Category: 103-16-2

Catalyst-free photooxidation reaction from 1,4-dihydropyridazine to pyridazine under air was written by Karaki, Fumika;Kiguchi, Takuto;Itoh, Kennosuke;Sato, Noriko;Konishi, Kazuhide;Fujii, Hideaki. And the article was included in Tetrahedron in 2021.Reference of 103-16-2 The following contents are mentioned in the article:

In the inverse electron-demand Diels-Alder (iEDDA) reactions between tetrazines and strained alkenes, a mixture of 1,4-dihydropyridazine isomers are formed first, and they are then oxidized to pyridazines. Although the products of these related oxidation processes converge as pyridazines, the oxidation rate was quite low with some substrates. In this study, 1,4-dihydropyridazines formed in the iEDDA reactions were oxidized to pyridazines by simply irradiating with an UV light under an air atm. Exptl. results implied that singlet oxygen was formed in the course of the reactions to oxidize the 1,4-dihydropyridazine mols. This study involved multiple reactions and reactants, such as 4-Benzyloxyphenol (cas: 103-16-2Reference of 103-16-2).

4-Benzyloxyphenol (cas: 103-16-2) belongs to ethers. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Reference of 103-16-2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Catalyst-free photooxidation reaction from 1,4-dihydropyridazine to pyridazine under air was written by Karaki, Fumika;Kiguchi, Takuto;Itoh, Kennosuke;Sato, Noriko;Konishi, Kazuhide;Fujii, Hideaki. And the article was included in Tetrahedron in 2021.Computed Properties of C13H12O2 The following contents are mentioned in the article:

In the inverse electron-demand Diels-Alder (iEDDA) reactions between tetrazines and strained alkenes, a mixture of 1,4-dihydropyridazine isomers are formed first, and they are then oxidized to pyridazines. Although the products of these related oxidation processes converge as pyridazines, the oxidation rate was quite low with some substrates. In this study, 1,4-dihydropyridazines formed in the iEDDA reactions were oxidized to pyridazines by simply irradiating with an UV light under an air atm. Exptl. results implied that singlet oxygen was formed in the course of the reactions to oxidize the 1,4-dihydropyridazine mols. This study involved multiple reactions and reactants, such as 4-Benzyloxyphenol (cas: 103-16-2Computed Properties of C13H12O2).

4-Benzyloxyphenol (cas: 103-16-2) belongs to ethers. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Computed Properties of C13H12O2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Nickel-catalysed C-O bond reduction of 2,4,6-triaryloxy-1,3,5-triazines in 2-methyltetrahydrofuran was written by Wang, Yaoyao;Shen, Jun;Chen, Qun;Wang, Liang;He, Mingyang. And the article was included in Chinese Chemical Letters in 2019.Reference of 103-16-2 The following contents are mentioned in the article:

A nickel-catalyzed reduction of phenol derivatives activated by 2,4,6-trichloro-1,3,5-triazine (TCT) in ecofriendly 2-methyltetrahydrofuran (2-MeTHF) is described. The phenol-TCT derivatives were readily prepared using grinding method in short time without further purification This catalytic system allowed the facile C-O cleavage of phenol-TCT derivatives under mild reaction conditions with high efficiency and good functional group tolerance. Gram-scale reaction was also achieved. Particularly, sequential functionalization of phenol-TCT derivatives followed by C-O bond reduction could also be realized, affording the high value-added products in moderate to good yields. This study involved multiple reactions and reactants, such as 4-Benzyloxyphenol (cas: 103-16-2Reference of 103-16-2).

4-Benzyloxyphenol (cas: 103-16-2) belongs to ethers. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Reference of 103-16-2

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Chiral discrimination of 2-heptylaminium salt by planar-chiral monohydroxy-functionalized pillar[5]arenes was written by Al-Azemi, Talal F.;Vinodh, Mickey;Alipour, Fatemeh H.;Mohamod, Abdirahman A.. And the article was included in Organic Chemistry Frontiers in 2019.Computed Properties of C13H12O2 The following contents are mentioned in the article:

The synthesis of a planar-chiral monohydroxy-functionalized pillar[5]arene amenable to a wide variety of chem. modifications was reported. Chiral resolution was performed using derivatization with Mosher’s acid chloride (S)-(+)-α-methoxy-α-trifluoromethylphenylacetyl chloride ((S)-(+)-MTPA-Cl), and the absolute configurations of the thus obtained MTPA ester-functionalized pillar[5]arenes were determined by single-crystal X-ray diffraction. Finally, the effect of hydroxy groups on the temperature-dependent rotational movement of pillar[5]arene units was investigated by chiral HPLC and its application as a chiral receptor for alkyl aminium salts was demonstrated. This study involved multiple reactions and reactants, such as 4-Benzyloxyphenol (cas: 103-16-2Computed Properties of C13H12O2).

4-Benzyloxyphenol (cas: 103-16-2) belongs to ethers. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Computed Properties of C13H12O2

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

A low toxic CRM1 degrader: Synthesis and anti-proliferation on MGC803 and HGC27 was written by Xu, Hai-Wei;Jia, Shilong;Liu, Mengbo;Li, Xiaobo;Meng, Xia;Wu, Xinxin;Yu, Lu;Wang, Menglin;Jin, Cheng-Yun. And the article was included in European Journal of Medicinal Chemistry in 2020.Recommanded Product: 103-16-2 The following contents are mentioned in the article:

Chromosome region maintenance 1 (CRM1) is the sole nuclear exporter of several tumor suppressor, a growth regulatory protein as an attractive cancer drug target. In the present work, a novel CRM1 degrader was discovered from newly synthesized α, β-unsaturated-δ-lactone based on a natural product Goniothalamin. It induces apoptosis of both MGC803 and HGC27 cell lines via degrading CRM1. Selective inhibition was observed for the proliferation of gastric cancer cell lines MGC803, HGC27 comparing to Human Gastric Mucosal Epithelial Cell Line (GES1). For the first time, CRM1 inhibitor or degrader inducing apoptosis in gastric carcinoma was investigated. This study involved multiple reactions and reactants, such as 4-Benzyloxyphenol (cas: 103-16-2Recommanded Product: 103-16-2).

4-Benzyloxyphenol (cas: 103-16-2) belongs to ethers. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Recommanded Product: 103-16-2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

A low toxic CRM1 degrader: Synthesis and anti-proliferation on MGC803 and HGC27 was written by Xu, Hai-Wei;Jia, Shilong;Liu, Mengbo;Li, Xiaobo;Meng, Xia;Wu, Xinxin;Yu, Lu;Wang, Menglin;Jin, Cheng-Yun. And the article was included in European Journal of Medicinal Chemistry in 2020.Category: ethers-buliding-blocks The following contents are mentioned in the article:

Chromosome region maintenance 1 (CRM1) is the sole nuclear exporter of several tumor suppressor, a growth regulatory protein as an attractive cancer drug target. In the present work, a novel CRM1 degrader was discovered from newly synthesized α, β-unsaturated-δ-lactone based on a natural product Goniothalamin. It induces apoptosis of both MGC803 and HGC27 cell lines via degrading CRM1. Selective inhibition was observed for the proliferation of gastric cancer cell lines MGC803, HGC27 comparing to Human Gastric Mucosal Epithelial Cell Line (GES1). For the first time, CRM1 inhibitor or degrader inducing apoptosis in gastric carcinoma was investigated. This study involved multiple reactions and reactants, such as 4-Benzyloxyphenol (cas: 103-16-2Category: ethers-buliding-blocks).

4-Benzyloxyphenol (cas: 103-16-2) belongs to ethers. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Category: ethers-buliding-blocks

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Synthesis of ¹⁸F-Labeled Aryl Fluorosulfates via Nucleophilic Radiofluorination was written by Kwon, Young-Do;Jeon, Min Ho;Park, Nam Kyu;Seo, Jeong Kon;Son, Jeongmin;Ryu, Young Hoon;Hong, Sung You;Chun, Joong-Hyun. And the article was included in Organic Letters in 2020.Synthetic Route of C13H12O2 The following contents are mentioned in the article:

Sulfuryl fluoride gas is a key reagent for SO₂F transfer. However, conventional SO₂F transfer reactions have limited ¹⁸F-radiochem. translation, due to the inaccessibility of gaseous [¹⁸F]SO₂F₂. Herein, we report the first SO₂F₂-free synthesis of aryl [¹⁸F]fluorosulfates from both phenolic and isolated aryl imidazylate precursors with cyclotron-produced ¹⁸F^–. The radiochem. yields ranged from moderate to good with excellent functional group tolerance. The reliability of our approach was validated by the automated radiosynthesis of 4-acetamidophenyl [¹⁸F]fluorosulfate. This study involved multiple reactions and reactants, such as 4-Benzyloxyphenol (cas: 103-16-2Synthetic Route of C13H12O2).

4-Benzyloxyphenol (cas: 103-16-2) belongs to ethers. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Synthetic Route of C13H12O2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Synthesis of ¹⁸F-Labeled Aryl Fluorosulfates via Nucleophilic Radiofluorination was written by Kwon, Young-Do;Jeon, Min Ho;Park, Nam Kyu;Seo, Jeong Kon;Son, Jeongmin;Ryu, Young Hoon;Hong, Sung You;Chun, Joong-Hyun. And the article was included in Organic Letters in 2020.Product Details of 103-16-2 The following contents are mentioned in the article:

Sulfuryl fluoride gas is a key reagent for SO₂F transfer. However, conventional SO₂F transfer reactions have limited ¹⁸F-radiochem. translation, due to the inaccessibility of gaseous [¹⁸F]SO₂F₂. Herein, we report the first SO₂F₂-free synthesis of aryl [¹⁸F]fluorosulfates from both phenolic and isolated aryl imidazylate precursors with cyclotron-produced ¹⁸F^–. The radiochem. yields ranged from moderate to good with excellent functional group tolerance. The reliability of our approach was validated by the automated radiosynthesis of 4-acetamidophenyl [¹⁸F]fluorosulfate. This study involved multiple reactions and reactants, such as 4-Benzyloxyphenol (cas: 103-16-2Product Details of 103-16-2).

4-Benzyloxyphenol (cas: 103-16-2) belongs to ethers. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Product Details of 103-16-2

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Chirality driven mesomorphic behaviour difference: dichiral compounds containing two lactate groups was written by Wu, Xiaoqing;Wu, Limin;Guo, Yongmin;Li, Yi;Li, Baozong;Yang, Yonggang. And the article was included in Liquid Crystals in 2020.SDS of cas: 103-16-2 The following contents are mentioned in the article:

Four compounds containing two lactate groups and one perfluorocarbon chain were designed and synthesized, whose chirality was tuned by changing the chirality of the lactic acid residues. (R,S)- And (S,R)- stereoisomers exhibited an enantiotropic SmA phase, while (R,R)- and (S,S)-stereoisomers exhibited an enantiotropic SmA phase and an enantiotropic SmCd* one. Therefore, the chirality of the compounds played an important role in the mesomorphic behaviors of the compounds The optical activity of these liquid crystals was dominated by the chirality of the lactate group near the core. (R)- And (S)- with one lactic acid residue and one perfluorocarbon chain exhibited only an enantiotropic SmA phase. This study involved multiple reactions and reactants, such as 4-Benzyloxyphenol (cas: 103-16-2SDS of cas: 103-16-2).

4-Benzyloxyphenol (cas: 103-16-2) belongs to ethers. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. SDS of cas: 103-16-2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Chirality driven mesomorphic behaviour difference: dichiral compounds containing two lactate groups was written by Wu, Xiaoqing;Wu, Limin;Guo, Yongmin;Li, Yi;Li, Baozong;Yang, Yonggang. And the article was included in Liquid Crystals in 2020.Quality Control of 4-Benzyloxyphenol The following contents are mentioned in the article:

Four compounds containing two lactate groups and one perfluorocarbon chain were designed and synthesized, whose chirality was tuned by changing the chirality of the lactic acid residues. (R,S)- And (S,R)- stereoisomers exhibited an enantiotropic SmA phase, while (R,R)- and (S,S)-stereoisomers exhibited an enantiotropic SmA phase and an enantiotropic SmCd* one. Therefore, the chirality of the compounds played an important role in the mesomorphic behaviors of the compounds The optical activity of these liquid crystals was dominated by the chirality of the lactate group near the core. (R)- And (S)- with one lactic acid residue and one perfluorocarbon chain exhibited only an enantiotropic SmA phase. This study involved multiple reactions and reactants, such as 4-Benzyloxyphenol (cas: 103-16-2Quality Control of 4-Benzyloxyphenol).

4-Benzyloxyphenol (cas: 103-16-2) belongs to ethers. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Quality Control of 4-Benzyloxyphenol

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem