Category: 10305-42-7

Sherman, E. S.; Chemler, S. R. published the artcile< Product class 12: N-Alkylsulfamic acid derivatives>, Safety of n-Propylsulphamoyl chloride, the main research area is review alkylsulfamic acid derivative preparation organic synthesis.

A review of methods to prepare N-alkylsulfamic acid derivatives

Science of Synthesis published new progress about Organic synthesis. 10305-42-7 belongs to class ethers-buliding-blocks, and the molecular formula is C3H8ClNO2S, Safety of n-Propylsulphamoyl chloride.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Holan, George; Virgona, Chris T.; Watson, Keith G.; Finkelstein, Bruce L. published the artcile< Synthesis, insecticidal and anti-acetylcholinesterase activity of a new class of heterocyclic methanesulfonates>, Name: n-Propylsulphamoyl chloride, the main research area is pyrazoline methanesulfonate preparation insecticide acetylcholinesterase inhibitor.

A series of 3-methanesulfonyloxy-2-pyrazolines I (R1 = Me, Ph, CHMe2, R2 = Me, H, X = CONH2, CONHPh, CONHCMe3, SO2NMe2, etc.) were prepared by mesylation of the corresponding pyrazolidin-3-ones. The compounds exhibited strong insecticidal and anti-acetylcholinesterase activity.

Bioorganic & Medicinal Chemistry Letters published new progress about Insecticides. 10305-42-7 belongs to class ethers-buliding-blocks, and the molecular formula is C3H8ClNO2S, Name: n-Propylsulphamoyl chloride.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Cano, Carolina; Pavon, Javier; Serrano, Antonia; Goya, Pilar; Paez, Juan Antonio; Rodriguez de Fonseca, Fernando; Macias-Gonzalez, Manuel published the artcile< Novel Sulfamide Analogs of Oleoylethanolamide Showing In Vivo Satiety Inducing Actions and PPARα Activation>, Electric Literature of 10305-42-7, the main research area is sulfamide oleoylethanolamide analog preparation peroxisome proliferator activated receptor.

Long chain saturated and unsaturated alkyl sulfamide and Pr sulfamide derivatives, analogs of oleoylethanolamide, were synthesized and evaluated in vivo and in vitro as peroxisome proliferator activated receptor alpha (PPARα) activators. Addnl., the anorexic effects of the new compounds were studied in vivo in food-deprived rats. Among the active compounds N-octadecyl-N’-propylsulfamide was identified as a potent hypolipidemic compound, a potent feeding suppressant, and a concentration-dependent activator of PPARα.

Journal of Medicinal Chemistry published new progress about Peroxisome proliferator-activated receptor α Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 10305-42-7 belongs to class ethers-buliding-blocks, and the molecular formula is C3H8ClNO2S, Electric Literature of 10305-42-7.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Prasad, J. V. N. Vara; Markoski, Larry J.; Boyer, Fred E.; Domagala, John M.; Ellsworth, Edmund L.; Gajda, Christopher; Hagen, Susan E.; Tait, Bradley D.; Lunney, Elizabeth A.; Tummino, Peter J.; Ferguson, Donna; Holler, Tod; Hupe, Donald; Nouhan, Carolyn; Gracheck, Stephen J.; VanderRoest, Steven; Saunders, James; Iyer, K.; Sinz, M. published the artcile< Nonpeptidic HIV protease inhibitors: 6-alkyl-5,6-dihydro-2-pyranones possessing a novel and achiral 3-(2-t-butyl-5-methyl-4-sulfamate)phenylthio moiety>, Quality Control of 10305-42-7, the main research area is HIV protease inhibitor sulfamate hydroxyphenylethyloxopyranylthiophenyl ester preparation; virucide sulfamate hydroxyphenylethyloxopyranylthiophenyl ester preparation; structure activity sulfamate hydroxyphenylethyloxopyranylthiophenyl ester preparation.

Dihydropyran-2-ones possessing a sulfamate moiety at the 4-position of a phenylthio ring were designed to reach S3′ pocket of the HIV protease. Synthetic routes for the preparation of thiotosylates possessing 3-(2-tert-butyl-5-methyl-4-sulfamate) phenylthio moiety were established. SAR of various sulfamate analogs including HIV protease binding affinities, antiviral activities and therapeutic indexes will be described. An example compound thus prepared and tested was sulfamic acid 4-[[5,6-dihydro-4-hydroxy-6-[2-(4-hydroxyphenyl)ethyl]-6-methyl-2-oxo-2H-pyran-3-yl]thio]-5-(1,1-dimethylethyl)-2-methylphenyl ester.

Bioorganic & Medicinal Chemistry Letters published new progress about Antiviral agents. 10305-42-7 belongs to class ethers-buliding-blocks, and the molecular formula is C3H8ClNO2S, Quality Control of 10305-42-7.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem