Category: 111-90-0

Ethers do have nonbonding electron pairs on their oxygen atoms, 111-90-0, formula is C6H14O3, Name is Diethylene Glycol Monoethyl Ether. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds. Application of C6H14O3.

Daryab, Mahshid;Faizi, Mehrdad;Mahboubi, Arash;Aboofazeli, Reza research published 《 Preparation and characterization of lidocaine-loaded, microemulsion-based topical gels》, the research content is summarized as follows. Microemulsion-based gels (MBGs) were prepared for transdermal delivery of lidocaine and evaluated for their potential for local anesthesia. Lidocaine solubility was measured in various oils, and phase diagrams were constructed to map the concentration range of oil, surfactant, cosurfactant, and water for oil-in-water (o/w) microemulsion (ME) domains, employing the water titration method at different surfactant/cosurfactant weight ratios. Refractive index, elec. conductivity, droplet size, zeta potential, pH, viscosity, and stability of fluid o/w MEs were evaluated. Carbomer 940 was incorporated into the fluid drug-loaded MEs as a gelling agent. Microemulsion-based gels were characterized for spreadability, pH, viscosity, and in-vitro drug release measurements, and based on the results obtained, the best MBGs were selected and subsequently subjected to ex-vivo rat skin permeation anesthetic effect and irritation studies. Data indicated the formation of nano-sized droplets of MEs ranging from 20-52 nm with a polydispersity of less than 0.5. In-vitro release and ex-vivo permeation studies on MBGs showed significantly higher drug release and permeation in comparison to the marketed topical gel. Developed MBG formulations demonstrated greater potential for transdermal delivery of lidocaine and advantage over the com. available gel product, and therefore, they may be considered as potential vehicles for the topical delivery of lidocaine.

111-90-0, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., Application of C6H14O3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. 111-90-0, formula is C6H14O3, Name is Diethylene Glycol Monoethyl Ether. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3. SDS of cas: 111-90-0.

Doke, Vishakha Vishwanath;Gupta, Khemchand;Khutle, Nilesh M.;Desai, Abhishek research published 《 Formulation and evaluation of self-nanoemulsifying drug delivery system of Ezetimibe》, the research content is summarized as follows. The contemporary research was done with the goal of development and characterization of self-emulsifying drug delivery system of Ezetimibe (EZE) which is poorly water soluble and also to enhance its solubility in biol. fluid, in order to improve dissolution as well as permeability which would lead to enhanced oral bioavailability of drug. Liquid SNEDDS (L-SNEDDS) was formulated using Capmul MCM C8 EP, Cremophore RH 40 and Labrafil M 2125 CS as oil, surfactant and co-surfactant resp. Optimized L-SNEDDS formulation was found to be efficient with average %T of 99.5%, drug content of 98.43%, flask inversion 0 numbers, average particle size of 36.7 nm, zeta potential of -57.5 mV, Polydispersibility index in of 0.119. Also, the in vitro release profile of drug from L-SNEDDS encapsulated in hard gelatin capsules was evaluated in different dissolution media viz. simulated gastric fluid and simulated intestinal fluid. For the drug, more than 95% cumulative release was observed within 30 min exclusive of the pH of the medium. The L-SNEDDS were adsorbed on solid support and then mixed with tablet blends and compressed into tablets. Further, no adverse changes in globule size, shape, zeta potential of SNEDDS and dissolution profile were apparent on conversion to solid powder form and tablet form.

111-90-0, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., SDS of cas: 111-90-0

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers can again be classified into two varieties: if the alkyl or aryl groups are the same on both sides of the oxygen atom, 111-90-0, formula is C6H14O3, Name is Diethylene Glycol Monoethyl Ether. Then it is a simple or symmetrical ether, whereas if they are different, the ethers are called mixed or unsymmetrical ethers. Recommanded Product: Diethylene Glycol Monoethyl Ether.

Doty, Anna C.;Wilson, A. Dan;Forse, Lisa B.;Risch, Thomas S. research published 《 Biomarker Metabolites Discriminate between Physiological States of Field, Cave and White-nose Syndrome Diseased Bats》, the research content is summarized as follows. Anal. of volatile organic compound (VOC) emissions using electronic-nose (e-nose) devices has shown promise for early detection of white-nose syndrome (WNS) in bats. Tricolored bats, Perimyotis subflavus, from three sep. sampling groups defined by environmental conditions, levels of phys. activity, and WNS-disease status were captured temporarily for collection of VOC emissions to determine relationships between these combinations of factors and physiol. states, Pseudogymnoascus destructans (Pd)-infection status, and metabolic conditions. Physiol. active (non-torpid) healthy individuals were captured outside of caves in Arkansas and Louisiana. In addition, healthy and WNS-diseased torpid bats were sampled within caves in Arkansas. Whole-body VOC emissions from bats were collected using portable air-collection and sampling-chamber devices in tandem. Electronic aroma-detection data using three-dimensional Principal Component Anal. provided strong evidence that the three groups of bats had significantly different e-nose aroma signatures, indicative of different VOC profiles. This was confirmed by differences in peak numbers, peak areas, and tentative chem. identities indicated by chromatograms from dual-column GC-analyses. The numbers and quantities of VOCs present in whole-body emissions from physiol. active healthy field bats were significantly greater than those of torpid healthy and diseased cave bats. Specific VOCs were identified as chem. biomarkers of healthy and diseased states, environmental conditions (outside and inside of caves), and levels of physiol. activity. These results suggest that GC/E-nose dual-technologies based on VOC-detection and analyses of physiol. states, provide noninvasive alternative means for early assessments of Pd-infection, WNS-disease status, and other physiol. states.

Recommanded Product: Diethylene Glycol Monoethyl Ether, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., 111-90-0.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers can again be classified into two varieties: if the alkyl or aryl groups are the same on both sides of the oxygen atom, 111-90-0, formula is C6H14O3, Name is Diethylene Glycol Monoethyl Ether. Then it is a simple or symmetrical ether, whereas if they are different, the ethers are called mixed or unsymmetrical ethers. Formula: C6H14O3.

Duffield, Sophie;Da Via, Luigi;Bellman, Amelia Celeste;Chiti, Fabio research published 《 Automated High-Throughput Partition Coefficient Determination with Image Analysis for Rapid Reaction Workup Process Development and Modeling》, the research content is summarized as follows. With this work, the authors explore the application of a novel image anal. algorithm in combination with a high-throughput automated workflow to extract partition coefficient measurements and full mass balance from small-scale samples. An image anal. algorithm was developed in MATLAB R2018b to determine the volume of the aqueous and organic phases of the biphasic samples with 95% accuracy. The automated workflow used <1% of the typical reagent amounts and provided up to 94% time savings when compared with the conventional partition coefficient determination studies. This approach also proves that it is possible to build thermodn. models for liquid-liquid equilibrium process steps using small-scale vessels (8 mL) and identify the impact of varying process parameters in silico. The model could predict the system behavior at a kilo scale and resulted in an optimized set of process conditions that increased the product recovery from 88 to 94% theor. The good agreement between the model and the exptl. data also enabled the impact of process parameters on a critical impurity to be determined, supporting risk assessment and quality by design activities for the case study highlighted.

Formula: C6H14O3, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., 111-90-0.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers lack the hydroxyl groups of alcohols. Without the strongly polarized O―H bond, ether molecules cannot engage in hydrogen bonding with each other. 111-90-0, formula is C6H14O3, Name is Diethylene Glycol Monoethyl Ether. Ethers do have nonbonding electron pairs on their oxygen atoms, however, and they can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. Name: Diethylene Glycol Monoethyl Ether.

Echeverry, Sandra M.;Rey, Diana;Valderrama, Ivonne H.;Araujo, Bibiana Verlindo de;Aragon, Diana Marcela research published 《 Development of a self-emulsifying drug delivery system (SEDDS) to improve the hypoglycemic activity of Passiflora ligularis leaves extract》, the research content is summarized as follows. This work aimed to develop, optimize, and evaluate the hypoglycemic activity of P. ligularis leaves extract (PLE) loaded self-emulsifying drug delivery system (SEDDS). The formulation components (oil, surfactant, and co-solvent) were selected based on the solubility studies. A Box-Behnken design (BBD) with 27 treatments was employed to find the optimal composition of PLE-SEDDS, analyzing the droplet size as the response variable. The polydispersity index (PDI) and zeta potential parameters were also measured. The pharmacol. activity was evaluated through a glucose tolerance test. According to ANOVA for the droplet size variable, the linear model was highly significant (p < 0.001), and oil, surfactant, co-solvent, and silicone polymer (PDMSHEPMS) content and their interactions were statistically significant. The final composition of PLE-SEDDS was castor oil, Cremophor EL, propylene glycol, PDMSHEPMS in proportions of 31: 120: 80: 30, resp. The amount of P. ligularis extract incorporated in the formulation was 20%. The final formulation showed a 45.93 ± 1.02 nm droplet size with a PDI 0.27 ± 0.03 and zeta potential -10.92 ± 0.42 mV. Finally, in the in vivo glucose tolerance test, PLE-SEDDS improved hypoglycemic activity compared to the unformulated extract

Name: Diethylene Glycol Monoethyl Ether, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., 111-90-0.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers can again be classified into two varieties: if the alkyl or aryl groups are the same on both sides of the oxygen atom, 111-90-0, formula is C6H14O3, Name is Diethylene Glycol Monoethyl Ether. Then it is a simple or symmetrical ether, whereas if they are different, the ethers are called mixed or unsymmetrical ethers. Application In Synthesis of 111-90-0.

Choi, Hoo-kyun;Acharya, Gayathri;Lee, Yugyung;Lee, Chi H. research published 《 A Data-Mining Approach for the Quantitative Assessment of Physicochemical Properties of Molecular Compounds in the Skin Flux》, the research content is summarized as follows. This paper aimed to provide an insight into the mechanism of transdermal penetration of drug mols. with respect to their physicochem. properties, such as solubility (S), the presence of enantiomer (ET) and logarithm of octanol-water partition coefficient (log P), mol. weight (MW), and m.p. (MP). Propionic acid derivatives were evaluated for their flux through full-thickness skin excised from hairless mice upon being delivered from silicone-based pressure-sensitive adhesive (PSA) matrixes in the presence or absence of various enhancers. The skin fluxes of model compounds were calculated based on the data obtained using the method engaged with the diffusion cell system. The statistical design of experiments (DoE) based on the factorial approach was used to find variables that have a significant impact on the outcomes. For the prediction of skin flux, a quant. equation was derived using the data-mining approach on the relationship between skin permeation of model compounds (∼125 mg/mL) and involved physicochem. variables. The most influential variables for the skin flux of propionic acid derivatives were the m.p. (0.97) followed by the presence of enantiomer (0.95), mol. mass (0.93), log P values (0.86), and aqueous solubility (0.80). It was concluded that the skin flux of mol. compounds can be predicted based on the relationship between their physicochem. properties and the interaction with cofactors including additives and enhancers in the vehicles.

111-90-0, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., Application In Synthesis of 111-90-0

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. 111-90-0, formula is C6H14O3, Name is Diethylene Glycol Monoethyl Ether. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3. Application of C6H14O3.

Dangre, Pankaj V.;Gurram, Navya J.;Surana, Sanjay J.;Chalikwar, Shailesh S. research published 《 Development and Optimization of Vitamin D₃ Solid Self-Microemulsifying Drug Delivery System: Investigation of Flowability and Shelf Life》, the research content is summarized as follows. Abstract: We report herein the design of a solid self-microemulsifying drug delivery system (SMEDDS) of vitamin D3 for augmentation of its solubility and dissolution The studies employed a 32 full factorial design by employing JMP 13.2.1, software for preparation of liquid SMEDDS. Further, the prediction profiler was utilized to optimized liquid SMEDDS-Vit.D3 (OF) formulation. The solidification of liquid SMEDDS-Vit. D3 formulation was carried out by phys. adsorption over Neusilin US2 and Aerosil 200 carriers. Solid-state evaluation of SMEDDS-Vit. D3 suggested the transformation of crystalline to amorphous form of Vit. D3 which is responsible for imparting more aqueous solubility and thus enhancement in dissolution behavior. The investigation of flow behaviors viz. flow function (FF) and effective angle of wall friction (EAWF) of solid SMEDDS-Vit. D3 was performed using powder flow tester. Solid SMEDDS-Vit. D3 prepared using Neusilin US2 showed good flow behavior and hence was developed into tablets. The tablets showed good quality control parameters as per pharmacopeial standards The in vitro dissolution studies demonstrated more dissolution of Vit. D3 in SMEDDS (liquid, solid, and tablet) when compared to the unprocessed drug. The shelf life (T90) of tablets was reported to be 28.12 mo suggesting excellent stability of Vit.D3 in solid SMEDDS. In nutshell, our research works explore the utilization of SMEDDS for the oral delivery of Vit. D3 to gain maximum health-related benefits. Graphical abstract: [graphic not available: see fulltext].

111-90-0, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., Application of C6H14O3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers lack the hydroxyl groups of alcohols. Without the strongly polarized O―H bond, ether molecules cannot engage in hydrogen bonding with each other. 111-90-0, formula is C6H14O3, Name is Diethylene Glycol Monoethyl Ether. Ethers do have nonbonding electron pairs on their oxygen atoms, however, and they can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. Related Products of 111-90-0.

Ansari, Mohd Nazam;Soliman, Gamal A.;Rehman, Najeeb Ur;Anwer, Khalid Md. research published 《 Crisaborole Loaded Nanoemulsion Based Chitosan Gel: Formulation, Physicochemical Characterization and Wound Healing Studies》, the research content is summarized as follows. The development of an effective gel capable of treating eczema remains a challenge in medicine. Because of its greater retention in the affected area, good absorption of wound exudates, and induction of cell growth, nanogel is widely investigated as a topical preparation Chitosan gel based on nanoemulsions has received much attention for its use in wound healing. In this study, four formulas (CRB-NE1-CRB-NE4) of crisaborole-loaded nanoemulsions (CRB-NEs) were developed using lauroglycol 90 as an oil, Tween-80 as a surfactant, and transcutol-HP (THP) as a co-surfactant. The prepared NEs (CRB-NE1-CRB-NE4) were evaluated for their physicochem. properties. Based on vesicle size (64.5 ± 5.3 nm), polydispersity index (PDI) (0.202 ± 0.06), zeta potential (ZP, -36.3 ± 4.16 mV), refractive index (RI, 1.332 ± 0.03), and percent transmittance (% T, 99.8 ± 0.12) was optimized and further incorporated into chitosan (2%, weight/weight) polymeric gels. The CRB-NE1-loaded chitosan gel was then evaluated for its drug content, spreadability, in-vitro release, flux, wound healing, and anti-inflammatory studies. The CRB-NE1-loaded chitosan gel exhibited a flux of 0.211 mg/cm²/h, a drug release of 74.45 ± 5.4% CRB released in 24 h with a Korsmeyer-Peppas mechanism release behavior. The CRB-NE1-loaded gel exhibited promising wound healing and anti-inflammatory activities.

Related Products of 111-90-0, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., 111-90-0.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers can again be classified into two varieties: if the alkyl or aryl groups are the same on both sides of the oxygen atom, 111-90-0, formula is C6H14O3, Name is Diethylene Glycol Monoethyl Ether. Then it is a simple or symmetrical ether, whereas if they are different, the ethers are called mixed or unsymmetrical ethers. Recommanded Product: Diethylene Glycol Monoethyl Ether.

Anwer, Khalid Md;Iqbal, Muzaffar;Aldawsari, Mohammed F.;Alalaiwe, Ahmed;Ahmed, Mohammed Muqtader;Muharram, Magdy M.;Ezzeldin, Essam;Mahmoud, Mohamed A.;Imam, Faisal;Ali, Raisuddin research published 《 Improved antimicrobial activity and oral bioavailability of delafloxacin by self-nanoemulsifying drug delivery system (SNEDDS)》, the research content is summarized as follows. In the current study, a novel self-nanoemulsifying drug delivery system (SNEDDS) was developed in order to improve the oral bioavailability of delafloxacin (DLF). Various oils, surfactants and co-surfactants were screened by solubility studies. Based on solubilization, potential of DLF in various vehicles, Lauroglycol-90 (oil), Tween 80 (surfactant) and Transcutol-HP (co-surfactant) were selected for the development of DLF loaded SNEDDS (DLF-SNEDDS). Four formulas of DLF loaded SNEDDS (DLF1-DLF4) were prepared and evaluated for their droplet size, polydispersity index (PDI), zeta potential (ZP), refractive index (RI), percent transmittance (%T), thermodn. stability, emulsifying efficiency and in vitro release studies. Among developed DLF loaded SNEDDS (DLF1-DLF4), DLFI was found optimum with a droplet size (73.3 ± 6.5 nm) PDI (0.298) ZP (-22.3) RI (1.334 ± 0.05) and %T (99.2 ± 0.09). Optimized DLF loaded SNEDDS (DLF1) demonstrated a superior anti-microbial activity against tested gram pos. and gram neg. strains with no resistance. The pharmacokinetic studies showed that oral bioavailability of DLF was significantly improved (3- fold) by optimized DLF loaded SNEDDS (DLF1) in comparison to pure DLF suspension. Hence, the results of this work suggest that the developed SNEDDS could be a potential carrier in enhancing bioavailability and therapeutic efficacy of DLF.

Recommanded Product: Diethylene Glycol Monoethyl Ether, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., 111-90-0.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers do have nonbonding electron pairs on their oxygen atoms, 111-90-0, formula is C6H14O3, Name is Diethylene Glycol Monoethyl Ether. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds. Formula: C6H14O3.

Araujo, Gustavo Parreira;Martins, Felipe Terra;Taveira, Stephania Fleury;Cunha-Filho, Marcilio;Marreto, Ricardo Neves research published 《 Effects of Formulation and Manufacturing Process on Drug Release from Solid Self-emulsifying Drug Delivery Systems Prepared by High Shear Mixing》, the research content is summarized as follows. This study sought to investigate the influence of formulation and process factors of the high shear mixing (HSM) on the properties of solid self-emulsifying drug delivery systems (S-SEDDS) containing the model drug carvedilol (CAR). Firstly, liquid SEDDS (L-SEDDS) were prepared by mixing castor oil with different proportions of surfactant (Solutol or Kolliphor RH40) and cosolvent (Transcutol or PEG400). A miscible L-SEDDS with high drug solubility (124.3 mg/g) was selected and gave rise to 10% (m/m) CAR loaded-emulsion with reduced particle size. Then, a factorial exptl. design involving five component′s concentration and two process factors was used to study the solidification of the selected L-SEDDS by HSM. CAR content, diffractometric profile, and in vitro dissolution were determined Morphol. and flow analyses were also performed. Porous and spherical particles with mean sizes ranging from 160 to 210 μm were obtained. Particle size was not affected by any formulation factor studied. Powder flowability, in turn, was influenced by L-SEDDS and crospovidone concentration CAR in vitro dissolution from S-SEDDS was significantly increased compared to the drug as supplied and was equal (pH 1.2) or lower (pH 6.8) than that determined for L-SEDDS. Colloidal silicon dioxide decreased drug dissolution, whereas an increase in water-soluble diluent lactose and L-SEDDS concentration increased CAR dissolution The proper selection of liquid and solid constituents proved to be crucial to developing an S-SEDDS by HSM. Indeed, the results obtained here using exptl. design contribute to the production of S-SEDDS using an industrially viable process.

111-90-0, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., Formula: C6H14O3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem