Xu, Baijie; Liu, Zhihao; Xu, Qiaofei; Han, Xiao; Ma, Xinyi; Wang, Jiawei; Kannan, Thirumurthy; Ma, Pengtao; Wang, Jingping; Niu, Jingyang published an article in 2021. The article was titled 《Polyoxomolybdates as efficient catalysts for Knoevenagel condensation reaction of benzaldehyde and ethyl cyanoacetate under mild condition》, and you may find the article in Journal of Materials Science.Application In Synthesis of 2-Methoxybenzaldehyde The information in the text is summarized as follows:
The development of new heterogeneous catalysts for Knoevenagel condensation reaction is critical for practical applications. Herein, authors prepared three organophosphonate-functionalized polyoxomolybdates, Cs2Na9H9[{Co(H2O)4}(TeMo6O21)2{Co(OOCCH2NCH2PO3)2}3]·41H2O (1), Cs2Na8[H6{Co(H2O)4}3(SeMo6O21)2{Co(OOCCH2NCH2PO3)2}3]·31H2O (2) and Cs2Na9H3[H6{Ni(H2O)4}(SeMo6O21)2{Ni(OOCCH2NCH2PO3)2}3]·28H2O (3), which exhibit high catalytic activity for gram-scale Knoevenagel condensation of benzaldehyde with Et cyanoacetate. Especially, under the optimal conditions, compound 1 can achieve a satisfactory yield (98%) and show high TON value (1960), which is superior to that of compounds 2 and 3. Notably, the TON value is much higher than that of previously reported catalysts. Such high catalytic performance could be attributed to the co-existence of Lewis acid and Lewis base sites in catalysts. In addition, based on substrates screening and recyclability tests, 1 has exhibited broad catalytic generality and good recyclability. In the experiment, the researchers used many compounds, for example, 2-Methoxybenzaldehyde(cas: 135-02-4Application In Synthesis of 2-Methoxybenzaldehyde)
2-Methoxybenzaldehyde(cas: 135-02-4) is found in cassia oil, cinnamon bark, and cinnamon bark oil. It is a clear colorless liquid with a strong aroma. It has been used to examine the acaricidal activity of Periploca sepium oil and its active component against Tyrophagus putrescentiae.Application In Synthesis of 2-Methoxybenzaldehyde
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem