4, Name is 3,4-Dimethoxyphenylboronic acid. Then it is a simple or symmetrical ether, whereas if they are different, the ethers are called mixed or unsymmetrical ethers. Quality Control of 122775-35-3.

Cho, Hyun-A.;Lee, Yong-Ki;Kim, Seung-Hoi research published 《 Bare Magnetite-Promoted Oxidative Hydroxylation of Arylboronic Acids and Subsequent Conversion into Phenolic Compounds》, the research content is summarized as follows. The simple combination of readily available, recoverable, and recyclable magnetite (Fe₃O₄) nanoparticles and an environmentally friendly oxidant (H₂O₂) induced oxidative hydroxylation of arylboronic acids into their corresponding phenols ArOH [Ar = Ph, 2-MeC₆H₄, 4-MeC₆H₄, etc.] under mild conditions. Moreover, subsequent arylation or alkylation of intermediate with appropriate electrophiles was accomplished in a one-pot system, leading to the formation of halophenols and phenolic derivs ArOR [Ar = Ph, 3-MeC₆H₄, 4-MeC₆H₄, etc.; R = Bn, CH₂(4-FC₆H₄), allyl, etc].

Quality Control of 122775-35-3, 3,4-Dimethoxyphenylboronic acid is a useful research compound. Its molecular formula is C8H11BO4 and its molecular weight is 181.98 g/mol. The purity is usually 95%.
3,4-Dimethoxyphenylboronic acid contains varying amounts of anhydride.
3,4-Dimethoxyphenylboronic acid is a bacterial mutagen. A useful intermediate for organic synthesis.
3,4-Dimethoxyphenylboronic acid is a boronate ester that has been shown to be an effective coupling partner for the Suzuki reaction. It has also been used in cancer therapy and as a photochemical probe for the study of biological properties. 3,4-Dimethoxyphenylboronic acid has been shown to demethylate DNA and inhibit methionine aminopeptidase activity. It also cross-couples with halides, such as chlorides or iodides, and activates tertiary alcohols. 3,4-Dimethoxyphenylboronic acid is soluble in organic solvents and can be used in supramolecular chemistry., 122775-35-3.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem