In 2019,Methods and Protocols included an article by Martins, Ines S.; Coelho, Jaime A. S.. Application In Synthesis of N,N-Dimethylformamide Dimethyl Acetal. The article was titled 《Solvent-free synthesis of 2,5-bis((dimethylamino)methylene)cyclopentanone》. The information in the text is summarized as follows:
The important feature in synthesis of ketocyanine dyes precursor 2,5-bis((dimethylamino)methylene)cyclopentanone I through organocatalyzed condensation of cyclopentanone and N,N-dimethylformamide di-Me acetal was removal of methanol produced during the reaction. By studying reaction profile, in particular selectivity for formation of mono- and bis-condensation products, a high yield of desired product could be obtained through an operationally simple and solvent-free protocol.N,N-Dimethylformamide Dimethyl Acetal(cas: 4637-24-5Application In Synthesis of N,N-Dimethylformamide Dimethyl Acetal) was used in this study.
N,N-Dimethylformamide Dimethyl Acetal(cas: 4637-24-5) belongs to anime. Aniline, ethanolamines, and several other amines are major industrial commodities used in making rubber, dyes, pharmaceuticals, and synthetic resins and fibres and for a host of other applications. Most of the numerous methods for the preparation of amines may be broadly divided into two groups: (1) chemical reduction (replacement of oxygen with hydrogen atoms in the molecule) of members of several other classes of organic nitrogen compounds and (2) reactions of ammonia or amines with organic compounds.Application In Synthesis of N,N-Dimethylformamide Dimethyl Acetal
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem