《Catalytic Ynone-Amidine Formal [4 + 2]-Cycloaddition for the Regioselective Synthesis of Tricyclic Azepines》 was written by Reddy, T. Prabhakar; Gujral, Jagjeet; Roy, Pritam; Ramachary, Dhevalapally B.. COA of Formula: C9H10O2This research focused onynone amidine calcium cycloaddition catalyst; azepine tricyclic stereoselective preparation. The article conveys some information:
A Ca(OTf)2- and self-promoted ynone-amidine atom-economic formal [4 + 2]-cycloaddition of various ynones with amidines is reported for the construction of highly functionalized tricyclic azepines. High reaction rate, ease of operation, and high product selectivity with wide substrate scope are the key advantages of the present annulation protocol. The experimental part of the paper was very detailed, including the reaction process of 2-(Benzyloxy)acetaldehyde(cas: 60656-87-3COA of Formula: C9H10O2)
2-(Benzyloxy)acetaldehyde(cas: 60656-87-3) is a non-natural aldehyde. It undergoes enantioselective Mukaiyama aldol reaction with silylketene acetal nucleophiles in the presence of C2-symmetric bis(oxazolinyl)pyridine Cu(II) complex (catalyst).COA of Formula: C9H10O2
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem