Category: 121-00-6

Liu, Runzeng published the artcileSynthetic phenolic antioxidants: A review of environmental occurrence, fate, human exposure, and toxicity, Computed Properties of 121-00-6, the main research area is review synthetic phenolic antioxidants environmental occurrence human exposure toxicity.

Synthetic phenolic antioxidants (SPAs) are widely used in various industrial and com. products to retard oxidative reactions and lengthen product shelf life. In recent years, numerous studies have been conducted on the environmental occurrence, human exposure, and toxicity of SPAs. Here, we summarize the current understanding of these issues and provide recommendations for future research directions. SPAs have been detected in various environmental matrixes including indoor dust, outdoor air particulates, sea sediment, and river water. Recent studies have also observed the occurrence of SPAs, such as 2,6-di-tert-butyl-4-methylphenol (BHT) and 2,4-di-tert-butyl-phenol (DBP), in humans (fat tissues, serum, urine, breast milk, and fingernails). In addition to these parent compounds, some transformation products have also been detected both in the environment and in humans. Human exposure pathways include food intake, dust ingestion, and use of personal care products. For breastfeeding infants, breast milk may be an important exposure pathway. Toxicity studies suggest some SPAs may cause hepatic toxicity, have endocrine disrupting effects, or even be carcinogenic. The toxicity effects of some transformation products are likely worse than those of the parent compound For example, 2,6-di-tert-butyl-p-benzoquinone (BHT-Q) can cause DNA damage at low concentrations Future studies should investigate the contamination and environmental behaviors of novel high mol. weight SPAs, toxicity effects of coexposure to several SPAs, and toxicity effects on infants. Future studies should also develop novel SPAs with low toxicity and low migration ability, decreasing the potential for environmental pollution.

Environmental Science & Technology published new progress about Adipose tissue. 121-00-6 belongs to class ethers-buliding-blocks, name is 4-Hydroxy-3-tert-butylanisole, and the molecular formula is C11H16O2, Computed Properties of 121-00-6.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Guo, Hongguang published the artcileHigh Potential of Methane Production from Coal by Fungi and Hydrogenotrophic Methanogens from Produced Water, Name: 4-Hydroxy-3-tert-butylanisole, the main research area is methane coal fungus hydrogenotrophic methanogen water bacteria organic.

Studying in situ microorganisms is essential to understand the formation of biogenic coalbed methane (CBM). Only a few studies have studied the fungi community inhabiting in coal seams although fungi degrade refractory compounds and solubilize coal and even work with methanogens to produce methane. Produced H2O was collected from Qinshui Basin and used as the source of microflora to degrade coal. The function of fungi was analyzed by inhibition of bacteria with antibiotics. The inhibition of bacteria in the microcosms significantly increased the methane yield. Fungi were more favorable to cooperate with hydrogenotrophic methanogens when bacteria were inhibited as Methanobacterium were the predominant archaea accounting for 45.98-86.98% of the sequence reads. The relatively unchanged fungal community and high volatile fatty acids (VFAs) yields (48.70-85.72%) in the presence of antibiotics might contribute to H2 production to facilitate hydrogenotrophic methanogenesis. On the contrary, the dominant methanogens in microcosms without antibiotics gradually changed from Methanobacterium (89.85%) to Methanoceta (46.19%) and finally to Methanobacterium (87.72%). The bacterial community and organic intermediates have also changed greatly over time, which can be the reason for the succession of the methanogens. Probably fungi in produced H2O can play an important role in coal biodegradation to produce VFAs and H2 that support hydrogenotrophic methanogenesis, which could be neg. impacted by the existence of bacteria.

Energy & Fuels published new progress about Acetoanaerobium. 121-00-6 belongs to class ethers-buliding-blocks, name is 4-Hydroxy-3-tert-butylanisole, and the molecular formula is C11H16O2, Name: 4-Hydroxy-3-tert-butylanisole.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Saxena, Shaiphali published the artcileComparative GC-MS and FT-IR analysis of Portulaca oleracea L. and Portulaca quadrifida L. leaf extracts, Recommanded Product: 4-Hydroxy-3-tert-butylanisole, the main research area is Portulaca oleracea quadrifida leaf extract bioactive phytochem GCMS FTIR.

Quality assurance (QA) is an essential task in pharmacognostic field to promote the product standardization. The present study is focused upon phytoconstituent anal. of aqua-methanol leaf extracts of Portulaca oleracea L. and Portulaca quadrifida L. via GC-MS (gas chromatog.-mass spectrometry) and FT-IR (Fourier transform-IR) spectroscopy for formulation of quality medicines and other products. The GC-MS unveiled 72 and 86 bioactive compounds (both major and tracer) of several categories like terpenoids, phenols, steroids, flavonoids, fatty acids, nucleoside, vitamins, etc. The FT-IR chromatogram confirmed various functional groups peaks (cm-1) of amines (-NH2), alcs. (-OH), carboxylic acids (-COOH), ketones (C=O), etc. The present study provides a futuristic platform for researchers to pursue pharmaceutical and food safety assessments and a proper weed management plan.

Pharma Innovation published new progress about Bioactive agents. 121-00-6 belongs to class ethers-buliding-blocks, name is 4-Hydroxy-3-tert-butylanisole, and the molecular formula is C11H16O2, Recommanded Product: 4-Hydroxy-3-tert-butylanisole.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Park, Jae-Min published the artcileEarly Life History of Lefua costata (Cypriniformes : Balitoridae) from Korea., SDS of cas: 121-00-6, the main research area is Early life history; Egg development; Juveniles; Larvae; Lefua costata.

The purpose of this study is to observe the early life history of Korean Lefua costata and use the result as basic taxonomic research data for balitorid fish. The fertilized eggs were light green color with completely circle shape and mean size was 1.21±0.06 mm (n=30). Immediately after hatching, the size of the larvae was 2.81±0.11 mm (n=5) in mean length, with egg yolk. On the 3rd day after hatching, the preflexion larvae had a mean length of 4.64±0.09 mm (n=5), and their mouth was opened to start feeding. On the 8th day after hatching, a mean length of the postflexion larvae was 9.43±0.46 mm (n=5), the distal part of the notochord was bent to 45°, and 16 fin rays were developed on the caudal fin. On the 31st day after hatching, a mean length of juveniles was 22.3±0.85 mm (n=5), and the number of fin rays was the same as that of adult fish with (iv8) dorsal fins and (iii8) anal fins.

Development & reproduction published new progress about Early life history; Egg development; Juveniles; Larvae; Lefua costata. 121-00-6 belongs to class ethers-buliding-blocks, name is 4-Hydroxy-3-tert-butylanisole, and the molecular formula is C11H16O2, SDS of cas: 121-00-6.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Gluska, Hadar published the artcilePostpartum Depression in COVID-19 Days: Longitudinal Study of Risk and Protective Factors, Recommanded Product: 4-Hydroxy-3-tert-butylanisole, the main research area is COVID-19; EPDS; birth; post-partum depression.

COVID-19 impacted the childbirth experience and increased the rates of postpartum depression (PPD). We assessed the longitudinal effects of the pandemic on the rates of PPD and evaluated the PPD causes and symptoms among women who delivered during the first COVID-19 quarantine in Israel. The participants completed online questionnaires 3 (T1) and 6 mo (T2) following delivery. We used the ‘COVID-19 exposure’ questionnaire, while PPD symptoms, situational anxiety, and social support were evaluated with the EPDS, STAI, and MSPSS questionnaires. The mean EPDS scores increased between T1 and T2 (6.31 ± 5.6 vs. 6.92 ± 5.9, mean difference -0.64 ± 4.59 (95% CI (-1.21)-(-0.06)); t (244) = -2.17, p = 0.031), and the STAI scores decreased (45.35 ± 16.4 vs. 41.47 ± 14.0, t(234) = 4.39, p = 0.000). Despite the exposure to an increased number of COVID-19 events (3.63 ± 1.8 vs. (6.34 ± 2.3)), the impact of exposure decreased between T1 and T2 (8.91 ± 4.6 vs. 7.47 ± 4.1), p < 0.001). In the MSPSS, significant differences were noted on the family scale between the T1 (6.10 ± 1.3) and T2 (5.91 ± 1.4) scores; t (216) = 2.68, p = 0.0008. A regression anal. showed three statistically significant variables that correlated with increased EPDS scores: the MSPSS family subscale (F (1212.00) = 4.308, p = 0.039), the STAI scores (F (1212.00) = 31.988, p = 0.000), and the impact of exposure to COVID-19 (F (1212.00) = 5.038, p = 0.026). The rates of PPD increased for women who delivered during the first COVID-19 lockdown. Further research is warranted to help reduce PPD among these women. Journal of Clinical Medicine published new progress about COVID-19; EPDS; birth; post-partum depression. 121-00-6 belongs to class ethers-buliding-blocks, name is 4-Hydroxy-3-tert-butylanisole, and the molecular formula is C11H16O2, Recommanded Product: 4-Hydroxy-3-tert-butylanisole.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Lei, Caiyu published the artcileMolecular hybridization of grape seed extract: Synthesis, structural characterization and anti-proliferative activity in vitro, Computed Properties of 121-00-6, the main research area is grape seed antiproliferative structural property; Anti-proliferation; Antioxidant; Grape seed extract; HepG2 cell; Hybridization.

The grape seed extract (GSE) hybridized with medium-chain saturated fatty acids (decanoic acid) exhibited higher lipophilicity, antioxidant activity, and anti-proliferative activity than its parents. The chem. structures of individual hybridized GSE derivatives were identified as 3′-O-decanoyl catechin, 3′-O-decanoyl epicatechin, 3′, 5′-2-O-decanoyl epigallocatechin, and 3′, 4′, 3”, 5”-4-O-decanoyl epicatechin gallate by HPLC-MS2 and 1H and 13C NMR. For growth inhibitory effect on HepG2 cells, hybridized GSE derivatives (EC50 = 44.38μg/mL) were significantly (p < 0.01) stronger than natural GSE (EC50 = 60.83μg/mL) due to increased lipophilicity. The effects of GSE derivatives on apoptosis and cell cycle in HepG2 cells were further evaluated by flow cytometry. The results showed that the percentage of apoptotic cells increased markedly in the presence of hybridized GSE derivatives Moreover, hybridized GSE derivatives were capable of inducing cell cycle arrest in G1 phase. This research suggests that hybridized GSE derivatives are effective lipophilic antioxidants and show the potential as adjuvant therapy for cancer. Food Research International published new progress about Grape. 121-00-6 belongs to class ethers-buliding-blocks, name is 4-Hydroxy-3-tert-butylanisole, and the molecular formula is C11H16O2, Computed Properties of 121-00-6.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Jia, Wei published the artcileFoodomics analysis of natural aging and gamma irradiation maturation in Chinese distilled Baijiu by UPLC-Orbitrap-MS/MS, Related Products of ethers-buliding-blocks, the main research area is Baijiu gamma irradiation flavor; Aging; Baijiu; Foodomics; Gamma irradiation.

Classification of Feng-flavor Baijiu considering aging category was furnished with a comprehensive fingerprinting strategy which used UPLC-Orbitrap and foodomics, and the most discriminant 29 compounds related to aging, 15 organic acids, 8 esters as well as some carbonyl compounds were discovered. Increase of aromatic organic acids, decline of carcinogenic di-Bu phthalate and generation of numerous aromatic substances in Baijiu were caused by irradiation until the system reached a relatively stable state which needed 28 days. It is similarity of phys. and chem. reaction process of natural aging and irradiation maturation that both can facilitate flavor of base Baijiu, while the aging time can be plainly shorten utilizing irradiation for Baijiu, whose outcome has been demonstrated by LC-MS and sensory evaluation. The combination of UPLC-Orbitrap and foodomics was applied as a valid tactic to analyze a complex system and gamma irradiation can be a powerful tool to promote Baijiu aging.

Food Chemistry published new progress about Baijiu. 121-00-6 belongs to class ethers-buliding-blocks, name is 4-Hydroxy-3-tert-butylanisole, and the molecular formula is C11H16O2, Related Products of ethers-buliding-blocks.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ye, Zhihong published the artcileElectrochemical treatment of butylated hydroxyanisole: Electrocoagulation versus advanced oxidation, Category: ethers-buliding-blocks, the main research area is butylated hydroxyanisole electrocoagulation advanced oxidation electrochem treatment.

This work compares the removal of butylated hydroxyanisole (BHA), a ubiquitous antioxidant in food and pharmaceuticals, from water either by electrocoagulation (EC) with an Fe|Fe cell or H2O2-based electrochem. advanced oxidation processes like electrochem. oxidation (EO-H2O2), electro-Fenton (EF) and photoelectro-Fenton (PEF) with an air-diffusion cathode. BHA degradation by EC was very poor, whereas the dissolved organic carbon (DOC) was more effectively abated in urban wastewater. The effect of pH, number of Fe|Fe pairs and current on the EC performance was examined The additive was also slowly degraded by EO-H2O2 with a RuO2-based or BDD anode in 50mM Na2SO4 solution In the simulated matrix, BHA decay by EO-H2O2 was substantially enhanced owing to active chlorine generation from anodic oxidation of Cl-, whereas the ·OH-mediated oxidation at the BDD surface accounted for DOC decay. In EF and PEF, the ·OH produced in the bulk upgraded the mineralization, primordially using BDD. In raw urban wastewater at natural pH 7.9, the time course of BHA and DOC contents was affected by NOM oxidation, being accelerated in the order: EO-H2O2Category: ethers-buliding-blocks.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Gyori, Eniko published the artcileSupercritical CO2 extraction and selective adsorption of aroma materials of selected spice plants in functionalized silica aerogels, Product Details of C11H16O2, the main research area is supercritical CO2 extraction squalene spathulenol adsorption silica aerogel.

Static supercritical fluid extraction has been used to concentrate the aroma materials of common herbs and spices. The technique has provided a higher number of components and cleaner extract than the one-step ethanol maceration. The one-step supercritical fluid extraction of the aroma compounds has been combined with their in situ adsorption in hydrophilic and hydrophobic silica aerogels. The extracts have been analyzed by a GC-MS technique and 55 aroma compounds have been identified. Most of the compounds have been adsorbed in both polar and apolar silica aerogels with no direct connection with the surface polarity. However, previously undetected compounds enriched to an anal. significant level, while others competed with each other for the active sites on the surface. Functionalized silica aerogels can be used as a new type of aroma storage materials and as selective and tuneable adsorbents for the extraction and enrichment of potentially active components from a complex matrix.

Journal of Supercritical Fluids published new progress about Aerogels. 121-00-6 belongs to class ethers-buliding-blocks, name is 4-Hydroxy-3-tert-butylanisole, and the molecular formula is C11H16O2, Product Details of C11H16O2.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Blanco-Zubiaguirre, L. published the artcileTarget and suspect screening of substances liable to migrate from food contact paper and cardboard materials using liquid chromatography-high resolution tandem mass spectrometry, Computed Properties of 121-00-6, the main research area is food contact paper cardboard substance migration LC HRMS; Food contact paper and board materials; Liquid chromatography-high resolution mass spectrometry; Migration; Quantitative target analysis; Suspect screening; Tenax®.

This work describes the anal. of both target and non-target compounds in paper and cardboard materials together with the characterization of their migration to Tenax by means of liquid chromatog. coupled to both low (LC-QqQ) and high resolution tandem mass spectrometry (LC-q-Orbitrap), resp. To this aim, an entire anal. procedure was fully developed and validated for both matrixes: paper/cardboard and Tenax. A total of 97 chems., including photoinitiators, phthalates, biocides, antioxidants, etc., listed by the European Regulation, were found in the materials under study together with other substances not included in this list. Moreover, the majority of annotated substances were present in the simulant, giving evidence of their migration capacity. Migration percentages of 10 photoinitiators, 4 phthalates, bisphenol A, bis-(2-ethylhexyl) adipate, acetyltributyl citrate and caprolactam to Tenax were quantified. Despite not exceeding the established specific migration limit (SML) in any case, benzophenone, 4-phenylbenzophenone and bisphenol A concentrations in some paper and cardboard materials were very close to the SML values established by the EU legislation.

Talanta published new progress about Diffusion. 121-00-6 belongs to class ethers-buliding-blocks, name is 4-Hydroxy-3-tert-butylanisole, and the molecular formula is C11H16O2, Computed Properties of 121-00-6.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem